The pattern of antibiotic utilisation among intensive care unit patients hospitalised in a Gauteng (South African) provincial tertiary hospital: Comparing findings before and durin... by L Spinickum, Z Booth, S Leigh-de Rapper

“…Methods. A retrospective cross-sectional data analysis was undertaken of 335 medical files of ICU patients hospitalised in a GPTH between January 2017 and December 2021. …”
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Geomorphic imprint of high-mountain floods: insights from the 2022 hydrological extreme across the upper Indus River catchment in the northwestern Himalayas by A. Kashyap, K. L. Cook, M. D. Behera

“…The flood-affected regions had high mean basin <span class="inline-formula"><i>k</i>_sn</span> (normalized steepness index) values and stream length–gradient (SL) index values, with numerous spikes in their magnitudes along their channel profiles downstream. …”
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Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“… # Summary TRD is associated with huge costs on individual and societal levels. Underlying disease processes are multifactorial and not well understood. …”
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Test-Retest Reliability and Validity of TecnoBody D-Wall to Assess the Range of Motion During Overhead Squat in Healthy Individuals by Caglar Soylu, Gorkem Acar, Berkay Uzumcu, Pervin Demir, Sinan Seyhan, Turker Biyikli

“…The results demonstrated excellent agreement between the two systems, with intra-class correlation coefficients (ICC) ranging from 0.79 to 0.99. …”
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Omeprazole: Inhibiting the Final Common Pathway to Acid Secretion - The Acid Pump by A.B.R. Thomson

“…Omeprazole is the first agent in a new therapeutic advance class the proton or acid pump inhibitors which represents a significant therapeutic advance in the treatment of acid related diseases. …”
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Mechanisms and thresholds of land use affecting surface water quality in Hangzhou City’s residential areas by Qianhu Chen, Jinye Huang

“…However, we can successfully control this negative impact by increasing the degree of green space dominance and aggregation. (3) To meet the standards for Class III water quality, various types of residential areas must adopt distinct control indicator thresholds: Compared to multi-story residential areas’ dispersed green spaces, small high-rise residential areas feature highly interconnected and clustered green spaces, which increases surface runoff pooling and spillover. …”
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Le chemin des « mauvaises filles » by Véronique Blanchard, Hélène Duffuler-Vialle

“…The second part of the exhibition takes the public to a locked room where big photographs and copies of imprisoned girls’ words show the effect of confinement throughout the ages.The aim or the exhibition is tolerance and humanism. …”
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Une étude des discours et des actions d’aide de six professeurs des écoles auprès d’élèves « peu performants » en mathématiques by Marie Toullec-Théry

“…Trois des professeurs étudiés enseignent en classe « ordinaire », trois autres, maîtres spécialisés à dominante pédagogique (maîtres E), travaillent exclusivement avec des groupes d’élèves présentant des difficultés d’apprentissage. …”
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Urban Economic Structures as Multidimensional Networks: A Complex Systems Framework for Analyzing Economic Development Trajectories by Shade T. Shutters

“…Yet different types of entities also exhibit colocation patterns with each other, such as patent technology classes and industries. Here, those cross-entity colocation patterns are used to merge multiple types of entities into a single network representation of urban economies, offering a granularity not possible using a single node type. …”
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Validity and reliability of the brief form of the normative male alexithymia scale among Chinese patients after radical prostatectomy by F. Wang, X. Zhang, L. Huang, X. Zhang, W. Jie, X. Chang, Y. Chu, L. Wang, W. Jia, B. Zhang

“…The Cronbach’s alpha coefficient for the Chinese version of the NMAS-BF was 0.856. The intra-class correlation coefficient (ICC) for the total scale was 0.938, indicating good stability. …”
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Differential use of multiple food sources at a bathyal benthic ecosystem in the central Sagami Bay revealed by amino acid nitrogen isotopic compositions by Hidetaka Nomaki, Yoshito Chikaraishi, Nanako O. Ogawa, Koh Maki, Motohiro Shimanaga, Hisami Suga, Masashi Tsuchiya, Toshi Nagata, Naohiko Ohkouchi

“…Despite living in the same habitat, organisms of these two size classes may belong to independent food webs due to differences in feeding ecology.…”
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A General Framework for Closed Loop Negative Feedback Multivariable Physiological Control Systems: Existence, Uniqueness, and Stability of Homeostatic Equilibrium Points by Anna Procopio, Annarita Tedesco, Fabrizio Lo Regio, Giuseppe Cesarelli, Leandro Donisi, Carlo Ricciardi, Alessio Merola, Alfonso Maria Ponsiglione, Maria Romano, Francesco Montefusco, Carlo Cosentino, Francesco Amato

“…In this context, the present work proposes a general framework to model the dynamics and describe the behavior of a wide class of multivariable physiological control systems, from the molecular to the whole-organ scale. …”
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Breakthrough Psoriasis in Patients Receiving Biologicals by Damsin T, Absil G, Libon F, Tassoudji N, Nikkels AF

“…In none of the cases, there was a consistency between the breakthrough event and the next scheduled injection, nor the duration of the exposure to the treatment. No biological class or agent could be systematically incriminated.Conclusion: Breakthrough psoriasis is an exceptional event among patients with stabilized psoriasis using biologicals, either triggered by the Köbner phenomenon or by severe psychological stress. …”
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Disruption of zinc homeostasis reverses tigecycline resistance in Klebsiella pneumoniae by Jinyu Wang, Jinyu Wang, Cuiping Xia, Cuiping Xia, Zhaoxin Xia, Zhaoxin Xia, Jilu Shen, Jilu Shen

“…These results highlight the potential of zinc ionophores as a novel class of antimicrobial agents and warrant further investigation into their clinical applications.…”
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Metabolic profiling of Perilla leaves of different colors: insights into metabolite variation and bioactive compound distribution by Senouwa Segla Koffi Dossou, Qianchun Deng, Feng Li, Lei Wang, Nanjun Jiang, Habtamu Kefale, Rong Zhou, Donghua Li, Meilian Tan, Linhai Wang

“…Amino acids and derivatives (15.50%), flavonoids (14.77%), phenolic acids (12.19%), lipids (9.60%), carbohydrates and derivatives (8.47%), organic acids and derivatives (7.99%), nucleotides and derivatives (7.99%), and terpenoids (5.25%) were the major classes of metabolites in perilla leaves. In contrast to green leaves, the principal component analysis and correlation analysis revealed a considerable influence of genotypes for the variation in purple leaves’ metabolite profiles. …”
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Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

“…Subgroup analysis did show an increased risk of UTI with dapagliflozin only (RR 1.21; 95% CI 1.02 to 1.43, I2=0.0%), but no other analysis supported an increased risk of AKI, DKA, UTI or fracture.Conclusions Current evidence from RCTs does not suggest an increased risk of harm with SGLT2 inhibitors as a class over placebo or active comparators with respect to AKI, DKA, UTI or fracture. …”
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The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada by Porjai Rattanapanadda, Porjai Rattanapanadda, Dana Ramsay, Alyssa Butters, Calvin W. Booker, Sherry J. Hannon, Steve Hendrick, Joyce Van Donkersgoed, Brian N. Warr, Sheryl P. Gow, Paul S. Morley

“…Resistance to ≥3 antimicrobial classes was detected in 2.4% of M. haemolytica, 3.4% of H. somni, and 21.3% of P. multocida isolates. …”
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Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation by Anis Adibah Osman, Siok-Fong Chin, Lay-Kek Teh, Noraidatulakma Abdullah, Nor Azian Abdul Murad, Rahman Jamal

“…Results: A total of 85 significantly differentially expressed metabolites (p-value <0.05; −1.5 < FC > 1.5) were identified between the lean and the obese individuals, with the lipid class being the most prominent. A stepwise logistic regression revealed three metabolites associated with increased risk of obesity (14-methylheptadecanoic acid, 4′-apo-beta,psi-caroten-4'al and 6E,9E-octadecadienoic acid), and three with lower risk of obesity (19:0(11Me), 7,8-Dihydro-3b,6a-dihydroxy-alpha-ionol 9-[apiosyl-(1->6)-glucoside] and 4Z-Decenyl acetate). …”
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Isolation and Identification of Staphylococcus aureus from Milk and Milk Products, Associated Factors for Contamination, and Their Antibiogram in Holeta, Central Ethiopia by Endrias Zewdu Gebremedhin, Addisu Bedashu Ararso, Bizunesh Mideksa Borana, Kebede Abdisa Kelbesa, Nega Desalegn Tadese, Lencho Megersa Marami, Edilu Jorga Sarba

“…All isolates are resistant to at least two classes of antimicrobial drugs, while 65.0% of the isolates were found to be multidrug-resistant. …”
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A durability- based design approach for structural applications with advanced cement-based materials by Francesco Soave, Liberato Ferrara

“…This structure can benefit from a performance-based durability-design tailored to the use of high-performance construction materials since the retaining tank walls are exposed to a highly aggressive environment: both XA and XD exposure classes, as per EN206 can be considered since the water is characterized by high concentration of chlorides and sulphates. …”
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