Analysis of Circulating Plasma MicroRNA Profile in Low-Grade and High-Grade Glioma – A Cross-Sectional Study [version 1; peer review: 2 approved, 1 approved with reservations, 1 no... by Sekar Safitri, Rachmat Andi Hartanto, Rusdy Ghazali Malueka, Bo Sun, Ery Kus Dwianingsih, Kusumo Dananjoyo, Ahmad Asmedi, Endro Basuki, Christina Megawimanti Sianipar, Yeshua Putra Krisnugraha

“…Out of these significant miRNAs, miR-518b, miR-1271-3p, and miR-598-3p showed the highest potential for distinguishing HGG from LGG, with area under curve (AUC) values of 0.912, 0.889, and 0.991, respectively. Conclusion miR-518b, miR-1271-3p, and miR-598-3p demonstrate significant potentials in distinguishing LGG and HGG.…”
Get full text

Dietary selenium peptide supplementation for increasing the growth of African catfish Clarias gariepinus by Muhammad Agus Suprayudi, Muhammad Roikhan Amanullah, Dedi Jusadi, Hasan Nasrullah, Ahmad Yazid Latif

“… Selenium is an essential micromineral that the body needs in modest amounts (0.2–12 mg/kg), yet it has important effects on the antioxidant defense, immune system, and digestive performance of aquatic species. …”
Get full text

Association of aerobic capacity and muscular strength with health-related quality of life in adolescents: A school-based cross-sectional study by Bianca Lins dos Santos, João Paulo Rodrigues dos Santos, José Damião Saraiva Gomes-Júnior, Eriston de Souza Bezerra, Samuel Lira da Silva Barbosa, Bárbara Gicélia da Silva Araújo, Fabio Thiago Maciel da Silva, João Pedro Magalhães, Vera Lúcia Zymbal, Eduardo Caldas Costa, Rodrigo Alberto Vieira Browne

“…Similarly, those with muscle strength in the healthy zone scored higher than in the needs improvement category (β=6.6; p=0.012). In the psychological domain, adolescents with aerobic capacity in the healthy zone (β=8.1; p=0.002) and needs improvement (β=5.9; p=0.027) also had higher scores than those at risk, as did those with healthy muscle strength compared to needs improvement (β=4.5; p=0.043). …”
Get full text

Risk factors and renal outcomes of AKI in children with secondary steroid-resistant nephrotic syndrome by Nannan Yu, XiaoJun Ouyang, Jie Li, Jie Gao, Shuhan Zeng, Hongjie Zhuang, Mengjie Jiang, Yuxin Pei, Xiaoyun Jiang

“…AKI was defined and classified in accordance with the 2012 Kidney Disease Improving Global Outcomes (KDIGO) guidelines.Results AKI was found in 67 (39.0%) of 172 hospitalizations with secondary SRNS. …”
Get full text

Stress Reduction in Perioperative Care: Feasibility Randomized Controlled Trial by Haridimos Kondylakis, Irene Alice Chicchi Giglioli, Dimitrios Katehakis, Hatice Aldemir, Paul Zikas, George Papagiannakis, Santiago Hors-Fraile, Pedro L González-Sanz, Konstantinos Apostolakis, Constantine Stephanidis, Francisco J Núñez-Benjumea, Rosa M Baños-Rivera, Luis Fernandez-Luque, Angelina Kouroubali

“…Overall, patients in the intervention study spent 17.12% less days in the hospital. Besides these individual scores, the intervention group shows more positive relationships among the psychological dimensions of self-efficacy, self-management, and mental well-being, suggesting that the CARINAE solution could have a positive effect and impact on the reduction of stress and negative emotions. …”
Get full text

Application of Bacillus probiotic to prevent Aeromonas hydrophilla infection in Clarias sp. by Mohammad Faizal Ulkhaq, , Widanarni, Angela Mariana Kusumastuti

Get full text

The effectiveness of forest onion Eleutherine bulbosa simplisia to prevent Streptococcus agalactiae infection on Nile tilapia Oreochromis sp. by Amalia Istiqomah, Widanarni Widanarni, Munti Yuhana

“…Experimental treatments included maintaining tilapia with the addition of forest onion simplisia at 12.5, 25, and 50 g/kg feed, negative and positive controls. …”
Get full text

Neurological syndromes associated with COVID-19: a multicenter study in Brazil by Aline de Moura Brasil Matos, Andre Borges Ferreira Gomes, Fernanda Martins Maia Carvalho, Francisco Tomaz Meneses de Oliveira, Lohana Santana Almeida da Silva, Flavia Esper Dahy, Joao Victor Luisi de Moura, Marcela Vieira Freire, Jose Ernesto Vidal, Rosa Maria Nascimento Marcusso, Jerusa Smid, Victor Rebelo Procaci, Rodrigo Meireles Massaud, Felipe Von Glehn, Jorge Casseb, Camila Malta Romano, Augusto Cesar Penalva de Oliveira, on behalf of NeurocovBR study group

“…Those developing vascular syndromes patients were 3 times more likely to require ICU (χ2 (1) = 37.12, p < 0.01, OR = 3.78) and 4 times more likely to die (χ2 (1) = 58.808, p < 0.01, OR = 4.73) than patients with vascular syndromes due to different etiologies. …”
Get full text

Endoscopic Submucosal Dissection of the Angiolipoma at Hypopharynx-Esophageal Introitus by Lu Liu, Feng Miao, Hai-Mei Guo, Nuo Li, Shu-Hua Jiao, Shuang Cai, Peng-Liang Liu, Shan-Shan Zhang, Jia Ma, Yang Weng, Ying Sun, Yin-Si Tang, Feng Zhao, Yan Zheng, Shen Zhang, Yan Yang, Yang Yu, Lei Tian, Zhi-Feng Zhao

Get full text

Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders by Tábatha de Oliveira Silva, Guilherme Lunardon, Caroline A. Lino, Amanda de Almeida Silva, Shiju Zhang, Maria Cláudia Costa Irigoyen, Yao Wei Lu, John D. Mably, Maria Luiza M. Barreto-Chaves, Da-Zhi Wang, Gabriela P. Diniz

Get full text

Male sex ratio of red tilapia Oreochromis sp. after soaking in different concentrations of coconut milk at larvae stadia by Fajar Maulana, Agus Oman Sudrajat, Andre Permana, Lina Mulyani, Harton Arfah

“…Tilapia fish larvae were immersed in coconut milk for 12 hours and then reared for 60 days at 100 larvae for each rearing container. …”
Get full text

Genetic variability and performance of Asian swamp eel Monopterus albus (Zuiew, 1793) from West Java cultured in saline water medium by Dinar Tri Soelistyowati, Ahmad Fahrul Syarif, Ridwan Affandi, Dendi Hidayatullah

Get full text

Emergence and clinical challenges of ST11-K64 carbapenem-resistant Klebsiella pneumoniae: molecular insights and implications for antimicrobial resistance and virulence in Southwes... by Linlin LI, Jiahui Liang, Huan Zhang, Jing Guo, Shan LI, Meng Li

“…Hematological diseases were less associated with ST11-K64 CRKP infection compared to non-ST11-K64 strains (P = 0.012). However, central intravenous catheter use (P = 0.001), mechanical ventilation (P = 0.002), tracheal intubation (P = 0.006), and tracheotomy (P = 0.041) were significantly more common in ST11-K64 CRKP cases. …”
Get full text

Treatment outcomes and associated factors among patients with multidrug-resistant tuberculosis in Ashanti Region, Ghana: a retrospective, cross-sectional study by Peter Agyei-Baffour, Victoria Panford, Emmanuel Kumah, Collins Kokuro, Prince Owusu Adoma, Michael Afari Baidoo, Adam Fusheini, Samuel Egyakwa Ankomah, Samuel Kofi Agyei

“…Patients who were female (adjusted OR (AOR)=1.27, 95% CI: 1.18 to 1.39, p=0.023), younger (AOR=0.53, 95% CI: 0.19 to 2.11, p=0.012), had a higher level of education (AOR=1.12, 95% CI: 0.65 to 1.90, p=0.034), had a baseline body mass index of 18.5 kg/m2 or above (AOR=1.57, 95% CI: 1.23 to 2.47, p=0.011) and those who did not have a history of TB (AOR=0.47, 95% CI: 0.10 to 0.75, p=0.028) were more likely to have successful MDR-TB treatment outcomes.Conclusions Favourable treatment outcomes for patients with MDR-TB can be achieved in a resource-limited country. …”
Get full text

Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies by Cassandra Snipes, Cornelia Dorner‑Ciossek, Brendan D Hare, Olya Besedina, Tim Campellone, Mariya Petrova, Shaheen E Lakhan, Abhishek Pratap

“…MethodsTwo multicenter, exploratory, single-arm studies (study 1: CT-155-C-001 and study 2: CT-155-C-002) enrolled adults with schizophrenia and ENS receiving stable antipsychotic medication (≥12 weeks). Participants had access to CT-155 beta and were presented with daily in-app activities during a 3-week orientation phase that included lessons designed to facilitate building of a DWA. …”
Get full text

Proteomic profiling of bronchoalveolar lavage fluid uncovers protein clusters linked to survival in idiopathic forms of interstitial lung disease by Linh T. Ngo, Michaella J. Rekowski, Devin C. Koestler, Takafumi Yorozuya, Atsushi Saito, Imaan Azeem, Alexis Harrison, M. Kristen Demoruelle, Jonathan Boomer, Bryant R. England, Paul Wolters, Philip L. Molyneaux, Mario Castro, Joyce S. Lee, Joshua J. Solomon, Koji Koronuma, Michael P. Washburn, Scott M. Matson

Get full text

Global decadal measurements of methanol, ethene, ethyne, and HCN from the Cross-track Infrared Sounder by K. C. Wells, D. B. Millet, J. F. Brewer, V. H. Payne, K. E. Cady-Pereira, R. Pernak, S. Kulawik, S. Kulawik, C. Vigouroux, N. Jones, E. Mahieu, M. Makarova, T. Nagahama, I. Ortega, M. Palm, K. Strong, M. Schneider, D. Smale, R. Sussmann, M. Zhou

“…We update the Retrieval of Organics from CrIS Radiances (ROCR) algorithm developed previously for isoprene to explicitly account for the spectral signal dependence on the VOC vertical profile shape, and we apply this updated retrieval (ROCRv2) to derive column abundances for the targeted species across the full Suomi NPP CrIS record (2012–2023). The CrIS data are well correlated with ground-based Network for the Detection of Atmospheric Composition Change (NDACC) retrievals for methanol (<span class="inline-formula"><i>r</i></span> <span class="inline-formula">=</span> 0.77–0.84); HCN and ethyne exhibit lower correlations (<span class="inline-formula"><i>r</i></span> <span class="inline-formula">=</span> 0.36–0.44 and 0.56–0.65, respectively) with an apparent 40 % CrIS–NDACC disparity for ethyne. …”
Get full text

National guidelines for physical activity in early childhood in American countries: a scoping review by Paulo Henrique Guerra, Anastácio Neco Souza Filho, Carla Menêses Hardman, Clarice Lucena Martins, Daniel da Rocha Queiroz, Larissa Rosa Silva, Paula Fabricio Sandreschi, Rildo de Souza Wanderley Junior, Daniel Umpierre, Mauro Virgilio Gomes Barros

Get full text

Efficacy of Andrographis paniculata, Psidium guajava and Piper betle as Prevention on Motile Aeromonad Septicaemia Infection in African Catfish (Clarias sp.) by D. Wahjuningrum, . Tarono, S.L. Angka

Get full text

A Systematic Review on Poisoned Patients as Potential Organ Donors by Kattamreddy Ananth Rupesh, Anirudh Suseel Nalumaru, Mohit Kumar Moses Thathapudi, Omkarnath Sivarchaka, Deekshitha Alla

“…However, the literature presents a plethora of instances showcasing successful organ donations arising from a diverse array of poisonings, ranging from nicotine to hemlock ingestion, and even encompassing lung transplantation following fume poisoning (multiple-18, methanol-12, CO-9, cyanide-5, organophosphate-3, ethylene glycol-3, brodifacoum-2, carbamate-2, ethanol-1, hydrogen sulphide-1, nicotine-1, fume-1, doxepin-1, paraquat-1, hemlock-1, cocaine-1, ecstasy-1, acetaminophen-1 amanita phalloides-1, and trimipramine-1). …”
Get full text