Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T by Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner

“…A strong negative association was found between NAA/tCr and EDSS in the precentral gyrus (Spearman's rank ρ=-0.58, P=.005), and a moderate positive association between mI/NAA and EDSS in the precentral and superior frontal gyri (ρ=0.47, P=.015). …”
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Timber and carbon sequestration potential of Chinese forests under different forest management scenarios by Hui-Ling Tian, Jian-Hua Zhu, Xiang-Dong Lei, Xin-Yun Chen, Li-Xiong Zeng, Zun-Ji Jian, Fu-Hua Li, Wen-Fa Xiao

“…Biomass carbon sequestration (BCS) between 2020 and 2060 in AR forests is predicted to be 36.00 TgC per year. By 2060, the average BCS is predicted to be approximately 140.00–287.56 TgC per year in China's forests, which is mainly owing to arbor forest management. …”
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Direct anterior approach (DAA) vs. conventional approaches in total hip arthroplasty: A RCT meta-analysis with an overview of related meta-analyses. by Philip Lazaru, Simon Bueschges, Nikolai Ramadanov

“…We came to the following results for THA through DAA compared to THA through CAs: operation time (I2 = 92%, p<0.01; fixed: MD = 15.1, 95% CI 13.1 to 17.1; random: MD = 18.1, 95% CI 8.6 to 27.5); incision length (I2 = 100%, p<0.01; fixed: MD = -2.9, 95% CI -3.0 to -2.8; MD = -1.1, 95% CI -4.3 to 2.0); intraoperative blood loss (I2 = 87%, p<0.01; fixed: MD = 51.5, 95% CI 34.1 to 68.8; random: MD = 51.9, 95% CI -89.8 to 193.5); VAS 1 day postoperatively (I2 = 79%, p = 0.03; fixed: MD = -0.8, 95% CI -1.2 to -0.4; random: MD = -0.9, 95% CI -2.0 to 0.15); HHS 3 months postoperatively (I2 = 52%, p = 0.08; fixed: MD = 2.8, 95% CI 1.1 to 4.6; random: MD = 3.0, 95% CI -0.5 to 6.5); HHS 6 months postoperatively (I2 = 0%, p = 0.67; fixed: MD = 0.9, 95% CI -1.1 to 2.9; random: MD = 0.9, 95% CI -1.1 to 2.9); HHS 12 months postoperatively (I2 = 0%, p = 0.79; fixed: MD = 0.7, 95% CI -0.9 to 2.4; random: MD = 0.7, 95% CI -0.9 to 2.4). …”
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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…The total concentrations of Σ15TOPEs, Σ3NOPEs, Σ9Di-OPEs, and Σ7OH-OPEs in surface sediments were 3.16–73.4, n.d.–16.3, 4.48–21.4, and 0.14–0.42 ng g−1, respectively. …”
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Structural Model of Factors Affecting the Use of Organic Fertilizers by Rice Farmers during Rice (Oryza sativa) Cultivation in Dezful County by Zahra Eskanadari, Moslem Saavri, Masoud Yazdanpanah

“…This is despite the fact that the perceived obstacles variable did not have a significant effect in this section. In addition, it can be said that the variables of the health belief framework could explain 67% of the variance of the dependent variable of the research (the use of organic fertilizers in rice cultivation). …”
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Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

“…Although several studies have investigated antimicrobial resistance in G. parasuis, the correlation between phenotypic and genotypic resistance remains unclear due to incomplete genetic resistance mechanisms detection.MethodsThe susceptibility of 117 clinical G. parasuis isolates to 7 antimicrobials was determined using a broth microdilution method. …”
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Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression by Jianfeng Peng, Xueying Zhai, Xiaomei Liu, Zhaoqin Huang, Yimeng Wang, Peizhu Wu, Ran Gao, Xiangjiao Meng

“…The median overall survival (OS) in the IBP group was also longer than that in the non-IBP group (11.2 months vs. 9.0 months, HR=0.68, 95%CI 0.47-0.98, p=0.042). Subgroup analyses revealed a significant survival advantage with IBP treatment in patients presenting with baseline liver metastases, less than three metastatic organs, and those who were nonsmokers. …”
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Zeydîyye Mezhebi, İmamet Anlayışı ve Sahabe Hakkındaki Görüşleri by Mehmet Ümit

“…Çağdaş Zeydî alimler de Zeydî imamlarının sahâbe hakkındaki&nbsp;anlayışlarına paralel bir tutum benimserler.p.p1 {margin: 0.0px 0.0px 0.0px 1.9px; text-align: justify; line-height: 8.1px; font: 8.0px 'Times New Roman'; color: #2f2a2b}p.p2 {margin: 1.8px 0.0px 0.0px 1.9px; text-align: justify; font: 8.0px 'Times New Roman'; color: #2f2a2b}p.p3 {margin: 5.7px 0.0px 0.0px 1.9px; text-align: justify; font: 8.0px 'Times New Roman'; color: #2f2a2b}p.p4 {margin: 0.0px 0.0px 0.0px 1.9px; font: 8.0px 'Times New Roman'; color: #2f2a2b}span.s1 {letter-spacing: 0.2px}span.s2 {letter-spacing: 1.1px}span.s3 {letter-spacing: 0.9px}span.s4 {letter-spacing: 1.0px}span.s5 {letter-spacing: -0.1px}span.s6 {letter-spacing: 2.1px}span.s7 {letter-spacing: 0.8px}span.s8 {letter-spacing: 0.5px}span.s9 {letter-spacing: 0.6px}span.s10 {letter-spacing: -0.8px}span.s11 {letter-spacing: -0.7px}span.s12 {letter-spacing: 1.3px}span.s13 {letter-spacing: 1.4px}span.s14 {letter-spacing: 0.3px}span.s15 {letter-spacing: 0.1px}span.s16 {letter-spacing: 1.5px}span.s17 {letter-spacing: 1.6px}span.s18 {letter-spacing: 1.7px}span.s19 {letter-spacing: 1.8px}span.s20 {letter-spacing: -0.3px}…”
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Spatial Analysis of Building Density and Liquefaction Spread in Izmit Bay and its Surroundings by Arzu Erener, Metin Aşcı, Gül Gülsoy, Aydın Üstün, Muhammed Ali Güvenaltın, Erman Şentürk, Sefa Yalvaç, Fatma Canaslan Çomut, T. Serkan Irmak, Haluk Konak, Pakize Küreç Nehbit, Efdal Kaya, Burak Kotan, Selin Öye

“…Since December 2017, with the support of Kocaeli Metropolitan Municipality and with the leadership of Kocaeli University Geomatic Department, TÜBİTAK project numbered 117Y155 and titled “Monitoring of Vertical Displacements in East Marmara (Izmit Bay) with Multi-Band InSAR and GNSS Techniques, Investigation of the Relationship Between Ground Collapse and Building Density and Liquefaction" studies have been initiated to determine the risks in the Izmit Bay area. …”
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Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort by Sonya Cressman, Louisa Edwards, Kimberlyn McGrail, Stirling Bryan, Alison Hoens, Rohit Vijh, Sandra Peterson, Zeina Waheed, Mary Bunka, Nick Pang, Shahzad Ghanbarian, Gavin Wong, Linda Riches, Jehannine Austin

“…The odds ratio (OR) for health service utilisation between the pharmacotherapy group and the non-pharmacotherapy group for individuals who were recently incident was 8.14 (95% CI 7.40, 8.95) for outpatient physician visits, 1.04 (95% CI 1.02, 1.07) for ED visits and 1.05 (95% CI 1.00, 1.10) for hospitalisations, after adjusting for comorbidities and other sociodemographic variables in our regression analyses, whereas for the actively prevalent group the ORs were 7.57 (7.27, 8.49), 0.91 (0.89, 0.92) and 1.00 (0.98, 1.02), respectively.Conclusion This study examined the association of pharmacotherapy on healthcare utilisation for adults with MDD in BC. …”
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Knowledge, Attitude, and Practice (KAP) Survey toward Skin Cancer among Ecuadorian Population by Victor H. Pinos-León, César Sandoval, Franklin Cabrera, Esmeraldas Terán, Ana Garnica, Ana Kellendonk, Mery Alvear, Carla Rosero, Lorena Vaca, Jorge Bonifaz, Anita Buestán, Claudia Armas, Raquel Trujillo, Patricio Freire, Tamara León, Giselle Erazo, Liliana García, Marcela Alzate, Vicente Toapanta, Myriam Ortega, Daniela Caicedo, Alicia Pereira, Lenin Gómez-Barreno, Juan S. Izquierdo-Condoy, Merry Charlie, Esteban Ortiz-Prado, Katherine Simbaña-Rivera

“…Concerning sunscreen, 76.7% knew the reason for using it. The female group was 1.68 times more likely to get a higher score than the male group, and the groups between 61–70 and 71–80 years were 0.30 and 0.17 times less likely to get a higher score compared with the less than 20-years-old group, respectively. …”
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Collagen turnover biomarkers to predict outcome of patients with biliary cancer by Leonard Kaps, Muhammed A. Genc, Markus Moehler, Stephan Grabbe, Jörn M. Schattenberg, Detlef Schuppan, Rasmus Sund Pedersen, Morten A. Karsdal, Philipp Mildenberger, Annett Maderer, Nicholas Willumsen

“…Patients with high levels (cohort separated by median split) of PRO-C8 (HR 2.85, 95% CI 1.42; 5.73) followed by C3M (HR 2.33, 95% CI 1.2; 4.5), PRO-C3 (HR 3.09, 95% CI 1.5; 6.36) and CA 19–9 (HR 2.52, 95% CI 1.37; 4.64) as reference biomarker had a shorter OS. …”
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Concomitant exposure to benzodiazepines during pembrolizumab-based therapy for advanced non-small-cell lung cancer: a propensity-score matched analysis of monitoring agency data by Fabrizio Nelli, Enzo Maria Ruggeri, Antonella Virtuoso, Diana Giannarelli, Armando Raso, Federica Natoni, Gloria Pessina, Daniele Remotti, Mario Giovanni Chilelli, Carlo Signorelli, Agnese Fabbri

“…After a median follow-up of 16.3 [95% confidence interval (CI) 13.1–19.7] months, univariate analysis revealed no significant differences in terms of progression-free survival (PFS) or overall survival (OS) between BZD cohorts. …”
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The Use of Biopsy and “No-Biopsy” Approach for Diagnosing Paediatric Coeliac Disease in the Central European Region by Petra Riznik, Márta Balogh, Piroska Bódi, Luigina De Leo, Jasmina Dolinsek, Ildikó Guthy, Judit Gyimesi, Ágnes Horváth, Ildikó Kis, Martina Klemenak, Berthold Koletzko, Sibylle Koletzko, Ilma Rita Korponay-Szabó, Tomaz Krencnik, Tarcisio Not, Goran Palcevski, Éva Pollák, Daniele Sblattero, István Tokodi, Matej Vogrincic, Katharina Julia Werkstetter, Jernej Dolinsek

“…Data from 653 children (63.9% female, median age: 7 years, range: 7 months-18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. …”
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Detection of cervical precancerous lesions and cancer by small-scale RT-qPCR analysis of oppositely deregulated mRNAs pairs in cytological smears by Anastasia A. Artyukh, Mikhail K. Ivanov, Mikhail K. Ivanov, Sergei E. Titov, Sergei E. Titov, Victoria V. Dzyubenko, Sergey E. Krasilnikov, Sergey E. Krasilnikov, Anastasia O. Shumeikina, Anastasia O. Shumeikina, Anastasia O. Shumeikina, Nikita A. Afanasev, Anastasia V. Malek, Sergei A. Glushkov, Eduard F. Agletdinov

“…With this approach based on a five-mRNA combination (CDKN2A, MAL, TMPRSS4, CRNN, and ECM1), we generated a classifier having ROC AUC 0.935, diagnostic sensitivity 89.7%, and specificity 87.6% for ≥HSIL detection. …”
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Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study by Sudeshna Das, Yao Ge, Yuting Guo, Swati Rajwal, JaMor Hairston, Jeanne Powell, Drew Walker, Snigdha Peddireddy, Sahithi Lakamana, Selen Bozkurt, Matthew Reyna, Reza Sameni, Yunyu Xiao, Sangmi Kim, Rasheeta Chandler, Natalie Hernandez, Danielle Mowery, Rachel Wightman, Jennifer Love, Anthony Spadaro, Jeanmarie Perrone, Abeed Sarker

“…There was no statistically significant difference between GPT-4 and Nous-Hermes-2-7B-DPO for coverage (Mann-Whitney U=733.0; n1=37; n2=39; P=.89 two-tailed), coherence (U=670.0; n1=37; n2=39; P=.49 two-tailed), relevance (U=662.0; n1=37; n2=39; P=.15 two-tailed), length (U=672.0; n1=37; n2=39; P=.55 two-tailed), and hallucination (U=859.0; n1=37; n2=39; P=.01 two-tailed). …”
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Effect of Scalp-acupuncture Treatment on Language Reorganization in Poststroke Aphasia：A Functional Near-Infrared Spectroscopy by LIN Bingbing, NI Jinglei, XIONG Xiao, HUANG Yunshi, HUANG Jia

“…Conclusion Scalp acupuncture treatment combined with speech and language therapy can promote the recovery of language function in PSA patients，in which the improvement of verbal fluency may be related to the down-regulation of activation of the posterior part of the right middle temporal gyrus and the right pars triangularis gyri frontalis inferioris.…”
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Аналіз осередків скостеніння діафіза плечової кістки у плодів 20-32 тижні гестації by O.A. Koval, T.V. Khmara, I.I. Zamorskii, I.G. Biryuk, P.Ye. Kovalchuk

“…Під час аналізу проксимального поперечного діаметра діафіза правої плечової кістки отримали таке: у плодів віком 20-32 тижні цей показник зріс із 3,50±0,08 мм до 6,59±0,04 мм (для правої плечової кістки) та з 3,56±0,04 мм до 6,67±0,01 мм (для лівої плечової кістки). Поперечний діаметр середньої частини діафіза правої плечової кістки збільшився з 2,67±0,06 мм до 5,02±0,03 мм, а лівої плечової кістки - з 2,71±0,03 мм до 5,08±0,01 мм. …”
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Associations of Pretransplant Patient-Reported Outcomes Measurement Information System Physical Function Score With Kidney Transplant Outcomes by Junji Yamauchi, Amy M. Cizik, Katalin Fornadi, Dominik Thomas, Divya Raghavan, Duha Jweehan, Suayp Oygen, Silviana Marineci, Michelle Buff, Motaz Selim, Michael Zimmerman, Istvan Mucsi, Istvan Mucsi, Miklos Z. Molnar

“…However, a lower PROMIS-PF score was significantly associated with a higher risk of emergency room visits [adjusted odds ratios compared to normal: mild, 1.68 (95% confidence interval, 0.76–3.83); moderate/severe, 3.23 (1.34–7.79)] and rehospitalization [adjusted odds ratios: mild, 2.61 (1.16–5.90); moderate/severe, 2.53 (1.07–6.00)] within 1 month posttransplant. …”
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Large‐Vessel Occlusion Stroke Knowledge and Training for Stroke Severity Assessment Among Emergency Medical Services Personnel in the United States by Kaiz S. Asif, Robin Novakovic, Thanh N. Nguyen, Santiago Ortega‐Gutierrez, Youngran Kim, Amanda Jagolino‐Cole, Sushanth Aroor, Alicia Castonguay, Prateek Kumar, Ashutosh P. Jhadav, Dileep Yavagal, May Nour, Gabor Toth, Maxim Mokin, Sunil A. Sheth, Mouhammad A. Jumaa, Alhamza Al‐bayati, Mohamed Teleb, Ossama Y. Mansour, Shashvat M. Desai, Joshua Hartman, David S. Liebeskind, Ameer E. Hassan, Brijesh P. Mehta

“…Respondents who received training to perform an LVO scale demonstrated nearly twice the prevalence of LVO knowledge (30.6% versus 15.7%; prevalence ratio, 1.94 [95% CI, 1.50–2.53]) than respondents who did not receive training. …”
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