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23461
Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder
Published 2025-02-01“…The convolutional neural network (CNN) model, using variants with genome-wide P values less than E-02 (5516 SNPs), demonstrated the best performance with mean squared error (MSE) equals 0.012 (Accuracy = 0.83; Sensitivity = 0.90; Specificity = 0.75) in the validation dataset, 0.081 in an independent test dataset (Acc = 0.61, Sensitivity = 0.81; Specificity = 0.26). …”
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23462
MVP Risk score y nuevo diagnóstico de fibrilación auricular: estudio de cohorte prospectivo PREFATE
Published 2025-01-01“…Diseño: Estudio de cohorte prospectivo (1/01/2023-31/12/2024). Emplazamiento: Centros de atención primaria. …”
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23463
Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study
Published 2024-08-01“…The delta_FT4 (difference in FT4 from baseline) negatively correlated with TG increase at 1 week (p = 0.012) but not with low density lipoprotein cholesterol (LDL-C) increase at any week. …”
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23464
Effectiveness of a personalised self-management intervention for people living with long covid (Listen trial): pragmatic, multicentre, parallel group, randomised controlled trial
Published 2025-01-01“…No differences were found in social engagement (−2.07 (95% CI −5.36 to 1.22), P=0.218) or SF-12 physical health (0.32 (95% CI −0.93 to 1.57), P=0.612). …”
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23465
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23466
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23467
Recruiting Young People for Digital Mental Health Research: Lessons From an AI-Driven Adaptive Trial
Published 2025-01-01Get full text
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23468
神经胶质细胞系衍生神经营养因子和雄激素受体在手术诱导隐睾小鼠睾丸管周细胞中的表达
Published 2024-01-01“…结果对照组4 d、7 d、14 d小鼠的睾丸体积分别为(125.58±19.22)mm<sup>3</sup>、(123.45±20.12)mm<sup>3</sup>、(140.09±13.62)mm<sup>3</sup>;睾丸各级生精细胞排列整齐、层次清楚,可见较多精子细胞,生精小管周围管周细胞形态规则,呈梭形围绕小管周围,细胞厚度均一;ARmRNA的表达量分别为1.00±0.05、1.06±0.07、1.19±0.13GDNFmRNA的表达量分别为1.00±0.04、1.09±0.05、1.10±0.07;AR蛋白的表达量分别为1.01±0.01、0.79±0.02、1.01±0.04;GDNF蛋白的浓度分别为(18.68±0.43)pg/mL、(14.39±0.36)pg/mL、(16.88±0.37)pg/mL。…”
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23469
Desigualdades relacionadas à participação em aulas de Educação Física entre adolescentes sul-americanos: uma análise com 173.288 participantes
Published 2024-11-01“…Adolescentes mais velhos (≥16 anos) apresentaram maior prevalência de 0 [1,50 (1,11; 2,02)] e 1 dia/semana [1,18 (1,05; 1,33)], e menor prevalência de 2 [0,70 (0,58; 0,85)] e ≥3 dias/semana de aulas de EF [0,73 (0,60; 0,89)] em comparação aos adolescentes mais jovens (12-13 anos). Adolescentes que relataram insegurança alimentar apresentaram maior prevalência de 0 [1,20 (1,06; 1,36)] e ≥3 dias/semana de aulas de EF [1,07 (1,02; 1,12)]. …”
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23470
Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks
Published 2025-01-01“…Similarly, Bacteroidetes showed significant differences between the jejunum (2.21%) and the rumen (36.54%), abomasum (23.81%), and colon (28.12%). At the genus level, Rikenellaceae_RC9_gut_group and Christensenellaceae_R-7_group were dominant in both the rumen and abomasum. …”
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23471
Research on entity recognition and alignment of APT attack based on Bert and BiLSTM-CRF
Published 2022-06-01“…Methods: An automatic extraction method of APT attack knowledge that integrates entity recognition and entity alignment is designed. Firstly, 12 entity categories are designed according to the characteristics of APT attacks. …”
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23472
The impact of preoperative venous thromboembolism on patients undergoing TURBT: Perioperative outcomes and healthcare costs from US insurance claims data
Published 2025-01-01“…Additionally, preoperative VTE increased the risk of novel VTE events following TURBT (aOR 17.30, 95% CI 16.05–18.65), hospital length of stay (aOR 2.23, 95% CI 1.90–2.62), readmissions (aOR 1.47, 95% CI 1.39–1.56), and hospital associated costs (aOR 1.17, 95% CI 1.12–1.23). DVT and non‐minor TURBT procedures did not increase the risk of any, infectious, or haemorrhagic complications, but other associations were maintained regardless of the severity of VTE (PE, DVT, SVT) or TURBT extent (minor/major). …”
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23473
واکاوی تغییرات زمانی- مکانی شاخصهای حدی بارش تحت تأثیر تغییر اقلیم در ایران
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23474
Acute exacerbations in patients with progressive pulmonary fibrosis
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23476
Stenotrophomonas maltophilia bacteremia in adult patients with hematological diseases: clinical characteristics and risk factors for 28-day mortality
Published 2025-01-01“…This study retrospectively analyzed the clinical characteristics and risk factors for 28-day mortality among 140 adult hematological patients diagnosed with SM bacteremia from January 2012 to July 2023. he overall 28-day mortality was 31.43% (44/140), with a median age of 44 years. …”
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23477
Reproductive hormone profiles and gametogenesis in female of giant gouramy (Osphronemus gouramy)
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23479
Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context
Published 2025-01-01“…The incidence rate rose from 0.25 (95% UI, 0.18–0.33) per 100,000 individuals in 1990 to 0.28 (95% UI, 0.19–0.38) per 100,000 individuals in 2021, an overall increase of 12.60% (95% UI, −14.62% to 49.12%). Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the low-to-mid SDI regions for incidence (1.87%; 95% CI, 1.64%–2.10%), mortality (1.22%; 95% CI, 1.09%–1.34%), and DALYs (1.36%; 95% CI, 1.15%–1.57%). …”
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23480