Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions by Martin Škandík, Lara Friess, Guillermo Vázquez-Cabrera, Lily Keane, Kathleen Grabert, Mireia Cruz De los Santos, Mercedes Posada-Pérez, Austeja Baleviciute, Mathilde Cheray, Bertrand Joseph

“…Microglial purine sensing and motility capacities, regulated by P2RY12/P2RY13, displayed age-related alterations. …”
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Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study by Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y

“…Shan Xiao,1,&ast; Jie Ou,2,&ast; Wangli Qiu,3,&ast; Chunxin Ye,1 Na Li,1 Sida Chen,1 Yuting Lai,1 Zhishan Deng,4 Fan Wu,4 Yan Shen1 1Department of Pulmonary and Critical Care Medicine, Shenzhen Longgang District Central Hospital, Shenzhen, People’s Republic of China; 2State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, People’s Republic of China; 4State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yan Shen, Email drshenyan2022@163.com Fan Wu, Email wu.fan@vip.163.comBackground: Preserved ratio impaired spirometry (PRISm) is defined as forced expiratory volume in one second (FEV1)/forced vital capacity (FVC)≥ 0.70 and FEV1< 80% predicted. Previous studies have shown that individuals with PRISm may develop airflow obstruction and have an increased mortality risk. …”
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Mechanism of Exogenous Silicon in Enhancing Cold Stress Tolerance in <i>Solanum lycopersicum</i> L. Seedlings: Insights from Resistance and Quality Indicators by Fan Zhang, Yihong Zhao, Yuanbo Zhang, Yu Shi, Leiping Hou, Abid Khan, Ruixing Zhang, Yi Zhang

“…Moreover, it significantly ameliorated the osmotic adjustment and antioxidant capacity of the plants, thereby alleviating the low-temperature stress. …”
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Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Three variables were evaluated: 1) Bite Force (BF) (measured in Newtons – N) presented as the average of the bite force from the right and left molars (x‾ RM + LM), using a gnathodynamometer (IDDK Kratos), 2) Masticatory Efficiency (ME) (ranging from 0 to 1, with values closer to 1 indicating poorer efficiency), assessed through a dual-color masticatory gum test analyzed visually and optoelectronically (ViewGum©), and 3) Masticatory Capacity (MC): patient-reported ability to chew, rated on a two-point scale (P/R = poor to reasonable, G/O = good to optimal). …”
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Construct validity and responsiveness of clinical upper limb measures and sensor-based arm use within the first year after stroke: a longitudinal cohort study by Johannes Pohl, Geert Verheyden, Jeremia Philipp Oskar Held, Andreas Ruediger Luft, Chris Easthope Awai, Janne Marieke Veerbeek

“…Using clinical measures, upper limb motor function (Fugl-Meyer Assessment), capacity (Action Research Arm Test, Box & Block Test), and perceived performance (14-item Motor Activity Log) were assessed. …”
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Effect of the cervical and thoracic “Daoyin” training on posture and pulmonary function in patients with upper crossed syndrome: a randomized controlled trial by Yue Guo, Ming Li, Chaowei Xie, Xiaoyan Liu, Yushan Chen, Jun Yang, Yuxue Wu, Shaoqing Chen, Shizhong Wang, Jianping Lin

“…There were significant differences of the change values between groups in Forward Head Angle (FHA) (d = 1.113, P < 0.001), Forward Shoulder Angle (FSA) (d = 1.052, P < 0.001), VAS (d = 0.854, P < 0.001), NDI (d = 0.754, P = 0.005), pulmonary function (Forced Expiratory Volume in 1 s/Forced Vital Capacity (FEV1/FVC) (d = 0.516, P = 0.002), maximal voluntary ventilation (MVV) (d = 0.504, P = 0.033), cervical range of motion in Left Rotation (LR) (d = 0.647, P = 0.014) and emotional state (d = 0.587, P = 0.014). …”
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Prospects for the Use of Quasi-Mersen Numbers in the Design of Parallel-Serial Processors by Aruzhan Kadyrzhan, Kaisarali Kadyrzhan, Akhat Bakirov, Ibragim Suleimenov

“…It is shown that a serial-parallel processor, comparable in bit capacity to a 16-bit binary processor, can be implemented based on an algorithm built on the residue number system, a distinctive feature of which is the use of the first four quasi-Mersenne numbers, i.e., prime numbers representable as <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>p</mi><mi>k</mi></msub><mo>=</mo><msup><mn>2</mn><mi>k</mi></msup><mo>+</mo><mn>1</mn><mo>,</mo><mo> </mo><mi>k</mi><mo>=</mo><mn>1</mn><mo>,</mo><mn>2</mn><mo>,</mo><mn>3</mn><mo>,</mo><mn>4</mn></mrow></semantics></math></inline-formula>. …”
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Association between the composite dietary antioxidant index and non-alcoholic fatty liver disease: evidence from National Health and Nutrition Examination Survey 2005–2016 by Yidian Fu, Yidian Fu, Chao Jiang, Zonglin Li, Xiangyun Shi, Peiyuan Lv, Peiyuan Lv, Jingbo Zhang

“…Antioxidants from food can reduce NAFLD incidence, and the Composite Dietary Antioxidant Index (CDAI) measures total antioxidant capacity (TAC). However, the relationship between CDAI and NAFLD in the US adult population remains unclear.ObjectiveTo assess whether CDAI is associated with NAFLD in US adults.Design, setting, and participantsThis population-based cross-sectional study used data on US adults from the National Health and Nutrition Examination Survey (NHANES) 2005–2016 cycles. …”
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A perinatal psychiatry access program to address rural and medically underserved populations using telemedicine by Courtney King, Marie Hayes, Lizmarie Maldonado, Elizabeth Monter, Rubin Aujla, Erin Phlegar, Claire Smith, Liz Parker, Kerry Blome, Amanda Sandford, Edie Douglas, Constance Guille

“…Perinatal Psychiatry Access Programs have emerged as a successful model to increase the capacity of front-line maternal health care providers to address perinatal mental health conditions through education, consultation, and increased resources and referrals. …”
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Diseño tecnológico de un lugar de culto: valor histórico y constructivo = Technological design of a worship place: historical and constructive value by Antonella Violano, Antonio Maio

“…Al analizar las características arquitectónicas e históricas de un edificio, los diseñadores son capaces de identificar la calidad formal y material de la arquitectura, así como el poder creativo vinculado al genius loci, o espíritu del lugar. …”
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L’emploi antique des géomatériaux à Reims/Durocortorum by Gilles Fronteau, Sébastien Laratte, Alain Devos, Claire Pichard

“…Thus, the use of geomaterials can be understood as responding just as much to a logic of availability or accessibility, as to a capacity for implementation or requirements in terms of quality, as illustrated by the use of stones with low capillary action in foundations or stem-walls. …”
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Scoping review of costs of implementation strategies in community, public health and healthcare settings by Hongmei Wang, Jungyoon Kim, Tzeyu L Michaud, Emiliane Pereira, Gwenndolyn Porter, Caitlin Golden, Jennie Hill, Cindy Schmidt, Paul A Estabrooks

“…Objectives To identify existing evidence concerning the cost of dissemination and implementation (D&amp;I) strategies in community, public health and health service research, mapped with the ‘Expert Recommendations for Implementing Change’ (ERIC) taxonomy.Design Scoping review.Data sources MEDLINE, EMBASE, CINAHL, PsycINFO, Scopus and the Cochrane Library were searched to identify any English language reports that had been published between January 2008 and December 2019 concerning the cost of D&amp;I strategies.Data extraction We matched the strategies identified in each article using ERIC taxonomies; further classified them into five areas (eg, dissemination, implementation, integration, capacity building and scale-up); and extracted the corresponding costs (total costs and cots per action target and per evidence-based programme (EBP) participant). …”
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Analisis Kinerja Algoritme TCP Congestion Control Berdasarkan Single dan Multiple Flow pada Multi-Path Routing by Bayu Sutawijaya, Achmad Basuki, Fitra Abdurrachman Bachtiar

“…Abstract The multi-path routing technique is an effective solution to increase network bandwidth capacity. However, TCP uses multiple paths similar to a single path. …”
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East Asian Welfare Regimes 東アジア福祉制度 by Joseph Wong, Andrew DeWit, Ito Peng

“…These latter countries are adopting this rather counterintuitive (considering the “Asian values” culturalist emphasis on communitarianism in East Asia) approach due to restricted fiscal capacity in the central state and the lack of credibility for communitarian ideology in what are highly diverse polities.All the countries in East Asia confront rapid ageing as well as the challenge from cheap labor in the other developing countries. …”
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Effect of adding concentrated myofibrillar proteins of silver carp (Hypophthalmichthys molitrix) on the qualitative and nutritional characteristics of pasta by Mahsa Karami Charvadeh, Eshagh Zakipour Rahimabadi, Parva Safari

“…In addition, the swelling index showed an increasing trend, displaying the effect of concentrated myofibrillar protein on the elevated water absorption rate and water retention capacity during the cooking processes. Conclusion: Given the results of sensory analysis with chemical characteristics and quality characteristics of cooking the pasta, it can be concluded that enrichment with up to 10% concentrated myofibrillar fish proteins makes no difference compared to the control group, while enhancing the desired characteristics of the final product.…”
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Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…., housing vouchers) (2) Key clinician-level factors such as capacity for unscheduled peer-facilitated appointments, having dedicated time for case consults with peers, and clinicians trained in working with PWUD and skilled in identifying related clinical concerns (3) Key systems-level elements such as standing lab orders, challenges related to specialty pharmacies and Medicaid managed care organizations, and streamlined communication strategies between peers and clinicians. …”
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An early lung cancer diagnosis model for non-smokers incorporating ct imaging analysis and circulating genetically abnormal cells (CACs) by Ran Ni, Yongjie Huang, Lei Wang, Hongjie Chen, Guorui Zhang, Yali Yu, Yinglan Kuang, Yuyan Tang, Xing Lu, Hong Liu

“…Validation revealed that these models exhibited excellent discrimination and calibration capacities, especially the first model built using the RF method, suggesting their clinical utility in the early screening and diagnosis of non-smoking LC.…”
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Complex Study of Settlements Dating from the Paleolithic to Medieval Period in the Ural Mountains on the Border of Europe and Asia by Valentina Prikhodko, Nikita Savelev, Vyacheslav Kotov, Sergey Nikolaev, Evgeny Ruslanov, Mikhail Rumyantsev, Elena Manakhova

“…Due to the above properties, chernozems have a high buffering capacity and a strong bond with heavy metals. Therefore, no inhibition of microbes was observed. …”
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A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…Hydroxyl radical and reactive oxygen species generation capacities were quantified. Cellular studies using B16F10 cells assessed cytotoxicity, cellular uptake, migration inhibition, and colony formation suppression. …”
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The Thermal Tolerance of Springtails in a Tropical Cave, with the Description of a New <i>Coecobrya</i> Species (Collembola: Entomobryidae) from Thailand by Nongnapat Manee, Louis Deharveng, Cyrille A. D’Haese, Areeruk Nilsai, Satoshi Shimano, Sopark Jantarit

“…This study is the first attempt that provide information on the impact of increasing temperature on the population dynamics, reproductive capacity and life history of a subterranean tropical Collembola.…”
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