Phylogenetic analysis and detection of positive selection in the SIRT gene family across vertebrates by Qiuxi Zhou, Xiongtao Yang, Da Li, Jing Li, Ling Peng, Wenwu He

“…Eleven positively selected sites (23I, 310 S, 311I, 313 A, 316 K, 320 C, 321 A, 322Q, 323 H, 327E, 328P) were identified with high confidence (posterior probability ≥ 99%), suggesting critical roles in functional divergence. …”
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Validated UPLC-MS/MS Method for Determination of Futibatinib and Its Pharmacokinetics in Beagle Dogs by Heng Li, Hao-Zhe Ding, Yi-Lin Wang, Feng Zhang, Ya-Hao Song, Xiang-Jun Qiu

“…Futibatinib and IS were separated in an UPLC BEH C18 column (2.1 mm × 50 mm, 1.7 μm) with acetonitrile and 0.1% formic acid as the mobile phase, and the flow rate was 0.3 mL/min. …”
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A modeling study to define guidelines for antigen screening in schools and workplaces to mitigate COVID-19 outbreaks by Yong Dam Jeong, Keisuke Ejima, Kwang Su Kim, Shoya Iwanami, William S. Hart, Robin N. Thompson, Il Hyo Jung, Shingo Iwami, Marco Ajelli, Kazuyuki Aihara

“…For example, 44.5% (95% CI: 40.8–47.5) of infected individuals are identified by daily testing, whereas it is only 33.7% (95% CI: 30.5–37.3) when testing is performed at the end of the program duration. …”
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Economic burden of musculoskeletal disorders in Tanzania: results from a community-based survey by Stefan Siebert, Emma McIntosh, Manuela Deidda, Richard Walker, Ping-Hsuan Hsieh, Blandina Mmbaga, Clive Kelly, Kajiru Kilonzo, Eleanor Grieve, Elizabeth F Msoka, Kiula Kiula, Nateiya Yongolo, Sanjura Mandela Biswaro, Stefanie Krauth, Jo Halliday

“…Productivity costs of individuals with MSK disorders were Int$487 vs Int$132 in the control group (difference: Int$355, 95% CI Int$222 to Int$488). …”
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Incremental cost of treating antimicrobial-resistant infections among hospitalised patients in India: a cohort study by Sanjay M Mehendale, Kamini Walia, Pallab Ray, Nusrat Shafiq, Shankar Prinja, Sagar Khadanga, Susmita Chatterjee, Raman Gangakhedkar, Samiran Panda, Sanjay Bhattacharya, Megha Mamulwar, Abhijit Kadam, Gayatri Bhambure, Shilpa Bembalkar, Shraddha Bapat, Arati Mane, Shobha Rajure, Jayanthi Mathaiyan, Yamunadevi Ramanathan, Vijayshri Suresh Deotale, Gourangie Gogoi, Ruchita Attal, Jharna Mandal, Venkateswaran Ramanathan

“…Our study has revealed that the ICs for Enterobacteriaceae (53.9%), Acinetobacter (43.8%) and Staphylococcus (49.7%) at GHs were higher for resistant pathogens. …”
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Explaining the interactions of city and border with the sustainable development approach Based on the logic of fuzzy multi-criteria decision making Case study: Zahedan ,Mijaveh, D... by reza mohammadi, zyinab karkaabadi, ghlam reza miri

“…Using Cochran formula, 367 people were selected as the sample. Data were analyzed using Structured Analytical Model (SOWT-ANP). …”
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Sosyal Bilgiler Öğretmenliği Lisans Programı Akademik Yapısının İncelenmesi by Orhan Ünal, Nurbanu Şeren

“…Araştırmanın veri kaynağını Sosyal Bilgiler Öğretmenliği Lisans Programına öğrenci kabul eden 64 üniversitede görevli 377 öğretim üyesi oluşturmaktadır. Verilerin elde edilmesinde YÖK Lisans Program Atlası ve YÖK Akademik veri tabanları kullanılmıştır. …”
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Analysis of Waves in the Oman Sea Using Numerical Software and Field Data by Homayun Kalantari, Kamran Lari, Afshin Mohseni Arasteh, Masoud Torabi Azad

“…Simulated wave parameters after calibration and adjustment of white capping coefficients as a wave loss parameter corresponded with the results of the measurement data at three stations with a strong correlation of 90%, 86% and 80% and an improvement value of 7.6%, 4 6.6%, and 27.18%, respectively. …”
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腹腔镜超声结合内镜超声评估胰腺癌可切除性的临床价值

“…【目的】 探讨腹腔镜超声(LUS)结合术前内镜超声(EUS)评估胰腺癌可切除性的临床价值【方法】 对2006年3月至2009年10月临床诊断为胰腺癌的56例患者先后行EUS及LUS检查,对EUSLUS均判断肿瘤可以切除的患者行剖腹探查手术,最后证实确实可行根治性切除手术的患者,明确术前联合应用EUSLUS评估胰腺癌可切除性的临床价值【结果】 56例患者中仅35.7%可行根治性切除手术,91.7%的不能接受切除手术的患者因EUSLUS避免了剖腹探查;LUS判断肿瘤可切除的诊断特异性正确性及阳性预测值分别达76.9%90.3%及85.7%,明显高于单用EUS的63.9%76.8%及60.6%,而EUSLUS联合检查可进一步将诊断特异性和正确性提高到91.7%和94.4%【结论】 术前联合应用EUSLUS可以显著提高胰腺癌可切除性评估的准确性,使单纯开腹探查手术减少到10%以下,具有重要的临床价值…”
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A novel CUL4B gene variant activating Wnt4/β-catenin signal pathway to karyotype 46, XY female with disorders of sex development by Chunlin Wang, Hong Chen, Qingqing Chen, Yangbin Qu, Ke Yuan, Li Liang, Qingfeng Yan

Subjects: “…CUL4B…”
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Adult hypophosphatasia presenting with recurrent acute joint pain by Hayao Yoshida, Takaaki Murakami, Atsubumi Ogawa, Takashi Sunouchi, Naoko Hidaka, Nobuaki Ito, Hiromi Murakami, Hidenori Kawasaki, Tomoyuki Akiyama, Katsumi Nakajima, Daisuke Yabe, Taizo Yamamoto

“…While the patient had no history of premature loss of primary teeth, fragility fractures, muscle weakness or abnormalities in growth, genetic testing revealed a likely pathogenic and a pathogenic heterozygous variant in the ALPL gene, i.e., c.979T>C (p.Phe327Leu) and c.1559del (p.Leu520Argfs), confirming HPP. …”
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First-line chemotherapy with tislelizumab for patients with extensive-stage small cell lung cancer: a cost-effectiveness analysis by Rong Long, Fangping Chen

“…The ICER was lower than the assumed willingness-to-pay threshold of $35,367 per QALY. Approximately 60% of simulations suggested that tislelizumab in combination with chemotherapy was cost-effective, while 40% suggested that chemotherapy alone was cost-effective. …”
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Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano by Biodun Bintu Adebakin, Mayor Orezime Atima, Ugbede Idakwo, Jamilu Abubakar Bala, Alhasan Sharif Abdullahi, Auwal Bello Muhammad, Jah Douglas Pam, Emeka John Dingwoke, Florence Olufunke Darda

“…The results from these methods were compared with assess their sensitivity, specificity and diagnostic value.Results Funduscopy detected T. gondii in 25.4% (67/264) of the patients, while ELISA showed a higher detection rate of 36.7% (97/264). …”
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Evaluation of efficacy of photodynamic disinfection against enterococcus faecalis and compare it with the effect of different endodontic irrigant activation techniques. by Amanda George Haskiyal, Dara Hamarashid Saeed

“…SEM results indicated that the FotoSan group (5.56±3.16) and Diode laser (5.56±3.57) had the lowest surviving colony mean number. …”
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КОМПОЗИТ НА ОСНОВЕ ПЕНОПОЛИУРЕТАНА И БАЗАЛЬТОВОГО ВОЛОКНА ДЛЯ ИЗГОТОВЛЕНИЯ СЪЕМНЫХ ЧЕХЛОВ С ЦЕЛЬЮ ТЕПЛОИЗОЛЯЦИИ ОБОРУДОВАНИЯ... by Гульнара Ильхамовна Амерханова, Елена Анатольевна Кияненко, Любовь Андреевна Зенитова

“…Так, скорость горения для ненаполненного аналога составила 387 мм/мин, а при наполнении БВ размером 6 мм в количестве 15% мас. привело к снижению данного показателя до 92 мм/мин. …”
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Surgical informed consent practice and associated factors among adult postoperative patients in public hospitals of Mekelle, Tigray, Ethiopia 2023/2024. Cross sectional. by Fiseha Abadi Gebreanenia, Hailemarim Berhe Kahsay, Desta Siyoum Belay, Binyam Gebrehiwet Tesfay, Fissha Brhane Mesele, Mamush Gidey Abirha

“…Educational level [AOR 5.76 (1.02, 32.6)], timing of surgical informed consent delivery [AOR 3.27 (1.5, 7.11)], qualification of counselor who took surgical informed consent them [AOR3.185 (1.21, 8.38)], hospital type [AOR 2.85 (1.26, 6.46)], and duration of counseling [AOR 6.9 (3.33, 14.3)] were statistically significant at P<0.05.…”
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Influenza vaccination hesitancy and related factors among pregnant and breastfeeding women: A cross-sectional study by Dania Comparcini, Giancarlo Cicolini, Melania Totaro, Letizia Governatori, Francesco Pastore, Daniela Miniscalco, Maria Elena Flacco, Eustachio Cuscianna, Silvio Tafuri, Valentina Simonetti

“…Higher educational levels, ongoing pregnancy, already being vaccinated or willingness to get vaccinated, and being employed were associated with reduced vaccine hesitancy, while prior SARS-CoV-2 infection with increased hesitancy. Fear of unpredictable events and lack of healthcare professionals’ recommendations emerged as reasons for vaccine reluctance. …”
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Four Weeks of Inspiratory Muscle Training Improves Self-Paced Walking Performance in Overweight and Obese Adults: A Randomised Controlled Trial by A. M. Edwards, G. P. Maguire, D. Graham, V. Boland, G. Richardson

“…Additionally, the posttraining distance covered in the 6-minute walking test was significantly extended for EXP (62.5±37.7 m gain; 𝑃<0.01), but not for PLA. A positive association was observed between the change (%) of performance gain in the 6-minute walking test and body mass index (𝑟=0.736; 𝑃<0.05) for EXP. …”
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Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics by Wei Lei, Yan Wu, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Huipin Yuan, Mingzheng Li

“…Furthermore, the bone area within the available space of BCP implants increased significantly from 19.3% ± 7.3% at 12 weeks to 37.7% ± 8.5% at 24 weeks (p = 0.0063), accompanied by significant BCP resorption (14.8% at 12 weeks and 30.2% at 24 weeks). …”
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Geriatric Trauma Outcome Score for Predicting Mortality among Older Korean Adults with Trauma: Is It Applicable in All Cases? by Jonghee Han, Su Young Yoon, Junepill Seok, Jin Young Lee, Jin Suk Lee, Jin Bong Ye, Younghoon Sul, Se Heon Kim, Hong Rye Kim

“…Results Among 3,053 patients, the median age was 77 years, and the mortality rate was 5.2%. The overall GTOS-predicted mortality and 1–TRISS were 5.4% (interquartile range [IQR], 3.7–9.5) and 4.7% (IQR, 4.7–4.7), respectively. …”
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