Drug utilization study of antiparkinsonian medication in Romania during 25 years by Camelia Bucsa, Denisa Bruhs, Anamaria Apan, Elena Francu, Cristina Mogosan, Irina Iaru

“…MAO-B inhibitors represented the second most used antiparkinsonian drug class for the majority of the years. Selegiline was the most used until 2017 (0.82 DDD/TID), when a decrease in use was observed and continued until 2022 (0.49 DDD/TID). …”
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Decreased sirtuin 1 in type 2 diabetes patients with abnormal BMD by Yao Xu, Tianxiao Hu, Peiwu Jiang, Xiujing Wang, Jiaqi Yao, Huiling Shen, Zhenying Zhang, Bojing Zheng, Ting Wang, Yanxia Ren, Jing Wang, Qingying Tan

“…IntroductionSirtuin 1, a class III histone deacetylase, plays a critical role in the pathophysiology of both diabetes mellitus and bone metabolism by promoting osteoblast differentiation and inhibiting osteoclast maturation. …”
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HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors by Xiaoyu Xi, Xiaona Zhang, Jianxin Tang, Xiumei Fan, Jiexian Du

“…HLA-DMB, the beta chain of the non-classical MHC class II protein HLA-DM, has been implicated in the progression of various cancers. …”
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Exploring practical experience with different treatments in NSCLC patients with MET-deregulated: a retrospective analysis from the real world by Mengmeng Li, Jiuyan Huang, Ruyue Xing, Xinyang Du, Chunhua Wei, Huijuan Wang

“…MET amplification patients benefit universally from targeted therapies; primary MET amplifications show higher benefits with increased copy numbers. For secondary MET amplifications post-EGFR-TKI resistance, dual-target therapy surpasses Crizotinib monotherapy, independent of MET copy number.…”
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Combining a Risk Factor Score Designed From Electronic Health Records With a Digital Cytology Image Scoring System to Improve Bladder Cancer Detection: Proof-of-Concept Study by Sandie Cabon, Sarra Brihi, Riadh Fezzani, Morgane Pierre-Jean, Marc Cuggia, Guillaume Bouzillé

“…This combination offers a higher associated risk of cancer than VisioCyt alone for all classes, especially for low-grade bladder cancer. …”
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Modulatory effect of Echium plantagineum oil on the n-3 LC-PUFA biosynthetic capacity of chicken (Gallus gallus) by Jesús Villora, José Antonio Pérez, Nieves Guadalupe Acosta, Deiene Rodríguez-Barreto, Pedro Juan Alonso, Mónica B. Betancor, Alexandr Torres, Sergio Álvarez, Covadonga Rodríguez

“…The dietary treatments did not affect the total lipid (TL) content (p>0.05) and did not substantially vary the lipid class (LC) profiles in the brain, liver, intestine, and muscle tissues. …”
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Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury by Chenyang Li, Chenyang Li, Yuchen Xu, Tao Feng, Tao Feng, Minmin Wang, Minmin Wang, Minmin Wang, Xiaomei Zhang, Li Zhang, Li Zhang, Ruidong Cheng, Weihai Chen, Weihai Chen, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang

“…Each filter paired with a support vector machine classifier to classify future movements into one of three classes: sit-to-stand, stand-to-sit, or rest. The final prediction was determined using a majority voting scheme.ResultsAmong the three functional connectivity methods investigated—coherence, Pearson correlation coefficient and mutual information (MI)—the MI-based EEG–EMG network showed the highest decoding performance (94.33%), outperforming both EEG (73.89%) and EMG (89.16%). …”
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Expectativas acerca das atividades síncronas na formação a distância do Programa Mais Médicos para o Brasil by Inara Pereira da Cunha, Sílvia Helena Mendonça de Moraes, Adriana Carvalho dos Santos, Débora Dupas Gonçalves do Nascimento

“…Resultados: A análise revelou cinco classes de palavras que representam as expectativas dos participantes. …”
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Burden of caregivers of older people in Sri Lanka: an overlooked concern in the health care system by Nirmala Rathnayake, Wedura Kannangara, Thilina Abeygunasekara, Warsha De Zoysa, Dhammika Palangasinghe, Sarath Lekamwasam

“…The test-retest reliability, assessed using the intra-class correlation coefficient, was 0.99 (95% CI: 0.99-1.00; p < 0.001). …”
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Prevalence of depression and its correlates among undergraduate health science students in Mogadishu, Somalia: a cross-sectional study by Bashiru Garba, Samiro Ali Mohamed, Maria Mowlid Mohamed, Hodo Aideed Asowe, Najib Isse Dirie, Yushau Umar, Jamal Hassan Mohamoud, Mohamed Hussein Adam, Jihaan Hassan, Fartun Abdullahi Hassan Orey, Abdullahi Abdirahman Omar, Ibrahim Abdullahi Mohamed, Mohamad Mustaf Ahmed, Samira Abdullahi Moalim

“…Simple random sampling based on class list was used to select the participants and a web-based self-administered Patient Health Questionnaire (PHQ-9) was used to screen for depression. …”
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Symptoms of dwarf elm (Ulmus pumila L.) health condition in the Left-bank Ukraine by Valentyna L. Meshkova, Olena A. Kuznetsova, Volodymyr P. Turenko

“…In this study, the data on 624 U. pumila trees in 11 sample plots were used, particularly, the diameter at breast height (DBH), the class of the health condition, defoliation, the prevalence of dry branches, epicormic shoots, bark beetle infestation, local bark death, and collar rots. …”
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Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…The participants were divided into two groups: 1) Cleft Lip and Palate Group (CLP): 20 adults with CLP undergoing orthognathic surgery (14 ♂, 6 ♀, age 24 ± 3 years), and 2) Control Group (CON): 20 paired adults with Angle Class I skeletal pattern who had never undergone orthognathic surgery (14 ♂, 6 ♀, age 25 ± 5 years). …”
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Efek Loading Statin Intensitas Tinggi Sebelum Intervensi Koroner Perkutan pada Pasien Sindrom Koroner Akut: Systematic Review by Cokorda Istri Padmi Suwari, Mutiara Claudia

“…<div class="WordSection1"><p><span data-preserver-spaces="true">Percutaneous Coronary Intervention (PCI) is one of the essential methods for Acute Coronary Syndrome (ACS) treatment, but this procedure has serious complications. …”
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Microstructures and Mechanical Properties of Al Matrix Composites Reinforced with TiO₂ and Graphitic Carbon Nitride by Chen Wang, Xianyong Zhu, Ke Zhang, Jiaan Liu, Xiong Xiao, Cheng Jiang, Jinyuan Zhang, Changchun Lv, Zhaoxue Sun

“…In situ phases can reduce the generation of coarse phases and improve interfacial bonding ability to enhance mechanical properties. …”
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Nationwide representative serosurvey of third-grade school children to evaluate the hepatitis B vaccination impact in Kyrgyzstan, 2022 by Michael Brandl, Gulnara Zhumagulova, Gulbara Ishenapysova, Zuridin Nurmatov, Tatiana Enverovna Kuchuk, Nurzhan Zamirbekova, Gulsunai Sattarova, Saikal Temirbekova, Zhanara Bekenova, Martyna Gassowski, Liudmila Mosina, Antons Mozalevskis, Sandra Dudareva, Siddhartha Sankar Datta

“…We applied multistage cluster sampling with school classes as clusters. Identified participants in the survey were tested for HBsAg, using Enzyme-linked Immunosorbent Assay (ELISA), and positive samples confirmed with neutralization tests. …”
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AICpred: Machine Learning-Based Prediction of Potential Anti-Inflammatory Compounds Targeting TLR4-MyD88 Binding Mechanism by Lucindah N. Fry-Nartey, Cyril Akafia, Ursula S. Nkonu, Spencer B. Baiden, Ignatus Nunana Dorvi, Kwasi Agyenkwa-Mawuli, Odame Agyapong, Claude Fiifi Hayford, Michael D. Wilson, Whelton A. Miller, Samuel K. Kwofie

“…To handle imbalance within the training data, resampling techniques such as random under-sampling, synthetic minority oversampling technique, and the random selection of 5000 instances of the majority class were employed. A 10-fold cross-validation strategy was used to evaluate model performance based on metrics including accuracy, balanced accuracy, and recall. …”
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Does Treatment with Sodium-Glucose Cotransporter-2 Inhibitors Affect Adherence to International Society Criteria for Diabetic Ketoacidosis in Adult Patients with Type 2 Diabetes? A... by Aongus O’Brolchain, Joshua Maletsky, Ibrahim Mian, Serena Edwards

“…The physiological effects of SGLT2i are such that hyperglycaemia and ketonuria are no longer reliable diagnostic tools in patients treated with this class of medication. Diagnostic criteria for DKA varies between major society guidelines. …”
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Impact of Oxycodone HCl Extended-release Formulary Restrictions on Extended-release Opioid Market Share, Healthcare Resource Utilization and Costs in Commercial and Medicare Plans by Rolin L. Wade, Chi-Chang Chen, Ajita P. De, Jaren C. Howard

“…**Background:** Previous research demonstrated that utilization management (UM) such as prior authorization (PA) or non-formulary (NF) restrictions may reduce pharmacy costs when designed and applied appropriately to certain drug classes. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…ObjectiveIn January 2023, China implemented the “Class B Management” policy, marking a new phase in COVID-19 control. …”
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PENGEMBANGAN DESAIN BAHAN AJAR FISIKA BERBASIS E-MODUL PADA MATERI MOMENTUM by Nadah Qolbi Shobrina, Indra Sakti, Andik Purwanto

“…This research was is a development research conducted in five stages, namely potention and problem, literature study and information gathering, product design, design validation, and tested design .The sample or data source of this research were the Physic Teacher and Student of SMAN 2 Bengkulu, class of X MIPA D. The instruments used in this research are observation sheet, teacher and student questionnaire, test questionnaire of expert team validation test. …”
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