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Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and...
Published 2025-02-01“…Abstract Low immune infiltration is closely associated with poor clinical results and an unfavorable response to therapy in triple-negative breast cancer (TNBC). T-cell exhaustion (TEX) is a significant risk factor for tumor immunosuppression and invasion. …”
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Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells
Published 2025-03-01“…Triple-negative breast cancer (TNBC) is the most lethal breast cancer subtype, leading to poor patient outcomes despite aggressive treatment with surgery, radiation, and chemotherapy. …”
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364
Geological characteristics of deep coal rock and main geological factors controlling coalbed methane enrichment: a case study of the M area in the eastern Ordos Basin
Published 2025-01-01“…These severely restrict the efficient exploration of deep CBM. To promote increased reserves and efficient production of deep CBM, and to further develop the enrichment theory of deep CBM in the eastern Ordos Basin, a comprehensive study was conducted based on core observations, experimental tests, scanning electron microscopy, well logging data from 76 wells in the study area, and 3D seismic data. …”
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365
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Published 2021-05-01“…DNGR-1 (CLEC9A) is a dead cell-sensing receptor highly restricted to cDC1s. …”
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366
The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer
Published 2025-02-01“…Inflammation-related indicators has been recognized as outcome predictors in triple-negative breast cancer (TNBC). Our study aimed to investigate the predictive value of several inflammation-related indicators in TNBC patients underwent chemotherapy (NAC). …”
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367
Comparación del tiempo de cicatrización entre N-butil cianoacrilato y ácido poliglicólico en caninos sometidos a esterilización
Published 2019-01-01“…El objetivo de este estudio fue comparar el tiempo de cicatrización entre N-butil cianocrilato (NBC) y ácido poliglicólico (AC) sobre el cierre tisular en caninos sometidos a operaciones de esterilización. …”
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368
Prognostic factors in hereditary breast cancer: A review
Published 2024-08-01“…BRCA1-associated breast cancer is often triple-negative (TNBC), which has a more aggressive course and poorer prognosis. …”
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369
Conservación basada en comunidad: importancia y perspectivas para Latinoamérica
Published 2016-01-01“…En los resultados del trabajo se reporta en qué consiste la CBC, su relevancia en Latinoamérica y sus temas torales: el socio-ecosistema, la multiescala, los tomadores de decisiones, la apropiación de las estrategias de conservación, las estrategias multi-objetivo, así como las perspectivas de la CBC para América Latina. …”
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370
UBE2T/CDC42/CD276 signaling axis mediates brain metastasis of triple-negative breast cancer via lysosomal autophagy
Published 2025-02-01“…Finally, animal experimental results also showed that inhibition of UBE2T elevated the TNBC sensitivity to immune checkpoint CD276 blockade and inhibited BrM of TNBC.Conclusions In conclusion, our results indicate a new mechanism whereby UBE2T-mediated ubiquitination positively controls the UBE2T/CDC42/CD276 axis to upregulate tumor cell expression of CD276 and thereby impair CD8+ T cells function, ultimately leading to tumor cell immune escape and BrM.…”
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371
Machine Learning with Tunicate Swarm Optimization for Improved Disc Herniation Prediction
Published 2024-06-01“…This study employs Extra Tree Classification (ETC), Naïve Bayes Classification (NBC), and Logistic Regression Classification (LRC) to forecast disk herniation. …”
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Comparison of Selected Aspects of English Subject in the New and the Old Secondary Curriculum.
Published 2024“…The findings further revealed that the teachers were not conversant with the aims and objectives in the CBC curriculum yet they are expected to implement the same. …”
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374
Design of Arduino Computer Numerical Control Machine.
Published 2023“…Hence there is a need for the design of an affordable CNC machine for manufacturers and students/ innovators. …”
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As mobilidades da sátira na metaficção historiográfica: uma leitura de Galvez, imperador do Acre
Published 2005-01-01Get full text
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377
Filhos de Macunaima ou: não sou índio, sou macuxi e meu nome é...
Published 2018-01-01Get full text
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378
The INFLUENCE 3.0 model: Updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy
Published 2025-02-01“…Cox regression with restricted cubic splines was compared to Random Survival Forest (RSF) to predict five-year LRR and CBC risks. …”
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