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48701
Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies
Published 2025-01-01“…The results indicated that Compared with the lowest TyG-BMI index category, the highest TyG-BMI index was related to a higher incidence of cardiovascular diseases (CVD) (HR = 1.62; 95% confidence interval (CI): 1.35–1.95; I2 = 94%),coronary artery disease (CAD) (HR = 1.69; 95% (CI): 1.23–2.31; I2 = 94%). stroke(HR = 1.57; 95% (CI): 1.11–2.23; I2 = 94%).In the dose–response analysis, there was a linear association of the TyG-BMI index with the risk of CVD (Pnonlinear = 0.223), CAD (Pnonlinear = 0.693), and stroke (Pnonlinear = 0.122)No significant effects were observed regarding participants’ gender, length of follow-up, sample size or mean age(P > 0.05). …”
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48702
Serum NFL and neuropsychological performance over ∼8 years in women with and without HIV: a longitudinal repeated measures studyResearch in context
Published 2025-02-01“…Multivariable linear regression analyses stratified by HIV serostatus examined cross-sectional baseline and follow-up associations, and ∼8-year change in sNFL level related to global and domain-specific NP T-scores. Findings: 417 participants (290 WLWH, 127 WLWOH), African American/Black (55%), ≥high school education (69%), current/former smokers (79%), and overweight/obese (BMI ≥25.0 kg/m2, 74%) were included. …”
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48703
Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group
Published 2024-12-01“…A total of 408 primary IgAN patients treated with IST (65.4% male, mean age 38.4 ± 12.5 years, follow-up 30 (3–218) months) were included and divided into two groups according to treatment protocols (isolated corticosteroid [CS] 70.6% and combined IST 29.4%). Treatment responses, associated factors were analyzed.Results Remission (66.7% partial, 33.7% complete) was achieved in 74.7% of patients. …”
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48704
انگشتنگاری منابع رسوب تهنشین شده در بستر رودخانه با استفاده از ردیابهای ژئوشیمیایی و مدل ترکیبی در حوضهای با فرسایش خندقی شدید...
Published 2023-09-01“…نتایج و بحث طبق نتایج بهدست آمده، 16.7 درصد سهم رسوبات مورد بررسی مربوط به کاربری کشاورزی، 50.6 درصد مربوط به خندق و 32.7 درصد مربوط به کاربری مرتع و بایر است. …”
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48705
First Detection of <i>Alphacoronavirus</i> in Bats from the World’s Largest Wetland, the Pantanal, Brazil
Published 2025-01-01“…Orthocoronavirinae was detected in 16.7% (70/419) of the bats; nine samples were sequenced, confirming that <i>Carollia perspicillata</i> (4), <i>Phyllostomus hastatus</i> (2), <i>Desmodus rotundus</i> (1), <i>Molossus rufus</i> (1), and <i>Myotis</i> cf. …”
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48706
Convergent construct validity and test-retest reliability of both German versions of the original and the revised Niigata PPPD Questionnaire: NPQ and NPQ-R
Published 2025-01-01“…Internal consistency, test-retest reliability, SEM and MDC calculated for NPQ/NPQ-R were α = 0.88/α = 0.91, ICC=0.83 (CI 0.77 to 0.0.87), SEM 5.55/8.37, and MDC 15/23 points.ConclusionThe German versions of NPQ and NPQ-R are valid and reliable patient-reported outcome measures for assessing PPPD, demonstrating satisfactory psychometric measurement properties including convergent construct validity and reliability parameters: internal consistency, test-retest reliability, SEM, and MDC as an evaluative measure. …”
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48707
β-淀粉样蛋白对叉头蛋白O3a和突触后致密蛋白95的影响
Published 2021-09-01“…结果与正常对照组相比,20 μmol/L的Aβ<sub>25-35</sub>处理组PSD95蛋白水平下调至(45.09±1.61)% (<italic>F</italic>=7.487, <italic>P</italic>=0.0540)。与之对应,20 μmol/L的Aβ<sub>25-35</sub>上调FoxO3a的蛋白水平为对照组的(228.7±20.44)% (<italic>F</italic>=17.48, <italic>P</italic>=0.021 0)。…”
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48708
Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio
Published 2025-01-01“…Suboptimal physiological outcome post-PCI was identified in 24.7% (199 of 806) of vessels and post-PCI μQFR <0.90 was associated with higher risk of 2-year target vessel failure (6.1% [12 of 199] vs 2.7% [16 of 607]; HR: 2.45 [95% CI: 1.14-5.26]; P = 0.022). …”
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48709
Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context
Published 2025-02-01“…Pedigree-heritability of psychotic MDD was 30.17% (95% CI 23.53–36.80%). While the genetic correlation between psychotic and non-psychotic MDD was high (0.82, 95% CI 0.73–0.92), the psychotic subgroup showed a higher genetic correlation with schizophrenia than non-psychotic MDD (0.67 vs 0.46, p-value 7.55∗10−4). …”
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48710
Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysisResearch in context
Published 2025-01-01“…Compared to no treatment or placebo, antiparasitic treatment led to a reduction in i) ECG changes (17 studies, 4994 participants: risk ratio (RR): 0.48, 95% CI 0.36–0.66, p < 0.001; I2 = 76.4%) with a number needed to treat (NNT) of 5; ii) disease progression (12 studies, 5722 participants: RR: 0.35, 95% CI 0.23–0.51, p < 0.001; I2 = 72.4%) NNT of 6; iii) cardiovascular death (7 studies, 5662 participants: RR: 0.44, 95% CI 0.21–0.95, p = 0.04; I2 = 50.5%) NNT of 22; and iv) overall mortality (10 studies, 7694 participants: RR: 0.54, 95% CI 0.34–0.87, p < 0.001; I2 = 60%) NNT of 23. …”
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48711
Soil smoldering in temperate forests: a neglected contributor to fire carbon emissions revealed by atmospheric mixing ratios
Published 2025-01-01“…As a result, the carbon emissions from the 2022 fires in France amounted to 7.95 MtCO<span class="inline-formula"><sub>2</sub></span>-eq (<span class="inline-formula">±3.62</span>). …”
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48712
Panitumumab versus cetuximab in combination with irinotecan in refractory metastatic colorectal cancer
Published 2024-01-01“…There was no significant difference in median overall survival between treatment groups (9.1 months [I + C] vs 10.1 months [I + P]; p = 0.76). There was also no difference in progression-free survival (3.63 months [I + C] vs 3.73 months [I + P]; p = 0.19) and objective response rate (23.0 % [I + C] vs 22.3 % [I + P]; p = 0.97). …”
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48713
Bridging the gap: challenges and adoption of climate-resilient agriculture technologies in agricultural landscapes across agro-climatic zones of Bihar, India
Published 2025-01-01“…Targeted efforts in these areas can significantly increase the adoption of the CRATs, leading to more resilient and sustainable farming systems. …”
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48714
Muzyka i wolnomularstwo warszawskie na początku XIX wieku. Kilka nowych informacji dotyczących wolnomularskiej działalności Józefa Elsnera (ze zbiorów archiwum masońskiego w AGAD)...
Published 2024-11-01“…Kilka spośród zebranych w wyborze pieśni tego kompozytora znajduje się w zbiorach AGAD w postaci rękopiśmiennych kopii, co odnotowano w prezentowanym artykule. …”
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48715
Optimizing Prescribing for Individuals With Type 2 Diabetes and Chronic Kidney Disease Through the Development and Validation of Algorithms for Community Pharmacists
Published 2025-01-01“…The overall S-CVI/Ave across 3 rounds was 0.97. The overall percentage of participants across 3 rounds who agreed or strongly agreed to 5 face validity statements ranged from 83% to 100%, which was above the prespecified threshold for face validity consensus. …”
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48716
Investigation of GAM zonal flows near the pedestal region of H-mode on EAST tokamak
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48717
Towards a high-quality in situ observation network for oxygenated volatile organic compounds (OVOCs) in Europe: transferring metrological traceability to the field
Published 2025-01-01“…For the working standards based on certified spiked whole-air samples in pressurised cylinders, results showed a good agreement among the laboratories (i.e. differences within the measurement expanded uncertainty (<span class="inline-formula"><i>U</i></span>) ranging between 0.5 and 3.3 <span class="inline-formula">nmol mol<sup>−1</sup></span>) and with the certified amount of substance fraction for acetaldehyde (15.7 nmol mol<span class="inline-formula"><sup>−1</sup></span> <span class="inline-formula">±</span> 3.6 (<span class="inline-formula"><i>U</i></span>) nmol mol<span class="inline-formula"><sup>−1</sup></span>), acetone (17 nmol mol<span class="inline-formula"><sup>−1</sup></span> <span class="inline-formula">±</span> 1.5 (<span class="inline-formula"><i>U</i></span>) nmol mol<span class="inline-formula"><sup>−1</sup></span>) and MEK (12.3 nmol mol<span class="inline-formula"><sup>−1</sup></span> <span class="inline-formula">±</span> 2.3 (<span class="inline-formula"><i>U</i></span>) nmol mol<span class="inline-formula"><sup>−1</sup></span>). …”
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48718
Supercharged nanoadhesive through co-assembly of recombinant protein and tetrahedral DNA for corneal transplantation
Published 2025-01-01“…To address this, we developed a novel cornea-specific nanoadhesive constructed through protein-DNA co-assembly and applied it to corneal transplantation. …”
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48719
Associations of sociodemographic and smoking characteristics with intention to quit among Chinese adults aged 20–69 years who smoke: Findings from nationwide China Health Literacy...
Published 2025-01-01“…ItQ was significantly associated with smoking characteristics, including occasional smoking (OR = 2.08, 95 % CI = 1.88–2.20), fewer pack-years (OR = 0.70, 95 % CI = 0.68–0.73), older smoking initiation age (OR = 1.22, 95 % CI = 1.18–1.27), and ICD-10 Nicotine dependence (OR = 1.12, 95 % CI = 1.06–1.19), as well as age, sex, socioeconomic factors, and health status. …”
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48720
Dacostaite, K(Mg<sub>2</sub>Al)[Mg(H<sub>2</sub>O)<sub>6</sub>]<sub>2</sub>(AsO<sub>4</sub>)<sub>2</sub>F<sub>6</sub>  ⋅  2H<sub>2</sub>O, a new fluoride–arsenate mi...
Published 2025-01-01“…The empirical formula of dacostaite, based on (As <span class="inline-formula">+</span> P) <span class="inline-formula">=</span> 2 atoms per formula unit, is (K<span class="inline-formula"><sub>0.56</sub></span>Ca<span class="inline-formula"><sub>0.04</sub></span>Na<span class="inline-formula"><sub>0.03</sub>□<sub>0.37</sub></span>)<span class="inline-formula"><sub>Σ1.00</sub></span> (Al<span class="inline-formula"><sub>1.54</sub></span>Mg<span class="inline-formula"><sub>1.38</sub></span>Cu<span class="inline-formula"><sub>0.03</sub></span>Zn<span class="inline-formula"><sub>0.03</sub></span>)<span class="inline-formula"><sub>Σ2.98</sub></span> [Mg(H<span class="inline-formula"><sub>2</sub></span>O)<span class="inline-formula"><sub>6</sub></span>]<span class="inline-formula"><sub>2</sub></span> [(As<span class="inline-formula"><sub>0.99</sub></span>P<span class="inline-formula"><sub>0.01</sub>)</span>O<span class="inline-formula"><sub>4</sub></span>]<span class="inline-formula"><sub>2</sub></span> [F<span class="inline-formula"><sub>4.46</sub></span>(OH)<span class="inline-formula"><sub>1.46</sub></span>O<span class="inline-formula"><sub>0.08</sub></span>]<span class="inline-formula"><sub>Σ6.00</sub></span> <span class="inline-formula">⋅</span> 2H<span class="inline-formula"><sub>2</sub></span>O (<span class="inline-formula"><i>Z</i>=2</span>). …”
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