Mechanisms and thresholds of land use affecting surface water quality in Hangzhou City’s residential areas by Qianhu Chen, Jinye Huang

“…However, we can successfully control this negative impact by increasing the degree of green space dominance and aggregation. (3) To meet the standards for Class III water quality, various types of residential areas must adopt distinct control indicator thresholds: Compared to multi-story residential areas’ dispersed green spaces, small high-rise residential areas feature highly interconnected and clustered green spaces, which increases surface runoff pooling and spillover. …”
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Urban Economic Structures as Multidimensional Networks: A Complex Systems Framework for Analyzing Economic Development Trajectories by Shade T. Shutters

“…Yet different types of entities also exhibit colocation patterns with each other, such as patent technology classes and industries. Here, those cross-entity colocation patterns are used to merge multiple types of entities into a single network representation of urban economies, offering a granularity not possible using a single node type. …”
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Differential use of multiple food sources at a bathyal benthic ecosystem in the central Sagami Bay revealed by amino acid nitrogen isotopic compositions by Hidetaka Nomaki, Yoshito Chikaraishi, Nanako O. Ogawa, Koh Maki, Motohiro Shimanaga, Hisami Suga, Masashi Tsuchiya, Toshi Nagata, Naohiko Ohkouchi

“…Despite living in the same habitat, organisms of these two size classes may belong to independent food webs due to differences in feeding ecology.…”
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A General Framework for Closed Loop Negative Feedback Multivariable Physiological Control Systems: Existence, Uniqueness, and Stability of Homeostatic Equilibrium Points by Anna Procopio, Annarita Tedesco, Fabrizio Lo Regio, Giuseppe Cesarelli, Leandro Donisi, Carlo Ricciardi, Alessio Merola, Alfonso Maria Ponsiglione, Maria Romano, Francesco Montefusco, Carlo Cosentino, Francesco Amato

“…In this context, the present work proposes a general framework to model the dynamics and describe the behavior of a wide class of multivariable physiological control systems, from the molecular to the whole-organ scale. …”
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Disruption of zinc homeostasis reverses tigecycline resistance in Klebsiella pneumoniae by Jinyu Wang, Jinyu Wang, Cuiping Xia, Cuiping Xia, Zhaoxin Xia, Zhaoxin Xia, Jilu Shen, Jilu Shen

“…These results highlight the potential of zinc ionophores as a novel class of antimicrobial agents and warrant further investigation into their clinical applications.…”
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Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis by Kris Aubrey-Bassler, John-Michael Gamble, Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen

“…Subgroup analysis did show an increased risk of UTI with dapagliflozin only (RR 1.21; 95% CI 1.02 to 1.43, I2=0.0%), but no other analysis supported an increased risk of AKI, DKA, UTI or fracture.Conclusions Current evidence from RCTs does not suggest an increased risk of harm with SGLT2 inhibitors as a class over placebo or active comparators with respect to AKI, DKA, UTI or fracture. …”
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The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada by Porjai Rattanapanadda, Porjai Rattanapanadda, Dana Ramsay, Alyssa Butters, Calvin W. Booker, Sherry J. Hannon, Steve Hendrick, Joyce Van Donkersgoed, Brian N. Warr, Sheryl P. Gow, Paul S. Morley

“…Resistance to ≥3 antimicrobial classes was detected in 2.4% of M. haemolytica, 3.4% of H. somni, and 21.3% of P. multocida isolates. …”
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Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation by Anis Adibah Osman, Siok-Fong Chin, Lay-Kek Teh, Noraidatulakma Abdullah, Nor Azian Abdul Murad, Rahman Jamal

“…Results: A total of 85 significantly differentially expressed metabolites (p-value <0.05; −1.5 < FC > 1.5) were identified between the lean and the obese individuals, with the lipid class being the most prominent. A stepwise logistic regression revealed three metabolites associated with increased risk of obesity (14-methylheptadecanoic acid, 4′-apo-beta,psi-caroten-4'al and 6E,9E-octadecadienoic acid), and three with lower risk of obesity (19:0(11Me), 7,8-Dihydro-3b,6a-dihydroxy-alpha-ionol 9-[apiosyl-(1->6)-glucoside] and 4Z-Decenyl acetate). …”
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Isolation and Identification of Staphylococcus aureus from Milk and Milk Products, Associated Factors for Contamination, and Their Antibiogram in Holeta, Central Ethiopia by Endrias Zewdu Gebremedhin, Addisu Bedashu Ararso, Bizunesh Mideksa Borana, Kebede Abdisa Kelbesa, Nega Desalegn Tadese, Lencho Megersa Marami, Edilu Jorga Sarba

“…All isolates are resistant to at least two classes of antimicrobial drugs, while 65.0% of the isolates were found to be multidrug-resistant. …”
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A durability- based design approach for structural applications with advanced cement-based materials by Francesco Soave, Liberato Ferrara

“…This structure can benefit from a performance-based durability-design tailored to the use of high-performance construction materials since the retaining tank walls are exposed to a highly aggressive environment: both XA and XD exposure classes, as per EN206 can be considered since the water is characterized by high concentration of chlorides and sulphates. …”
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Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…Abstract The monkeypox virus (MPXV), which is a member of the Orthopoxvirus genus in the class Poxviridae, is the causative agent of the zoonotic viral infection MPXV. …”
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Short‐term echocardiographic evaluation by global longitudinal strain in patients with heart failure treated with sacubitril/valsartan by Simone Mazzetti, Chiara Scifo, Raffaele Abete, Davide Margonato, Margherita Chioffi, Jessica Rossi, Matteo Pisani, Giovanni Passafaro, Massimiliano Grillo, Daniele Poggio, Andrea Mortara

“…Methods and results Thirty patients with New York Heart Association class II–III HFrEF were treated with ARNI and monitored using standard echocardiographic examination and GLS measurements at baseline, 3 months, and 6 months. …”
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

“…CD28-based CD33CARTs consistently induced more robust inhibition of leukemia proliferation in AML cell line and PDX models than did 4-1BB-based CD33CARTs. A ‘best-in-class’ lintuzumab-CD28/CD3ζ CAR construct was thus selected for clinical translation.Conclusions CD33 is a critical antigen for potential immunotherapeutic targeting in patients with AML. …”
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Genetic Nurture Effects on Type 2 Diabetes Among Chinese Han Adults: A Family-Based Design by Xiaoyi Li, Zechen Zhou, Yujia Ma, Kexin Ding, Han Xiao, Tao Wu, Dafang Chen, Yiqun Wu

“…Five ontologies were identified as enrichment in both direct and indirect genetic effects, including flavonoid metabolic process and antigen processing and presentation via the MHC class Ib pathway. Two pathways were only enriched in paternal genetic nurture effects, including the transforming growth factor beta pathway. …”
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Akin Ogundiran: The Historian and Archaeologist of Yoruba-Atlantic becomes Chancellor Professor at the University of North Carolina at Charlotte by Toyin Falola

“…He was a graduate of Obafemi Awolowo University where he bagged BA in Archaeology (First Class Honors) in 1988. This is where and when our interactions began, and that was where we sensed he was a student who would be greater than his teachers. …”
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Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study by Isabell Anna Just, Denis Fries, Sina Loewe, Volkmar Falk, Nikola Cesarovic, Frank Edelmann, Anna Feuerstein, Florian L. Haufe, Michele Xiloyannis, Robert Riener, Felix Schoenrath

“…Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. …”
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A ERGONOMIA E OS ASSENTOS DE AVIÃO: UM ESTUDO DO CONFORTO E BEM-ESTAR PARA O USUÁRIO by Ana Carolina Russo, Edison Russo, Carolina Machado Silberschimidt, Giuliana Mendes Montini, Juliana Blasbalg

“…Em pleno século XXI, os passageiros da classe econômica de voos comerciais ainda têm demonstrado um descontentamento para com as poltronas oferecidas pelas companhias aéreas. …”
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Estimating ocean currents from the joint reconstruction of absolute dynamic topography and sea surface temperature through deep learning algorithms by D. Ciani, C. Fanelli, B. Buongiorno Nardelli

“…This modification allows us to evaluate the potential enhancement in the ADT and SST mapping while integrating dynamical constraints through tailored, physics-informed loss functions. The neural networks are thus trained using OSSE data and subsequently applied to the Copernicus Marine Service satellite-derived ADTs and SSTs, allowing us to reconstruct super-resolved ADTs and geostrophic currents at the same spatiotemporal resolution of the model outputs employed for the OSSE. …”
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Das Ende der kolonialen Epoche im Himalaya by Anna Okopińska

“…An exceptional class of mountain people has emerged in recent years among the indigenous inhabitants of the highland regions of Asia. …”
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Main threats to the state’s interests in the sphere of information security of Ukraine by O. Yu. Starostin

“…In order to eliminate the above threats, it is proposed to: develop a comprehensive legal act on the principles of information security of Ukraine, which would consolidate real and potential threats to information security, the foundations of the State policy in the field of information security, in particular under martial law, which would facilitate further development of this area, consistency of certain by-laws and regulations that partially regulate this area and lay down a strategic vision of its development; use the potential of modern information technologies in the process of disseminating information about real problems and needs at the grassroots level; convey to the international community the real, not artificially formed, moods and ideas of the population regarding certain problems related to patriotism and loyalty to the state; introduce information security education, which allows equipping the population with a set of necessary knowledge about the basics of critical thinking, information hygiene and media security; In order to eliminate the above threats, it is proposed to: develop a culture of information security by developing national strategies that would cover a set of educational, ideological, cultural activities, as well as different categories of the population, for example, developing a system of professional development for public servants, teaching certain disciplines for students of higher education institutions and holding classes, competitions, tournaments for students of general secondary education institutions.…”
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