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441
Benefits, limits, and risks of ChatGPT in medicine
Published 2025-01-01“…This heterogeneity in evidence quality necessitates a structured approach to future research and implementation.…”
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442
Considerations and experiences with healthcare-seeking during the first COVID-19 lockdown in Denmark
Published 2025-01-01“…Aim To (1) examine considerations before and experiences with GP contact during the first COronaVIrus Disease 2019 (COVID-19) lockdown among Danish citizens; (2) analyse the associations with sex, age, chronic disease, and socioeconomic factors; and (3) explore changes in healthcare-seeking behaviour post-pandemic.Method A total of 100,000 Danes aged 20 years or older, randomly selected in the general population, were invited to participate in a survey examining considerations and experiences with healthcare seeking during the first COVID-19 lockdown. …”
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443
Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities
Published 2025-01-01“…Additionally, emerging research on the microbiome and inflammation-related biomarkers, such as microRNAs (miRNAs) and exosomes, points to new opportunities for early detection and precision medicine. Future approaches to OC treatment must focus on personalized strategies that target the inflammatory TME, integrating anti-inflammatory therapies with immunotherapy to enhance patient outcomes. …”
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444
The Effects of POWER Training in Young and Older Adults after Stroke
Published 2016-01-01“…Data was analyzed from 16 individuals with chronic stroke who participated in 24 sessions of POWER training. …”
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445
Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome
Published 2025-01-01“…Abstract Background Sjogren syndrome (SS) is a chronic systemic autoimmune disease and its pathogenesis often involves the participation of numerous immune cells and inflammatory factors. …”
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446
Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway
Published 2025-02-01“…Abstract Acne vulgaris, a prevalent chronic inflammatory skin disorder, is often characterized by hyperactive sebaceous glands and excessive sebum production, presenting a significant therapeutic challenge. …”
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447
Macrophage Activities in Myocardial Infarction and Heart Failure
Published 2020-01-01“…Currently, it has been discovered that the study of macrophages goes far beyond its phagocytotic roles. If researchers in future confirm that macrophages play a vital role in the heart, they can be therapeutically targeted for cardiac healing.…”
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448
Posterior Urethral Valves and Fertility: Insight on Paternity Rates and Seminal Parameters
Published 2025-01-01“…Background: Posterior urethral valves (PUVs) represent the most common cause of male congenital lower urinary tract obstruction, often responsible for renal dysplasia and chronic renal failure. Despite recent improvements in patients’ outcomes thanks to prenatal ultrasound early diagnosis, PUVs can still impact sexual function and fertility. …”
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449
Onychomycosis in Psoriatic Patients with Nail Disorders: Aetiological Agents and Immunosuppressive Therapy
Published 2020-01-01“…Psoriasis and psoriatic arthritis are chronic, relapsing, immune-based diseases. Psoriatic patients may have nail involvement in 50 to 80% of cases, and this may reach 85% in patients with joint disease, in spite of the fact that the relationship between psoriasis and onychomycosis is not well established. …”
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450
Genomic insights into a multidrug-resistant pandoraea apista clinical isolate carrying blaOXA-153 from China
Published 2025-03-01“…Objectives: Pandoraea apista is notable for its multidrug resistance and is frequently identified in patients with cystic fibrosis or other chronic lung diseases, where it contributes to persistent lung infections. …”
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451
Incidence and factors associated with postoperative headache among adult elective surgical patients at the university of gondar comprehensive specialized hospital, northwest Ethiop...
Published 2025-01-01“…Abstract Background Postoperative headache is a medical condition that has a strong association with future recurrence and chronic headache, higher morbidity and mortality, extended hospital stays, poor quality of life and high financial burden. …”
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452
The PROPHECI trial: a phase II, double-blind, placebo-controlled, randomized clinical trial for the treatment of pseudoxanthoma elasticum with oral pyrophosphate
Published 2025-01-01“…It also aims to validate the best markers to include in the design of future trials for the treatment of PXE and other parent diseases. …”
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453
Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature
Published 2025-01-01“…Neuroinflammation is a key factor in the progression of neurodegenerative diseases, driven by the dysregulation of molecular pathways and activation of the brain’s immune system, resulting in the release of pro-inflammatory and oxidative molecules. This chronic inflammation is exacerbated by peripheral leukocyte infiltration into the central nervous system. …”
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454
Gender Differences Are a Leading Factor in 5-Year Survival of Patients with Idiopathic Pulmonary Fibrosis over Antifibrotic Therapy Reduction
Published 2025-01-01“…Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with a median survival of 3–5 years. …”
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455
The prevalence of online food delivery service usage and its association with anthropometric measurements in Muscat, Oman; a cross-sectional study
Published 2025-02-01“…Younger age (P = 0.001), being single (P = 0.012), higher educational attainment (P = 0.001), absence of chronic diseases (P = 0.020),and physical inactivity (P = 0.028) were significant predictors. …”
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456
Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study
Published 2025-03-01“…Abstracts: Background: The global incidence of non-alcoholic fatty liver disease (NAFLD) is rising due to changes in modern lifestyle and dietary habits, making it one of the leading causes of chronic liver disease. NAFLD can progress to more severe liver conditions, imposing significant economic burdens. …”
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457
The validation and cross-cultural adaptation of the PainDETECT questionnaire in osteoarthritis-related pain
Published 2025-01-01“…The PainDETECT Questionnaire has been widely used to identify neuropathic components in chronic pain and has been validated for its reliability and validity across various cultural contexts. …”
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458
Alpha-1 Antitrypsin as a Regulatory Protease Inhibitor Modulating Inflammation and Shaping the Tumor Microenvironment in Cancer
Published 2025-01-01“…This review seeks to bridge the gap in the understanding of AAT between inflammatory diseases and cancer, and to foster deeper investigations into its translational potential in cancer immunotherapy in the future.…”
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459
Moxibustion for Herpes Zoster and Postherpetic Neuralgia: A Meta-Analysis
Published 2021-01-01“…At the same time, more than 9 to 34 percent of patients have postherpetic neuralgia (PHN) present with chronic pain for months or even years. Moxibustion has been used to treat herpes zoster and postherpetic neuralgia for many years; however, there has been no comprehensive study to evaluate the efficacy and safety of moxibustion in the treatment of herpes zoster and postherpetic neuralgia. …”
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460
Combined real-time fMRI and real time fNIRS brain computer interface (BCI): Training of volitional wrist extension after stroke, a case series pilot study.
Published 2021-01-01“…<h4>Objective</h4>Pilot testing of real time functional magnetic resonance imaging (rt-fMRI) and real time functional near infrared spectroscopy (rt-fNIRS) as brain computer interface (BCI) neural feedback systems combined with motor learning for motor recovery in chronic severely impaired stroke survivors.<h4>Approach</h4>We enrolled a four-case series and administered three sequential rt-fMRI and ten rt-fNIRS neural feedback sessions interleaved with motor learning sessions. …”
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