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Contribution of a virtual magic camp to enhancing self-esteem in children with ADHD: A pilot study
Published 2021-07-01“… # Discussion This study supported the hypothesis that children with ADHD who participated in a four-week virtual magic camp experienced enhanced self-esteem. Future studies should investigate the holistic impact of magic camps on children and adolescents with ADHD and include measures that tap into other psychosocial attributes such as social functioning, social skills, and self-efficacy.…”
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Exploring the Analgesic Effect of Acupuncture on Knee Osteoarthritis Based on MLT/cAMP/PKA/CREB Signaling Pathway
Published 2025-01-01“…In addition, acupuncture significantly reduced the expression of the inflammatory factor MMP-3 in knee joint fluid and significantly increased the levels of MLT, AANAT, MT1, MT2, cAMP, PKA and CREB.Conclusion: By regulating sympathetic excitability, acupuncture may activate the MLT/cAMP/PKA/CREB signaling pathway, decrease inflammatory factor expression and slow down degradation of articular cartilage, resulting in the relief of knee pain.Keywords: acupuncture, knee osteoarthritis, MLT/cAMP/PKA/CREB pathway, melatonin…”
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The regulatory effects of (p)ppGpp and indole on cAMP synthesis in <i>Escherichia coli</i> cells
Published 2024-03-01“…Bacterial stress adaptive response is formed due to changes in the cell gene expression profile in response to alterations in environmental conditions through the functioning of regulatory networks. The mutual influence of network signaling molecules represented by cells’ natural metabolites, including indole and second messengers (p)ppGpp and cAMP, is hitherto not well understood, being the aim of this study. …”
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Age-related calcium signaling disturbance restricted cAMP metabolism and induced ovarian oxidation stress in laying ducks
Published 2025-01-01“…Moreover, the cyclic adenosine monophosphate (cAMP) concentration and cAMP synthase family related genes were also decreased in GCs of aged ducks. …”
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A Cost-Effective Epidemiological Exposition of Diphtheria Outbreak by the Optimal Control Model: A Case Study of Rohingya Refugee Camp in Bangladesh
Published 2024-01-01“…Here, the qualitative study of the model has been interpreted. An objective function has been regarded as a cost function introduced by the optimal controls and the diseases themselves. …”
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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus
Published 2017-01-01“…The role of EETs in synaptic function in the central nervous system is still largely unknown. …”
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Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
Published 2024-11-01“…Treatment with MMPP markedly attenuated oxidative stress levels, inhibited cyst growth, thereby improving renal function. Interestingly, we found that MMPP effectively inhibits a cyst-promoting gene program downstream of the cAMP-CREB pathway, a crucial signaling pathway implicated in ADPKD progression. …”
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Haploinsufficiency of PDE2A causes in mice increased exploratory behavior associated with upregulation of neural nitric oxide synthase in the striatum
Published 2025-02-01“…Phosphodiesterase 2 A (PDE2A) function is stimulated by cGMP to catabolize cAMP. …”
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Aberrant c-AMP signalling in richter syndrome revealed by single-cell transcriptome and 3D chromatin analysis
Published 2025-01-01“…Differentially expressed genes at TAD borders between CLL and DLBCL cells highlighted an enrichment of cAMP-mediated signalling. To substantiate the functional relevance of ATF1 and CAP1, the genes involve in cAMP-mediated signalling, in the context of cell proliferation, we have performed gain- and loss-of-function experiments in relevant cell lines. …”
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METAPHORICAL CONCEPTS AND THEIR IDEOLOGICAL FUNCTIONS IN ALURING VOTES FOR INDONESIAN PRESIDENCY
Published 2023-12-01“…Some conceptual metaphors drawn from their metaphorical expressions are NATION IS A BUILDING, functions to criticize that the building couldn’t stand on the lie, hiding the history of competitor candidate, Prabowo. …”
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Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation
Published 2025-02-01“…Methods: A long-acting GIPR agonist, GIP108, was used to probe the effect of sustained agonist exposure on cAMP responses in dispersed pancreatic islets using live cell imaging, with rechallenge cAMP responses after prior agonist treatment used to quantify functional desensitisation. …”
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Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential
Published 2025-06-01“…We delve into the link between miRNAs and T2D obesity and explore specific miRNA examples influencing GLP-1R function. Finally, the review explores the rationale for seeking alternatives to GLP-1RAs and highlights natural products with promising GLP-1 modulatory effects.…”
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PABPN1 functions as a downstream gene of CREB to inhibit the proliferation of preadipocytes
Published 2025-01-01“…Furthermore, we showed that PABPN1 functions as a downstream gene of CREB to regulate the proliferation of preadipocytes. …”
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How to Define Successful Stocking of Florida’s Freshwater Recreational Fisheries
Published 2019-09-01“…Well-planned stocking can not only improve recreational fishing but achieve broader research and management goals and help us to understand how fisheries function, both biologically and socioeconomically. …”
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How to Define Successful Stocking of Florida’s Freshwater Recreational Fisheries
Published 2019-09-01“…Well-planned stocking can not only improve recreational fishing but achieve broader research and management goals and help us to understand how fisheries function, both biologically and socioeconomically. …”
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