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Adipose-Derived Stem Cells Cocultured with Chondrocytes Promote the Proliferation of Chondrocytes
Published 2017-01-01“…The study on the mechanism of this coculture system indicated that the role of this coculture system is similar to the function of TGF-β1 in the promotion of chondrocytes.…”
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The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model
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Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus
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Exploring therapeutic strategies for androgen-independent prostate cancer using a magnetic coculture platform
Published 2025-06-01Subjects: “…Magnetic coculture platform…”
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Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture
Published 2025-01-01“…Based on these results, new coculture systems of disease‐relevant cells are developed to simulate human secondary lymphoid tissues ex vivo. …”
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Therapeutic Benefit in Rheumatoid Cachexia Illustrated Using a Novel Primary Human Triple Cell Coculture Model
Published 2022-01-01“…Exposure of the triple coculture to RATN and RATNR serum resulted in dysregulated myoblast proliferation and growth, and ECM impairment, which was reversed by BMP-7 treatment.…”
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Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages
Published 2018-01-01“…We established a model of microencapsulated SGC7901 human GC cells and evaluated the effects of coculturing spheres with tumor-associated macrophages (TAMs). …”
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Coculture with Eastern oysters is unlikely to reduce OsHV-1 impacts to farmed Pacific oysters: A modelling approach
Published 2025-03-01“…Simulation results indicated that introducing C. virginica did not impede OsHV-1 progression; even in the M. gigas/C. virginica 10/90 system, M. gigas mortality reached its maximum, albeit delayed by approximately 10 days. Coculture scenarios did not provide a significant advantage for M. gigas, likely due to OsHV-1 particle saturation in the water column. …”
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Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids
Published 2023-01-01“…Monoculture and βH5/HUVEC cocultures formed compact spheroids within 7 days, with average diameter ~140 μm. …”
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The use of a benign fast-growing cyanobacterial species to control microcystin synthesis from Microcystis aeruginosa
Published 2024-12-01Subjects: “…coculture…”
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Erratum: The use of a benign fast-growing cyanobacterial species to control microcystin synthesis from Microcystis aeruginosa
Published 2025-01-01Subjects: “…coculture…”
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Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons
Published 2017-01-01“…We aim to identify levels of signal factors secreted by MSCs cultured in 2D monolayers (2D-MSCs), spheroids (spheroids MSCs), and cocultures of microvesicles (MVs) derived from 2D-MSCs or spheroid MSCs and retinal photoreceptor neurons. …”
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Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells
Published 2018-01-01“…Functional GJs in cocultures were inhibited when the expression of the Cx43 protein was downregulated. …”
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Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System
Published 2018-01-01“…We found that the proliferation and multipotent differentiation of BMSCs were all enhanced in the coculture group compared to the BMSCs group. Crystal violet staining showed that the clone-forming ability of BMSCs in the coculture group was also enhanced and mRNA levels of Sox2, Nanog, and Oct4 were significantly upregulated in the coculture group. …”
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Fibroblast Growth Factor 18 Increases the Trophic Effects of Bone Marrow Mesenchymal Stem Cells on Chondrocytes Isolated from Late Stage Osteoarthritic Patients
Published 2014-01-01“…Coculture of mesenchymal stem cells with chondrocytes increases production of cartilaginous matrix. …”
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Hematopoietic Stem and Progenitor Cell Expansion in Contact with Mesenchymal Stromal Cells in a Hanging Drop Model Uncovers Disadvantages of 3D Culture
Published 2016-01-01“…In terms of HSPC proliferation, the conventional 2D coculture system was superior to the hanging drop model. …”
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Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling
Published 2021-01-01“…We found that the proliferation and apoptosis of DPCs and PDLCs were inhibited, and their cell cycles were arrested at the G0/G1 phase after coculture. Oct-4, Sox2, and STAT3 expression significantly increased and PAX5 expression decreased in the coculture systems. …”
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Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells
Published 2022-01-01“…Mechanically, we found that metformin-treated M2 macrophages possessed more potent osteoinductive capacity in our coculture system. Molecularly, these metformin-stimulated M2 macrophages facilitated osteogenesis via activating the PI3K/AKT/mTOR pathway. …”
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Kupffer Cells Promote the Differentiation of Adult Liver Hematopoietic Stem and Progenitor Cells into Lymphocytes via ICAM-1 and LFA-1 Interaction
Published 2019-01-01“…A blockade of intercellular cell adhesion molecule-1 (ICAM-1) in a liver HSPC and kupffer cell coculture system impaired the adhesion, expansion, and differentiation of HSPCs. …”
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