High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa by Yan Yang, Xue Li, Lang Sun, Xiu-Kun Wang, You-Wen Zhang, Jing Pang, Guo-Qing Li, Xin-Xin Hu, Tong-Ying Nie, Xin-Yi Yang, Jian-Hua Liu, Gerrit Brandis, Xue-Fu You, Cong-Ran Li

“…The study found that the oprD Trp415* allele alone accounts for the imipenem MIC in clinical isolates, while the ∆mexR and ftsI Arg504Cys alleles do not contribute to imipenem resistance. …”
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A systematic scoping review of clinical indications for induction of labour. by Dominiek Coates, Angela Makris, Christine Catling, Amanda Henry, Vanessa Scarf, Nicole Watts, Deborah Fox, Purshaiyna Thirukumar, Vincent Wong, Hamish Russell, Caroline Homer

“…For women with preterm premature rupture of membranes (24-37 weeks), high-quality evidence supports expectant management rather than IOL/early birth. …”
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LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy by Zhishui Chen, Gang Chen, Li Chen, Xiangli Zhao, Lingjuan Sun, Zhibo Ma, Xiaosheng Tan, Yuhao Tu, Jingzeng Wang, Peixiang Lan

“…In an in vivo setting, we employed male C57BL/6J injected with B16 cells or MC38 cells to build a tumor model to assess the effects of LDL and LRP11 inhibitors, LRP11 activators, MAPK13 inhibitors on tumor growth. …”
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Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis by Roberto Buonaiuto, Aldo Caltavituro, Margherita Tafuro, Alessandra Longobardi, Giuliana Pavone, Pierluigi De Santis, Roberta Caputo, Carmine De Angelis, Lucia Del Mastro, Fabio Puglisi, Mario Giuliano, Grazia Arpino, Martina Pagliuca, Michelino De Laurentiis

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miR-96-5p靶向叉头状转录因子O1对Ishikawa细胞的作用 by 冯艳奇, 张娥, 张蕾, 郝颂华, 倪婷婷

“…转染pcDNA、pcDNA-FOXO1、inhibitor NC、miR-96-5p inhibitor、miR-96-5p mimic、miR-96-5p + FOXO1到子宫内膜癌Ishikawa细胞，分别记为pcDNA组、FOXO1组、inhibitor NC组、miR-96-5p inhibitor组、miR-96-5p组、miR-96-5p + FOXO1组，对照组不进行转染。取稳定转染的各组细胞，CCK-8和Transwell小室检测细胞活力和侵袭能力，Western blot检测细胞周期蛋白D1（Cyclin D1）、活化多聚ADP核糖聚合酶（cleaved PARP）、p21及波形蛋白的表达水平。…”
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Is maternal diabetes during pregnancy associated with neurodevelopmental, cognitive and behavioural outcomes in children? Insights from individual participant data meta-analysis in... by Rachelle A. Pretorius, Demetris Avraam, Mònica Guxens, Jordi Julvez, Jennifer R. Harris, Johanna Thorbjornsrud Nader, Tim Cadman, Ahmed Elhakeem, Katrine Strandberg-Larsen, Hanan El Marroun, Serena Defina, Tiffany C. Yang, Rosie McEachan, John Wright, Jesús Ibarluzea, Loreto Santa-Marina, Juana Mari Delgado, Marisa Rebagliato, Marie-Aline Charles, Chloe Vainqueur, Silvia Maritano, Daniela Zugna, Wen Lun Yuan, Barbara Heude, Rae-Chi Huang

“…Results Children (aged 7–10 years) born to mothers with GDM had higher attention-deficient hyperactive disorder (ADHD) symptoms compared to non-exposed controls (model 2, regression coefficient (β) 3.67 (95% CI 1.13, 6.20), P = 0.001). …”
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CT-based intratumoral and peritumoral radiomics nomogram to predict spread through air spaces in lung adenocarcinoma with diameter ≤ 3 cm: A multicenter study by Yangfan Su, Junli Tao, Xiaosong Lan, Changyu Liang, Xuemei Huang, Jiuquan Zhang, Kai Li, Lihua Chen

“…Center I included 525 patients (368 in the training cohort and 157 in the validation cohort); center II included 115 patients (the test cohort). …”
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Synthesis of silver Nanoparticles@Carbon Dot nanocomposites using Aegle marmelos and Euphorbia hirta: Anti vibriocidal and antioxidant properties by Gali Raman, Sirangu Joseph, D Ramachandran, Phanindra Babu Kasi, Abhinash Marukurti, Alavala Matta Reddy, P Vijaya Nirmala, V S Manikanta, R. Lohitha Kavya, K Sarojani, Anitha Kadimi, Silpa Rani Medapalli, S B Sonia Shankar, G Dinesh Ratna, K Gayathri, P Tirupathi Rao

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Derivation of allometric equations and carbon content estimation in mangrove forests of Malaysia by Waseem Razzaq Khan, Michele Giani, Stanislao Bevilacqua, Shoaib Ahmad Anees, Kaleem Mehmood, M. Nazre, Abdul Aziz Bin Abdul Haddy, Abang Norizan Bin Abang Median, Japanie Bin Bujang, Fatin-Norliyana Mohamad-Ismail, Johar Mohamed, Zaiton Samdin, Rambod Abiri, Tuan-Marina Tuan-Ibrahim, Lydia-Suzieana Mohammad, Hamid-Reza Naji, Seemab Akram, Hazandy Abdul-Hamid, Timothy Dube

“…The total aboveground biomass ranged from 183.30 t ha⁻1 to 187.06 t ha⁻1 across the study area. We calculated the total carbon stock at 91.01 t C ha⁻1, incorporating measurements from trees below 5 cm in diameter, dead and downed wood, and litter. …”
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Clostridioides difficile infection and recurrence in cancer patients (CIRCA): A multicentre, international study by Pedro Puerta-Alcalde, Jessica O'Keefe, Rachel Woolstencroft, Shipraa Kaul, Néstor López, Katie Cronin, Andrew Lim, Nicole Garcia-Pouton, Míriam Álvarez, Lynette Chee, Mateu Espasa, Ignacio Grafia, Maria Suárez-Lledó, Olivia Smibert, Carolina Garcia-Vidal, Monica A. Slavin, Michelle K. Yong, Alex Soriano, Leon J. Worth

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Din Kültürü ve Ahlak Bilgisi Öğretmenleri ve İmam Hatip Lisesi Meslek Dersi Öğretmenlerinin İş Tatmini Düzeyleri by İrfan Sevinç

“…Ölçeğin Cronbach Alfa değeri 0,77’dir. Ölçek içsel ve dışsal iş tatmin olarak iki alt boyut ve toplam 20 maddeden oluşmaktadır. …”
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Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere by R. Jin, W. Hu, W. Hu, P. Duan, M. Sheng, D. Liu, Z. Huang, M. Niu, L. Wu, J. Deng, P. Fu, P. Fu

“…Bacterial strains produced more abundant CHONS compounds (25.2 %), while fungal exometabolites were rich in CHO compounds (31.7 %). These microbial exometabolites predominantly comprised aliphatic/peptide-like and carboxyl-rich alicyclic molecule (CRAM)-like compounds. …”
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Diagnostic value of dual-layer spectral detector CT parameters for differentiating high- from low-grade bladder cancer by Li Chen, Lili Xu, Xiaoxiao Zhang, Jiahui Zhang, Xin Bai, Qianyu Peng, Erjia Guo, Xiaomei Lu, Shenghui Yu, Zhengyu Jin, Gumuyang Zhang, Yi Xie, Huadan Xue, Hao Sun

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The PANORAMIC Survey: Pure Parallel Wide Area Legacy Imaging with JWST/NIRCam by Christina C. Williams, Pascal A. Oesch, Andrea Weibel, Gabriel Brammer, Aidan P. Cloonan, Katherine E. Whitaker, Laia Barrufet, Rachel Bezanson, Rebecca A. A. Bowler, Pratika Dayal, Marijn Franx, Jenny E. Greene, Anne Hutter, Zhiyuan Ji, Ivo Labbé, Sinclaire M. Manning, Michael V. Maseda, Mengyuan Xiao

“…The ≳6-filter strategy yields remarkably good photometric redshift performance, achieving similar median scatter and outlier fraction as CANDELS ( σ _NMAD ∼ 0.07; η ∼ 0.2), enabling a wealth of science across redshift without need for follow-up or ancillary data. …”
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Artificial intelligence-enhanced comprehensive assessment of the aortic valve stenosis continuum in echocardiographyResearch in context by Jiesuck Park, Jiyeon Kim, Jaeik Jeon, Yeonyee E. Yoon, Yeonggul Jang, Hyunseok Jeong, Youngtaek Hong, Seung-Ah Lee, Hong-Mi Choi, In-Chang Hwang, Goo-Yeong Cho, Hyuk-Jae Chang

“…Findings: The DL index for the AS continuum (DLi-ASc, range 0–100) increased with worsening AS severity and demonstrated excellent discrimination for any AS (AUC 0.91–0.99), significant AS (0.95–0.98), and severe AS (0.97–0.99). DLi-ASc was independent predictor for composite endpoint (adjusted hazard ratios 2.19, 1.64, and 1.61 per 10-point increase in ITDS, DHDS, and TDDS, respectively). …”
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Practice patterns among early-career primary care (ECPC) physicians and workforce planning implications: protocol for a mixed methods study by Richard J Gibson, Tara Sampalli, Tara Kiran, Richard H Glazier, Agnes Grudniewicz, Kimberlyn McGrail, David Snadden, Ian Scott, M Ruth Lavergne, Laurie J Goldsmith, David Rudoler, Emily Gard Marshall, Megan Ahuja, Doug Blackie, Fred Burge, Steve Hawrylyshyn, Lindsay Hedden, Jacalynne Hernandez-Lee, Kathleen Horrey, Mike Joyce, Adrian MacKenzie, Maria Mathews, Rita McCracken, Madeleine McKay, Charmaine McPherson, Goldis Mitra, Gail Tomblin Murphy, Sabrina T Wong

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Acupoint application of Xiefu prescription in the prevention of functional constipation in long-term bedridden patients with pelvic fracture (泻腑贴方穴位贴敷预防长期卧床骨盆骨折患者功能性便秘的临床研究)... by GU Tianjiao (顾天姣), LIU Yingchun (刘迎春), DONG Ziqing (董子青), DING Di (丁娣), DENG Lixia (邓丽霞), YANG Yanhui (杨燕辉), MAO Lingling (毛玲玲)

“…方法 选取既往排便功能无异常且便秘主要症状评分≤3分的单纯骨盆骨折患者60例, 随机分为两组: 对照组(n=30)接受便秘常规预防护理, 治疗组(n=30)在对照组基础上增加泻腑贴方穴位贴敷。于入院当天、卧床第7、14天, 记录便秘主要症状评分, 并记录卧床14d内辅助排便措施介入情况。结果 卧床第7、14天治疗组便秘主要症状总分低于对照组, 差异有统计学意义(P＜0. 01); 卧床第14天治疗组粪便性状、排便费力、排便时间、下坠/不尽/胀感、排便频率、腹胀条目得分低于对照组, 差异有统计学意义(P<0. 01)。…”
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La datation des aqueducs lyonnais : un état des lieux by Aldo Borlenghi, Catherine Coquidé

“…This study picks up and analyses all the arguments used to support one or the other of these dates: the link between the remains of the hill’s water supply network under Augustus and the altitude of arrival of the aqueduct; pipes stamped with the TI · CL · CAES · brand found in the 18th century on Colline de Fourvière; the aqueduct’s protective boundary stones bearing the name of Emperor Hadrian; the attested stamps on the bipedal bricks of the arch and bridge piers; the opus reticulatum mixtum construction technique; the fountain at the enclosure of the fountain at the Verbe Incarné enclos and its water supply; radiocarbon and archaeomagnetic dating. …”
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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…After adjusting for age, sex, hypertension, diabetes, atrial fibrillation, administration of intravenous thrombolysis (IVT), Alberta Stroke Program Early CT Scores (ASPECTS), mTICI 2c and/or 3, Tmax >6 s volume, and hemorrhagic transformation, PVT+ was significantly associated with lower NIHSS percent change (B = −0.163, 95%CI −0.326 to −0.001, p = 0.049) and was less likely to achieve higher than 70% NIHSS improvement (OR = 0.331, 95% CI 0.127–0.863, p = 0.024). …”
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RECUPERACIÓN DE ESPACIOS URBANOS Y PERIURBANOS MEDIANTE LA IMPLEMENTACIÓN DE PARQUES-HUERTAS EN LA CIUDAD DE BAHIA BLANCA by Jezabel Franza, María Kraser, Daniel Paoloni, Silvina Raitzin, Gabriel Reiter

“…Las ciudades crecen y generan espacios con profundos desequilibrios. Desde la acción pública existen diferentes formas de abordar esta complejidad. …”
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