HDAC10 and its implications in Sézary syndrome pathogenesis by Monika Pieniawska, Karolina Rassek, Bogumiła Skwara, Magdalena Żurawek, Iwona Ziółkowska-Suchanek, Lydia Visser, Monique Lodewijk, Małgorzata Sokołowska-Wojdyło, Małgorzata Sokołowska-Wojdyło, Berenika Olszewska, Roman J. Nowicki, Roman J. Nowicki, Tomasz Stein, Aleksandra Dańczak-Pazdrowska, Adriana Polańska, Marta Szymoniak-Lipska, Natalia Rozwadowska, Katarzyna Iżykowska

“…Recent genomic studies underscore the role of epigenetic modifiers in CTCL pathogenesis, prompting an investigation into HDAC10, a member of class IIb HDACs, in SS. HDAC10 was investigated in different cancers, revealing its involvement in cell cycle regulation, apoptosis, and autophagy, but its role in CTCL is unknown. …”
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Taxonomic composition and biodiversity of the gut microbiome from patients with irritable bowel syndrome, ulcerative colitis, and asthma by A. Y. Tikunov, A. N. Shvalov, V. V. Morozov, I. V. Babkin, G. V. Seledtsova, I. O. Voloshina, I. P. Ivanova, A. V. Bardasheva, V. V. Morozova, V. V. Vlasov, N. V. Tikunova

“…In the samples from patients with intestinal diseases (IBS and UC), an increase in the proportion of sequences of the Bacteroidetes type and a decrease in the proportion of sequences of the Clostridia class, as well as the Ruminococcaceae, but not Erysipelotrichaceae family, were found. …”
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Il Ruolo della Leadership Infermieristica in un’Organizzazione Etica e Sostenibile by Sipontina Rita Zerulo, Maria Romilda Filice, Chiara Maddalo, Angelo Pirreco, Federico Ruta, Davide Ulvieri, Bruno Cavaliere

“…La causa appare risiedere nella scarsa formazione al tema specifico della classe dirigente. CONCLUSIONE: Molti studi hanno analizzato il tema degli SDG in relazione ai professionisti infermieri. …”
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Enhancing furcation involvement classification on panoramic radiographs with vision transformers by Xuan Zhang, Enting Guo, Xu Liu, Hong Zhao, Jie Yang, Wen Li, Wenlei Wu, Weibin Sun

“…Results Among the evaluated models, the ViT model outperformed all others, achieving the highest precision (0.98), recall (0.92), and F1 score (0.95), along with the lowest cross-entropy loss (0.27) and the highest accuracy (92%). …”
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PECULIARITIES OF THE LATENT PERIOD OF PRUNUS MONGOLICA MAXIM. AND P. PEDUNCULATA (PALL.) MAXIM. by K. G. Tkachenko

“…The main bulk was  attributed to the V and IV classes of development. The laboratory  germination of seeds freed from endocarp was 100% for both  species. …”
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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…By targeting the 3<span class="inline-formula">^′</span>UTR region of genes, such as miRNA-211, miRNA plays a significant regulatory role in melanogenesis. …”
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Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database by Peiyang Cao, Qian Wang, Yan Wang, Qing Qiao, Liyuan Yan

“…ObjectiveThis study aims to analyze the adverse drug events (ADEs) associated with tolvaptan in the Food and Drug Administration Adverse Event Reporting System database from the fourth quarter of 2009 to the second quarter of 2024.MethodsAfter standardizing the data, various signal detection techniques, including Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network, and Multi-Item Gamma Poisson Shrinker, were employed for analysis.ResultsAmong the 7,486 ADE reports where tolvaptan was the primary suspected drug, a total of 196 preferred terms were identified, spanning 24 different system organ classes. Specifically, hepatobiliary disorders, renal and urinary disorders, and metabolic and nutritional disorders were found to be characteristic adverse reactions associated with tolvaptan. …”
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Intraoperative support of patients with infective endocarditis complicated by acute heart failure by H.B. Koltunova

“…All patients had NYHA class IV. Results. In the group with IE complicated by preoperative AHF, 72 patients (100.0 %) were brought into the operating room from the intensive care unit in a critical condition and underwent urgent surgery for vital signs. …”
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EVALUATION OF THE APPLICABILITY OF THE O.K.N.V.I. RESIST-5 AND THE KPC&MBL&0XA-48 DISK TESTS IN A ROUTINE MICROBIOLOGY LABORATORY by Stefana Sabtcheva, Sylvia Georgieva

“… Background: The global spread of carbapenemase-producing Enterobacterales (CPE) and the increasing emergence of clinical Enterobacterales harboring multiple carbapenemases of different molecular classes have prioritized the use of rapid molecular detection methods in routine microbiology laboratories. …”
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A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study by Alec Banner, Joseph Webb, Nigel Scrutton

“…This may be partially due to a disparity between academic and industrial focus, and a greater emphasis needs to be placed on economic feasibility at an earlier stage. Terpenoids are a class of compounds with diverse use across fuel, materials and pharmaceutical industries and can be manufactured biologically from the key intermediate mevalonate. …”
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Simulation of Fire Emergency Evacuation in a Primary School Based on Pathfinder Software by Mahdi Safari, Reza Afkhami, Mohammad Amerzadeh, Vida Zaroushani

“…Additionally, when simulating an evacuation with 170 fewer students, the total evacuation time decreased by 128 s, suggesting that adhering to recommended class size standards can enhance evacuation efficiency. …”
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Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system by Jingrong Yang, Mengfan You, Jingxin Wang, Rongfei Sun, Lili Han, Xiaonan Liu, Kaibin Niu, Kaidi Xing, Juanping Sun, Wenge Su, Yifei Wang

“…BackgroundArrhythmias are prevalent cardiac disorders with significant impacts on patient quality of life and mortality. Amiodarone, a class III antiarrhythmic agent, is widely used to manage both atrial and ventricular arrhythmias due to its efficacy in prolonging the cardiac action potential and its multiple antiarrhythmic properties. …”
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Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China by Xiaowu Jiang, Abubakar Siddique, Li Chen, Lexin Zhu, Haiyang Zhou, Li Na, Chenghao Jia, Yan Li, Min Yue

“…Genotypic analysis of antimicrobial resistance identified 80 antimicrobial-resistant genes (ARGs), with mdf(A), aph(3′)-Ib, tet(A), dfrA12, floR, blaTEM-1B, qnrS3, and sul2, conferring resistance to different antimicrobial classes, being the predominant ARGs. Additionally, forty ESBL genes, particularly critical genes such as blaCTX-M and blaNDM-1, were also identified in Salmonella isolates. …”
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Psychotropic medications: a descriptive study of prescription trends in Tabriz, Iran, 2021–2022 by Mostafa Farahbakhsh, Ali Fakhari, Ali Azimian, Amin Khameneh, Mahsa Matinkia, Ehsan Aghajani

“…Antidepressants were the most commonly administered class, highlighting the need for training programs that specifically address their possible negative effects and the correct dosage. …”
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Effects of twelve-week aerobic exercise on selected health-related physical fitness variables on Gonji preparatory school male students by Abdurahman Esleman, Bizuneh Yirga Geberemariam, Wondiye Aychiluhim

“…The Control group had participated in regular physical education one class of  40-minute per week in the school, but the experimental group participated additional three sessions per week for 60 minutes aerobic exercise training program, which comprised walking, jogging, running, rope skipping, and aerobic dance. …”
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Signals of propaganda-Detecting and estimating political influences in information spread in social networks. by Alon Sela, Omer Neter, Václav Lohr, Petr Cihelka, Fan Wang, Moti Zwilling, John Phillip Sabou, Miloš Ulman

“…Together, they enable us to distinguish (p - value = 0.0001) between the two different classes of information cascades. In addition to constructing a bipartite graph connecting words and tweets to each cascade, we develop a quantitative measure and show how it can be used to distinguish between political and non-political discussions. …”
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Spatio-temporal Evolution of Land Surface Temperature and Its Response to LULC in the Urban Agglomeration of Central Yunnan by LIN Zhiqiang, PENG Shuangyun, SHI Shuangfu, HUANG Bangmei, MA Dongling, ZHU Ziyi, MA Xiaoliang, GONG Luping

“…[Results] (1) There were significant spatial and temporal differences in interannual temperature classes in central Yunnan urban agglomeration. The mesothermal area always occupied an absolutely dominant position (40%), but its area share decreased year by year. (2) From 1990 to 2020, the areas with UTFVI 0 showed an increasing trend year by year, and the areas with UTFVI > 0.02 showed a decreasing trend, and the ecological and thermal environments were gradually improved. (3) There were response differences in LST for different LULC types. …”
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Long-term changes in the dependence of <i>Nm</i>F2 on solar flux at Juliusruh by M. G. Tan Jun Rios, M. G. Tan Jun Rios, C. Borries, H. Liu, J. Mielich

“…A highly pronounced local time dependence in January with the <span class="inline-formula"><i>R</i>²</span> (goodness of the description for each fit) value being maximum around the noon hours has been observed. …”
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Addressing Label Noise in Colorectal Cancer Classification Using Cross-Entropy Loss and pLOF Methods With Stacking-Ensemble Technique by Ishrat Zahan Tani, Kah Ong Michael Goh, Md Nazmul Islam, Md Tarek Aziz, S. M. Hasan Mahmud, Dip Nandi

“…This system not only predicts the disease but also generates the prediction probabilities of each class, which enhances both clarity and diagnostic insight. …”
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Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins by Charles N. Serhan, Nan Chiang

“…Among them, lipoxins (LX) and aspirin-triggered LX (ATL) evoke actions of interest in a range of physiologic and pathophysiologic processes, and these two series have emerged as founding members of the first class of lipid/chemical mediators “switched on” in the resolution phase of an inflammatory reaction. …”
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