Mirizzi Syndrome: Diagnosis and Management of a Challenging Biliary Disease by Gennaro Clemente, Andrea Tringali, Agostino M. De Rose, Elena Panettieri, Marino Murazio, Gennaro Nuzzo, Felice Giuliante

“…Two cases (11.1%) of gallbladder cancer associated with the Mirizzi syndrome were incidentally found: a patient underwent right hepatectomy and another patient was unresectable. The overall morbidity rate was 16.6%. …”
Get full text

Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage by Anastasiia Razdaibiedina, Mykhaylo Khobzey, Victoria Tkachenko, Iryna Vorobiova

“…However, genetic variation from one individual to another results in variation in levels of Th1/Th2 cytokines, strength of identification of infectious agents by Toll-like receptors, and quality of progesterone recognition. …”
Get full text

Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…We previously generated a DiCre-expressing P. berghei line and validated it by conditionally deleting several essential asexual stage genes, revealing their important role also in sporozoites. Another potent tool is the CRISPR/Cas9 technology, which has enabled targeted genome editing with higher accuracy and specificity and greatly advanced genome engineering in Plasmodium spp. …”
Get full text

The Application of Integrated Assisted History Matching and Embedded Discrete Fracture Model Workflow for Well Spacing Optimization in Shale Gas Reservoirs with Complex Natural Fra... by Qiwei Li, Jianfa Wu, Cheng Chang, Hongzhi Yang, Chuxi Liu, Wei Yu, Kamy Sepehrnoori, Jijun Miao

“…The biggest challenge for well spacing optimization is interpreting the subsurface uncertainties associated with hydraulic and natural fractures. Another challenge is the existence of complex natural fractures. …”
Get full text

Environmental assessment of river water quality near oil and gas fields by A.S. Patimah, A. Prasetya, S.H.M.B. Santosa

“…Samples at three locations were further tested with 13 additional chemical parameters due to potential contamination by other substances as they were located the closest to the production site and office area.FINDINGS: Sample analysis with six parameters showed a pollution index value of 0.558 or within the predefined standard at one location (SW6) and 1.080–2.721 at the other six locations, indicating slight pollution. Another test at three selected locations (i.e., SW1, SW2, and SW7) with 13 additional parameters increased the pollution index to 5.556–6.170 (moderate pollution). …”
Get full text

Cultural Dyphemisms in the Turkish Culture Region by İlhami Durmuş

“…Going from the plateau to winter quarters and from pasture to another pasture was made easy thanks to these. The finding which took out from graves reflects to all features of the culture.The ruins of nomad houses and horses were arised from the graves . …”
Get full text

The influence of the use of regulatory codes on the diagnosis of pathologies of reinforced concrete frame bridges by Lakhal Sebahi, Mohamed Bensoula, Mohamed Zaoui, Tahar Kadri

“…A diagnosis of the condition of the bridge was carried out on the basis of a preliminary visual inspection by making a schematic and photographic finding of the main issues and another inspection based on experimentation by carrying out several tests in situ and in the laboratory, which led to its classification in 2E according to the manual image of the quality of works of art (IQOA). …”
Get full text

Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonists for the treatment of obesity and diabetes mellitus by Alexander C. Martins, Beatriz G. de la Torre, Fernando Albericio

“…In this context, tirzepatide stands out as a medication targeting key hormones involved in obesity and DM. Another potential breakthrough, retatrutide, is also being developed for these two conditions, but it requires further research. …”
Get full text

RUSSIAN-ARAB COOPERATION BEFORE AND AFTER THE "ARAB SPRING" by M. A. Sapronova

“…Analyzes the problems faced by Russia in the development of foreign policy doctrine in the region of the Arab East, becoming the successor of the Soviet Union; difficulty in building bilateral relations with Iraq, Syria, Libya, and Russia's role as a co-sponsor of the Middle East settlement. Next is considered the foreign policy in 2000 and the return of Russia to the «Greater Middle East», analyzes the problems impeding effective Russian- Arab cooperation. …”
Get full text

DNA Ligase IV Prevents Replication Fork Stalling and Promotes Cellular Proliferation in Triple Negative Breast Cancer by Rashmi R. Joshi, Sk Imran Ali, Amanda K. Ashley

“…We previously established that DNA-PKcs, a NHEJ protein, promotes genomic stability and cell viability following cellular exposure to replication stress; we wanted to discern whether another NHEJ protein, DNA ligase IV (Lig4), shares this phenotype. …”
Get full text

Potential use of the Maroua (Far North, Cameroon) river sand as construction materials and degreasing agent for earthenware ceramics by Mahamad Nafissatou, Bertin Pagna Kagonbé, Arnaud Ghislain Anombogo Mouthe, Bouba Nafissa, Viviane Djaoyang Bakaïné, Etienne Yanné, Likiby Boubakar, Armand Kagou Dongmo

“…The results indicate that the grain size distribution varies slightly from one site to another. Organic matter content is relatively poor; it ranges from 0.26 to 0.67%. …”
Get full text

In search of prosociality in rodents: A scoping review. by Valérie Charron, Joey Talbot, Patrick R Labelle, Anne T M Konkle, Hélène Plamondon

“…Prosocial behavior is characterized by an action done to benefit another or promote their well-being. The goal of this scoping review is to characterize current findings regarding prosocial paradigms in rodents, highlight current gaps in reporting, and identify factors shown to be important in mediating prosocial responses in rodents. …”
Get full text

Gender-Based Motivational Factors For Choosing Dentistry As A Career By First Year Dental Students Of College Of Pakistan by Faiza Siddiqa, Seemi Tanvir, Ayesha Fazal, Ayesha Naveed, Sadia Sajjad, Sadia Manzoor

“…Students who choose dentistry by their own choice excel better in this field. Another general impression is that mostly female students prefer it. …”
Get full text

Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A Systematic Review and Meta-Analysis by Tasneem Rashed, Nura Alkhalefa, Alaa Adam, Abdulaziz AlKheraif

“…However, the clinical efficacy of these interventions when compared to one another is uncertain. The aim of the present systematic review with meta-analysis was to compare pit and fissure sealants with fluoride varnish for caries prevention of first permanent molars among schoolchildren. …”
Get full text

ECG heartbeat classification using progressive moving average transform by Rabah Mokhtari, Samir Brahim Belhouari, Khelil Kassoul, Abderraouf Hocini

“…Our approach integrates PMAT with a 2D-Convolutional Neural Network (CNN) model for the classification of ECG heartbeat signals. …”
Get full text

Feature engineering on climate data with machine learning to understand time-lagging effects in pasture yield predictionGitHub by Thirunavukarasu Balasubramaniam, Wathsala Anupama Mohotti, Kenneth Sabir, Richi Nayak

“…However, different pasture species respond to climate attributes with varying time lags; for example, one species might be more influenced by last week’s weather while another by the previous month’s highlighting the nuanced temporal dependencies. …”
Get full text

The geographical digital divide in broadband access and governmental policies in Japan: three case studies by Yoshio Arai, Sae Naganuma

“…The challenge of digitizing terrestrial television broadcasting has been behind these policies. Another effective means of extending broadband has been the pressure exerted by local governments (under the national policy scheme) on private cable television companies to bring their services to even the least populated regions. …”
Get full text

Curcumin Protects Human Umbilical Vein Endothelial Cells against H2O2-Induced Cell Injury by Jipeng Ouyang, Rong Li, Haiqin Shi, Jianping Zhong

“…In the present study, human umbilical vein endothelial cells (HUVECs) were pretreated with various concentrations of curcumin (0 μM, 10 μM, 20 μM, 30 μM, 40 μM, and 50 μM) for 12 h, thereby exposed to H2O2 (100 μM) for another 12 h. The viability of HUVECs was tested by the CCK-8 assay, and the activities of antioxidant enzymes including superoxide dismutase (SOD) and glutathione (GSH) were also examined. …”
Get full text

TNF Superfamily: A Growing Saga of Kidney Injury Modulators by Maria D. Sanchez-Niño, Alberto Benito-Martin, Sara Gonçalves, Ana B. Sanz, Alvaro C. Ucero, Maria C. Izquierdo, Adrian M. Ramos, Sergio Berzal, Rafael Selgas, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz

“…While TNF only activates canonical NF-kappaB signaling, TWEAK promotes both canonical and noncanonical NF-kappaB activation in tubular cells, regulating different inflammatory responses. …”
Get full text

Voice pathology detection using machine learning algorithms based on different voice databases by Nurul Mu'azzah Abdul Latiff, Fahad Taha Al-Dhief, Nurul Fariesya Suhaila Md Sazihan, Marina Mat Baki, Nik Noordini Nik Abd. Malik, Musatafa Abbas Abbood Albadr, Ali Hashim Abbas

“…The application of machine learning in analyzing voice disorders has become crucial for non-invasive voice pathology detection using voice signals. …”
Get full text