PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…ICI may trigger allograft rejection, but the absolute risk of AR between the different ICI classes remains to be defined.MethodsVigiBase® (WHO’s pharmacovigilance database) was queried for reports of AR involving CTLA4, PD1, or PDL1 inhibitors. …”
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Les monolingues parlent aux bilingues : Plurilinguisme et parole politique aux États-Unis et au Canada by Charles Brasart

“…In Canada, relationships between linguistic communities raise questions as well, in so far as bilingualism may be perceived as a class privilege by English-speakers and as a threat by French-speakers.…”
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Optimal recovery of operators in sequence spaces by V.F. Babenko, N.V. Parfinovych, D.S. Skorokhodov

“…In this paper we solve the problem of optimal recovery of the operator $A_\alpha x= (\alpha_1x_1,\alpha_2x_2,\ldots)$ on the class $W^T_q = \{(t_1h_1,t_2h_2,\ldots)\,:\,\|h\|_{\ell_q}\le 1\}$, where $1\le q < \infty$ and $t_1\ge t_2\ge \ldots \ge 0$, and $\alpha_1t_1\ge\alpha_2t_2\ge\ldots\ge 0$ are given, in the space $\ell_q$. …”
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The Effects of Various Restorative Techniques on the Fracture Resistance of Pulpotomized Permanent Premolars by Yasamin Ghahramani, Fereshteh Shafiei, Zahra Jowkar, Sepideh Kazemian

“…The teeth in group 1 did not receive any preparation. Class II MOD cavities were prepared in the other experimental groups. …”
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Trends and socioeconomic inequalities of recommended antenatal care services utilization in Ethiopia: A decomposition analysis using Ethiopian nationwide Demographic Health Surveys... by Yawkal Tsega, Abel Endawkie, Gebeyehu Tsega, Asnakew Molla Mekonen, Yeshimebet Ali Dawed, Chad Stecher

“…<h4>Conclusion</h4>The study revealed that Ethiopian women's utilization of recommended ANC services was unequal by their socioeconomic classes, with better off women more likely to utilize the recommended ANC services than worse off women. …”
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Deep Learning Based Dual Channel Banana Grading System Using Convolution Neural Network by Raghavendra S, Souvik Ganguli, P. Thirumarai Selvan, Mitali Madhusmita Nayak, Sushovan Chaudhury, Randell U. Espina, Isaac Ofori

“…Created system can be employed in the food processing business, in real-life applications where the intelligent system’s accuracy, cost, and speed will improve the production rate and allow satisfying consumer demand. …”
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The Reliability and Validity of a Novel Clinical Test for Assessing Shoulder Rotation ROM in Collegiate Baseball Players: Functional Assessment of System Tension of the Shoulder (F... by Steven Dischiavi, Jesse Perry, Connor Burk, Jeremy Chiang, Chris Bleakley

“… # Study Design Reliability and validity analysis # Methods A study with 49 healthy participants (31 collegiate baseball players, 18 controls) examined a sport specific shoulder rotation PROM test (FAST-SHDR) and compared this to the standard supine 90/90 shoulder in a single session assessment. Intra-class correlation coefficient (ICC), standard error of measurement (SEM) and minimum detectable change (MDC) were calculated. …”
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A arte da vida homotransexual em Damata na relação com a história dos afrodisias by Claudio Noel de Toni Junior

“… A singularidade do modo de vida dos sujeitos no dispositivo da sexualidade na obra de Damata, em plena ditadura militar, onde o território principal é a cidade do Rio de Janeiro, com as vivências de pessoas ligadas à Marinha do Brasil, traz à tona a questão das homossexualidades desta classe em especial, em diferentes tempos de suas vidas e na relação de gosto de ser ativo ou passivo, o que, sem citar a obra, surge na questão do gênero. …”
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Exposure of Mycobacteriodes abscessus clones to mucin affects bacterial phenotype by Amy Leestemaker-Palmer, Tiffany Ong, Luiz E Bermudez

“…The microorganisms are also resistant to a number of antibiotic classes, making treatment challenging. To begin understanding how the bacterium adapts to the lung environment, pure colonies of M. abscessus strain 19,977 were grown in 7H9 broth with or without mucin over 30-day intervals for 6 months and analyzed for colony morphology, 7 day-growth curves, the ability to form biofilms after 14 days, and the susceptibility to antibiotics determined using previous published methods. …”
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Academic and Socioсultural Adaptation of Students in Russian Universities by P. A. Ambarova, G. E. Zborovsky, V. S. Nikolskiy, N. V. Shabrova

“…The total volume of the sample was 15,902 people, the maximum sampling error didn’t exceed 1%.Based on empirical data, the article shows the main problems of students’ adaptation to learning, namely, a significant amount of new information, the pace of the educational process, the format of practical classes and coursework that require more independence and activity than in school education. …”
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IN THE WAKE OF PUGACHEV’S REBELLION: EXPERIENCE IN ORAL HISTORY by N. V. Shevtsov

“…Thousands of people from different classes and nationalities joined rebellious Ural Cossacks in 1773. …”
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Metataxonomic Characterization of Enriched Consortia Derived from Oil Spill-Contaminated Sites in Guimaras, Philippines, Reveals Major Role of Klebsiella sp. in Hydrocarbon Degrada... by Kiara Nicole D. Rodriguez, Russel T. Santos, Michael Joseph M. Nagpala, Rina B. Opulencia

“…Overall, the amplicon sequence variants (ASVs) retrieved were mainly from the Gammaproteobacteria class, in which many hydrocarbon-degrading bacteria are found. …”
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Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus by A. L. Matveev, Ya. A. Khlusevich, I. K. Baykov, I. V.  Babkin, E. P. Goncharova, V. V. Morozova, N. V. Tikunova

“…To develop a stable strain, the cassette vector plasmid pCDNA5/FRTDHFR­CH­CL containing the site of homologous recombination and the genes encoding heavy and light chains of the fully human antibody of the IgG1/kappa class was constructed at the first step. Notably, DNA of the plasmid pCDNA5/FRT­DHFR­CH­CL was organized in such a way that the restriction sites for rapid cloning of DNA fragments encoding the variable domains of heavy and light chains were inserted upstream of the sequences encoding constant domains of the heavy and light chains of the antibody. …”
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Multi-dimensional outcomes following extracorporeal cardiopulmonary resuscitation by Tharusan Thevathasan, Vanessa Wahl, Joshua Boettel, Megan Kenny, Julia Paul, Sophie Selzer, Abdulla Al Harbi, Eva-Maria Dorsch, Heinrich Audebert, Matthias Rose, Christoph Paul Klapproth, Sonia Lech, Katharina Schmitt, Steffen Desch, Ulf Landmesser, Ralf Westenfeld, Fabian Voss, Carsten Skurk

“…Many patients reported dizziness or dyspnea (>52%) during daily activities, with a median New York Heart Association class of 2, EQ-5D-5L score of 53 and elevated NT-proBNP levels. …”
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Geology of the Tabakoto gold deposit, Kédougou-Kéniéba Inlier, West African Craton, Mali by Diallo Mahamadou, Salvi Stefano, Baratoux Lenka, Béziat Didier, Vanderhaeghe Olivier, Labou Ibrahima, Baratoux David, Ly Saïdou

“…The Tabakoto gold deposit is part of the highly endowed west-Malian gold belt, which hosts several world-class deposits. Located in the Paleoproterozoic Kédougou-Kéniéba Inlier (KKI) of the West African Craton (WAC), the deposit is contained in Birimian metasedimentary rocks of the Kofi series that are intruded by magmatic dikes. …”
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HPRS: hierarchical potential-based reward shaping from task specifications by Luigi Berducci, Edgar A. Aguilar, Dejan Ničković, Radu Grosu

“…Through ablation studies, we analyze the impact of individual requirement classes on emergent behavior. Our experiments show that HPRS benefits from comfort requirements when aligned with the target and safety and ignores them when in conflict with the safety or target requirements. …”
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Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings by Lili Ma, Lizhong Ma, Yu Yang, Ting Chen, Limin Wang, Qilong Deng

“…Our in vitro results showed that miR-34a-3p might promote the in vitro differentiation of neural stem cell (NSC) through suppressing PDCD6 and regulating other important neural markers such as fibroblast growth factor receptor 1 (FGFR1), MAP1/2 (MAP kinase kinases 1/2), myelin basic protein (MBP), βIII-tubulin Class III β-tubulin (βIII tubulin), and glial fibrillary acidic protein (GFAP). …”
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Genomic assessment of targets implicated in Rhipicephalus microplus acaricide resistance. by Christina Meiring, Michel Labuschagne

“…The identified mutations, both previously reported and novel, were compared between acaricide-susceptible and acaricide-resistant isolates, phenotypically characterized using the larval packet test or larval immersion test across five acaricide classes. Genotypes were then correlated with available phenotypes, and protein modelling of novel nonsynonymous mutations was conducted to assess their potential impact on acaricide resistance. …”
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Implementation of the Project “Community Police Officer”: Real Actions to Bring Police Service Closer to People (on the example of Kharkiv oblast) by M. V. Holub

“…The author has suggested appropriate measures for more effective promotion of this project, in particular: to initiate for the Department of the National Police of Ukraine to take measures aimed at creating a legal base that can ensure the effective operation of community police officers according to the legal point of view, as well as their interaction with other law enforcement agencies, introducing relevant amendments into existing regulatory documents; to prepare propositions in regard to these provisions; to develop routes and time of foot patrol by community police officers of the assigned territory, taking into account the analysis of street offenses, the location of places visited by a significant number of residents of the united territorial communities and other features of a particular united community; to make propositions for the creation of a “basic” united territorial communities in Kharkiv oblast, in terms of community police officers’ activities, to initiate and provide assistance to the Department of Preventive Activities of the Main Directorate of the National Police in Kharkiv oblast in organizing and conducting practical classes with this category of employees with visiting the specified united territorial communities; to introduce training of community police officers on the basis of Kharkiv National University of Internal Affairs, to prepare appropriate educational and methodical material; to improve the work of community police officers to ensure effective exchange of information, opportunities to quickly make decisions in case of complications, create an Internet group in the application “Telegram”, which should include police officers working within the pilot project “Community Police Officer”.…”
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Soluble ST2 protein as a new biomarker in patientswith precapillary pulmonary hypertension by Marta Banaszkiewicz, Arkadiusz Pietrasik, Szymon Darocha, Michał Piłka, Michał Florczyk, Anna Dobosiewicz, Piotr Kędzierski, Ewa Pędzich-Placha, Janusz Kochman, Grzegorz Opolski, Adam Torbicki, Marcin Kurzyna

“…All patients were evaluated for World Health Organization (WHO) functional class (FC), N-terminal prohormone B-type natriuretic peptide (NT-proBNP), troponin T (TnT), and hemodynamics. …”
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