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Identification and mechanistic insights of cell senescence-related genes in psoriasis
Published 2025-01-01“…The intersection of DEGs with cell senescence-related genes from the CellAge database was used to identify the candidate genes. Protein-protein interaction networks, Gene Ontology, and Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted to explore the functions and pathways of these genes. …”
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Shared rare genetic variants in multiplex autism families suggest a social memory gene under selection
Published 2025-01-01“…This study aimed to identify genes affected by rare variants shared by siblings with ASD and validate the function of a candidate gene FRRS1L. By integrating the whole genome sequencing data of 866 multiplex families from the Hartwell Foundation’s Autism Research and Technology Initiative and Autism Speaks MSSNG project, we identified rare variants shared by two or more siblings with ASD. …”
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Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study
Published 2025-02-01“…Our research sheds light on the viability of these E. angustifolia compounds as ZIKV RDRP inhibitors, laying a foundation for further experimental research in developing novel antiviral treatments against ZIKV infections.…”
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Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from <i>Lycosa erythrognatha</i> Spider Venom
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A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus
Published 2024-11-01“…Overall the results provide a key foundation for examining the mechanisms of molecular diversity and patterning in the name sake of the phylum Echinodermata.…”
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Crystal structure modulating performances for 213-nm GeO2 solar-blind photodetectors via DC reactive magnetron sputtering method
Published 2025-02-01“…Our findings suggest that the GeO2 thin film is a candidate material for optoelectronic device applications and will provide a facile and innovative strategy to develop the solar-blind photodetector.…”
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Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations
Published 2020-01-01“…By integrating multiple layers of analysis, we suggested that PPARD might be a main candidate in the pathogenesis of SLE.…”
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Construction of Shoot Apical Meristem cDNA Yeast Library of <i>Brassica napus</i> L. and Screening of Proteins That Interact with the Inflorescence Regulatory Factors BnTFL1s
Published 2024-12-01“…<i>BnTFL1s</i> (<i>BnaA10.TFL1</i> and <i>BnaC09.TFL1</i>), which encode the transcription factor <i>TERMINAL FLOWER 1 (TFL1),</i> have previously been identified as candidate genes controlling this trait through map-based cloning. …”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus)
Published 2025-01-01“…Our results suggest that ClPAD4 might be the candidate gene responsible for lesion mimic in the clalm mutant. …”
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Testbed Configuration for Minimizing PAPR in GFDM Systems Through a Novel Companding Approach
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The endocannabinoid system’s genetic polymorphisms in sickle cell anemia patients
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The emerging role of blood-based biomarkers in early detection of colorectal cancer: A systematic review
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A Review of the Therapeutic Potential of Ginseng and Its Bioactive Components in Nonalcoholic Fatty Liver Disease
Published 2025-01-01“…This analysis aims to provide a theoretical foundation for the development of ginseng -based drugs for combating NAFLD.Keywords: ginseng, bioactive components, NAFLD, NASH…”
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Development of a problem-oriented index system for evaluating the integration of medical treatment and prevention at county level: a Delphi study based on the rainbow model
Published 2024-12-01“…MethodsUsing the rainbow model as a theoretical foundation, a theoretical framework and a pool of candidate indicators for evaluating county-level medical-preventive integration were established through policy analysis and literature review. …”
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Wheat Leaf Rust Effector Pt48115 Localized in the Chloroplasts and Suppressed Wheat Immunity
Published 2025-01-01“…Herein, we report a wheat leaf rust candidate effector protein Pt48115 that is highly expressed in the late stages of infection during wheat–<i>Pt</i> interaction. …”
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