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12901
Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors
Published 2025-01-01“…Abstract The monkeypox virus (MPXV), which is a member of the Orthopoxvirus genus in the class Poxviridae, is the causative agent of the zoonotic viral infection MPXV. …”
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12902
Utilizing MFCCs and TEO-MFCCs to Classify Stress in Females Using SSNNA
Published 2025-01-01“…This study utilized female speeches to detect and classify stress and no stress in women. Using speech, composed of non-invasive and non-intrusive approaches, helps to identify stress better in females. …”
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12903
Rnd3 protects against doxorubicin-induced cardiotoxicity through inhibition of PANoptosis in a Rock1/Drp1/mitochondrial fission-dependent manner
Published 2025-01-01“…Abstract Doxorubicin, a representative drug of the anthracycline class, is widely used in cancer treatment. However, Doxorubicin-induced cardiotoxicity (DIC) presents a significant challenge in its clinical application. …”
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12904
Short‐term echocardiographic evaluation by global longitudinal strain in patients with heart failure treated with sacubitril/valsartan
Published 2020-06-01“…Methods and results Thirty patients with New York Heart Association class II–III HFrEF were treated with ARNI and monitored using standard echocardiographic examination and GLS measurements at baseline, 3 months, and 6 months. …”
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12905
Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design
Published 2021-09-01“…CD28-based CD33CARTs consistently induced more robust inhibition of leukemia proliferation in AML cell line and PDX models than did 4-1BB-based CD33CARTs. A ‘best-in-class’ lintuzumab-CD28/CD3ζ CAR construct was thus selected for clinical translation.Conclusions CD33 is a critical antigen for potential immunotherapeutic targeting in patients with AML. …”
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12906
Genetic Nurture Effects on Type 2 Diabetes Among Chinese Han Adults: A Family-Based Design
Published 2025-01-01“…Five ontologies were identified as enrichment in both direct and indirect genetic effects, including flavonoid metabolic process and antigen processing and presentation via the MHC class Ib pathway. Two pathways were only enriched in paternal genetic nurture effects, including the transforming growth factor beta pathway. …”
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12907
Akin Ogundiran: The Historian and Archaeologist of Yoruba-Atlantic becomes Chancellor Professor at the University of North Carolina at Charlotte
Published 2021-12-01“…He was a graduate of Obafemi Awolowo University where he bagged BA in Archaeology (First Class Honors) in 1988. This is where and when our interactions began, and that was where we sensed he was a student who would be greater than his teachers. …”
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12908
The evaluation of internal adaptation of glass ionomer restorations applied after the use of different cavity conditioners in primary teeth: an in-vitro study
Published 2025-01-01“…Methods 80 extracted primary second molar teeth were randomly assigned to four different cavity conditioner groups [10% polyacrylic acid, 20% polyacrylic acid, 17% ethylene diamine tetraacetic acid (EDTA), 35% phosphoric acid]. Class V cavities were prepared on the buccal surfaces and relevant cavity conditioners were applied, and the samples in each cavity conditioner group were randomly assigned to glass hybrid (GHR) or conventional glass ionomer restoratives (CGIR). …”
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12909
Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study
Published 2022-06-01“…Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. …”
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12910
A ERGONOMIA E OS ASSENTOS DE AVIÃO: UM ESTUDO DO CONFORTO E BEM-ESTAR PARA O USUÁRIO
Published 2023-01-01“…Em pleno século XXI, os passageiros da classe econômica de voos comerciais ainda têm demonstrado um descontentamento para com as poltronas oferecidas pelas companhias aéreas. …”
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12911
Estimating ocean currents from the joint reconstruction of absolute dynamic topography and sea surface temperature through deep learning algorithms
Published 2025-01-01“…This modification allows us to evaluate the potential enhancement in the ADT and SST mapping while integrating dynamical constraints through tailored, physics-informed loss functions. The neural networks are thus trained using OSSE data and subsequently applied to the Copernicus Marine Service satellite-derived ADTs and SSTs, allowing us to reconstruct super-resolved ADTs and geostrophic currents at the same spatiotemporal resolution of the model outputs employed for the OSSE. …”
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12912
Das Ende der kolonialen Epoche im Himalaya
Published 2024-12-01“…An exceptional class of mountain people has emerged in recent years among the indigenous inhabitants of the highland regions of Asia. …”
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12913
Main threats to the state’s interests in the sphere of information security of Ukraine
Published 2024-03-01“…In order to eliminate the above threats, it is proposed to: develop a comprehensive legal act on the principles of information security of Ukraine, which would consolidate real and potential threats to information security, the foundations of the State policy in the field of information security, in particular under martial law, which would facilitate further development of this area, consistency of certain by-laws and regulations that partially regulate this area and lay down a strategic vision of its development; use the potential of modern information technologies in the process of disseminating information about real problems and needs at the grassroots level; convey to the international community the real, not artificially formed, moods and ideas of the population regarding certain problems related to patriotism and loyalty to the state; introduce information security education, which allows equipping the population with a set of necessary knowledge about the basics of critical thinking, information hygiene and media security; In order to eliminate the above threats, it is proposed to: develop a culture of information security by developing national strategies that would cover a set of educational, ideological, cultural activities, as well as different categories of the population, for example, developing a system of professional development for public servants, teaching certain disciplines for students of higher education institutions and holding classes, competitions, tournaments for students of general secondary education institutions.…”
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12914
Ascension du mont Blanc (4808 m) : quels risques prend-on dans le Grand Couloir du Goûter et dans la face nord du mont Blanc du Tacul ?
Published 2023-11-01“…Sur le premier site, où l'on déplore une très forte accidentalité avec en moyenne 3,7 décès par an, 17 768 passages ont été comptabilisés au cours de l’été 2019 et 2 648 signaux sismiques ont été classés comme des chutes de pierres ayant affecté le Grand Couloir. …”
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12915
Composition and the predicted functions of fungal communities and the key drivers in acidic soils of Jiaodong Peninsula, China
Published 2025-01-01“…Redundancy analysis (RDA) revealed that soil pH as well as nitrate nitrogen (NO3−-N) and total nitrogen (TN) significantly associated with fungal community at the phylum level, whilst soil pH was the only factor significantly linked to individual fungal classes (p < 0.01 or 0.05). The further Mantel test analysis and structural equation modeling (SEM) suggested that, in contrast to the negative and directive driving of soil pH on fungal communities' variation, the specific plant pathogenic fungi, Gibberella and Didymellaceae, were significantly and positively associated with soil acidic characteristics (p < 0.05).DiscussionThese findings highlighted that, in addition to modulating the variation of soil fungal community, soil acidification might prime some plant pathogens development. …”
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12916
Remimazolam for the prevention of emergence agitation in adults following nasal surgery under general anesthesia: a prospective randomized clinical controlled trial
Published 2025-01-01“…Abstract Background Remimazolam is a novel intravenous sedative/anesthetic drug that belongs to the ultra-short-acting class of benzodiazepines. The purpose of this study was to evaluate the effectiveness of postoperative use of remimazolam in preventing emergence agitation (EA) in adults following nasal surgery. …”
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12917
Identifying biomarker-driven subphenotypes of cardiogenic shock: analysis of prospective cohorts and randomized controlled trialsResearch in context
Published 2025-01-01“…Methods: We used unsupervised clustering to integrate plasma biomarker data from two prospective cohorts of CS patients: CardShock (N = 205 [2010–2012, NCT01374867]) and the French and European Outcome reGistry in Intensive Care Units (FROG-ICU) (N = 228 [2011–2013, NCT01367093]) to determine the optimal number of classes. Thereafter, a simplified classifier (Euclidean distances) was used to assign the identified CS subphenotypes in three completed randomized controlled trials (RCTs) (OptimaCC, N = 57 [2011–2016, NCT01367743]; DOREMI, N = 192 [2017–2020, NCT03207165]; and CULPRIT-SHOCK, N = 434 [2013–2017, NCT01927549]) and explore heterogeneity of treatment effect with respect to 28-day mortality (primary outcome). …”
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12918
Assessing coupling between soil temperature and potential air temperature using PALM-4U: implications for idealized scenarios
Published 2025-01-01“…We develop several scenarios, distinguishing between cyclic and <i>Dirichlet/radiation</i> boundary conditions along the <span class="inline-formula"><i>x</i></span> axis, between summer and winter, and between various land cover types. …”
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12919
The Readership of Books in Ireland, 1700-1800
Published 2005-01-01“…Cet essai se place du point de vue du lecteur en tant que centre du circuit de communication et se propose d’observer comment tous les autres processus se déterminent à partir de lui.En Irlande, le XVIIIe siècle fut l’époque où l’accès à l’éducation commença à s’élargir, et un nombre croissant de personnes issues des classes moyennes ou supérieures de la société étaient non seulement capables de lire, mais en avaient aussi l’occasion.En s’appuyant sur les listes d’abonnements et sur les informations sur leur provenance contenues dans les livres, il est possible d’identifier ces lecteurs, et à travers des journaux intimes, des lettres ou des récits personnels, de se faire une idée du type de réactions suscitées par les textes chez leurs lecteurs. …”
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12920
Oral microbiocenosis state under different approaches of replacing dental crown defects
Published 2024-10-01“…Using disks with phenylboronic acid, ethylenediaminetetraacetic acid and cloxacillin, it was established that Klebsiella spp. were producers of class A carbapenemases (n=3) and contained AmpC (n=3). …”
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