Phytochemical investigation and assessment of the anti-inflammatory activity of four Heracleum taxa growing in Turkey by Ekin Kurtul, Esra Küpeli Akkol, Büşra Karpuz Ağören, Büşra Yaylacı, Özlem Bahadır Acıkara, Eduardo Sobarzo-Sánchez, Eduardo Sobarzo-Sánchez

“…Additionally, the coumarin contents of the extracts were quantified as mg/g by high-performance liquid chromatography.Results and discussionH. sphondylium subsp. cyclocarpum roots displayed the highest inhibition for carrageenan, prostaglandin E2, and serotonin-induced hind paw edema, with inhibition ranges of 22.8%–36.9%, 5.4%–35.7%, and 3.9%–17.9%, respectively, while the inhibition ranges for indomethacin were 12.8%–44.3%, 2.7%–41.3%, and 7.1%–30.6%, respectively. …”
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Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function by Tong Wang, Ying Shen, Tianjiao Zhang, Chuan He, Qian Lu, Jie Song, Manyu Dong, Yilun Qian, Sisi Huang, Jing Teng

“…Subgroup analysis further demonstrated a significant reduction in SAI level among individuals aged 70–80 years in comparison to both the younger adults (SAI(N20): (t=−3.37, p=0.018); SAI(N20+4): (t=−3.13, p=0.038)) and those aged 60–70 (SAI(N20): (t=−3.26, p=0.025); SAI(N20+4): (t=−3.69, p=0.006)). …”
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Hypnotics' association with mortality or cancer: a matched cohort study by Daniel F Kripke, Lawrence E Kline, Robert D Langer

“…For groups prescribed 0.4–18, 18–132 and >132 doses/year, HRs (95% CIs) were 3.60 (2.92 to 4.44), 4.43 (3.67 to 5.36) and 5.32 (4.50 to 6.30), respectively, demonstrating a dose–response association. …”
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Relationship between upper extremity fat mass and race time in triathlete by Ebru Cetın, Ulviye Bılgın, Mergul Colak, İmdat Yarım, Halil Taskın

“…This study was conducted to investigate the effect of upper extremity fat ratio on triathletes’ the race time. 43 volunteer athletes who participated in the 9th World University Triathlon Championship ((17 women – 26 men), age 22.30 ± 2.42 years, height 172.76 ± 16.08 cm, body weight 64.79 ± 9.93 kg)) participated in the study. …”
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Budget Impact of RefluxStop™ as a Treatment for Patients with Refractory Gastro-oesophageal Reflux Disease in the United Kingdom by Sam Harper, Lukasz Grodzicki, Stuart Mealing, Elizabeth Gemmill, Paul Goldsmith, Ahmed Ahmed

“…**Results:** Over 5 years, introducing RefluxStop™ allowed the avoidance of 347 surgical failures, 39 reoperations, and 239 endoscopic esophageal dilations. …”
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Hallazgos electrocardiográficos en deportistas mexicanos bajo los criterios internacionales de Seattle 2017 en el Centro de Medicina de la Actividad Física y del Deporte by Héctor Manuel Tlatoa Ramirez, Luis Donaldo Garcia Segura, María Lizzeth Márquez López, Gerardo Armengol Vargas, Salvador Lopez Rodriguez, María Fernanda Villegas Rodríguez, Hugo Mendieta Zeron, Jose de Jesus Garduno Garcia

“…Resultados: Se observó que el 53.9% de los deportistas presentan cambios electrocardiográficos, con hallazgos normales 35.7%, los hallazgos anormales y limítrofes están presentes con 4.4% y 13.8% en los ECG analizados. …”
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Efficacy of the cross-union protocol in the treatment of congenital tibial pseudarthrosis: a comparative study by Yanhui Jing, Dahui Wang, Chunxing Wu, Zhiqiang Zhang, Yueqiang Mo, Bo Ning

“…The time to union was significantly shorter in Group A (3.37 ± 0.64 months) compared to Group B (8.67 ± 3.0 months). …”
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Post-vaccination campaign evaluation of systemic and mucosal immunity of trivalent oral poliovirus vaccine in Karachi, Pakistan (2020–2021): a cross-sectional studyResearch in cont... by Ali Faisal Saleem, Visalakshi Jeyaseelan, Zaubina Kazi, Mahjabeen Zehra, Muhammad Masroor Alam, Grace Macklin, Rocio Lopez Cavestany, Sajid Muhammad, Najeeb Rehman, Ondrej Mach

“…The seroconversion rate for type 2 was 72% (44/61, 95% CI: 59.8–81.8) after the first tOPV dose; cumulative seroconversion after two doses was 93.4% (95% CI: 84.3–97.4). …”
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Analysis of parameters of purine metabolism in patients with diabetes mellitus type 2 by A.O. Chernyaeva, M.R. Mykytyuk, Yu.I. Karachentsev

“…The aim of this research is to comprehensively analyze the current state of purine metabolism as well as assess its features in patients with diabetes mellitus type 2, taking into account the clinical and metabolic polymorphism of the disease. The authors examined 327 patients with diabetes mellitus type 2 (144 men and 183 women), a group of individuals with an average age of 57.8±10.1 years. …”
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Factors Associated with Anemia among Children Aged 6–23 Months Attending Growth Monitoring at Tsitsika Health Center, Wag-Himra Zone, Northeast Ethiopia by Haile Woldie, Yigzaw Kebede, Amare Tariku

“…In multivariate logistic regression analysis, male sex (AOR = 3.1 (95% CI: 1.60–5.81)), 9–11 months of age (AOR = 9.6 (95% CI: 3.61–25.47)), poor dietary diversity (AOR = 3.2 (95% CI: 1.35–7.38)), stunting (AOR = 2.7 (95% CI: 1.20–6.05)), diarrhea (AOR = 4.9 (1.63–14.59)), no formal education (AOR = 2.6 (95% CI: 1.26–5.27)), early initiation of complementary food (AOR = 11.1 (95% CI: 4.08–30.31)), and lowest wealth quintile (AOR = 3.0 (95% CI: 1.01–8.88)) were significantly associated with anemia. …”
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The prevalence of latex sensitisation and allergy and associated risk factors among healthcare workers using hypoallergenic latex gloves at King Edward VIII Hospital, KwaZulu-Natal... by Shumani Makwarela Phaswana, Saloshni Naidoo

“…A dose–response relationship was observed for powdered latex gloves (OR 1.1; 95% CI 1.0 to 1.2). Atopy (OR 1.5; 95% CI 0.7 to 3.3 and OR 1.4; 95% CI 0.6 to 3.2) and fruit allergy (OR 2.3; 95% CI 0.8 to 6.7 and OR 3.1; 95% CI 1.1 to 9.2) also increased the risk of latex sensitisation and allergy.Conclusions This study adds to previous findings that healthcare workers exposed to hypoallergenic latex gloves are at risk for developing latex sensitisation highlighting its importance as an occupational hazard in healthcare. …”
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Comparative effective dose of ciprofol and propofol in suppressing cardiovascular responses to tracheal intubation by Min Liao, Xiao-Ru Wu, Jia-Ning Hu, Xing-Zhou Lin, Tang‑yuan‑meng Zhao, Hu Sun

“…A total of 54 participants were included, with 24 in group C (1 excluded) and 30 in group P. Probit analysis revealed that the ED50 of ciprofol for inhibiting cardiovascular responses to tracheal intubation were 0.326 mg/kg (95% CI 0.304–0.337 mg/kg), and for propofol, 1.541 mg/kg (95% CI 1.481–1.599 mg/kg). …”
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The Relationship between the Activity Balance Confidence and Mobility Tests among Older Adults in Indonesia by Indri Hapsari Susilowati, Sabarinah Sabarinah, Susiana Nugraha, Sudibyo Alimoeso, Bonardo Prayogo Hasiholan, Supa Pengpid, Karl Peltzer

“…The older adult participants who are not confident will have 12.03 times higher the unstable result of the gait test, 8.4 times higher the unstable result of the balance test, and 7.47 times higher the less strength result of the strength test who are confident. …”
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A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China by Yanqiu Xiong, Shanshan Liang, Wenjiao Tang, Li Zhang, Yuhuan Zheng, Ling Pan, Ting Niu

“…Methods In a comprehensive analysis of 367 consecutive patients with symptomatic MM, we assessed the prognostic significance of +1q21 using FISH with a threshold of 7.4%. …”
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Effectiveness of carbon dioxide cryotherapy for the treatment of cutaneous leishmaniasis: Systematic review and meta-analysis. by Feleke Tilahun Zewdu, Bisrat Misganaw Geremew, Endalamaw Gadisa Belachew, Kassahun Alemu Gelay

“…<h4>Result</h4>Out of the 16 researches included in the review, seven papers with a total of 1,357 cases were chosen for the meta-analysis. For the treatment of cutaneous leishmaniasis, the pooled cure rate with carbon dioxide-based cryotherapy was 87.84% (95% CI: 65.92-109.77). …”
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胎盘位置影响胎盘早剥的妊娠结局分析

“…而后壁胎盘组的产后出血量显著多于前壁胎盘组［（８１８．７ ± ４９８．６） ｍＬ ｖｓ （４００．０ ± １３２．５）ｍＬ，Ｐ ＝ ０．００１］，后壁胎盘组需要输血的发生率也高于前壁胎盘组（３８．７％ｖｓ １０．０％，Ｐ ＝ ０．０２５）。…”
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Community-Based Health Insurance Utilization and Its Associated Factors among Rural Households in Akaki District, Oromia, Ethiopia, 2021 by Amenti Teka Geferso, Sisay Begashaw Sharo

“…The magnitude of community-based health insurance (CBHI) utilization was 398 (66.3%) (95% CI: 0.63, 0.70). In the multivariate logistic regression analysis, the odds of CBHI utilization for males were 2 times higher (AOR = 1.629; 95% CI: 1.063, 2.497) compared to female-headed households; household family size <5 was 3 times higher (AOR = 2.99; 95% CI: 1.987, 4.139) compared to household family size >5; farmer was 4 times higher (AOR = 3.763; 95% CI: 1.371, 10.327) compared to other occupational status; household income <30,000 ETB was 2 times higher (AOR = 2.474; 95% CI: 1.514, 4.043) compared to the household income of 30000 ETB, and all these were factors significantly associated with CBHI utilization. …”
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Chlamydia cases in women of reproductive age, 2006–2020: an analysis of surveillance data from Southern China by Peizhen Zhao, Peng Liang, Jinshen Wang, Wenqian Xu, Shujie Huang, Cheng Wang

“…The mean reported rate was 122.6 per 100,000 population over 15 years, significantly increasing from 1.4 in 2006 to 179.7 in 2020 (average annual percent change [AAPC] = 47.4%, 95% CI: 42.8%-52.2%, P < 0.05). …”
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Prediction and Evaluation of Water Resource Ecological Footprint in Beijing under the Influence of Changing Environment by QIN Huanhuan, HUANG Lixiang, WANG Jianquan

“…Ten sub-categories of scenarios are designed based on the system dynamics model for water resource utilization in Beijing to predict and evaluate the water resource ecological footprint in Beijing from 2022 to 2030 under the influence of changing environment.The results show that:① From 2022 to 2030,the water resource ecological footprint per capita under each scenario shows a downward trend (except for the scenario CC-wet),with an average value of 0.414~0.475 hm² per capita.The water resource ecological carrying capacity per capita shows a downward trend,with an average value of 0.101~0.139 hm² per capita.The average value of water resource ecological deficit per capita is 0.293~0.367 hm² per capita.The water resource ecological pressure index shows a fluctuating trend,with an average value of 3.225~4.608,and Beijing will face the situation of water resource unsafe utilization.The water resource ecological footprint intensity shows a significant downward trend,with an average of 0.013~0.024 hm²/10⁴ RMB,and the water resource utilization efficiency in Beijing is constantly improving.② As the climate is wetter,the ecological footprint,ecological deficit,ecological pressure,and ecological footprint intensity of water resources are smaller in Beijing and vice versa.③ Rapid economic development has a significant influence on the ecological footprint,ecological carrying capacity,ecological deficit,and ecological pressure index of water resources.The South-to-North Water Diversion Project (SNWDP) has an immediate effect on reducing the ecological footprint and ecological deficit of water resources.Water saving in animal husbandry has a small influence on the indicators related to the water resource ecological footprint.④ In its future development,Beijing should consider both economic development and water resource protection,take measures to deal with the possible influence of climate change,make full use of the SNWDP in promoting the sustainable use of water resources,and constantly improve the awareness of water conservation and the efficiency of production and domestic water use in the whole society,promoting the sustainable development and utilization of social economy and water resources in the capital through multi-pronged efforts.…”
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A Study of Some Biochemical Parameters in COVID-19 Patients with Diabetes Mellitus: Comparative Study by Asmaa Sattar Abd, Izzat Al-Rayahi

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