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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production
Published 2025-02-01“…ELISA was employed to investigate the generation of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), while qRT-PCR was utilized to analyze the mRNA expressions of TNF-α, IL-6, inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2). …”
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Poor Glycemic Control in Carbapenem-Resistant Klebsiella pneumoniae Infections: Impact on Epidemiological Features, Mortality Risks, and Polymyxin Resistance
Published 2025-02-01“…Antibiotic sensitivity, capsular serotypes, and virulence genes were tested of the strains. Three clinically isolated CRKP strains were used to investigate the effect of glucose on bacterial capsule synthesis and the impact on bacterial resistance to polymyxin and serum killing.Results: Patients with poor glycemic control experienced more severe infections and had a higher likelihood of chronic kidney disease (CKD) and acute renal insufficiency compared to those with good glycemic control. …”
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Chemical composition and glucose uptake effect on 3T3-L1 adipocytes of Ligustrum lucidum Ait. flowers
Published 2020-06-01“…Ligustri lucidi Fructus is a traditional Chinese medicine and possesses various bioactivities, including hypoglycemic effect. …”
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Ginsenosides Rg1, Rb1 and rare ginsenosides: Promising candidate agents for Parkinson's disease and Alzheimer's disease and network pharmacology analysis
Published 2025-02-01“…Ginseng has been commonly used as a traditional Chinese medicine in Asian countries for thousands of years. …”
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Genome-Wide Genomic Analysis and Evolutionary Insights into Bovine Coronavirus Strains in Southwest China
Published 2024-12-01“…This study aimed to fill this gap by isolating three BCoV strains from this region and sequencing their whole genomes. …”
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Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan...
Published 2025-01-01“…Next-generation sequencing and phylogenetic analysis revealed that the detected virus was a variant of GPV, globally named novel GPV (NGPV), and closely related to Chinese NGPV isolates. To our knowledge, the current study is pioneering to address the immunopathological impact of NGPV among naturally infected ducks confirmed with full genome sequencing and immunohistochemical identification worldwide.…”
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Population genetic analysis of clinical Mycobacterium abscessus complex strains in China
Published 2025-01-01“…BackgroundTo explore the genetic characteristics of the Mycobacterium abscessus complex (MABC) population in China, given its rising clinical importance among nontuberculous mycobacteria.MethodsWe conducted population genetic analyses on 360 MABC genomes from China, focusing on core genome multilocus sequence typing (cgMLST), pan-genome characterization, population genetics, and antimicrobial resistance gene profiling.ResultsOur analysis identified 273 M. abscessus subsp. abscessus (MabA) and 87 M. abscessus subsp. massiliense (MabM) isolates, uncovering 68 sequence types (STs), with ST5 being the most common. cgMLST classified 33.3% of isolates into six dominant circulating clones (DCCs) and 49.4% into 59 genomic clusters at a threshold of 25 different alleles, including 18 international clusters linking Chinese isolates with seven other countries. …”
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A distinct double-ring LH1–LH2 photocomplex from an extremophilic phototroph
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Fine-mapping of PmHHM, a broad-spectrum allele from a wheat landrace conferring both seedling and adult resistance to powdery mildew
Published 2025-02-01“…To map its PM resitance gene, bulked segregant analysis, molecular mapping and comparative genomic analysis were also used in the present study.ResultsHHM shows remarkable adult resistance in the field and is nearly immune to all 25 Bgt isolates used in seedling tests, making it an excellent source of PM resistance. …”
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Special issue: Proceedings of the 15th ISIC - The Information Behaviour Conference, Aalborg, Denmark, August 26-29, 2024
Published 2024-06-01“…Hands, Katarina Švab, Tanja Merčun Using progress logs to research the information behaviour of higher education students in prison Isabel Virgo Savolainen’s everyday information practices: concept and development Xinyue Wang Digital stress among Chinese adolescents: a focus group study Zhang Wen, Chen Yifan, Cao Gaohui Creating, using, and sharing embodied information in the ultrarunning community on Instagram Laura Williams, Andrew Cox, Andrea Jimenez Isolated, individualised, and immobilised: information behaviour in the context of academic casualisation Rebekah Willson, Owen Stewart-Robertson, Heidi Julien, Lisa M. …”
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miR-317 regulates the proliferation and apoptosis of duck follicle granulosa cells by targeting VIPR1
Published 2025-01-01Get full text
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Observations of Microlensed Images with Dual-field Interferometry: On-sky Demonstration and Prospects
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