Clinical utility and predictive value of cerebrospinal fluid cell-free DNA profiling in non-small cell lung cancer patients with leptomeningeal metastasis by Sheng-Kai Liang, Wei-Yu Liao, Jin-Yuan Shih, Chia-Lin Hsu, Ching-Yao Yang, Shang-Gin Wu, Yen-Ting Lin, Yueh-Feng Wen, Lun-Che Chen, Yen-Fu Chen, Ya-Fang Chen, Yen-Heng Lin, Chong-Jen Yu

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Depressive symptoms among the oldest-old in China: a study on rural-urban differences by Chaoqun Hu, Qinqin Jiang, Yuan Yuan, Bing Hou, Zhe Zhao, Yijun Liu, Jinhai Sun, Lei Yuan

“…In urban areas, age (90-99: β = -0.583, 95%CI = -1.008 to -0.158), annual income (rich: β = -0.699, 95%CI = -1.368 to -0.029), smoking (yes: β = -0.752, 95%CI = -1.376 to -0.127), exercise (yes: β = -1.447, 95%CI = -1.828 to -1.065), self-rated health status (good: β = -2.994, 95% CI = -3.362 to -2.625) were protective factors against depressive symptoms, and married status (other: β = 1.222, 95%CI = 0.564 to 1.880) were risk factors. …”
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Multidimensional Stability of Planar Traveling Waves for Competitive–Cooperative Lotka–Volterra System of Three Species by Na Shi, Xin Wu, Zhaohai Ma

“…Additionally, for planar traveling waves with speed <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>c</mi><mo>=</mo><msup><mi>c</mi><mo>*</mo></msup></mrow></semantics></math></inline-formula>, we demonstrate their algebraic stability in the form <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>t</mi><mrow><mo>−</mo><mstyle><mfrac><mi>n</mi><mn>2</mn></mfrac></mstyle></mrow></msup></semantics></math></inline-formula>. …”
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Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction by Enriqueta Felip, Paolo Nuciforo, Elena Garralda, Joan Frigola, Ramon Amat, Garazi Serna, Francesco Grussu, Kinga Bernatowicz, Olivia Prior, Marta Ligero, Christina Zatse, Rodrigo Toledo, Manel Escobar, Raquel Perez-Lopez

“…Cox models using aggregated CT-TIME scores from baseline images revealed a statistically significant reduction in the risk of PFS in the pan-cancer cohort (HR 0.62, 95% CI 0.44 to 0.88, p=0.007), and Kaplan-Meier analysis further confirmed substantial differences in PFS between patients with inflamed and uninflamed status (log-rank test p=0.009).Conclusions The signature holds promise for impacting clinical decision-making, pan-cancer patient stratification, and treatment outcomes in immune checkpoint therapies.…”
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Increased Early‐Mortality in Children With Solid Tumors During the COVID‐19 Pandemic in a Middle‐Income Country by Oscar Ramirez, Vivian Piedrahita, Santiago Bolivar, Karina Grillo, Adriana Linares, Carlos Pardo, Martha Piña, Amaranto Suarez, Carlos A. Portilla, Jesus Ardila, Viviana Lotero, Luz A. Urcuqui, Angela Trujillo, Patricia Montenegro, Luis E. Bravo, Paula Aristizabal, VIGICANCER Working Group

“…In the EC, the 6‐month and 24‐month mortality adjusted hazard ratio (aHR) in children with solid tumors was 1.7 (95% CI, 1.1–2.7) and 1.3 (95% CI, 1.0–1.7), respectively, and in children with bone tumors 4.0 (95% CI, 1.2–13.0) and 2.1 (95% CI, 1.2–3.6), respectively. …”
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Effect of seed priming and foliar application of organic liquid manure on germination, growth, yield and quality of late-sown wheat by Okram Ricky Devi, Omvati Verma, Bibek Laishram, S. Anbarasan, Abhijit Debnath, Narinder Panotra, Priyanka Elumle, Sunita T. Pandey, R. Ajaykumar, Samreen

“…Higher harvest index was observed significantly from T7, T3, T2, T12, T1 and T11 (40.6, 39.7, 39.0, 37.9, 37.8 and 37.6%, respectively) as compared with other treatments but at par with each other. …”
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A Promising Approach to Ultra‐Flexible 1 Ah Lithium–Sulfur Batteries Using Oxygen‐Functionalized Single‐Walled Carbon Nanotubes by Junyoung Heo, Jeong‐Won Hong, Ha Won Gu, Junghwan Sung, Dong‐Hee Kim, Jung Hoon Kim, Sung Kang, You‐Jin Lee, Hye Young Choi, Doohun Kim, Kang‐Jun Baeg, Joong Tark Han, Jun‐Woo Park

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Incidence of unintended pregnancies and pregnancy experience among adolescents living with perinatally-acquired HIV in West Africa: a mixed-method study by Désiré Lucien Dahourou, Clément Tisseron, Caroline Yonaba, Joël Djaha, Marie-Sylvie N’Gbeche, Corinne Moh, Kouakou Kouadio, Patricia Nindjin, François Eboua, Belinda Bouah, Karen Malateste, Jean-Claude Azani, Eulalie Kangah, Elisabeth Thio, Philippe Msellati, Julie Jesson, Valériane Leroy, for the IeDEA West-African Collaboration

“…Stratified by age at enrolment, it was 2.2 (95%CI: 0.3–15.5), 7.6 (95%CI: 2.8–20.3), 13.1 (95%CI:5.4–31.4), 11.5 (95%CI: 2.8–45.8) per 100 WY in those aged 14, 15, 16, and 17 years, respectively. …”
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Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Lipoprotein(a) by Frederick Berro Rivera, MD, Sung Whoy Cha, MD, Cruz Linnaeus Louisse, MD, Genquen Philip Carado, MD, John Vincent Magalong, MD, Vincent Anthony Tang, MD, Mary Grace Enriquez, MD, Martha Gulati, MD, MS, Byambaa Enkhmaa, MD, PhD, Neha Pagidipati, MD, MPH, Nishant P. Shah, MD

“…Results: PCSK9i reduced Lp(a) levels on average of −27% (95% CI: −29.8% to −24.1%, P < 0.001). Factors associated with the treatment effect included mean percent change in low-density lipoprotein cholesterol (P = 0.003, beta coefficient 0.34, 95% CI: 0.11-0.57, tau2 = 94.8, R2 = 11.82) and apolipoprotein B (P < 0.002, beta coefficient 0.4, 95% CI: 0.14-0.64, tau2 = 93.68, R2 = 11.86). …”
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术中血浆输注剂量对心脏外科手术患者临床预后的影响 by 李丹丹, 黄国栋, 马伟, 刘怡伶

“…结果最终共有305例心脏外科手术患者纳入研究分析，所有患者术中血浆输注剂量的中位数（四分位间距）为11.11（8.17~19.05）mL/kg，其中高剂量组与低剂量组患者术中血浆输注剂量的中位数（四分位间距）分别为17.78（15.69~20.91）mL/kg和9.52（7.77~11.43）mL/kg，两者差异具有统计学意义（<italic>P</italic>&lt;0.001）。…”
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High-dependency unit care after carotid endarterectomy for asymptomatic stenosis by Beatriz Guimarães, Andreia Coelho, Marina Dias-Neto, Ricardo Castro-Ferreira, João Peixoto, Luís Fernandes, Roberto Boal, Marta Machado, Francisco Basílio, Patrícia Carvalho, Armando Mansilha, Alexandra Canedo

“…RESULTS: A total of 51 procedures were included (86.3% male; 69.2±7.9 years) and 11 (21.6%) presented with the CO. …”
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Effect of Dietary Vitamin C Ascorbic Acid on the Growth Performance and Immune Response of Betok Anabas testudineus Bloch by . Sunarto, . Suriansyah, . Sabariah

“…Hasil penelitian menunjukkan bahwa kelangsungan hidup ikan meningkat dengan meningkatnya kadar C dalam pakan.  Jumlah ikan yang mati dalam uji stres adalah 10 pada kontrol, 7 pada perlakuan 125 mg/kg, 5 ekor pada perlakuan 250 mg/kg dan 3 ekor pada perlakuan 375 mg/kg.  …”
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Inorganic constituents in cassava derivatives: Total concentration, dietary intake and bioaccessibility by Leilane R. Santos, Filipe B. Santana, Hilária F.A. Silveira, Wellington C. de Carvalho, Laís A. Souza, Rennan Geovanny O. Araujo, Maria Graças A. Korn, Daniele Cristina M.B. Santos

“…The concentration ranges (in ng g-1) obtained were: As (<12 - 158), Cd (<9 - 47), Co (<17 - 295), Cu (<90 - 1159), Mn (70 - 2523), Pb (<14 - 521), Se (<16 - 215), V (<6 - 106) and Zn (<3208 - 7277). …”
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High-selenium exposure is associated with modulation of serum lipid metabolism by Yong Tan, Zixiong Zhang, Jinru Yang, Li Wang, Guogen Sun, Yishan Guo, Ying Xiang, Yi Zou, Xiusheng Song, Minglong Li, Chuying Huang

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Home Sweet Home: A Program Report on Promoting the Uptake of Home Dialysis by Lucas James Churchill, Frances Reintjes, Robert Pauly, Nikhil Shah, Stephanie Thompson

“…At the time of program attendance, 70% of participants had chronic kidney disease (CKD) not requiring dialysis (CKD G4-5ND) and 30% had CKD G5D on facility-based maintenance hemodialysis. …”
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Safety and efficacy of PD-1 inhibitor (sintilimab) combined with transarterial chemoembolization as the initial treatment in patients with intermediate-stage hepatocellular carcino... by Lei Yu, Lan Zhang, Xin Xu, Zheng Wang, Jian Zhou, Jia Fan, Wentao Wang, Zhenggang Ren, Lixing Li, Peiran Huang

“…Median PFS was 8.4 months (95% CI: 4.7 to 19.7) according to both RECIST V.1.1 and mRECIST. …”
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Effect of Early Mobilization on Respiratory and Limb Muscle Strength and Functionality of Nonintubated Patients in Critical Care: A Feasibility Trial by Maria Karoline Richtrmoc, Wagner Souza Leite, Anielle Martins Azevedo, Raissa Farias Correia, Rômulo de Aquino Coelho Lins, Wildberg Alencar Lima, Caio César Araújo Morais, Rodrigo Rios Pereira, Monique Bandeira, Carlos Eduardo Santos Rego Barros, Amina Maria Soares de Lima, Maria Glória Rodrigues-Machado, Daniella Cunha Brandão, Armèle Dornelas De Andrade, Maria Inês Remigio de Aguiar, Shirley Lima Campos

“…All outcomes were significantly improved (pre vs. post values): MIP (43.93 ± 21.95 vs. 54.12 ± 21.68 cmH2O; P<0.001), MEP (50.32 ± 28.65 vs. 60.30 ± 21.23; P=0.002), HGS (25.5 (9.58) vs. 27.5 (9.48); P=0.046), MRC-s (58.52 ± 2.84 vs. 59.47 ± 1.81; P=0.023), FIM (54.4 ± 22.79 vs. 69.48 ± 12.74), ICF-BMS (28.63 ± 16.19 vs. 14.03 ± 11.15), PFIT-s (9.55 ± 2.34 vs. 11.18 ± 1.32) (P<0.001), and FSS-ICU (28.7 ± 9.1 vs. 32.6 ± 5.0; P=0.001). …”
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Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,... by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

“…The prevalence of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) were 27.4% (95% CI: 23.4, 31.8) and 13.3% (95% CI: 10.3, 16.7), respectively. …”
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Symptoms of anxiety, depression, and post-traumatic stress disorder 6 weeks and 6 months after ICU: Six out of 10 survivors affected by E van der Merwe, L Stroud, G Sharp, N van Vuuren, M Mosola, T Fodo, F Paruk

“…Results. The median age of the 107 ICU survivors was 42 years, and half of them were admitted for complications of COVID-19. …”
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Prevalence and determinants of overweight/obesity, elevated blood pressure, and their comorbidities among primary and secondary school students in Guizhou province: a cross-section... by Zhuan WANG, Xiangdong DU, Xin LI, Xiaoqin ZHANG, Xiujuan LU, Xiying PENG

“…The comorbidity rate of overweight/obesity and elevated blood pressure among students differed significantly by economic development region (4.6%, 4.3%, and 4.1% for those from undeveloped, moderately developed, and highly developed regions, respectively; χ2 = 23.679, P < 0.001), gender (4.7% for males and 4.0% for females; χ2 = 55.967, P < 0.001), and educational level (5.1% for senior high school students, 4.8% for junior high school students, and 3.9% for primary school students; χ2 = 118.414, P < 0.001). …”
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