Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
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In Vivo Tracking of Systemically Administered Allogeneic Bone Marrow Mesenchymal Stem Cells in Normal Rats through Bioluminescence Imaging by Juan Cao, Shike Hou, Hui Ding, Ziquan Liu, Meijuan Song, Xiaojing Qin, Xue Wang, Mengyang Yu, Zhiguang Sun, Jinyang Liu, Shuli Sun, Peixin Xiao, Qi Lv, Haojun Fan

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Computed tomography-guided microwave ablation for right middle lobe pulmonary nodules: a retrospective, single-center, case-control study by Yanting Hu, Guoliang Xue, Xinyu Liang, Zhichao Li, Nan Wang, Pikun Cao, Gang Wang, Haitao Zhang, Xiaohuan Zheng, Aiguang Wang, Wenhua Zhao, Cuiping Han, Zhigang Wei, Xin Ye

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The first multiple center prospective study of rhFSH CTP in patients undergoing assisted reproductive technology in China by Longmei Wu, Huayan Yin, Lingfang Guan, Guanjian Li, Junqiang Zhang, Qunshan Shen, Xiaoqing Ni, Chao Wang, Tianjuan Wang, Hao Geng, Chuan Xu, Yunxia Cao, Xiaojin He, Bing Song

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Enabling ultra-flexible inorganic thin-film-based thermoelectric devices by introducing nanoscale titanium layers by Ming Tan, Xiao-Lei Shi, Wei-Di Liu, Yong Jiang, Si-Qi Liu, Tianyi Cao, Wenyi Chen, Meng Li, Tong Lin, Yuan Deng, Shaomin Liu, Zhi-Gang Chen

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Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway by Yiwen Cao, Huan Zhao, Shuyin Lin, Junqi Chen, Jingli Xiong, Zhijun Zeng, Ziyu Long, Yingru Su, Yingqi Zhong, Lingru Zhao, Mingshan Zhang, Junbiao Wu, Yuan Zhou, Jiuyao Zhou

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Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9 by Cancan Zhou, Zhengyuan Feng, Weikun Qian, Zeen Zhu, Ruiqi Cao, Qiqi Wang, Wunai Zhang, Rujuan Liu, Shuai Wu, Jie Hao, Zheng Wang, Qingyong Ma, Zheng Wu, Xuqi Li

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Evaluation of suitability of CO2 geologic storage in deep saline aquifers in Lindian area of Songliao Basin by Yongfa MA, Junling DONG, Xu WANG, Lan HE, Xuejun ZHOU, Ling LIU, Guang LIU, Zhenzhen SHI, Guannan CAO, Yan LIU, Xiuhai LI, Tian LIU, Tao ZHAN, Chang LI

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Severity Assessment of COVID-19 Using a CT-Based Radiomics Model by Zhigao Xu, Lili Zhao, Guoqiang Yang, Ying Ren, Jinlong Wu, Yuwei Xia, Xuhong Yang, Milan Cao, Guojiang Zhang, Taisong Peng, Jiafeng Zhao, Hui Yang, Jinfeng Hu, Jiangfeng Du

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Koro Syndrome: Epidemiology, Psychiatric and Physical Risk Factors, Clinical Presentation, Diagnosis, and Treatment Options by Yukino N. Strong, David Y. Cao, Jessica Zhou, Maya A. Guenther, Danyon J. Anderson, Alan D. Kaye, Brian E. Blick, Prathima R. Anandi, Hirni Y. Patel, Ivan Urits

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USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis by Jiawei Cao, Tao Wu, Tong Zhou, Zewei Jiang, Yinrui Ren, Jiawei Yu, Jiayi Wang, Changrui Qian, Guang Wu, Licai He, Hongzhi Li, Rixu Lin, Min Liu, Haihua Gu

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Evaluation of the transmission-blocking potential of Plasmodium vivax antigen Pvg37 using transgenic rodent parasites and clinical isolates by Di Zhang, Yan Zhao, Dongyan Liu, Fei Liu, Pengbo Liu, Biying Zhang, Zifang Wu, Wanlapa Roobsoong, Sirasate Bantuchai, Sataporn Thongpoon, Piyarat Sripoorote, Meilian Wang, Liwang Cui, Yaming Cao

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Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System by Shuaishuai Zhang, Junqin Li, Huijie Jiang, Yi Gao, Pengzhen Cheng, Tianqing Cao, Donglin Li, Jimeng Wang, Yue Song, Bin Liu, Hao Wu, Chunmei Wang, Liu Yang, Guoxian Pei

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Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing by Mangle Chen, Donghai Wang, Jiali Yang, Yuhao Cao, Xuemei Song, Yuwen Lu, Hongying Zheng, Jiejun Peng, Guanwei Wu, Jian Wu, Junmin Li, Jianping Chen, Fei Yan, Shaofei Rao

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High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis by Peng Zou, Tianjing Li, Zixuan Cao, Erwan Yang, Mingdong Bao, Haofuzi Zhang, Zhuoyuan Zhang, Dan Liu, Min Zhang, Xiangyu Gao, Junmiao Ge, Xiaofan Jiang, Zhicheng Tian, Peng Luo

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Methodology for evidence-based urology——evidence classification and retrieval by WANG Yunyun, QIN Changjiang, TONG Tiejun, MA Bin, CAO Shiyi, ZHANG Chao, REN Xuequn, LI Xiaodong, ZHANG Miao, WENG Hong, WANG Yang, JIN Yinghui, YANG Lu, ZENG Xiantao

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Genome-wide association study identifies candidate genes affecting body conformation traits of Zhongwei goat by Mingxuan Han, Xinbo Wang, Haidong Du, Yanlong Cao, Zhanqiang Zhao, Shuran Niu, Xuxu Bao, Youjun Rong, Xiaofang Ao, Furong Guo, Qincheng Xia, Fangzheng Shang, Ruijun Wang, Yanjun Zhang

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Establishing a preoperative predictive model for gallbladder adenoma and cholesterol polyps based on machine learning: a multicentre retrospective study by Yubing Wang, Chao Qu, Jiange Zeng, Yumin Jiang, Ruitao Sun, Changlei Li, Jian Li, Chengzhi Xing, Bin Tan, Kui Liu, Qing Liu, Dianpeng Zhao, Jingyu Cao, Weiyu Hu

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Substituting time spent in physical activity and sedentary time and its association with cardiovascular disease among northwest Chinese adults by Yutong Wang, Peiying Yang, Huimeng Liu, Suixia Cao, Jingchun Liu, Yating Huo, Kun Xu, Binyan Zhang, Mengchun Wang, Qian Huang, Chunlai Yang, Lingxia Zeng, Shaonong Dang, Baibing Mi

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Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef by Marko Terzin, Steven J. Robbins, Sara C. Bell, Kim-Anh Lê Cao, Renee K. Gruber, Pedro R. Frade, Nicole S. Webster, Yun Kit Yeoh, David G. Bourne, Patrick W. Laffy

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