Not “Much Room” in the Heart: A Rare Case of a Massive Intracardiac Candida Mass by Ali Haider Jafry, Sardar Hassan Ijaz, Murtaza Mazhar, Areeba Shahnawaz, Ali Yousif

“…A 51-year-old male on chronic total parenteral nutrition (TPN) because of bowel resection presented with fevers, night sweats, and unintentional weight loss. …”
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Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications by Ahmad Vafaeian, Fateme Rajabi, Nima Rezaei

“…TLRs play a crucial role in delaying barrier repair, promoting Th2-mediated dermatitis, shifting the response toward Th1 in the chronic phase, and contributing to the establishment of the itch-scratch cycle, as well as mediating the effects of UV radiation. …”
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Pathophysiology and Treatment of Psoriasis: From Clinical Practice to Basic Research by Yujie Gao, Tianqi Xu, Yu Wang, Yanjinhui Hu, Shaoping Yin, Zhiguo Qin, Hua Yu

“…Psoriasis, a chronic inflammatory dermatosis, represents a significant clinical challenge due to its complex pathogenesis and the limitations of existing therapeutic strategies. …”
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Differences in hair cortisol to cortisone ratio between depressed and non-depressed adolescent women by Yasmine Zerroug, Marie-France Marin, Elyse Porter-Vignola, Patricia Garel, Catherine M. Herba

“…Hair glucocorticoids are key biological markers of chronic stress. We assessed group differences in hair cortisol and cortisone concentrations, and the cortisol/cortisone ratio between depressed adolescent women and a non-depressed comparison group. …”
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TDP-43 as a potential retinal biomarker for neurodegenerative diseases by Margit Glashutter, Margit Glashutter, Printha Wijesinghe, Joanne A. Matsubara, Joanne A. Matsubara

“…These include amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), Alzheimer’s disease (AD), chronic traumatic encephalopathy (CTE), and others. …”
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The link between hyperuricemia and diabetes: insights from a quantitative analysis of scientific literature by Lili Ma, Jing Wang, Li Ma, Xian Min Wang

“…The reference network from 1987 to September 30, 2024, identified 19 clusters highlighting key research areas in HUA and diabetes, such as metabolic syndrome, uropathology, chronic kidney disease (CKD), and CVD. Exploring pathological mechanisms and pharmacological interventions linked to diabetes concomitant with HUA has emerged as a focal point of research and a burgeoning trend within the field.ConclusionThis study is the first scientometric analysis to synthesize research trends on HUA and diabetes, revealing molecular mechanisms and treatment strategies and providing theoretical insights for future clinical use.…”
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Assessing the quality of CKD care using process quality indicators: A scoping review. by Na Zhou, Chengchuan Chen, Yubei Liu, Zhaolan Yu, Aminu K Bello, Yanhua Chen, Ping Liu

“…<h4>Introduction</h4>Assessing the quality of chronic kidney disease (CKD) management is crucial for optimal care and identifying care gaps. …”
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Physically Active Adults with Low Back Pain do not Demonstrate Altered Deadlift Mechanics: A Novel Application of Myotonometry to Estimate Inter-Muscular Load Sharing by Jared M. McGowen, Stephanie R. Albin, Carrie W. Hoppes, Jeffrey S. Forsse, John Abt, Shane L. Koppenhaver

“…Differences in percent stiffness changes were noted between groups for the deadlift position, however the differences were modest and within measurement error. Future studies should investigate the utility of myotonometry as a method to identify LBP-related impairments that contribute to chronic and/or recurrent low back injury…”
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Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review by Maria Mazzitelli, Federico Nalesso, Alberto Enrico Maraolo, Vincenzo Scaglione, Lucrezia Furian, Annamaria Cattelan

“…Fungal colonization, diabetes mellitus, chronic liver disease, malnutrition, and pre-existing lung conditions should all be acknowledged as possible predisposing risk factors. …”
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Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life by Urszula Religioni, Rocío Barrios-Rodríguez, Pilar Requena, Mariola Borowska, Janusz Ostrowski

“…Adherence to therapy, defined as the extent to which a patient follows prescribed therapeutic recommendations, is a pivotal factor in the effective management of chronic diseases such as diabetes, hypertension, and cardiovascular conditions. …”
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Practical insights for enhancing primary care rehabilitation services in low-resource contexts by Maria Y. Charumbira, Karina Berner, Quinette A. Louw

“…Background: Rehabilitation services are crucial for addressing the growing burden of functioning problems related to chronic conditions in low and middle-income countries. …”
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Temporal changes in hospital readmissions for postpartum hypertension in the US, 2010 to 2019; a serial cross-sectional analysis. by Ashwini Deshpande, Deepti Agnihotri, Alexa I K Campbell, Jerome J Federspiel, Evan R Myers, Osondu Ogbuoji

“…<h4>Conclusion</h4>The increasing postpartum hypertension readmission burden suggests rising future health risks among mothers and a growing cost burden to the U.S. healthcare system. …”
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Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

“…BackgroundAs the life expectancy of people living with human immunodeficiency virus (HIV) (PLWH) has improved, chronic disease burden and polypharmacy have increased in PLWH. …”
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A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study by Lauren Kelenc, Brittany Wiles, Fareha Nishat, Chitra Lalloo, Anya Nair, Craig Eling, Melanie Kirby-Allen, Ewurabena Simpson, Roona Sinha, Richard Ward, William T. Zempsky, Sara Ahola Kohut, Jennifer N. Stinson

“… Abstract Background and objectives: Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. …”
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Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review by Jiajun Xin, Hao Zhang, Yushen Li, Yifei Dai, Xiantao Chen, Jiatong Zou, Rui Wang, Zhihui Liu, Bowei Wang

“…When this balance is disturbed, it can lead to acute and chronic infectious diseases such as dental caries and periodontitis, significantly affecting people’s quality of life. …”
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Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening by Cuili Ma, Hwanwook Seong, Xiaowei Li, Xiao Yu, Shunliang Xu, Yujing Li

“…Therefore, the translational efficiency of the research outcomes in clinical applications was significantly weakened, especially for some complex, chronic, and intractable diseases. For example, the clinical trials for human fragile X syndrome (FXS) solely based on animal models have failed such as mGluR5 antagonists. …”
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The anti-oxidation related bioactive materials for intervertebral disc degeneration regeneration and repair by Yingjie Mai, Siying Wu, Penghui Zhang, Ningning Chen, Jun Wu, Fuxin Wei

“…Abstract:: Intervertebral disc degeneration (IVDD) is a prevalent chronic spinal condition characterized by the deterioration of the intervertebral discs (IVD), leading to structural damage and associated pain. …”
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Polyphenols synergistic drugs to ameliorate non-alcoholic fatty liver disease via signal pathway and gut microbiota: A review by Hongcai Li, Jingjing Liang, Mengzhen Han, Zhenpeng Gao

“…Background: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease with an increasing incidence worldwide. …”
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Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review. by Alina Liebich, Shenglin Zheng, Theresa Schachner, Jacqueline Mair, Mia Jovanova, Falk Müller-Riemenschneider, Tobias Kowatsch

“…<h4>Introduction</h4>Aging is the strongest risk factor for most chronic diseases. The rising burden of an aging population and non-communicable diseases (NCDs), contributes to escalating costs for society. …”
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Community-based culturally tailored education programmes for black adults with cardiovascular disease, diabetes, hypertension and stroke: a systematic review protocol of primary em... by Hardeep Singh, Michelle LA Nelson, Joseph IV Fulton, Oya Pakkal, Elizabeth M Uleryk

“…Introduction Chronic conditions and stroke disproportionately affect black adults in communities all around the world partly due to patterns of systemic racism, disparities in care, and lack of resources. …”
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