Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties by Kato Bredael, Silke Geurs, Dorien Clarisse, Karolien De Bosscher, Matthias D’hooghe

“…Lead optimization represents the tedious process of fine-tuning lead compounds from biologically active hits to suitable drug candidates for clinical trials. By chemically modifying a hit structure, an improved compound can be obtained in terms of activity, selectivity, and pharmacokinetic ADME (absorption, distribution, metabolism, and excretion) properties. …”
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Nitrogen and Sulphur Relations in Effecting Yield and Quality of Cereals and Oilseed Crops by B.K. Nad, T.J. Purakayastha, D.V. Singh

“…Nitrogen and sulphur, both vital structural elements, are especially needed for the synthesis of proteins and oils. …”
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Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro by Fenghua Zhou, Yan Shi, Sujun Tan, Xiaoli Wang, Weicheng Yuan, Shuqi Tao, Ping Xiang, Bin Cong, Chunling Ma, Di Wen

“…Due to the structural diversity and rapid prevalence of synthetic cannabinoids (SCs) in the market, the information linking the chemical structure of SCs to their toxicity remains scant, despite emerging in the 1970s. …”
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Drug allergy by Samira Jeimy, Tiffany Wong, Moshe Ben-Shoshan, Ana Maria Copaescu, Ghislaine A. C. Isabwe, Anne K. Ellis

“…When available, alternative medications with unrelated chemical structures should be substituted. Cross-reactivity among drugs should also be taken into consideration when choosing alternative agents. …”
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Experimental Characterization of C–C Composite Destruction Under Impact of High Thermal Flux in Atmosphere and Hypersonic Airflow by Ryan Bencivengo, Alin Ilie Stoica, Sergey B. Leonov, Richard Gulotty

“…Hypersonic flight in the atmosphere is associated with high thermal flux impacting the vehicle surface. …”
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Progress in devulcanization of waste tire rubber: Upcycling towards a circular economy by Zaheer ul Haq, Teng Ren, Xinyan Yue, Krzysztof Formela, Denis Rodrigue, Xavier Colom Fajula, Tony McNally, Dong Dawei, Yong Zhang, Shifeng Wang

“…This review comprehensively assesses the current state-of-the-art techniques for tire rubber devulcanization, including physical, chemical and biological methods. It explores the intricacies of ground tire rubber as a starting material, structural evolution of ground tire rubber during the devulcanization process and the associated challenges in achieving efficient devulcanization while retaining desirable mechanical properties. …”
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Risk Evaluation of Pyrolyzed Biochar from Multiple Wastes by Shem M. Ndirangu, Yanyan Liu, Kai Xu, Shaoxian Song

“…Feedstock properties and the resultant biochar produced at different pyrolysis process influence their chemical, physical, and structural properties, which are vital in understanding the functionality of biochar. …”
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Effects of H^{−} low beam irradiation and high field pulsing tests in different metals by C. Serafim, S. Calatroni, F. Djurabekova, R. Peacock, V. Bjelland, A. T. Perez-Fontenla, W. Wuensch, A. Grudiev, S. Sgobba, A. Lombardi, E. Sargsyan

“…This work studies the suitability of a set of different materials for manufacturing more efficient and durable radio-frequency quadrupole (RFQ) structures compared to that currently used in many linear particle accelerators, traditionally made out of copper. …”
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Modeling of CO2 solubility and partial pressure in blended diisopropanolamine and 2-amino-2-methylpropanol solutions via response surface methodology and artificial neural network by Zohreh Khoshraftar

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Study of defect formation mechanisms in Li2ZrO3/MgLi2ZrO4 ceramics using EPR spectroscopy by Dmitriy I. Shlimas, Ainagul A. Khametova, Artem L. Kozlovskiy, Maxim V. Zdorovets

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Whole-rock geochemistry and crystal chemistry of apatite at intrusive suites of the Qeynarjeh-Angouran district (west of Zanjan): an approach to the identification of skarn-causati... by Afsoon Dastour, Ebrahim Tale Fazel, Ashraf Torkian

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New insights into the N-glycomes of Dictyostelium species by Alba Hykollari, Daniel Malzl, Chunsheng Jin, Carina Eschenbach, Kristína Kianičková, Iain B.H. Wilson, Katharina Paschinger

“…The detailed glycomic analysis of their fruiting bodies was based on isomeric separation of the glycan structures by HPLC, followed by mass spectrometry in combination with enzymatic digests and chemical treatments. …”
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Deciphering Design of Aggregation‐Induced Emission Materials by Data Interpretation by Junyi Gong, Ziwei Deng, Huilin Xie, Zijie Qiu, Zheng Zhao, Ben Zhong Tang

“…Abstract This work presents a novel methodology for elucidating the characteristics of aggregation‐induced emission (AIE) systems through the application of data science techniques. A new set of chemical fingerprints specifically tailored to the photophysics of AIE systems is developed. …”
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Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020 by Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie

“…Natural products, endowed with unique chemical structures and diverse biological activities through long-term natural selection, have emerged as a vital resource for discovering novel RAS-targeted therapeutic drugs. …”
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Global Assessment of Emerging Contaminant Removal in Wastewater Treatment Plants: <i>In Silico</i> Hazard Screening and Risk Evaluation by Arianna Sgariboldi, Elena Posté, Nicola Chirico, Alessandro Sangion, Marco Evangelista, Cristiana Morosini, Andrea Re, Vincenzo Torretta, Ester Papa

“…Finally, chemicals were prioritized by combining values of RE and QSAR predictions for multiple properties. …”
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The Kerbernez long-term experiment: A dataset on crop yield and soil organic matter evolution in forage crop rotations and permanent grasslands in a temperate oceanic climateData G... by Anne-Isabelle Graux, Alice Cadéro, Fabien Ferchaud, Françoise Vertès

“…The dataset also includes characterisation of soil structural stability, particle-size soil organic matter fractions and potential soil carbon and nitrogen mineralisation at the end of the trial. …”
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Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives by Bhaskar Das, Bharat Gopalrao Somkuwar, Sushil Kumar Chaudhary, Evanylla Kharlyngdoh, Careen Liza Pakyntein, Kishor Basor, Jitendra Kumar Shukla, Pardeep Kumar Bhardwaj, Pulok Kumar Mukherjee

“…These medicinal plants are an excellent source of chemically diverse biologically active phytometabolites. …”
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Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023) by Hesham R. El-Seedi, Mohamed S. Refaey, Nizar Elias, Mohamed F. El-Mallah, Faisal M. K. Albaqami, Ismail Dergaa, Ming Du, Mohamed F. Salem, Haroon Elrasheid Tahir, Maria Dagliaa, Nermeen Yosri, Hongcheng Zhang, Awg H. El-Seedi, Zhiming Guo, Shaden A. M. Khalifa

“…Additionally, the review highlights the innovative strategies employed in the isolation, structural elucidation, and chemical modification of marine natural products to enhance their potency, selectivity, and pharmacological properties. …”
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Pigmented Maize (Zea mays L.) Contains Anthocyanins with Potential Therapeutic Action Against Oxidative Stress - A Review by Jesús Miguel Magaña Cerino, Héctor Arturo Peniche Pavía, Axel Tiessen, Carmen Magdalena Gurrola Díaz

“…Here, we describe the occurrence of anthocyanins from pigmented maize and their chemical structures. Furthermore, the biosynthesis, bioavailability, and stability are also summarized. …”
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Human hair biochar to remove malachite green dye and bisphenol-A contamination by M. Kamaraj, P. Kamali, R. Kaviya, K. Abishek, B. Navinkumar, T.G. Nithya, L.S. Wong, J. Aravind

“…BACKGROUND AND OBJECTIVES: Exposure to endocrine-disrupting chemicals and organic dye pollution is associated with an increased risk of toxicity, hazard, and cancer due to their widespread use. …”
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