Differentiating Gender and Sex in Dental Research: A Narrative Review by Alice Alberti, Benedetta Morandi, Luca Francetti, Silvio Taschieri, Stefano Corbella

“…Their integration, which is still not routinely applied, may be improved in the future by updating editorial guidelines and developing more specific methodological recommendations.…”
Get full text

Fetal Growth Restriction Prediction: How to Move beyond by Debora F. B. Leite, Jose G. Cecatti

“…The actual burden and future burden of the small-for-gestational-age (SGA) babies turn their screening in pregnancy a question of major concern for clinicians and policymakers. …”
Get full text

Hypertensive load predicts recovery of renal function for patients undergoing revascularisation for renal artery stenosis by Ben Edgar, Rob Pearson, Andrew Jackson, Callum Stove, Ram Kasthuri, Keith Hussey, Christian Delles, Colin Geddes, Patrick Mark, Giles Roditi, Linsay McCallum, David B. Kingsmore

“…Refractory hypertension (HTi > 120) was associated with a significant benefit from revascularisation with improved renal function (p = 0.003) and reduced risk of future dialysis (p = 0.001). Renal impairment with no hypertensive response was highly predictive of the need for future dialysis. …”
Get full text

Stunting and Associated Factors among Under-Five-Age Children in West Guji Zone, Oromia, Ethiopia by Eyob Afework, Selamawit Mengesha, Demelash Wachamo

“…It remains a problem of greater magnitude particularly in rural and low-income areas. It reflects chronic nutritional deficiencies and illness that occur during the most critical periods for growth and development in early life. …”
Get full text

Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver by Ľudmila Pašková, Viera Kuncírová, Silvester Poništ, Danica Mihálová, Radomír Nosáľ, Juraj Harmatha, Iveta Hrádková, Tomáš Čavojský, František Bilka, Katarína Šišková, Ingrid Paulíková, Lýdia Bezáková, Katarína Bauerová

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease, leading to progressive destruction of joints and extra-articular tissues, including organs such as liver and spleen. …”
Get full text

Exploring the comorbidity mechanisms between atherosclerosis and hashimoto’s thyroiditis based on microarray and single-cell sequencing analysis by Yirong Ma, Shuguang Wu, Junyu Lai, Qiang Wan, Jingxuan Hu, Yanhong Liu, Ziyi Zhou, Jianguang Wu

“…Abstract Atherosclerosis (AS) is a chronic vascular disease characterized by inflammation of the arterial wall and the formation of cholesterol plaques. …”
Get full text

Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
Get full text

A participatory needs assessment to map the system dynamics of overweight related behaviours of 10-14-year-old adolescents living in an underserved neighbourhood in Amsterdam, the... by Helga Emke, Rabab Chrifou, Coosje Dijkstra, Wilma Waterlander, Karien Stronks, Stef Kremers, Mai Chinapaw, Teatske Altenburg

Get full text

Effectiveness of ‘Tackle Your Tics’, a brief, intensive group-based exposure therapy programme for children with tic disorders: study protocol of a randomised controlled trial by Danielle Cath, Annet Heijerman-Holtgrefe, Chaim Huyser, Cara Verdellen, Jolande van de Griendt, Laura Beljaars, Kees-Jan Kan, Ramón Lindauer, Pieter Hoekstra, Lisbeth Utens

“…Tourette syndrome and chronic tic disorders are prevalent neurodevelopmental disorders, placing considerable burden on youth and their families. …”
Get full text

Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i by Michiyo Tomioka, Kathryn L. Braun, Yan Yan Wu, Kay Holt, Paula Keele, Lori Tsuhako, Johnny Yago

“…Asian or Pacific Islander), to self-report depression as a chronic condition, and to have lower levels of fitness at baseline. …”
Get full text

Azithromycin to prevent acute lower respiratory infections among Australian and New Zealand First Nations and Timorese children (PETAL trial): study protocol for a multicentre, int... by Anne B Chang, Keith Grimwood, Yuejen Zhao, Gabrielle B McCallum, Catherine A Byrnes, Heidi Smith-Vaughan, Peter S Morris, Christine Connors, Adrian Trenholme, Shirley Lawrence, Joshua Francis, Kobi L Schutz, Mark D Chatfield, Nevio Sarmento, Robyn L. Marsh, Emily R Bowden, Nicholas Fancourt, Adriano Vieira, Kim M Hare, Dennis Bonney, Felicity Marwick, Bronwyn Karvonen, Carolyn Maclennan, Milena Santos Lay, Endang Soares da Silva

“…Severe (hospitalised) and recurrent ALRIs in the first years of life are associated with future chronic lung diseases (eg, bronchiectasis) and impaired lung function. …”
Get full text

The Association of COPD Exacerbations with New Onset Type 2 Diabetes among Medicare Patients by Joseph S. Marino, Cynthiya Ruban, Christopher M. Blanchette

“…**Objective:** Chronic obstructive pulmonary disease (COPD) is highly prevalent in the elderly population and typically reduces overall quality of life. …”
Get full text

Correlation of Inflammatory Markers and Disease Severity with Cardiovascular Autonomic Dysfunction in Indian Patients with Rheumatoid Arthritis by Mohan Babu Saminathan, Renuka Sharma, Arun Gogna, Anita Rani, Raj Kapoor

“…Background: RA is an autoimmune disease characterized by chronic systemic inflammation, affecting approximately 1% of the population. …”
Get full text

Functional Brain Plasticity Associated with ACL Injury: A Scoping Review of Current Evidence by T. Neto, T. Sayer, D. Theisen, A. Mierau

“…Anterior cruciate ligament (ACL) injury is a common problem with consequences ranging from chronic joint instability to early development of osteoarthritis. …”
Get full text

Promotion of physical activity-related health competence using digital workplace-based health promotion: a pilot study for office workers by Leonard Oppermann, Marie-Luise Dierks

“…IntroductionEngaging in health-enhancing physical activity (HEPA) can reduce the risk of developing chronic diseases, which is particularly important for office workers with sedentary lifestyles. …”
Get full text

Impact of COVID-19 on Ocular Surface Health: Infection Mechanisms, Immune Modulation, and Inflammatory Responses by Duliurui Huang, Weixia Xuan, Zhijie Li

“…By consolidating current findings, this review aims to guide preventive and therapeutic strategies while identifying directions for future research to mitigate the ocular consequences of COVID-19.…”
Get full text

Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases by Nargish Parvin, Sang Woo Joo, Tapas K. Mandal

“…Autoimmune diseases present complex therapeutic challenges due to their chronic nature, systemic impact, and requirement for precise immunomodulation to avoid adverse side effects. …”
Get full text

Long-term consequences of the Chornobyl disaster for aquatic ecosystems: A retrospective analysis and prognosis by R. Makhinko

“…Special attention was paid to the impact of chronic radiation pollution on biodiversity, productivity, and genetic structure of aquatic populations. …”
Get full text

Adipocytokines in Atherothrombosis: Focus on Platelets and Vascular Smooth Muscle Cells by Giovanni Anfossi, Isabella Russo, Gabriella Doronzo, Alice Pomero, Mariella Trovati

“…The increased vascular risk is related also to peculiar dysfunction in the endocrine activity of adipose tissue responsible of vascular impairment (including endothelial dysfunction), prothrombotic tendency, and low-grade chronic inflammation. In particular, increased synthesis and release of different cytokines, including interleukins and tumor necrosis factor-α (TNF-α), and adipokines—such as leptin—have been reported as associated with future cardiovascular events. …”
Get full text

Metabolic fate of tea polyphenols and their crosstalk with gut microbiota by Meiyan Wang, Jianying Li, Ting Hu, Hui Zhao

“…Moreover, by reshaping microbial composition and associated metabolites, TPs may exert a systemic protection on host metabolism, which contributes to improve certain chronic metabolic disorders. Given that, further understanding of the metabolic fate of TPs and interplay with gut microbiota as well as potential health-promoting effects are of great significance to development and application of tea and their polyphenolic components in the future as dietary supplements and/or functional ingredients in medical foods.…”
Get full text