Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…Neuropathological alterations of MEF2C-KD mice with mitochondrial dysfunction and motor neuronal damage were observed by confocal microscopy and transmission electron microscope (TEM). Behavioral changes of mice were examined through longitudinal study by tail suspension, inverted grid test and automated gait analysis. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…Furthermore, the immunogenicity of ΔmcpC was analyzed in mice by measuring specific IgG and SIgA antibody levels, lymphocyte proliferation, cytokine expression, and the protective efficacy of ΔmcpC vaccination.ResultsCompared to the wild-type strain, ΔmcpC exhibited no significant changes in biofilm formation or adhesion to Caco-2 cells. …”
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Enhancing anthropometric proficiency: Effect of a structured training program on skills of Anganwadi workers in rural areas of Raebareli District, Uttar Pradesh by Mukesh Shukla, Abhay Singh, Sourabh Paul, Mritunjay Kumar, Ravinder Singh Bedi

“…Anthropometric skills help Anganwadi workers assess any changes or deterioration in the normal growth of children. …”
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Akin Ogundiran: The Historian and Archaeologist of Yoruba-Atlantic becomes Chancellor Professor at the University of North Carolina at Charlotte by Toyin Falola

“…Ogundiran has to grapple not only with the meaning of local history, but also with the definition of the world in which the local is situated against the background of rapidly changing events. And if, as he treats the local, he engages in issues around production and trade—as all his objects indicate—he is forced to engage in the understanding of how society relates to nature: that is, how humans ultimately relate to their environments, using and destroying them at the same time, and sometimes renewing them as well. …”
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Impact of health education on knowledge retention among caregivers of hypertensive patients: A prospective cross-sectional study in rural Malawi. by Chikondi Maluwa, Sitalire Kapira, Hataichanok Chuljerm, Wason Parklak, Kanokwan Kulprachakarn

“…In low- and middle-income countries, like Malawi, the burden of hypertension is escalating due to inadequate healthcare resources and lifestyle changes. Family members often become primary caregivers, playing a crucial role in managing hypertension through support and adherence to treatment. …”
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Assessment of derangement in biochemical profile in primary open angle glaucoma patients presenting at a tertiary care hospital by Fatima Tuz Zuhra, Mehnaz Khattak, Sana Nadeem, Noreen Atzaz, Attika Khalid, Sami Saeed

“… Objective: To assess the changes in high sensitivity C Reactive protein (hs-CRP), serum cholesterol, uric acid, creatinine, bilirubin and ALT in patients of primary open angle glaucoma. …”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

“…Primary outcomes included changes in inflammatory markers (white blood cell count, C-reactive protein, and procalcitonin), imaging outcomes (resolution of pleural effusion, pulmonary inflammation, and the incidence of pleural thickening at three months), pulmonary function assessed by forced vital capacity (FVC), and in-hospital mortality. …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Methods Single-cell RNA sequencing was conducted on the skin tissues of NIID patients to assess changes in the expression of genes involved in inflammatory pathways. …”
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Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase by Valeriya Bezkorovayna, Brooke K. Hayes, Francesca N. Gillett, Amy Wright, David I. Roper, Marina Harper, Sheena McGowan, John D. Boyce

“…This study provides molecular insight into how the T6SS allows A. baumannii strains to gain dominance in polymicrobial communities and thus improve their chances of survival and transmission.IMPORTANCEWe have shown that the Acinetobacter baumannii T6SS effector Tae17 is a modular, bifunctional, peptidoglycan-degrading enzyme that has both lytic transglycosylase and amidase activities. …”
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El uso de acaricidas para el control de Rhipicephalus (Boophilus) microplus (Canestrini) (Acari: Ixodidae) en la Argentina by A.A. Guglielmone, M.E Castelli, A.J. Mangold, D.H. Aguirre, E. Alcaraz, M.M. Cafrune, B. Cetrá, C.A. Luciani, V.H. Suárez

“…Ello alerta sobre las mayores chances para el desarrollo de garrapatas resistentes a la formamidina en esas zonas. …”
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Implementasi Algoritma AES 256 CBC, BASE 64, Dan SHA 256 dalam Pengamanan dan Validasi Data Ujian Online by Ferzha Putra Utama, Gusman Wijaya, Ruvita Faurina, Arie Vatresia

“…Although online exams can be held anywhere and anytime, unfortunately, many violations and fraud exist, such as leaking exam questions, spreading answer keys illegally, and changing exam result data. One solution for maintaining the integrity of online-based exam results is to encrypt exam data with cryptographic methods. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…Over the study period (13 years), the structure of mortality from DD has not changed significantly among the region’s population. …”
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The effects of circuit hydraulic weight interval training on body composition and progression of resistance in recreationally exercising pre- and postmenopausal women: an 18-week q... by Małgorzata Socha, Paulina Ćwieląg, Waldemar Andrzejewski

“…No significant differences were found in the controls.ConclusionCHWIT is an effective form of training, improving body composition and physical functions in inactive pre- and postmenopausal women. Changes in the muscle component require a longer intervention of physical effort in women after menopause.…”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…While previous studies on canine DLBCL (cDLBCL) have significantly advanced our understanding of the disease, the majority of this research has relied on whole-exome sequencing, which is limited in its ability to detect copy number aberrations and other genomic changes beyond coding regions. Furthermore, many of these studies lack sufficient clinical follow-up data, making it difficult to draw meaningful associations between genetic variants and patient outcomes. …”
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Proprioceptive Reweighting and Postural Control are Impaired Among Elite Athletes Following Anterior Cruciate Ligament Reconstruction by Benoit Attalin, Telma Sagnard, Eric Laboute, Nicolas Forestier, Olivier Rémy-Néris, Brice Picot

“…This reflects an inability to adapt proprioceptive weighting when balance conditions are changing and suboptimal postural strategies. # Level of Evidence 3b…”
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Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre... by A. D. Kaprin, N. S. Sergeeva, S. S. Pirogov, I. I. Alentov, O. К. Yutsevich, V. I. Ryabtseva, G. F. Minibaeva, N. V. Marshutina, T. А. Karmakova

“…“GastroPanel®” confirmed its high significance in identifying H. pylori infection and precancerous atrophic changes in the gastric mucosa. Regarding the occupational risks of infection among medical workers, we consider it advisable to conduct such screening without selecting an asymptomatic population.…”
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Performance of some civil engineering structures on Odukpani clay shale, Southeastern Nigeria by Abidemi Olujide Ilori, Anthony Michael George, Ini Christopher Umoh, Ediomo O. Eyakndue, Ubong Udoette Ukpekpe

“…Results indicate the near the surface horizon which serves as the foundation for highway pavement is composed of soil materials that are highly permeable, dispersive, collapsible, easily eroded as indicated by low Slake Durability Index with values between 6.9 and 51.42%; properties which are all dependent on changes in water content. Whereas at depth, the same soil sequence but stable as permeability to water is very low, hence the stability of bridge foundations in them.…”
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From Peril to Protection: an evaluation of regulations impacting eScooter injuries by Leslie M Kobayashi, Todd W Costantini, Jay J Doucet, Jarrett E Santorelli, Laura N Haines, Kendra M Black

“…This demonstrates the importance of advocacy efforts in response to changes in injury patterns and mechanisms of injury. …”
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Effects of Brackish Water with Different Sodium-Potassium Ratios on Soil Water-Salt Characteristics and Winter Wheat Growth by GAO Weiqiang, ZHANG Tibin, TONG Jiankang, LIU Zhenyuan, LIANG Qing, KUANG Yuxin, CHENG Yu, FENG Hao

“…[Conclusion] In summary, irrigation using 4 dS/m brackish water changed the original water-salt characteristics of the soil, caused salts to accumulate in the soil and promoted winter wheat growth in the short term. …”
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