One-year Prevalence, Comorbidities, and Cost of Hospitalizations for Alpha-1 Antitrypsin Deficiency among Patients with Chronic Obstructive Pulmonary Disease in the United States by Christopher M. Blanchette, Emily Zacherle, Joshua M. Noone, Bryce A. Van Doren, Debosree Roy, Reuben Howden

“…**Objectives:** Little is known about severe chronic obstructive pulmonary disease (COPD) exacerbations among patients with Alpha-1 Antitrypsin Deficiency (AATD). …”
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Thresholds of handgrip strength for all-cause mortality in patients with chronic kidney disease: a secondary systematic review with dose-response meta-analysis by Hao Chen, Fan Zhang, Liuyan Huang, Yan Bai, Yifei Zhong, Yi Li

“…Background Although handgrip strength is associated with all-cause mortality in patients with chronic kidney disease (CKD), whether this relationship is dose-related is unknown. …”
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Defining patient-reported outcomes in diabetes, obesity, cardiovascular disease, and chronic kidney disease for clinical practice guidelines - perspectives of the taskforce of the... by Katharine Barnard-Kelly, Tadej Battelino, Frank C. Brosius, Antonio Ceriello, Francesco Cosentino, James R. Gavin, Francesco Giorgino, Jennifer Green, Linong Ji, Monika Kellerer, Sue Koob, Mikhail Kosiborod, Nebojsa Lalic, Nikolaus Marx, Prashant Nedungadi, Christopher G. Parkin, Helena W. Rodbard, René D. Rötzer, Lars Rydén, Wayne Huey-Herng Sheu, Eberhard Standl, Britta Tendal Jeppesen, Pinar Topsever, Per Olav Vandvik, Christoph Wanner, Oliver Schnell

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Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

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Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide pros... by Gaoshu Zheng, Jijie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jianghua Zhou

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Fractures and Chronic Recurrence are Commonly Associated with Ankle Sprains: a 5-year Population-level Cohort of Patients Seen in the U.S. Military Health System by Daniel I Rhon, Tina A Greenlee, Chad E Cook, Richard B Westrick, Jon A Umlauf, John J Fraser

“…Recurrence in this cohort approximates the 40% previously reported in individuals with first-time ankle sprain who progress to chronic ankle instability. Future epidemiological studies should consider reporting on subcategories of ankle sprain injuries to provide a more granular assessment of the distribution of severity…”
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Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…Discussion This protocol outlines a novel approach to evaluating the O2O digital health service model for chronic disease management. It offers insights into the nuanced effects of the intervention, highlighting the potential for tailoring future interventions for maximum benefit. …”
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Effectiveness of Electronic Quality Improvement Activities to Reduce Cardiovascular Disease Risk in People With Chronic Kidney Disease in General Practice: Cluster Randomized Trial... by Jo-Anne Manski-Nankervis, Barbara Hunter, Natalie Lumsden, Adrian Laughlin, Rita McMorrow, Douglas Boyle, Patty Chondros, Shilpanjali Jesudason, Jan Radford, Megan Prictor, Jon Emery, Paul Amores, An Tran-Duy, Craig Nelson

“… BackgroundFuture Health Today (FHT) is a program integrated with electronic medical record (EMR) systems in general practice and comprises (1) a practice dashboard to identify people at risk of, or with, chronic disease who may benefit from intervention; (2) active clinical decision support (CDS) at the point of care; and (3) quality improvement activities. …”
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Current perspectives and trends of the research on hypertensive nephropathy: a bibliometric analysis from 2000 to 2023 by Lan Wang, Jingyu Wang, Yuemiao Zhang, Hong Zhang

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Enhancing Chronic Disease Prediction in IoMT-Enabled Healthcare 5.0 Using Deep Machine Learning: Alzheimer’s Disease as a Case Study by Rabia Javed, Tahir Abbas, Tariq Shahzad, Khadija Kanwal, Sadaqat Ali Ramay, Muhammad Adnan Khan, Khmaies Ouahada

“…Chronic disease significantly affects health on a global scale. …”
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Combined Liver Stiffness and Α-fetoprotein Further beyond the Sustained Virologic Response Visit as Predictors of Long-Term Liver-Related Events in Patients with Chronic Hepatitis... by Sheng-Hung Chen, Hsueh-Chou Lai, Wen-Pang Su, Jung-Ta Kao, Po-Heng Chuang, Wei-Fan Hsu, Hung-Wei Wang, Tsung-Lin Hsieh, Hung-Yao Chen, Cheng-Yuan Peng

“…Long-term risk stratification using combined liver stiffness (LS) and clinically relevant blood tests acquired at the baseline further beyond the sustained virologic response (SVR) visit for chronic hepatitis C (CHC) has not been thoroughly investigated. …”
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Economic burden of chronic obstructive pulmonary disease and post-tuberculosis sequelae in low- and middle-income countries: a database compiled from a systematic review and meta-a... by Fabrizio Tediosi, Klaus Reither, Olivia Keiser, Alexandra Walker, Yuling Lin, Marguerite Batta, Sierra Ottilie-Kovelman, Anna Duchenko, Curdin Brugger, Robert S Wallis, Marina Antillon

“…Background Chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) impose a substantial economic burden globally. …”
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Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers by Pablo E. Pergola, Melanie S. Joy, Armando Garsd, Steve J. Hasal, Atul Khare, Guru Reddy, Pramod Gupta, William F. Finn

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Proteomic profiling of serum in cats with naturally occurring degenerative joint disease and co-morbid conditions by B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles, Rakesh Ponnala, Steven G. Kamerling, Tracey Williams

“…Almost 70% of cats with DJD-associated pain suffer the co-morbidity of chronic kidney disease (CKD). There are currently very limited treatment or management options. …”
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Intravoxel Incoherent Motion (IVIM) Diffusion-Weighted Imaging (DWI) in Patients with Liver Dysfunction of Chronic Viral Hepatitis: Segmental Heterogeneity and Relationship with Ch... by Lei Ding, Lianxiang Xiao, Xiangtao Lin, Chunmei Xiong, Lingbo Lin, Shijun Chen

“…The aim of the study was to evaluate the differences of liver IVIM parameters among liver segments in cirrhotic livers (chronic viral hepatitis). Material and Methods. This was a retrospective study of 82 consecutive patients with chronic liver disease who underwent MRI examination at the Jinan Infectious Diseases Hospital between January 2015 and December 2016. …”
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High CXCR3 on Leukemic Cells Distinguishes IgHVmut from IgHVunmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones by Gayane Manukyan, Tomas Papajik, Zuzana Mikulkova, Renata Urbanova, Veronika Smotkova Kraiczova, Jakub Savara, Milos Kudelka, Peter Turcsanyi, Eva Kriegova

“…Despite the shared pattern of surface antigens, neoplastic cells in chronic lymphocytic leukemia (CLL) are highly heterogeneous in CD5 expression, a marker linked to a proliferative pool of neoplastic cells. …”
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The computerized algorithm for renal assessment improves diagnostic accuracy of renal impairment in hospitalized patients by Chun-You Chen, Te-I. Chang, Cheng-Hsien Chen, Shih-Chang Hsu, Yen-Ling Chu, Nai-Jen Huang, Yuh-Mou Sue, Tso-Hsiao Chen, Po-Hsun Huang, Chung-Te Liu, Hui-Ling Hsieh

“…A computerized algorithm was constructed to identify AKI events and chronic kidney disease (CKD) in these patients. Previous SCr tests were reviewed to define baseline SCr levels. …”
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A Comparative Study between Conventional Diaphragmatic Breathing Exercise and Virtual Reality-based Diaphragmatic Breathing Exercise on Quality of Life in Chronic Obstructive Pulmo... by Sridhar Shirodkar, Medha Deo

“…We propose the use of a novel VR-based approach as a respiratory biofeedback to improve breathing patterns in chronic obstructive pulmonary disease (COPD) patients, decrease their work of breathing, and improve breathing control. …”
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Associations of Serum Cystatin C, DNAm Cystatin C, Renal Function, and Mortality in U.S. Adults by Yu-Wei Fang, Wei-Chung Huang, Chikang Wang, Chien-Yu Lin

“…This association was particularly pronounced in participants without chronic kidney disease (CKD), with a <i>p</i>-value for the interaction between DNAmCystatinC and CKD on all-cause mortality of 0.002. …”
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Health care utilization patterns of patients enrolled in an interdisciplinary program for back pain by Sara Davin, Psy.D., MPH, Brittany Lapin, PhD., MPH, Belinda Udeh, PhD, Sarah Rispinto, PhD, Nicolas R. Thompson, MS, Ryan Honomichl, PhD, Andre Machado, MD, Irene L. Katzan, MD

“…Background: Chronic low back pain is a costly condition and the leading cause of disability worldwide. …”
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