Assessment of IL-6 Pathway Inhibition in Gastrointestinal Behçet’s Disease from Immunological and Clinical Perspectives by Makoto Naganuma, Mitsuhiro Takeno, Aykut Ferhat Çelik, Robert Moots, Philippe Pinton, Tadakazu Hisamatsu

“…The selective inhibition of IL-6 trans-signaling may bring new impetus to the development of this drug class, particularly regarding safety. Still, the benefits of IL-6 inhibitors for patients with GIBD need to be evaluated in appropriate proof-of-concept studies. …”
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DFT Calculations and Molecular Docking Studies on a Chromene Derivative by Najet Aouled Dlala, Younes Bouazizi, Houcine Ghalla, Naceur Hamdi

“…Chromenes and their derivatives have been considered as an important class of oxygen-containing heterocycles. There has been an increasing interest in the study of chromenes due to their biological activity. …”
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Genetic Algorithms in Antennas and Smart Antennas Design Overview: Two Novel Antenna Systems for Triband GNSS Applications and a Circular Switched Parasitic Array for WiMax Applic... by Stylianos C. Panagiotou, Stelios C. A. Thomopoulos, Christos N. Capsalis

“…Genetic algorithms belong to a stochastic class of evolutionary techniques, whose robustness and global search of the solutions space have made them extremely popular among researchers. …”
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Efficient Probabilistic and Geometric Anatomical Mapping Using Particle Mesh Approximation on GPUs by Linh Ha, Marcel Prastawa, Guido Gerig, John H. Gilmore, Cláudio T. Silva, Sarang Joshi

“…In this paper, we present a solution based on two key ideas: a new registration method that generates a mapping between anatomies represented as a multicompartment model of class posterior images and geometries and an implementation of the algorithm using particle mesh approximation on Graphical Processing Units (GPUs) to fulfill the computational requirements. …”
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Optimal Control for a Family of Systems in Novel State Derivative Space Form with Experiment in a Double Inverted Pendulum System by Yuan-Wei Tseng, Jer-Guang Hsieh

“…The first step in deriving optimal control laws for SDS systems is to form an augmented cost functional. It turns out that novel differential Lagrange multipliers must be used to adjoin SDS system constraints (namely, the dynamical equations of the control system) to the integrand of the original cost functional which is a function of state derivatives. …”
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Emerging roles of circular RNAs on the regulation of production traits in chicken by Guishuang You, Hong Long, Xiaoxu Shen, Huadong Yin, Shibin Zhang

“…Circular RNAs (circRNAs), a unique class of non-coding RNAs, have emerged as key epigenetic regulators. …”
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A Lightweight Network with Domain Adaptation for Motor Imagery Recognition by Xinmin Ding, Zenghui Zhang, Kun Wang, Xiaolin Xiao, Minpeng Xu

“…Furthermore, domain adversarial training is employed to promote the learning of domain-invariant features, significantly enhancing the model’s cross-subject generalization ability. The proposed method was evaluated on an fNIRS motor imagery dataset, achieving an average accuracy of 87.76% in a three-class classification task. …”
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Janus kinase inhibitors in rheumatoid arthritis-associated interstitial lung disease: where do we stand and what may be the future? by Beatrice Maranini, Roberta Foti, Moustapha Taha, Veronica Venturelli, Andrea Lo Monaco, Marcello Govoni

“…The objective of this narrative review is to summarize the current evidence of the efficacy and safety of JAKis in RA-ILD management, investigating a possible emerging role for this drug class in such subset of patients. Results. Current studies focusing on JAKis in RA-ILD are scarce, but they globally report an overall stabilization of respiratory symptoms, functional data, and radiographic extension of ILD. …”
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Os jovens e o reconhecimento da empatia: análise descritiva da reatividade interpessoal em jovens de diferentes contextos sociais by Nilton S. Formiga

“…Estas poderiam diferenciar nos jovens em função do sexo, idade e classe social. O presente estudo tem como objetivo avaliar relação inter-dimensão nos fatores da empatia e a diferença na média de resposta dos jovens de diferentes contextos sócio-institucionais. 46 sujeitos, do sexo masculino e do sexo feminino, de 12 a 21 anos, de instituição social para cuidados de jovens em situação de riso, instituição religiosa cristã e de colégio público na cidade de João Pessoa-PB responderam a escala multidimensional de reatividade interpessoal de Davis. …”
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Development and Validation of a Three-Dimensional Diffusion Code Based on a High Order Nodal Expansion Method for Hexagonal-z Geometry by Daogang Lu, Chao Guo

“…The partially integrated radial and axial leakages are both approximated by the quadratic polynomial. The coarse-mesh rebalance method with the asymptotic source extrapolation is applied to accelerate the calculation. …”
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Adaptive grid‐driven probability hypothesis density filter for multi‐target tracking by Jinlong Yang, Jiuliu Tao, Yuan Zhang

“…Abstract The probability hypothesis density (PHD) filter and its cardinalised version PHD (CPHD) have been demonstratedasa class of promising algorithms for multi‐target tracking (MTT) with unknown,time‐varying number of targets. …”
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Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations by Ekaterina Bezpalaya, Svetlana Kurilova, Nataliya Vorobyeva, Elena Rodina

“…The current work describes the conformational dynamics of a structural model of human mitochondrial pyrophosphatase hPPA2 using molecular dynamics simulation, all-atom principal component analysis, and coarse-grained normal mode analysis. In addition to the wild-type enzyme, four mutant variants of hPPA2 were characterized that correspond to the natural pathogenic variants causing severe mitochondrial dysfunction and cardio pathologies. …”
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Word wall media in teaching vocabulary to junior secondary school students: teacher’s practices, benefits, and challenges by Syamsul Huda, Windhariyati Dyah Kusumawanti

“…The application of word wall also benefited the EFL teacher in designing vocabulary teaching and learning that suited the students’ language target and managed the class in a more engaged way. Further, the teacher encountered some challenges in applying the word wall media, including student teamwork, application consistency, and the learning media’s practicality.…”
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Evaluation of land use change, modeling and prediction of areas susceptible to physical development of the city (Case Study: Nurabad Mamasani Town) by rahman zandi, najmeh shafiei, ebrahim akbari, ali hajizadeh shikhanlo

“…Finally, the final map with the two models was classified into five classes. The results of the research showed that up to 1404 horizons of the city were developed eastwards in Although this pathway is not a suitable route, due to the existence of the main Kazeroun fault and the main waterway, the most important risk factors in the city are considered to be the best place for the development of the city of the western and southwestern regions of the region, which is 13% of the area of ​​the basin Includes.…”
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Unzipping of knotted DNA via nanopore translocation by Antonio Suma, Cristian Micheletti

“…Here we use molecular dynamics simulations and a coarse-grained model of DNA to address the nanopore unzipping of DNA filaments that are knotted. …”
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Person Re-Identification Using Additive Distance Constraint With Similar Labels Loss by Guofa Li, Lisha Huang, Liangwen Tang, Chunli Han, Yaoyu Chen, Heng Xie, Shen Li, Gang Xu

“…Despite the promising progress made in recent years, person re-identification (Re-ID) remains a challenging task due to the intra-class variations. Most of the current studies used the traditional Softmax loss for solutions, but its discriminative capability encounters a bottleneck. …”
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Dual-Granularity Feature Alignment for Change Detection in Remote Sensing Images by Feng Zhou, Xinyu Zhang, Hui Shuai, Renlong Hang, Shanshan Zhu, Tianyu Geng

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Correlation between risk factors that influence the development of children's language by Marianna Momoe Nanakuma Matsumoto, Heloisa Adhmann Ferreira, Isabelly Bueno Araujo, Daniela Cardilli-Dias, Daniela Regina Molini-Avejonas

“…Results Of the 194 participants, 62.4% had altered PDLs, and the risk factors that were most common in this group were male gender; being white; having a family socioeconomic level of upper middle, lower middle or low class; having a level of education up to high school; having a child with an altered temperament and having a mother with an altered temperament. …”
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Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences by Gloria Ortiz-Guerrero, Diana Amador-Muñoz, Carlos Alberto Calderón-Ospina, Daniel López-Fuentes, Mauricio Orlando Nava Mesa

“…PPIs are a widely indicated class of drugs for gastric acid-related disorders, although most older adult users are not treated for the correct indication. …”
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Do higher educated people feel happier?-Evidence of Han and minority nationalities from China. by Yuanyuan Wang, Zhenyi Hu, Jiameng Yuan, Kun Zhang

“…Based on the data of China General Social Survey (CGSS), this study adopts empirical analysis method to explore the impact of education on residents' subjective well-being and its differentiated mechanism in different ethnic groups. …”
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