Atezolizumab plus bevacizumab in patients with unresectable or metastatic mucosal melanoma: 3‐year survival update and multi‐omics analysis by Jie Dai, Tianxiao Xu, Lifeng Li, Meiyu Fang, Jing Lin, Jun Cao, Xue Bai, Caili Li, Xiaoting Wei, Junjie Gu, Yaoyao Liu, Xuan Gao, Xuefeng Xia, Jun Guo, Yu Chen, Lili Mao, Lu Si

“…Results With a median follow‐up of 40.3 months, the median overall survival (mOS) was 23.7 months (95% confidence interval [CI], 15.1–34), and the 3‐year OS rate was 28.7% (95% CI, 17.6%–46.8%). …”
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CONSERVATION STATUS AND RESEARCH ON PROPAGATION OF CAMELLIA PIQUETIANA IN LAM DONG PROVINCE, VIETNAM by Hong En Le, Quang Cuong Truong, Van Cam Ngo, Pham Doan Nguyen, Van Phuc Nguyen, Van Duong Do, Thi Thuy Hoa Le, Si Hung Ho, Ba Trung Nguyen, Giang Phi Ngo, Thi Phuong Ho

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A qualitative study of stigma in patients with low anterior resection syndrome of rectal cancer (直肠癌低位前切除综合征患者病耻感的质性研究) by WEN Ruizhen (温瑞珍), CHEN Piao (陈飘), LI Yalan (李亚兰), CAO Aifang (曹爱芳), WANG Miaolan (王淼兰), ZHENG XiaoXuan (郑筱暄), PENG Hui (彭慧)

“…Results The stigma of patients with LARS can be summarized into three themes. Theme 1: Stigma experiences, including feelings of shame, discrimination, and loneliness; Theme 2: Determinants of stigma, including disease factors and lack of public knowledge; Theme 3: Stigma sensing approaches, including avoiding social contact, concealing the condition, and actively coping. …”
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COVID-19 in discharged patients with diabetes and chronic kidney disease: one-year follow-up and evaluation by Enrong Ran, Enrong Ran, Yutong Zou, Chuanyi Zhao, Kai Liu, Jiamin Yuan, Wenjie Yang, Lijun Zhao, Qing Yang, Jia Yang, Xuegui Ju, Linli Cai, Yanlin Lang, Xingyuan Li, Ke Liu, Fang Liu, Fang Liu

“…Cox regression analysis was used to assess mortality risk, and logistic regression was applied to identify risk factors for rapid CKD progression after discharge.ResultsDuring the one-year follow-up, the all-cause mortality rate was 26.7%, with a COVID-19-related acute kidney injury (AKI) incidence of 35.3%, and 35.8% of patients experienced rapid CKD progression after discharge. …”
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Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy by Lianhui Sun, Guangjian Fan, Zhuqing Zhang, Dong Chang, Xiaoyu Zhang, Tongqing Zhang, Jichuan Geng, Xiaoxia Zhang, Menghan Lin, Chen Hu, Jiaqi Zhou, Mengxue Wang, Liu Cao, Mary Zhang, Baokun He, Shengping Zhang, Chuangui Wang

Subjects: “…CP: Molecular biology…”
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Integration of ordered porous materials for targeted three-component gas separation by Xue Jiang, Yu Wang, Hui Wang, Lu Cheng, Jian-Wei Cao, Jin-Bo Wang, Rong Yang, Dong-Hui Zhang, Run-Ye Zhang, Xiu-Bo Yang, Su-Hang Wang, Qiu-Yu Zhang, Kai-Jie Chen

“…As a proof of concept, two ultramicroporous nanocrystals (one for C2H2-selective and the other for CO2-selective) as the shell pores were respectively grown on a C2H6-selective ordered porous material as the core pore. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

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Association between airway microbiota and systemic inflammation markers in non-small cell lung cancer patients by DanHui Huang, QianNan Ren, LingYan Xie, YueHua Chen, Cui Li, XiaoFang Su, LiShan Lin, LaiYu Liu, Haijin Zhao, Tingyue Luo, JianHua Wu, Shaoxi Cai, Hangming Dong

“…Neutrophil-lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR) and C reactive protein (CRP) were used to represent systemic inflammation. …”
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The impact of long-term exposure to NO2, O3, and their oxidative potential on adolescents’ mental health, and the protective role of school-based greenness by Jiajia Dang, Yaqi Wang, Ning Ma, Shan Cai, Jianhui Guo, Yunfei Liu, Haoyu Zhou, Xinyao Lian, Di Shi, Ziyue Chen, Yihang Zhang, Jiaxin Li, Tianyu Huang, Guangrong Zhu, Jing Li, Jun Ma, Yi Song

“…Each IQR (Interquartile Range) increase in OX was related to adverse mental health outcomes, with ORs of 1.17 (95 % CI: 1.06, 1.29) for being vulnerable, 1.20 (95 % CI: 1.12, 1.28) for being more symptomatic but content, and 1.15 (95 % CI: 1.07, 1.23) for being troubled. …”
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Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer by Xiaofeng Wang, Chen Li, Jie Chen, Zhiqiang Wu, Zhen Zhang, Junyi Li, Lu Yu, Yong Guan, Yuhan Zhang, Yuanjie Cao, Yancheng Liu, Hui Bai, Shaochuan Liu, Miaomiao Gao, Chenglu Lu, Zhen Tao, Zhiyong Yuan

“…Background As an unconventional subpopulation of T lymphocytes, γδ T cells can recognize antigens independently of major histocompatibility complex restrictions. …”
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Ugochukwu, Oliver Ukachi by Maduabuchi , Patrick Aja, Chukwu, Chinecherem Adanna, Okechukwu, Ugwu Paul Chima, Anthony, Boniface Ale, Chinedu , Peter Agu, Deusdedi, Tusubira, Chukwu, Darlington C, Onyedika, Gabriel Ani, Ugbala, Ezebuilo Ekpono, Akobi , Hilary Ogwoni, Awoke , Joshua Nonso, Ogbu, Patience N, Aja, Lucy, Orji, Obasi Uche, Nweke, Chinoso Peter, Egwu, Chinedu, Ekpono, Ejike Ugbala, Ewa, Gift Onyinyechi, Igwenyi, Ikechuku Okorie, Esther, Alum Ugo, Uti, Daniel Ejim, Offor, Christian Emeka, Ifie, Josiah E., Njoku, Amaobichukwu, Kenneth, Ekenechukwu, Ejike, Daniel Eze

“…Groups: A (one milliliter of olive oil, regardless of weight), B (BPA 100 mg/kg body weight (BW)), C (CMSO 7.5 mg/kg BW), D (CMSO 7.5 mg/kg BW + BPA 100 mg/kg BW), E (CMSO 5.0 mg/kg BW + BPA 100 mg/kg BW), and F (CMSO 2.5 mg/kg BW + BPA 100 mg/kg BW). …”
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Bifurcation of time crystals in driven and dissipative Rydberg atomic gas by Bang Liu, Li-Hua Zhang, Yu Ma, Qi-Feng Wang, Tian-Yu Han, Jun Zhang, Zheng-Yuan Zhang, Shi-Yao Shao, Qing Li, Han-Chao Chen, Guang-Can Guo, Dong-Sheng Ding, Bao-Sen Shi

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Evolution of aroma compounds in round soy sauce aroma type baijiu during aging and the effect of aging markers on the lasting aroma in finished glass by Shi-Yi Wang, Chen Li, Yu-Jie Li, Guang-Qian Liu, Zhen-Ming Lu, Li-Juan Chai, Hong-Yu Xu, Jin-Song Shi, Song-Tao Wang, Cai-Hong Shen, Xiao-Juan Zhang, Zheng-Hong Xu

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Documentation of lead exposure-associated comorbidity among 4538 workers in China by Qian Hua, Pingyang Zhang, Yong Yang, Jingchao Ren, Shouming Cui, Yuxin Yang, Loulou Cai, Jia Ding, Shouyuan Cui, Mingyang Gao, David C. Christiani, William Au, Yanchun Ma, Zhongjun Du, Guang-hui Zhang, Zhao-lin Xia

“…Results Among the 4538 recruited workers, there were 2780 males and 1758 females, with a median age of 34 years old, and BLC ranging from 7.70 to 722.70 μg/l. Among them, 1247 (27.4%) had multiple morbidities (comorbidity). …”
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Atrial Arrhythmias in Patients with Severe COVID-19 by Kai-Yue Han, Qi Qiao, Ye-Qian Zhu, Xin-Guang Chen, Xing-Xing Kang, Gao-Feng Zhang, Xun-Chao Cai, Yong Du, Jing Jin, Ruo-Min Di, Chen-Xi Yang, Feng-Xiang Zhang, Ying-Jia Xu

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Lipoprotein Nanoplatform for Targeted Delivery of Diagnostic and Therapeutic Agents by Jerry D. Glickson, Sissel Lund-Katz, Rong Zhou, Hoon Choi, I-Wei Chen, Hui Li, Ian Corbin, Anatoliy V. Popov, Weiguo Cao, Liping Song, Chenze Qi, Diane Marotta, David S. Nelson, Juan Chen, Britton Chance, Gang Zheng

“…A semisynthetic nanoparticle has been constructed by coating magnetite iron oxide nanoparticles with carboxylated cholesterol and overlaying a monolayer of phospholipid to which apolipoprotein A1 or E was adsorbed for targeting HDL or adsorbing synthetic amphipathic helical peptides ltargeting LDL or folate receptors. These particles can be used for in situ loading of magnetite into cells for MRI-monitored cell tracking or gene expression.…”
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Overcoming hypoxia-induced breast cancer drug resistance: a novel strategy using hollow gold-platinum bimetallic nanoshells by Lian-Ying Zhang, Xiao-Tong Chen, Rong-Tian Li, Wei Meng, Guo-Qin Huang, Yong-Jian Chen, Feng-Jun Ge, Qun Zhang, Yu-Jun Quan, Cai-Tao Zhang, Yi-Fei Liu, Ming Chen, Jin-Xiang Chen

“…This process alleviates tumor hypoxia and down-regulating hypoxia-inducible factor-1α (HIF-1α), multidrug resistance gene 1 (MDR1), and P-glycoprotein (P-gp), which can reverse drug resistance and achieve more effective DOX chemotherapy effects. …”
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Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater by Bui Van Hoi, Cam-Tu Vu, Lan-Anh Phung-Thi, Thao Thi Nguyen, Phuong Thanh Nguyen, Huong Mai, Phuong-Thu Le, Thanh-Hien Nguyen, Dao Thanh Duong, Hue Nguyen Thi, Dung Le-Van, Dinh Binh Chu

“…In this study, an analytical method for the simultaneous determination of 7 major pharmaceutical residues in Vietnam, namely, carbamazepine, ciprofloxacin, ofloxacin, ketoprofen, paracetamol, sulfamethoxazole, and trimethoprim, in surface water and hospital wastewater has been developed. …”
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The Role of the Entorhinal Cortex in Extinction: Influences of Aging by Lia R. M. Bevilaqua, Janine I. Rossato, Juliana S. Bonini, Jociane C. Myskiw, Julia R. Clarke, Siomara Monteiro, Ramón H. Lima, Jorge H. Medina, Martín Cammarota, Iván Izquierdo

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Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis by Junbin Liao, Junbin Liao, Wenfeng Cai, Danrong Lin, Yuanyun Xiao, Yanxi Liu, Yahui Wang, Yuquan Zhong, Fan Xiao, Heng Fang, Yilu Yao, Yunfeng Lin, Jiewen Su, Siyu Sun, Bo Zhang, Yan Wang, Wei Zhu, Wei Zhu

“…Restricted cubic spline and sensitivity analyses were used to assess the association between DII and the degree of disability of the older adult population.ResultsInactivity (never exercising, OR = 8.48, 95% CI = 2.30–31.31) and reduced activity (formerly exercising, OR = 4.85, 95% CI = 1.39–16.96), stroke (OR = 2.78, 95% CI = 1.61–4.80), and dementia (OR = 2.69, 95% CI = 1.26–5.78) were significantly associated with increased disability. …”
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