Relationship between age and delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage requiring invasive mechanical ventilation: a secondary analysis by Qing-qing Wu, Wei-wen Chen, Tian-lai Lin, Cun-rong Chen, Zhi-rong Ding, You-li Chen

“…After adjusting for confounding variables, for patients aged < 53 years, the risk of DCI increased by 14% (OR, 1.14; 95% CI 1.05–1.23) for each 1-year increase in age. For patients aged 53 to 77 years, the risk of DCI decreased by 19% (OR, 0.81; 95% CI 0.73–0.88) for each 1-year increase. …”
Get full text

Achieving prediabetes reversal in China: a nationwide longitudinal study on the role of blood glucose and lipid management in middle-aged and elderly adults by Hongguang Yang, Yao Liu, Zhenhe Huang, Guifang Deng

“…The stepwise logistic regression model identified older age, female sex, abdominal obesity (OR 0.70, 95% CI 0.57–0.86), elevated LDL-C (OR 0.69, 95% CI 0.48–0.97), higher FPG (OR 0.68, 95% CI 0.52–0.90), and higher HbA1c (OR 0.23, 95% CI 0.18–0.30) as factors associated with regression to NGR. …”
Get full text

Association between triglyceride/high density lipoprotein ratio and incidence risk of Parkinson’s disease: a population-based cohort study by Yoonkyung Chang, Ju-young Park, Tae-Jin Song

“…Considering the multivariable time-dependent Cox proportional hazard model with repeated measures of average TG/HDL cholesterol ratio, a per unit increase in TG/HDL cholesterol ratio significantly increased the risk of PD in the entire cohort (hazard ratio (HR), 1.010; 95% confidence interval (CI), 1.001–1.020). These repeated measures of the average TG/HDL cholesterol ratio were associated with the incidence risk of PD in a J-shaped pattern for the entire diabetes mellitus (DM) and non-DM cohorts in restricted cubic spline analysis. …”
Get full text

Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis by Junbin Liao, Junbin Liao, Wenfeng Cai, Danrong Lin, Yuanyun Xiao, Yanxi Liu, Yahui Wang, Yuquan Zhong, Fan Xiao, Heng Fang, Yilu Yao, Yunfeng Lin, Jiewen Su, Siyu Sun, Bo Zhang, Yan Wang, Wei Zhu, Wei Zhu

“…A multivariable ordinal logistic regression model was employed to analyze the influence of various factors and the DII on the degree of disability among older adults. Restricted cubic spline and sensitivity analyses were used to assess the association between DII and the degree of disability of the older adult population.ResultsInactivity (never exercising, OR = 8.48, 95% CI = 2.30–31.31) and reduced activity (formerly exercising, OR = 4.85, 95% CI = 1.39–16.96), stroke (OR = 2.78, 95% CI = 1.61–4.80), and dementia (OR = 2.69, 95% CI = 1.26–5.78) were significantly associated with increased disability. …”
Get full text

Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy by SiQin Xiu, Li Tang, Chengjie Qin, Di Tian, Yuhong Chen, Lingling Gu, Liu Yang, Yuhao Sun, Xinghui Liu, Yonghong Lin, Yumei Wang

“…Compared to an IPI of 24–59 months, the risk of PTB was significantly higher with an IPI of ≥ 120 months for women aged ≥ 35 years (aOR,1.17; 95% CI, 0.89–1.55) and 30–34 years (aOR 2.17; 95% CI, 1.59–2.92), but not for those aged ≤ 29 years (aOR 1.34; 95% CI, 0.20–5.31). …”
Get full text

Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study by Zhongchen Li, Chunyu Yu, Heng Zhang, Runze Chen, Yan Zhao, Zhe Zheng

“…Each 1-SD increase in remnant-C was associated with a 6.6% higher risk of MACCEs (HR: 1.066, 95% CI 1.012–1.124), a 7.1% higher risk of all-cause death (HR: 1.071, 95% CI 1.008–1.209), and an 11.2% higher risk of myocardial infarction (HR: 1.112, 95% CI 1.011–1.222). …”
Get full text

Effect of Admission Serum Calcium Levels and Length of Stay in Patients with Acute Pancreatitis: Data from the MIMIC-III Database by Dongyan Wang, Xiaoyan Guo, Wenwen Xia, Zhijuan Ru, Yihai Shi, Zhengyu Hu

“…In addition, compared with patients with blood calcium <8.5 mg/dl, multivariate logistic regression analysis showed that patients with blood calcium ≥8.5 mg/dl had a reduced risk of the LOS >2 days (aOR = 0.653; 95% CI 0.507–0.842; p=0.001), a reduced risk of the LOS >5 days (aOR = 0.589; 95% CI 0.503–0.689; p<0.001), and a reduced risk of the LOS >7 days (aOR = 0.515; 95% CI 0.437–0.609; p<0.001). …”
Get full text

Analysis of respiratory pathogen detection in hospitalized children with acute respiratory tract infections after ending the zero COVID policy by Xuena Xu, Yizhu Zhang, Lina Xu, Wujun Jiang, Chuangli Hao

“…The greatest increase in MP positivity was 316.9% in the 3–5 years (OR: 5.5, 95% CI: 4.9–6.1). After ending the zero COVID policy, the RSV-positive rate increased most in summer, while HRV was predominantly circulated in spring and the MP-positive rate peaked in autumn. …”
Get full text

Dietary practice and associated factors among lactating mothers in Dangila District in the Awi Zone Amhara region Ethiopia, 2022: a cross-sectional study by Sileshi Mulatu, Getasew Mulatu, Azeb Gedif

“…Additionally, daily laborers exhibited a striking 9.35 times higher likelihood of poor dietary practices (AOR = 9.35; 95% CI: 8.02, 19.96), and food-insecure mothers had 4.93 times higher odds of inadequate nutrition (AOR = 4.93; 95% CI: 3.40, 7.16).ConclusionIn conclusion, the dietary practices of lactating mothers were found to be suboptimal, falling below WHO and FAO recommendations. …”
Get full text

Blood metal levels predict digestive tract cancer risk using machine learning in a U.S. cohort by Chenyuan Shi, Hanfeng Jiang, Fangzhou Zhao, Yigang Zhang, Haoming Chen

“…Logistic regression analysis revealed significant associations between higher K (odds ratio [OR] = 7.58, 95% CI: 3.48–16.48, P < 0.0001), Cd (OR = 1.06, 95% CI: 1.04–1.08, P < 0.0001), and Pb (OR = 7.60, 95% CI: 3.26–17.72, P < 0.0001) levels and EC risk. …”
Get full text

Association of workforce participation with depression among US older adults: results from NHANES 2005–2018 by Zhenyu Sun, Yi Wang, Xi Chen, Dongfu Qian

“…There was a significantly negative association of PHQ-9 score with working (Exp [β] = 0.68; 95%CI: 0.53–0.87), working as private employee (Exp [β] = 0.67; 95%CI: 0.50–0.89), or working on regular daytime (Exp [β] = 0.65; 95%CI: 0.52–0.82). …”
Get full text

Triglyceride glucose index–body mass index as a predictor of coronary artery disease severity in patients with H-type hypertension across different glucose metabolic states by Lian Wang, Zijin Li, Rui Qiu, Li Luo, Xisheng Yan

“…The TyG-BMI was categorized into tertiles and analyzed using logistic regression models and restricted cubic spline (RCS) models to assess its association with multi-vessel CAD. …”
Get full text

Indirect treatment comparison of lanadelumab and a C1-esterase inhibitor in pediatric patients with hereditary angioedema by Maureen Watt, Rachel Goldgrub, Mia Malmenas, Katrin Haeussler

“…These were for lanadelumab (SPRING, NCT04070326) and intravenous-C1-esterase inhibitor (C1-INH[IV], NCT02052141). …”

The association between serum albumin levels and metabolic syndrome based on the NHANES and two sample Mendelian randomization study by Yile Tang, Yong Fan, Jin Su, Zisen Yang, Zaoling Liu

“…In the forward MR study, the IVW method revealed that genetic predicted increased levels of serum albumin were positively correlated with metabolic syndrome (OR: 1.149, 95% CI: 1.016–1.299) and its components, including hypertension (OR: 1.130, 95% CI: 1.013–1.260) and triglycerides (OR: 1.343, 95% CI: 1.209–1.492). …”
Get full text

The Association of moisture intake and constipation among us adults: evidence from NHANES 2005–2010 by Deng-Chao Wang, Xue-Feng Peng, Wen-Xing Chen, Miao Yu

“…After adequately adjusting for confounders, a significant negative correlation was observed between moisture intake and constipation risk (OR 0.81; 95% CI: 0.74–0.89). Quartile analysis of moisture intake demonstrated that, compared to the first quartile Q1 (0.06 to 1.90 kg), the constipation risk for the second quartile Q2 (1.91 to 2.53 kg), third quartile Q3 (2.54 to 3.36 kg), and fourth quartile Q4 (3.37 to 16.97 kg) were OR 0.80 (95% CI: 0.64–0.72), OR 0.57 (95% CI: 0.45–0.72), and OR 0.54 (95% CI: 0.44–0.67) respectively, with a trend test P-value ofless than 0.001. …”
Get full text

Association between obesity and thyroid nodules in children and adults living in iodine-sufficient areas: analysis of cross-sectional data from Tianjin, China by Yang Wang, Fang Li, Dandan Zhang, Wenfeng Li, Yani Duan, Yushan Cui

“…In adults, a high BSA (OR=1.34, 95% CI 1.01 to 1.77) was significantly associated with multiple thyroid nodules, but this association was not valid in the restricted cubic spline model.Conclusion Childhood obesity is associated with the risk of thyroid nodules; however, there is no clear association between adult obesity and thyroid nodules.…”
Get full text

Association of systemic immune-inflammation index with all-cause and cardiovascular mortality among adults with depression: evidence from NHANES 2005–2018 by Xinping Yu, Heqing Zheng, Mingxu Liu, Lanxiang Wu, Sheng Tian, Wei Wu

“…Cox proportional hazards regression models to compute hazard ratios (HR) and 95% confidence intervals (CI) for mortality.The restricted cubic spline(RCS), Kaplan-Meier curve analysis, time-dependent ROC analysis, subgroup and sensitivity analyses were also used. …”
Get full text

KLRB1 expression in nasopharyngeal mucosa as a prognostic biomarker in COVID-19 patients by Marilina García-Aranda, María Ángeles Onieva, Desirée Martín-García, Raúl Quirós, Inmaculada López, María Padilla-Ruiz, Teresa Téllez, Beatriz Martínez-Gálvez, María Luisa Hortas, Alberto García-Galindo, José González-Gomariz, Rubén Armañanzas, Francisco Rivas-Ruiz, Alfonso Serrano, Isabel Barragán-Mallofret, Maximino Redondo

“…We analyzed nasopharyngeal exudates from 95 hospitalized patients in 2020 using high-plex RNA quantification on the NanoString® nCounter platform. Comparative analysis identified four genes, with KLRB1 (Killer cell lectin like receptor B1) (Odds Ratio OR 0.5, 95% CI: 0.27–0.96), along with age (OR 3.3, 95% CI: 1.25–8.93) emerging as independent prognostic markers in multivariate analysis. …”
Get full text

Is There a Nonlinear Relationship between Serum Uric Acid and Lipids in a Hypertensive Population with eGFR ≥30 ml/min/1.73 m2? Findings from the China Hypertension Registry Study... by Yu Yu, Xiao Huang, Minghui Li, Congcong Ding, Lihua Hu, Xiao Zhong, Wei Zhou, Tao Wang, Lingjuan Zhu, Huihui Bao, Xiaoshu Cheng

“…In the fully adjusted model, the results showed a positive correlation between SUA and TG (β = 0.15; 95% CI: 0.14, 0.16) and LDL-C (β = 0.06; 95% CI: 0.05, 0.07), respectively. …”
Get full text

The risk of malnutrition as a predictor of arrhythmia recurrence after catheter ablation in patients with paroxysmal non-valvular atrial Fibrillation and heart failure with preserv... by Zixi Zhang, Cancan Wang, Qiming Liu, Yichao Xiao, Jiabao Zhou, Keke Wu, Yunying Huang, Zeying Zhang, Shiping Liu, Qiuzhen Lin

“…Adjusted analyses showed that higher CONUT scores (HR: 10.132; 95% CI: 2.545-40.336; P =  0.001), lower NRI (HR: 22.734; 95% CI: 6.399-80.776; P <  0.001), or lower PNI (HR: 9.469; 95% CI: 3.232-27.739; P <  0.001) were significantly associated with increased risk of AF recurrence. …”
Get full text