Vaginal Microbiota Diversity of Patients with Embryonic Miscarriage by Using 16S rDNA High-Throughput Sequencing by Linfen Xu, Lingna Huang, Chengying Lian, Huili Xue, Yanfang Lu, Xiujuan Chen, Yong Xia

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The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review by Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G

“…Yanyun Li,1 Changying Li,2 Junzi Fan,3 Yutong Liu,1 Yincong Xu,4 Guowei Pang1 1School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 2School of Ophthalmology and optometry, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 3School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 4College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of ChinaCorrespondence: Yincong Xu; Guowei Pang, Email onion521@sina.com; pgw@sdutcm.edu.cnBackground: Cancer immunotherapy is an advanced therapeutic approach that harnesses the body’s immune system to target and eliminate tumor cells. …”
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The Investigation of the Relationship Between Individual Pain Perception, Brain Electrical Activity, and Facial Expression Based on Combined EEG and Facial EMG Analysis by Ma C, Wang C, Zhu D, Chen M, Zhang M, He J

“…Chaozong Ma,1,2,* Chenxi Wang,3,* Dan Zhu,1 Mingfang Chen,1 Ming Zhang,1,4 Juan He1 1Department of Rehabilitation Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Military Medical Psychology School, Fourth Military Medical University, Xi’an, People’s Republic of China; 3Center for Brain Imaging, School of Life Science and Technology, Xidian University, Xi’an, People’s Republic of China; 4Department of Medical Imaging, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Zhang; Juan He, Email zhangming01@mail.xjtu.edu.cn; hejuan198553@126.comPurpose: Pain is a multidimensional, unpleasant emotional and sensory experience, and accurately assessing its intensity is crucial for effective management. …”
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Exploring the Causal Relationship Between Frailty and Chronic Obstructive Pulmonary Disease: Insights From Bidirectional Mendelian Randomization and Mediation Analysis by Cheng Z, Wu J, Xu C, Yan X

“…Zewen Cheng,1 Jian Wu,1 Chun Xu,2 Xiaokun Yan1 1Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou, Jiangsu, 215000, People’s Republic of China; 2Department of Cardio-Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215000, People’s Republic of ChinaCorrespondence: Xiaokun Yan, Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou, Jiangsu, 215000, People’s Republic of China, Email yanxk2008@126.comBackground: Observational studies have underscored a robust association between frailty and chronic obstructive pulmonary disease (COPD), yet the causality remains equivocal.Methods: This study employed bidirectional two-sample Mendelian randomization (MR) analysis. …”
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Adaptive anti-jamming scheme based on meta-surface antenna by GUO Yuze, JIN Liang, XU Xiaoming, MA Keming, PEI Chen

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Utilizing a Wireless Radar Framework in Combination With Deep Learning Approaches to Evaluate Obstructive Sleep Apnea Severity in Home-Setting Environments by Lee KT, Liu WT, Lin YC, Chen Z, Ho YH, Huang YW, Tsai ZL, Hsu CW, Yeh SM, Lin HY, Majumdar A, Chen YL, Kuan YC, Lee KY, Feng PH, Chen KY, Kang JH, Lee HC, Ho SC, Tsai CY

“…Kun-Ta Lee,1 Wen-Te Liu,2– 6 Yi-Chih Lin,3,7 Zhihe Chen,8 Yu-Hsuan Ho,9 Yu-Wen Huang,9 Zong-Lin Tsai,9 Chih-Wei Hsu,9 Shang-Min Yeh,9 Hsiao Yi Lin,9 Arnab Majumdar,8 Yen-Ling Chen,10 Yi-Chun Kuan,3,11– 13 Kang-Yun Lee,4,6 Po-Hao Feng,4,6 Kuan-Yuan Chen,4,6 Jiunn-Horng Kang,5,6,14– 16 Hsin-Chien Lee,17 Shu-Chuan Ho,2,6,* Cheng-Yu Tsai2– 6,16,18,* 1Respiratory Therapy Room, Division of Pulmonary Medicine, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; 2School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan; 3Sleep Center, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; 4Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; 5Research Center of Artificial Intelligence in Medicine, Taipei Medical University, Taipei, Taiwan; 6Research Center of Thoracic Medicine, Taipei Medical University, Taipei, Taiwan; 7Department of Otolaryngology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; 8Department of Civil and Environmental Engineering, Imperial College London, London, UK; 9Advanced Technology Lab, Wistron Corporation, Taipei, Taiwan; 10Institute of Biomedical Informatics, National Yang Ming Chiao Tung University, Taipei, Taiwan; 11Department of Neurology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan; 12Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 13Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan; 14Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan; 15Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan; 16Professional Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 17Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan; 18School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan*These authors contributed equally to this workCorrespondence: Cheng-Yu Tsai, School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, 250 Wuxing Street, Taipei, 11031, Taiwan, Tel +886-2-2736-1661, Fax +886-2-2739-1143, Email b117101018@tmu.edu.tw Shu-Chuan Ho, School of Respiratory Therapy, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei, 11031, Taiwan, Tel +886-2-2736-1661, Fax +886-2-2739-1143, Email shu-chuan@tmu.edu.twObjective: Common examinations for diagnosing obstructive sleep apnea (OSA) are polysomnography (PSG) and home sleep apnea testing (HSAT). …”
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Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…Recent research shows that machine-learning approaches enable the integration of geochemical data and the successful identification and separation of geochemical anomalies associated with mineralization that may be overlooked using non-machine learning methods (Tukey, 1977; Cheng, 2006; Cheng et al., 2010). In this study, the combined method of autoencoder network with the fractal concentration-area method was applied to identify geochemical anomalies in the Hashtjin area (Ardabil province), NW Iran. …”
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Development and Validation of a Nosocomial Infection Nomogram Model in the NICU: A Novel and Nurse-Led Way to Prediction in Preterm Infants by Shang Y, Chen L, Hu X, Zhang K, Cheng Q, Shui X, Deng Z

“…Yanyan Shang,* Ling Chen,* Xindie Hu, Keqian Zhang, Qian Cheng, Xiaoyu Shui, Zhiyue Deng Department of Neonatology, Renmin Hospital of Wuhan University, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiyue Deng; Xiaoyu Shui, Department of Neonatology, Renmin Hospital of Wuhan University, Wuchang District, Jiefang Road, No. 99, Wuhan, Hubei, 430060, People’s Republic of China, Tel +86 18086403090, Email 2015302180361@whu.edu.cn; 15926276672@163.comPurpose: Nosocomial infections (NI) are a leading cause of mortality in preterm infants in the Neonatal Intensive Care Unit (NICU). …”
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Investigating Brain Structure and Functional Alterations in the Transition from Acute to Chronic Neck Pain: A Resting-State fMRI Study by Gao Z, Cui MJ, Wang HJ, Zhang J, Xu C, Ji LX

“…Zhen Gao,1,* Meng-Jie Cui,2,* Hai-Jun Wang,2 Jing Zhang,3 Cheng Xu,4 Lai-Xi Ji2 1Experimental Management Center, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 2Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 3Acupuncture and Moxibustion Department II, Affiliated Hospital of Shanxi University of Traditional Chinese Medicine, Taiyuan, Shanxi, 030024, People’s Republic of China; 4Radiology Department, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lai-Xi Ji, Second Clinical Medical College, Shanxi University of Traditional Chinese Medicine, Jinci Road Section 1, No. 89, Taiyuan, Shanxi, 030024, People’s Republic of China, Email jlx@sxtcm.edu.cnPurpose: The objective of this research is to delve into the central pathological mechanisms involved in the transformation from acute to chronic pain.Patients and Methods: This study enrolled 86 individuals with acute neck pain and 89 with chronic neck pain. …”
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Deep Learning and Radiomics in Triple-Negative Breast Cancer: Predicting Long-Term Prognosis and Clinical Outcomes by Cheng C, Wang Y, Zhao J, Wu D, Li H, Zhao H

“…Chen Cheng,1,* Yan Wang,2,3,* Jine Zhao,4,* Di Wu,1 Honge Li,5 Hongyan Zhao1 1Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, Lianyungang, 222004, People’s Republic of China; 2Department of Ultrasound, Lianyungang Municipal Oriental Hospital, Lianyungang, 222046, People’s Republic of China; 3Department of Ultrasound, Xuzhou Medical University Affiliated Hospital, Lianyungang, Jiangsu, 222061, People’s Republic of China; 4Department of Ultrasound, Donghai County People’s Hospital, Lianyungang, Jiangsu, 222300, People’s Republic of China; 5Department of Ultrasound, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu, 222061, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongyan Zhao, Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, No. 160, Chaoyang Middle Road, Haizhou District, Lianyungang, 222004, People’s Republic of China, Tel +86 0518-85574003, Email zhaohongyanzhy01@126.comAbstract: Triple-negative breast cancer (TNBC) is a unique breast cancer subtype characterized by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression in tumor cells. …”
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The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for... by Huang Z, Liang X, Luo Y, Fang Z, Xu M, Xu Y, Cheng S, Li L

“…Ziling Huang,1 Xin Liang,1 Yuheng Luo,1 Zhou Fang,2 Ming Xu,1 Yinqin Xu,1 Shan Cheng,3 Lihong Li1 1Department of Acupuncture and Moxibustion, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 2Department of Orthopedics, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 3Ultrasound Center, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of ChinaCorrespondence: Lihong Li, Email 1109718711@qq.comBackground: Plantar fasciitis is a common cause of heel pain, often associated with a higher rate of low back pain. …”
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Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis by Yang C, Lei C, Jing G, Xia Y, Zhou H, Wu D, Zuo J, Gong H, Wang X, Dong Y, Aidebaike D, Wu X, Song X

“…Cheng Yang,1,* Chuntian Lei,1,* Guoqing Jing,1 Yun Xia,1 Huimin Zhou,1 Die Wu,1 Jing Zuo,1 Hailong Gong,1 Xing Wang,1 Yingyue Dong,1 Delida Aidebaike,1 Xiaojing Wu,2 Xuemin Song1 1Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, 430062, People’s Republic of China; 2Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaojing Wu; Xuemin Song, Email RM000851@whu.edu.cn; xueminsong@whu.edu.cnBackground: Sepsis, as a clinically critical disease, usually induces coagulation disorders. …”
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Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer by Wang S, Ma C, Ren Z, Zhang Y, Hao K, Liu C, Xu L, He S, Zhang J

“…Shunda Wang,1,* Cuidie Ma,2,* Zhihua Ren,3,* Yufei Zhang,2 Kun Hao,4 Chengxiu Liu,4 Lida Xu,4 Shun He,5 Jianwei Zhang1 1Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China; 3Department of General Surgery, Qilu Hospital Fo Shandong University, Jinan, 250012, People’s Republic of China; 4Beijing Hotgen Biotech Co., Ltd, Beijing, 102600, People’s Republic of China; 5Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shun He, Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China, Email heshuns@126.com Jianwei Zhang, Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China, Email panchutong@163.comIntroduction: Early diagnosis is crucial for improving the prognosis of patients with gastric cancer (GC). …”
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Predictive Laboratory Markers for Gastrointestinal Complications in Children with Henoch-Schönlein Purpura by Guo Q, Xia S, Ding Y, Liu F

“…Qin Guo,1,* Shengying Xia,2,* Yan Ding,3 Fan Liu3 1Department of General Surgery, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, People’s Republic of China; 2Department of Emergency and Critical Care Center, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science &Technology, Wuhan, 430016, People’s Republic of China; 3Department of Rheumatology and Immunology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science &Technology, Wuhan, 430016, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fan Liu; Yan Ding, Department of Rheumatology and Immunology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science &Technology, No. 100 hong Kong Road, Jiang’an District, Wuhan, 430016, People’s Republic of China, Tel +86 02782824022, Email LFwhetyy@outlook.com; DYwhetyy@outlook.comBackground: Henoch-Schönlein Purpura (HSP) is a common systemic vasculitis in children that often involves the gastrointestinal system (GIS). …”
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Research on（t，k）-diagnosability for augmented cube network under the comparison model by Jia-rong LIANG, Miao-jiang CHEN

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A Case Study of Using Numerical Analysis to Assess the Slope Stability of National Freeways in Northern Taiwan by Hao-Wei Chiu, Yi-Hao Tsai, Chao-Wei Tang, Chih-Yu Chu, Shong-Loong Chen

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Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment by Lee YH, Huang CY

“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
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Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy by Kun Wang, Yingying Zhang, Zhaoming Su, Bei Wang, Yuanyang Zhou, Xiaochu Tong, Chengying Xie, Xiaomin Luo, Sulin Zhang, Mingyue Zheng

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Oxidative potential determines the oxidative stress and ferroptotic toxicity of airborne particulate matter on pulmonary epithelial cells by Bingxue Nie, Daoqiang Zhang, Xin Liu, Chengying Lei, Zhiruo Li, Nan Zhang, Shuping Zhang, Yiju Wei, Jie Zhang

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Predictive Value of Albumin to Fibrinogen Ratio and CALLY Index for Diagnosis of Ulcerative Colitis and Mucosal Healing After Vedolizumab Treatment by Su K, Xiao S, Wang M, Wang K, Fan Q, Sha S, Cheng Y, Liu X, Shi H

“…Kairong Su,1,* Sinan Xiao,1,* Mei Wang,2 Kairuo Wang,1 Qing Fan,1 Sumei Sha,1 Yongli Cheng,3 Xin Liu,1 Haitao Shi1 1Department of Gastroenterology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Gastroenterology, Xi’an International Medical Center Hospital, Xi’an, Shaanxi, People’s Republic of China; 3Department of Gastroenterology, Xi’an Chang’an District Hospital, Xi’an, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Liu, Department of Gastroenterology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, Email docliuxin126@xjtu.edu.cn Haitao Shi, Department of Gastroenterology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China, Email shihaitao7@xjtu.edu.cnPurpose: The albumin to fibrinogen ratio (AFR), a biomarker associated with inflammatory, nutritional, and coagulation status, and the CALLY index, a biomarker combining C-reactive protein, albumin, and lymphocyte count, have been suggested to correlate with prognosis in a variety of diseases in previous studies; however, studies of these two markers in ulcerative colitis (UC) are lacking. …”
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