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    Effect of Electroacupuncture on Hippocampal Functional Activity and Molecular Expression Profile in Rats with Vascular Cognitive Impairment by WANG Zeyu, DING Yanyi, DAI Yaling, YANG Minguang, HUANG Jia, ZHANG Shenghang

    Published 2021-12-01
    “…A total of 399 genes with 2-fold differential expression of hippocampal mRNA between the electroacupuncture group and the model group (<italic>P</italic>&lt;0.05), of which 166 genes (such as Klhl14, Bmp3, Npsr1, Cacna1e, etc.) were up-regulated, of which 233 genes (such as Insl6, Ube2k, Cdkn1c, Camp, Upk1b,etc.) were down-regulated.ConclusionThe "Tongdu Tiaoshen" electroacupuncture at Baihui and Shenting acupoints can improve the cognitive function of rats with vascular cognitive impairment, and its mechanism may be related to enhance the function of hippocampus, prefrontal lobes and other brain regions, regulate the expression of calcium ions and energy metabolism-related molecules by regulating nerve activity activity.…”
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    Bioinformatics analysis of miR-2861 and miR-5011-5p that function as potential tumor suppressors in colorectal carcinogenesis by Alper Aytekin, Hikmet Kadakal, Deniz Mihcioglu, Turkan Gurer

    Published 2025-01-01
    “…Conclusion These findings imply that miR-2861 and miR-5011-5p might function as tumor suppressors in the development of CRC.…”
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    Role of BDNF-TrkB signaling in the improvement of motor function and neuroplasticity after ischemic stroke in rats by transcranial direct current stimulation by Yu Chen, Lin Mao, Qinxiang Zhou, Dingqun Bai, Yuhan Kong

    Published 2025-01-01
    “…Moreover, tDCS can control neuronal excitability, promote axonal regeneration, and accelerate motor function recovery in ischemia reperfusion-injured rats.…”
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    Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II (CaMKII) Regulates Basal Cardiac Pacemaker Function: Pros and Cons by Tatiana M. Vinogradova, Edward G. Lakatta

    Published 2024-12-01
    “…Though the essential role of a high basal cAMP level and PKA-dependent phosphorylation for basal spontaneous SANC firing is well recognized, the role of basal CaMKII-dependent phosphorylation remains uncertain. …”
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    Adenosine cyclic phosphate with ultrasonic-assisted pectinase extraction alleviated allergic reactions in RBL-2H3 through inhibiting the influx of intracellular Ca2+ by Qiao Bai, Xiaoping Feng, Yu Wang, Chunyu Wu, Ye Liu, Jiao Sun, Tianli Yue, Fangyu Long

    Published 2023-05-01
    “…Moreover, the effect of cAMP on the anti-allergic function of action induced by immunoglobulin E (IgE) and its meschanism was investigated through establishing the sensitized cell model in rat basophilic leukemia (RBL-2H3) cells using dinitrophenylated (DNP)-bovine serum albumin (BSA)-IgE. …”
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    Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R) by Roberto Salvi, Amar Abderrahmani

    Published 2014-01-01
    “…Among the mechanisms that reduce β-cell activity is the inducible cAMP early repressor (ICER). ICER is an immediate early gene, which is rapidly induced by the cyclic AMP (cAMP) signaling cascade. …”
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    Inhibition of CFTR-mediated intestinal chloride secretion by nornidulin: Cellular mechanisms and anti-secretory efficacy in human intestinal epithelial cells and human colonoids. by Chamnan Yibcharoenporn, Thidarat Kongkaew, Nichakorn Worakajit, Rungtiwa Khumjiang, Praphatsorn Saetang, Saravut Satitsri, Vatcharin Rukachaisirikul, Chatchai Muanprasat

    Published 2024-01-01
    “…Nornidulin, a fungus-derived natural product from Aspergillus unguis, has previously been shown to inhibit cAMP-induced Cl- secretion in T84 cells (human intestinal cell lines). …”
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