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Expediente
Published 2024-11-01“…/dez. 2024 ISSN 2358-1824 Cadernos Ibero-Americanos de Direito Sanitário (CIADS) é um periódico trimestral, de acesso aberto, editado pelo Programa de Direito Sanitário da Fundação Oswaldo Cruz/Brasília desde 2012. É dirigido a professores, pesquisadores e estudantes de Direito, Ciências da Saúde e Ciências Sociais; operadores do Direito; profissionais de saúde e gestores de serviços e sistemas de saúde. …”
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23063
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23064
异氟醚和七氟醚对新生大鼠皮质凋亡以及Akt和Bcl-xl/Bad表达的不同影响
Published 2011-01-01“…【目的】研究相同麻醉深度的异氟醚和七氟醚对新生大鼠皮质神经细胞凋亡以及Akt和Bcl-xl/Bad蛋白表达的影响【方法】 5窝出生后7 d(P7)的新生大鼠,每窝取11只(总共55只),每窝随机分为异氟醚组(I组)4只,七氟醚组(S组)4只和对照组(C组)3只各组分别吸入1.1%异氟醚或1.8%七氟醚或空气4h,在麻醉结束时每窝每组各取一只幼鼠经心脏穿刺抽血检测血气和血糖的变化(n = 5);在麻醉结束后2 h每窝每组各取1只幼鼠灌注取脑,免疫组织化学法检测顶叶皮质区(PC)Caspase-3表达(n = 5);另外,C组在麻醉处理0 h,I组和S组分别在麻醉2 h,4 h每窝各取一只幼鼠取新鲜脑皮质,Western blot检测磷酸化Akt,以及Akt,Bcl-xl和Bad表达的变化(n = 5)组间资料的比较采用单因素方差分析【结果】 I组Caspase-3阳性细胞数为(27.12 ± 5.22)个/mm2,较对照组[(3.15 ± 0.59)个/mm2]增加751.11%(P < 0.001),比S组[(9.05 ± 1.76)个/mm2]增加199.67%(P < 0.01);S组Caspase-3表达与对照组比较差异无统计学意义I组磷酸化Akt表达在麻醉2 h较对照组降低66.31%(P<0.01),4 h呈回升趋势;S组在2 h和 4 h与对照组无统计学差异I组Bad表达在麻醉2 h较对照组增加162.2%(P<0.05),S组Bad表达在2 h和4 h与对照组差异均无统计学意义I组和S组在2 h和4 hBcl-xl表达与对照组差异均无统计学意义I组Bcl-xl/Bad比值在麻醉2 h较对照组降低42.85%(P<0.01),S组在2 h和4 h与对照组无统计学差异【结论】 0.5MAC异氟醚比七氟醚诱导更多新生大鼠大脑皮质神经细胞凋亡,异氟醚抑制Akt磷酸化并降低Bad表达,下调Bcl-xl/Bad比值可能是其诱导神经细胞凋亡的机制之一;七氟醚不会影响Akt磷酸化和Bcl-xl/Bad比值…”
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23065
Daratumumab followed by tocilizumab for treatment of late antibody-mediated rejection in renal transplant recipients with high or moderate levels of de novo donor-specific antibodi...
Published 2025-01-01“…In addition, capillary C4d deposition became negative in all patients (P = 0.001), and the mean score of i-IFTA was significantly reduced (P = 0.012). Other chronic injury scores did not change significantly. …”
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23067
The use of ambon banana (Musa paradisiaca var. sapientum) stems flour in grouper (Epinephelus lanceolatus ♂× Epinephelus fuscoguttatus ♀) floating net cage nursery
Published 2022-02-01“…The groupers (8.27 ± 0.20 cm length and 11.69 ± 0.50 g weight) were reared in 1 m × 1 m × 1.5 m floating net cages with a stocking density of 112 fish /m3 for 42 days. The feed was commercial feed with 46% and 48% protein, which was added with 30 g/kg of ambon banana stems flour with a coating method. …”
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Ethnic and racial discrimination in maternal health care in Mexico: a neglected challenge in the search for universal health coverage
Published 2025-01-01“…Our study included n = 72,873 (N = 23,245,468) Mexican women aged 12–54 with recent live births. We defined ECMH as adequate antenatal care (ANC), skilled and/or institutional delivery care, timely postpartum care, and complication-free postpartum/puerperium. …”
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Ten pressure points in primary care during COVID-19: findings from an international narrative review
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23071
Comparative analysis of ambient, in-home, and personal exposures reveals associations between breathing zone pollutant levels and asthma exacerbations in high-risk children
Published 2025-01-01“…Children requiring corticosteroid treatment for asthma exacerbation within 60 days of exposure monitoring had 1.98, 2.21 and 2.04 times higher personal exposures to BrC (p < 0.001; 95% CI: 1.43–2.37), ETS (p = 0.007; 95% CI: 1.25–3.91), and endotoxin (p = 0.012; 95% CI: 1.14–3.68), respectively. Conclusions Although in-home monitoring was correlated with personal exposure to PM10 and NO2, in-home detection of ETS and BrC was not associated with personal exposures. …”
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23072
The growth of eel fed with different protein level and protein-energy ratio
Published 2015-10-01“…Kinerja pertumbuhan optimal dicapai oleh kadar protein dan rasio energi protein pakan 45,38%; 12,27 kkal GE/g dan 49,60%; 11,31 kkal GE/g. …”
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23073
前列地尔治疗高龄糖尿病并慢性肾脏病患者疗效和安全性
Published 2015-01-01“…【目的】 探讨前列地尔治疗80岁以上糖尿病合并慢性肾脏病患者的疗效及安全性。【方法】 2012年10月至2013年5月我院住院的80岁以上糖尿病合并慢性肾脏病患者共52例,按性别分层随机分为A组及B组。…”
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Studying the Digital Intervention Engagement–Mediated Relationship Between Intrapersonal Measures and Pre-Exposure Prophylaxis Adherence in Sexual and Gender Minority Youth: Second...
Published 2025-01-01“…Participants with depressive symptoms and anxiety symptoms had 3.4 (OR 3.42, 95% CI 0.95-12) and 3.5 (OR 3.51, 95% CI 1.06-11.55) times higher odds of PrEP nonadherence, respectively. …”
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The Effect of Wheat Residues and Vermicompost on the Quality Characteristics of Corn (Zea mays L.) Forage and Soil Fertility
Published 2025-09-01“…The highest amount of organic carbon (0.212 %) and phosphorus (5.07 mg.lit-1) were achieved in the integrated system of 10% vermicompost + 90% wheat. …”
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23077
Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort
Published 2025-01-01“…Higher melamine concentration was associated with longer gestational age (β^ per IQR increase of log2-transformed: 0.082 [95 % CI: −0.012, 0.177]; 2nd vs 1st tertile: 0.173 [-0.048, 0.394]; 3rd vs 1st tertile: 0.186 [-0.035, 0.407]). …”
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Effectiveness of ICS/LABA and LAMA/LABA in COPD due to biomass
Published 2024-11-01“…Results There were no differences in exacerbation rates between patients receiving FF/VI or UMEC/VI in either the COPD-B (0.07 (95% CI 0.03–0.13), 0.06 (95% CI 0.03–0.12)) or COPD-C group (0.06 (95% CI 0.04–0.11), 0.08 (95% CI 0.05–0.13)), nor in the time of first exacerbation, nor FEV1 and IC. …”
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23080
Rapid literature mapping on the recent use of machine learning for wildlife imagery
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