Survival in patients with CKD 3–5 after 12 months of exercise training – a post-hoc analysis of the RENEXC trial by Sara Denguir, Matthias Hellberg, Martin Almquist, Naomi Clyne

“…Abstract Background Physical performance is low and physical activity declines in people with chronic kidney disease (CKD). Both factors are associated with decreased survival. …”
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State of the Art Review of Wearable Devices for Respiratory Monitoring by Zhiyu Jia, Hannah Huth, Wen Qi Teoh, Sheng Xu, Bradford Wood, Zion Tsz Ho Tse

“…Respiratory frequency and volume are essential physiological signals for diagnosing and managing respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Wearable devices have emerged as a transformative tool for continuous, non-invasive respiratory monitoring and data portals, providing massive real-time data critical for both clinical and home settings. …”
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Natural products targeting ubiquitination to combat kidney fibrosis by Lianhua Li, Xinhui Huang, Yao Chen, Jibin Liu, Yuhang Qiao, Wenyu Fan, Peiqing Zhang, Xiaoming Yan, Ming Chen

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Blue applicability grade index assessment and response surface modelling to synchronous determination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohyd... by Pintu Prajapati, Krutika Patil, Dhrumi Naik, Veera Shakar Pulusu, Anzarul Haque, Mohd Abul Kalam, Shailesh Shah

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Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study by Sam Salek, Samantha Nier, Zack Pemberton-Whiteley, Tatyana Ionova, Giuseppe Ianni, Giovanni Tripepi, Nick York, Nicole Schroeter, Kathryn Huntley, Michael Rynne, Denis Costello, Lidija Pecova, Esther Natalie Oliva

“…BackgroundDisease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.MethodsThis cross-sectional study used the validated Hematological Malignancy Patient Reported Outcomes (HM-PRO) questionnaire to assess the impact of leukemia subtype, age, sex, and years living with the disease on QoL of patients with leukemia.ResultsOverall, 2,628 patients responded: 45.7% had chronic lymphocytic leukemia (CLL), 34.0% had chronic myeloid leukemia (CML), 11.8% had acute myeloid leukemia (AML), and 3.5% had acute lymphoblastic leukemia (ALL). …”
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An Interval Throwing Program for Baseball Pitchers Based upon Workload Data by Michael M. Reinold, Brittany Dowling, Glenn S. Fleisig, Leonard C. Macrina, Kevin E. Wilk, John T. Streepy, James R. Andrews

“… # Hypothesis/Purpose To 1) develop a updated ITP for rehabilitation of modern baseball pitchers based upon biomechanical and throwing workload data, and 2) compare the updated program with a past program to determine differences in chronic workload and acute:chronic workload ratios (ACWR)…”
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Determinants of traditional Korean medicine utilization by individuals with physical disabilities: inference of causal relationships using Korea health panel data by Chihyoung Son, Jong-hyun Kim, Eunkyung Yoon, Eunji Ahn, Minjung Park, Dongsu Kim

“…Conclusions Individuals with physical disabilities accompanying nonfatal chronic musculoskeletal disorders or other chronic conditions frequently utilized TKM services. …”
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Pharmacological Management of Cardiorenal Syndromes by Andrew A. House, Mikko Haapio, Johan Lassus, Rinaldo Bellomo, Claudio Ronco

“…In this paper, an overview of pharmacological management of acute and chronic Cardiorenal Syndromes is presented, and the need for high-quality future studies in this field is highlighted.…”
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The Impact of Cognitive Anxiety and the Rating of Pain on Care Processes in a Vigilance Task: The Important Part Played by Age by Luis Pinel, Miguel A. Perez-Nieto, Marta Redondo, Luis Rodríguez-Rodríguez, Leticia L. Mateos

“…Chronic pain is a serious public health problem that has grown exponentially in recent years, which is why it has received the attention of numerous researchers. …”
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Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing by Gulam Altab, Brian J. Merry, Charles W. Beckett, Priyanka Raina, Inês Lopes, Katarzyna Goljanek-Whysall, João Pedro de Magalhães

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Examining the Obesogenic Attributes of the Family Child Care Home Environment: A Literature Review by Lucine Francis, Lara Shodeinde, Maureen M. Black, Jerilyn Allen

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Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

“…Despite significant progress, challenges remain in translating these findings into clinically viable therapies. Future studies should concentrate on integrated, interdisciplinary methods to reduce chronic neuroinflammation and slowing the progression of neurodegenerative disorders, providing opportunities for revolutionary advances in CNS therapies.…”
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Active ingredients of traditional Chinese medicine inhibit NOD-like receptor protein 3 inflammasome: a novel strategy for preventing and treating heart failure by Ruifang Lin, Ruifang Lin, Yunfeng Yu, Lixin Du, Zehui Ding, Zehui Ding, Ziyan Wang, Ziyan Wang, Jiaming Wei, Jiaming Wei, Zhihua Guo, Zhihua Guo

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Role of Neutrophil Extracellular Traps in Hypertension and Their Impact on Target Organs by Fei Yu, Jianshu Chen, Xiaowei Zhang, Zhengke Ma, Jingtao Wang, Qiang Wu

“…The development and maintenance of EH are caused by endothelial dysfunction, oxidative stress, and chronic inflammation. Neutrophils are involved in both acute and chronic inflammation since they represent the primary line of defense against inflammatory insults once recruited to the inflamed site where they remove harmful impurities. …”
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Low Urbanization but Not Illiteracy was Associated with Poor Medication Adherence among Elderly People in Rural Taiwan by Pei-Jhih Li, Ling-Chiao Liao, Chin-Ju Chuang, Cheng-Ying Hsieh, Yung-Cheng Huang, Li-Yu Chen, Yi-Hsuan Yang, Feng-Jung Yang, Kai-Chieh Chang, Li-Jiuan Shen, Fei-Yuan Hsiao, Yen-Ming Huang, Chih-Cheng Hsu, Shau-Huai Fu, Chin-Kai Chang, Chen-Yu Wang

“…Moreover, age ≥75 years and low urbanization were significantly associated with poor adherence. Future research is warranted to assess the effect of the interventions to improve medication adherence on chronic disease control, disability, and mortality.…”
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Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL by Yue-miao Zhang, Fa-juan Cheng, Xu-jie Zhou, Yuan-yuan Qi, Ping Hou, Ming-hui Zhao, Hong Zhang

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Global Dynamics and Applications of an Epidemiological Model for Hepatitis C Virus Transmission in China by Mingwang Shen, Yanni Xiao, Weike Zhou, Zhen Li

“…An ever-increasing HCV infection is predicted in the near future. Numerical simulations, performed to investigate the potential effect of antiviral treatment, show that increasing the treatment cure rate and enlarging the treatment rate for patients at the chronic stage remain effective in reducing the number of new infections and the equilibrium prevalence. …”
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Should We Test for Helicobacter Pylori before Treating Gastroesophageal Reflux Disease? by Paul Moayyedi

“…It is likely that treating the infection in childhood will prevent pre-malignant changes associated with H pylori from developing in the future. A meta-analysis of four randomized controlled trials suggest that there is a statistically significant impact on healing of chronic gastritis after one year compared with placebo (RR of chronic gastritis: 0.27; 95% CI 0.23 to 0.32). …”
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Physical Activity: Exploring Views of Older Russian-Speaking Slavic Immigrants by Janet Purath, Catherine Van Son, Cynthia F. Corbett

“…Participants suggested community walking groups and church-supported programs as useful methods to promote physical activity. Future research includes developing culturally appropriate interventions that utilize physical activity to prevent and manage chronic illness with ethnic minority older adults.…”
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Research Progress on the GIP/GLP-1 Receptor Coagonist Tirzepatide, a Rising Star in Type 2 Diabetes by Zijun Ma, Kaiqin Jin, Mengmeng Yue, Xin Chen, Jun Chen

“…Type 2 diabetes mellitus (T2DM) is a chronic progressive metabolic disease that has become a growing health problem worldwide, and the dangers of hyperglycemia and its chronic complications have long been considered a goal of diabetes treatment. …”
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