Identification of Potential Selective PAK4 Inhibitors Through Shape and Protein Conformation Ensemble Screening and Electrostatic-Surface-Matching Optimization by Xiaoxuan Zhang, Meile Zhang, Yihao Li, Ping Deng

“…Our findings provide a novel approach for developing selective PAK4 inhibitors and lay the theoretical foundation for future anticancer drug design.…”
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OUTSTANDING RUSSIAN SCIENTISTS: DIMITRY AND ELENA WENTZEL by V. I. LEVIN

“…Wentzel in the field of ballistics, his contribution to publishing textbooks for military universities, his experience in training highly qualified personnel (candidates, doctors, academicians), his scientific and organizational activities (the creation of the Faculty of Armaments in the VVIA, the foundation of the Academy of Artillery Sciences of the USSR and others). …”
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Analysis of unmapped regions associated with long deletions in Korean whole genome sequences based on short read data by Yuna Lee, Kiejung Park, Insong Koh

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A Systematic Review of Theories on Family Business Internationalization by Jahangir Yadollahi Farsi, Majid Pourmesgari

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Blood-based prognostic scores and early dynamics under immunotherapy to select patients with metastatic solid tumors for continuing immune check-point inhibition: a prospective lon... by Javier García-Corbacho, Alberto Indacochea, Iván Victoria, Débora Moreno, Laura Angelats, Azucena E. González Navarro, Laura Mezquita, Fara Brasó-Maristany, Patricia Galván, Begoña Mellado, Nuria Viñolas, Tamara Sauri, Miquel Nogué, Barbara Adamo, Joan Maurel, Estela Pineda, Lydia Gaba, Oscar Reig, Neus Basté, Esther Sanfeliu, Manel Juan, Aleix Prat, Francesco Schettini

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Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration by Xiao Yu, Xiaopeng Zhang, Hazrat Bilal, Chang Shi, Lei Sun

“…Collectively, our findings highlight the critical role of CRGs in AMI, providing a foundation for improved diagnostic approaches and novel therapeutic targets.…”
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Discovering natural products as potential inhibitors of SARS-CoV-2 spike proteins by Muhammad Alqaaf, Ahmad Kamal Nasution, Mohammad Bozlul Karim, Mahfujul Islam Rumman, Muhammad Hendrick Sedayu, Retno Supriyanti, Naoaki Ono, Md. Altaf-Ul-Amin, Shigehiko Kanaya

“…Fourteen SMs were predicted through computational analysis as potential candidates for inhibiting the three major types of S proteins. …”
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Absorptive capacity in startups: A systematic literature review by Ximena Alejandra Flechas Chaparro, Ricardo Kozesinski, Alceu Salles Camargo Júnior

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Predictive Analytics of In-Service Bridge Structural Performance from SHM Data Mining Perspective: A Case Study by Qiwen Jin, Zheng Liu, Junchi Bin, Weixin Ren

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Pénétrer le monde des morts by Katerina Kerestetzi

“…This ‘love’ for the dead is a keystone of Palo Monte and the foundation on which paleros ritual identity is built.…”
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Artificial Intelligence in Nursing Education: A Cross-sectional UTAUT Analysis Study by Latifah H Alenazi

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Innovative ecosystems behind regional smart specializations: The role of social, cognitive and geographical proximity by Elżbieta Wojnicka-Sycz, Marcin Kaczyński, Piotr Sycz

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Improvement of Hanwoo (Korean beef cattle) by selecting a giant cow and applying ovum pick-up and in vitro production technologies by Yeon-Gil Jung, Seungki Jung, Hyonsok Sol, Yeonsub Jung, Na Ahn, Sangho Roh

“…The semen of three candidate sires from the age of 22 months were collected and frozen, and the calves were produced by artificial insemination. …”
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An in-depth study of indolone derivatives as potential lung cancer treatment by Mohammed Er-rajy, Mohamed El fadili, Radwan Alnajjar, Sara Zarougui, Somdutt Mujwar, Khalil Azzaoui, Hatem A. Abuelizz, Belkheir Hammouti, Menana Elhallaoui

“…These comprehensive results highlight the potential of the selected indolone derivatives as viable drug candidates and provide a solid foundation for future optimization efforts aimed at developing novel PDK1 inhibitors for cancer therapy.…”
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Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis by Yan Lin, Yu Dong, Yanfeng Gao, Ranran Shi, Yubing Li, Xiuman Zhou, Wenwen Liu, Guodong Li, Yuanming Qi, Yahong Wu

“…First, three online software were used to predict HLA-A2-restricted epitopes. Then, the candidate epitopes were confirmed with the T2A2 cell binding affinity and peptide/MHC (pMHC) complex stability assays and in vitro immune activity experiments. …”
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Editorial by Ann-Kristin Kölln, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

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Computational and GC-MS screening of bioactive compounds from Thymus Vulgaris targeting mycolactone protein associated with Buruli ulcer by Muhammad Naveed, Imran Ali, Tariq Aziz, Ayesha Saleem, Zeerwah Rajpoot, Sameera Khaleel, Ayaz Ali Khan, Mitub Al-harbi, Thamer H. Albekairi

“…This work aims to address these challenges by employing computational methods to identify therapeutic candidates from organic compounds, which may be developed into more effective therapies for Buruli ulcer. …”
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Multi-objective optimization of graphene far-infrared paddy drying process based on response surface methodology by Jiyou An, Yuanjie Du, Jianchun Yan, Hai Wei, Huanxiong Xie

“…Graphene exhibits exceptional electrothermal conversion efficiency, making it a promising candidate as a novel heat source for far-infrared drying. …”
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Fine mapping and expression characteristics analysis of male-sterile gene BrRNR1 in Chinese cabbage (Brassica rapa L. ssp. pekinensis) by Meihui Xue, Jiahang Li, Ruiqi Liao, Junjie Xu, Mingwei Zhou, Runpeng Yao, Zhiyong Liu, Hui Feng, Shengnan Huang

“…Conclusion Our study is the first to characterize the function of BrRNR1 gene associated with male sterility and lays a foundation for exploring the molecular mechanism of anther abortion caused by the mutation in BrRNR1 gene of Chinese cabbage.…”
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Eco-biofabrication of silver nanoparticles from Azadirachta indica, Gymnema sylvestre, and Moringa oleifera for lung cancer treatment by Tanya Muthu, Ravi Adusumalli, Sathish Kumar Vemuri, M. Indira Devi, P. Pavan Kumar, Rajkiran Reddy Banala, A. V. Gurava Reddy

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