Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan by Kaori Mukai, Robert Cost, Xin Sheen Zhang, Emily Condiff, Joanne Cotton, Xiaohua Liu, Ekaterina Boudanova, Björn Niebel, Peter Piepenhagen, Xinming Cai, Anna Park, Qun Zhou

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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Di Shen,1,* Xintian Cai,2,* Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. …”
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Unique ultrastructural organization of human rod photoreceptors by Tylor R. Lewis, Natalia V. Klementieva, Sebastien Phan, Carson M. Castillo, Keun-Young Kim, Lauren Y. Cao, Mark H. Ellisman, Vadim Y. Arshavsky, Oleg Alekseev

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EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…Consequently, an integrated transcriptomic analysis is necessary to fully elucidate the role of NAT10-mediated ac4C modifications in CRC progression. Methods NAT10 expression levels were analyzed in CRC samples and compared with those in corresponding normal tissues. …”
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Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers‐Based Model by Maria Colomba Comes, Annarita Fanizzi, Samantha Bove, Luca Boldrini, Agnese Latorre, Deniz Can Guven, Serena Iacovelli, Tiziana Talienti, Alessandro Rizzo, Francesco Alfredo Zito, Raffaella Massafra

“…Materials and Methods Imaging data analyzed in this study referred to a cohort of 86 breast cancer patients, randomly split into training and test sets at a ratio of 8:2, who underwent NAC and for which information regarding the pCR status was available (37.2% of patients achieved pCR). …”
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Changes in flavor profile of sauce-flavor baijiu: Perceptual interactions between 1-propanol and aroma compounds by Han Zhao, Li-Juan Chai, Wei Zhang, Xiao-Juan Zhang, Zhen-Ming Lu, Song-Tao Wang, Cai-Hong Shen, Jin-Song Shi, Zheng-Hong Xu

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Comparison of inductively coupled plasma mass spectrometry and molybdenum blue colorimetry for total phosphorus determination in freshwater invertebrates. by Molly S Costanza-Robinson, Baker J Angstman, Qiting Cai, Charles Forbes, Julia S Keon, Shuyi Lin, Emma D Neill, Elizabeth G Peebles, Ella Roelofs, Eric K Moody

“…Similarly, analysis of P spike recoveries by ICP-MS (100.2 ± 3.4%) and MBC (107.0 ± 2.8%) were both considered acceptable. We conclude that ICP-MS represents a reliable and comparable alternative to MBC for determining total P in freshwater invertebrates while also offering the opportunity to measure additional biologically relevant elements in a single analysis.…”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

“…Primary outcomes included changes in inflammatory markers (white blood cell count, C-reactive protein, and procalcitonin), imaging outcomes (resolution of pleural effusion, pulmonary inflammation, and the incidence of pleural thickening at three months), pulmonary function assessed by forced vital capacity (FVC), and in-hospital mortality. …”
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The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome by Filiz Yarsilikal Guleroglu, Ali Cetin, Goknil Pelin Coskun, Meltem Caliskan, Fulya Karaduman, Can Bilginer, Resat Misirlioglu, Sinem Tekin, Merve Nur Al, Tugce Caklili, Yusuf Tutar

“…Methods This prospective case-control study involved 26 healthy pregnant women and 17 with placental syndrome. Blood samples were collected from maternal, uterine venous, and umbilical cord veins. …”
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Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p by Li T, Zhao Y, Cao Z, Shen Y, Chen J, Huang X, Shao Z, Zeng Y, Chen Q, Yan X, Li X, Zhang Y, Hu B

“…Ting Li,1,2,* Yuechu Zhao,3,* Zhi Cao,2,* Ying Shen,2 Jiaqi Chen,2 Xinran Huang,2 Zhuang Shao,2 Yi Zeng,2 Qi Chen,2 Xiaofei Yan,3 Xin Li,1,2 Yuelin Zhang,1,2 Bei Hu1,2 1School of Medicine, South China University of Technology, Guangzhou, Guangdong, People’s Republic of China; 2Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 3Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuelin Zhang; Bei Hu, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, 510080, People’s Republic of China, Tel +86-20-83827812-20974, Email zhangyuelin1999@163.com; qhubei@hotmail.comBackground: Exosomes sourced from mesenchymal stem cells (MSC-EXOs) have become a promising therapeutic tool for sepsis-induced myocardial dysfunction (SMD). …”
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Association of valproate use and hippocampal atrophy in idiopathic generalized epilepsy by Xiang Huang, Yingying Zhang, Qiuxing Lin, Kailing Huang, Yuming Li, Peiwen Liu, Danyang Cao, Wenhao Li, Wei Li, Xiuli Li, Qiyong Gong, Dong Zhou, Dongmei An

“…Methods: A total of 211 patients with IGE and 97 healthy controls (HCs) were enrolled in this study. …”
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Correction: An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein dairy cows by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

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Machine Learning Models of Acute Kidney Injury Prediction in Acute Pancreatitis Patients by Cheng Qu, Lin Gao, Xian-qiang Yu, Mei Wei, Guo-quan Fang, Jianing He, Long-xiang Cao, Lu Ke, Zhi-hui Tong, Wei-qin Li

“…The AUC of logistic regression analysis was 87.28%. Present findings suggest that compared to the classical logistic regression model, machine learning models using features that can be easily obtained at admission had a better performance in predicting AKI in the AP patients.…”
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Synthesis and characterization of zinc oxide nanoparticles-carbon composite derived from pineapple peel wastes for adsorption of methylene blue from solution and photocatalytic act... by Salsa Putri Alzura, Vienna Saraswaty, Safri Ishmayana, Yudha Prawira Budiman, Diana Rakhmawaty Eddy, Evyka Setya Aji, Diah Ratnaningrum, Een Sri Endah, Hanny Meirinawati, Henry Setiyanto

“…The ZnONPs/PPWB composite biosorbent was prepared through a facile green synthesis of zinc oxide nanoparticles utilizing pineapple peel wastes as the source of reducing agent and carbon sources, followed by a calcination at a low temperature of 400 °C for 2 h. The properties of the prepared composite biosorbent were characterized using Brunauer-Emmet-Teller (BET) surface area, scanning electron microscopy (SEM), X-ray diffraction (XRD) and fourier transform infra-red (FTIR) analyses. …”
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Ruthenium(II) Lipid‐Mimics Drive Lipid Phase Separation to Arouse Autophagy‐Ferroptosis Cascade for Photoimmunotherapy by Yue Zheng, Wen‐Jin Wang, Jing‐Xin Chen, Kun Peng, Xiao‐Xiao Chen, Qing‐Hua Shen, Bing‐Bing Liang, Zong‐Wan Mao, Cai‐Ping Tan

“…Meanwhile, the peroxidation of polyunsaturated lipids occurs due to the deactivation of glutathione peroxidase 4 (GPX4) and the overexpression of acyl‐CoA synthetase long‐chain family member 4 (ACSL4), leading to the immunogenic ferroptosis. …”
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Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption by Yue Xu, Xiuying Xiao, Chunxiao Ma, Ziyi Wang, Wenxin Feng, Hanyu Rao, Wei Zhang, Ningyuan Liu, Rebiguli Aji, Xiangjun Meng, Wei‐Qiang Gao, Li Li

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A multilayered regulatory network mediated by protein phosphatase 4 controls carbon catabolite repression and de-repression in Magnaporthe oryzae by Zhicheng Huang, Qing Wang, Yan Li, Pengyun Huang, Jian Liao, Jing Wang, Hui Li, Yingying Cai, Jiaoyu Wang, Xiaohong Liu, Fu-Cheng Lin, Jianping Lu

“…Phosphorylation-mediated activation or inactivation of CreA and Crf1 drives CCR and CCDR, thereby governing the metabolism of carbon sources derived from plant cell walls and contributing to fungal pathogenicity. …”
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Scalable temporal multiplexing of telecom photons via thin-film lithium niobate photonics by Çağın Ekici, Yonghe Yu, Jeremy C. Adcock, Alif Laila Muthali, Mujtaba Zahidy, Heyun Tan, Zhongjin Lin, Hao Li, Leif K. Oxenløwe, Xinlun Cai, Yunhong Ding

“…Our time-multiplexed source, operating at a rate of 62.2 MHz, enhances single-photon probability by a factor of 3.37 ± 0.05 without introducing additional multi-photon noise. …”
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Thrombotic vs. Bleeding Events of Interruption of Dual Antiplatelet Therapy within 12 Months among Patients with Stent-Driven High Ischemic Risk Definition following PCI by Hao-Yu Wang, Bo Xu, Chen-Xi Song, Chang-Dong Guan, Li-Hua Xie, Yan-Yan Zhao, Zhong-Xing Cai, Sheng Yuan, Ke-Fei Dou

“…This difference was driven mainly by all-cause death (1.8% vs. 0.7%) and MI (1.3% vs. 0.5%). Furthermore, the rate of net adverse clinical events (4.9% vs. 3.2%; Cox-adjusted HR: 1.581 [1.128–2.216]; PS matching-HR: 1.639 [1.075–2.499]; IPTW-adjusted HR: 1.554 [1.110–2.177]) was also higher in patients with DAPT interruption (≤12 months), whereas no significant differences between groups were observed in terms of BARC 2, 3, or 5 bleeding. …”
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The Effect of Weed Control with Pre-Emergence Herbicides on the Yield Level of Mung Bean Yield by Cailing Jing, Junying Wang, Yonghong Wu, Yufan Zhou, Huijun Zhu, Yaowen Zhang, Shuqi Dong, Xiaorui Li, Juan Zhao, Junli Cao, Xiangyang Yuan, Xi’e Song

“…In summary, imazethapyr and oxadiazon can effectively control weeds and increase mung bean yield. …”
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