Safety, reactogenicity, and immunogenicity of Ad26.COV2.S co-administered with a quadrivalent standard-dose or high-dose seasonal influenza vaccine: a non-inferiority randomised controlled trialResearch in context by Gabriela Tapia-Calle, Gloria Aguilar, Nathalie Vaissiere, Carla Truyers, Pedro Ylisastigui, Erik Buntinx, Mathieu Le Gars, Frank Struyf, Gert Scheper, Macaya Douoguih, Javier Ruiz-Guiñazú, Robert Patrizi, Wai Ling, Sanne de Ridder, Marit de Groot, Maria Grazia Pau, Gerald Weidinger, Srividya Pradeep, Nadine Salisch, Sophie Cambre

Subjects: “…SARS-CoV-2…”
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MR体素内不相干运动成像对中晚孕期正常胎盘血流灌注的定量评价

“…单因素ANOVA方差分析结果显示不同孕龄组间f值(33. 81±2. 94), (29. 41±2. 70), (27. 71±1. 53) %的差异有统计学意义(P = 0. 000),D?D*值在3组间差异无统计学意义, 三组孕周的D值分别为:(1.28 ± 0.12) × 10-3, (1.32 ± 0.14) × 10-3, (1.27 ± 0.15) × 10-3 mm2/s(P = 0. 591); D*值分别为:(80.82 ± 9.86) × 10-3,(81.33 ± 12.55) × 10-3, (81.28 ± 10.30) × 10-3 mm2/s(P = 0.982)?…”
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血浆游离甲氧基肾上腺类物质对嗜铬细胞瘤和副神经节瘤的诊断价值 by 姚瑶, 冯绮玲, 李永洁, 张小云, 唐菊英, 郭颖, 张少玲, 严励

“…血浆MN如以0.395 nmol/L为切点，其灵敏性为60.2%，特异性为97.8%；NMN切点值为1.105 nmol/L，其诊断灵敏性为87.0%，特异性为98.7%，二者联合时灵敏性和特异性分别为91.7%、99.8%。…”
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Urinary biomarkers for diagnosing acute kidney injury in sepsis in the emergency department by Sumin Baek, Inwon Park, Seonghye Kim, Young Woo Um, Hee Eun Kim, Kyunghoon Lee, Jae Hyuk Lee, You Hwan Jo

“…NGAL (p = 0.014) and TIMP-2 × IGFBP-7 (p = 0.027) levels were different between the AKI and non-AKI groups. …”
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وراثت‏ پذیری و هتروزیس برخی صفات مرتبط با ارزش غذایی و کیفیت فیزیکی دانه برنج by راویه حیدری, نادعلی باقری, نادعلی بابائیان جلودار, حمید نجفی زرینی

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中老年人群代谢综合征和估算肾小球滤过率快速下降相关性研究 by 刘佩佳, 方佳, 李少敏, 汤磊乐, 刘迅

“…结果和非MetS人群相比，MetS人群校正混杂因素后，MetS与eGFR快速下降的发生无关（<italic>P</italic>&gt;0.05），MetS发生eGFR快速下降优势比（OR）为0.988，95%置信区间（CI）为0.811~1.204。在校正混杂因素后，MetS各组成成分eGFR快速下降的风险分别是：中心型肥胖OR 95%CI值为0.968（0.778， 1.204）， <italic>P</italic>=0.767；血糖升高OR 95%CI值为0.840（0.715， 0.986）， <italic>P</italic>=0.032；血压升高OR 95%CI值为1.087（0.919， 1.285）， <italic>P</italic>=0.328；高密度脂蛋白胆固醇降低OR 95%CI值为1.085（0.895， 1.316）， <italic>P</italic>=0.404；甘油三脂升高OR95%CI值为1.110（0.918， 1.343）， <italic>P</italic>=0.281。…”
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Development of Solid Self-Nanoemulsifying Drug Delivery System of Rhein to Improve Biopharmaceutical Performance: Physiochemical Characterization, and Pharmacokinetic Evaluation by More SM, Rashid MA, Kharwade RS, Taha M, Alhamhoom Y, Elhassan GO, Gangane P, Asar TO, Pise A, Kaleem M, Mujtaba MA

“…Further, the oral bioavailability study and brain tissue pharmacokinetics study were performed on Sprague-Dawley rats.Results: The optimized RL-SNEDDS had an average droplet size of 129.3 ± 1.57 nm, zeta potential of − 24.6 mV ± 0.34, % transmittance of 94.82 ± 0.61, and encapsulation efficiency of 98.86 ± 0.23. …”
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Towards a histological diagnosis of childhood small vessel CNS vasculitis by Maryam Nabavi Nouri, Anastasia Dropol, Pascal N. Tyrrell, Sheila Sheikh, Marinka Twilt, Jean Michaud, Benjamin Ellezam, Harvey B. Sarnat, Christopher Dunham, Peter W. Schutz, Julia Keith, David G. Munoz, Harry V. Vinters, Cynthia Hawkins, Susanne M. Benseler

Subjects: “…Sv-cPACNS…”
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Effect of peer support nursing on improvement of caregiver preparedness for care of low anal fistula in infants (同伴支持式护理提升婴儿低位肛瘘照顾者准备度的研究)... by GUO Yufan (郭雨凡), WANG Yanmei (王晏美), LI Jianan (李佳楠), LAI Lixia (来丽霞), WANG Yanzhi (王艳芝)

“…评价2组患儿照顾者准备度和焦虑指标。结果 观察组患儿照顾者的照顾者准备度量表(CPS)总分高于对照组患儿照顾者, 差异有统计学意义(P＜0. 01)。简易焦虑问卷评价结果显示, 观察组评分(2. 53±1. 07)分, 低于对照组的(5. 00±1. 08)分, 差异有统计学意义(P＜0. 01)。…”
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Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions by Vilde Øverlien Dåstøl, Vilde Øverlien Dåstøl, Kristine Løkås Haftorn, Hamid Khoshfekr Rudsari, Piotr Pawel Jaholkowski, Piotr Pawel Jaholkowski, Ketil Størdal, Ketil Størdal, Siri Eldevik Håberg, Siri Eldevik Håberg, Clarice R. Weinberg, Lisa G. Rider, Ole A. Andreassen, Ole A. Andreassen, Ole A. Andreassen, Anne Lise Brantsæter, Ida Henriette Caspersen, Ida Henriette Caspersen, Helga Sanner, Helga Sanner

“…A polygenic risk score (PRS) for JIA was used in a subsample to assess gene-environment interactions.ResultsWe identified 217 JIA patients and 71,884 controls. High vs low maternal intake of lean/semi-oily fish was associated with JIA (aOR 1.51, 95% CI 1.02-2.22), especially among boys (aOR 2.13, 95% CI 1.21-3.75). …”
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Preparation of oat galactolipid and anti-liver cancer effects of oat galactolipid–modified curcumin-loaded liver targeting vesicle by Huiying Ren, Nuo Chen, Yanqing Liu, Meimei Wu, Meimei Wu, Meimei Wu, Jingsong Yan, Jingsong Yan, Jingsong Yan, Mingxiang Chang, Mingxiang Chang, Mingxiang Chang, Hanmin Li, Hanmin Li, Hanmin Li

“…The hydrophilic–lipophilic balance, acid, ester, and saponification values of the oat galactolipids were 14.89, 47.22, 237.09, and 284.30, respectively. The morphology of the GCLTV was spherical, with an average particle size of 64.47 nm and average potential of −19.73 mV. …”
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Anti-Inflammatory Effects of Cerium Dioxide Nanoparticles on Peritonitis in Rats Induced by Staphylococcus epidermidis Infection by Yan Li, Hongmei Sun, Zhiqi Yin, Xuexi Guo, Jun Yan

“…Staphylococcus epidermidis solution was injected intraperitoneally with 107 CFU/ml of bacterial solution in the model group, while the control group was injected intraperitoneally with the same amount of normal saline, and the CeO2 and CeO2 + model groups were injected with 0.5 mg/kg CeO2 nanoparticles through the tail vein for 2 h and then injected with saline or bacterial solution for 2 h, respectively. …”
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SARS-CoV-2 infection and antibody seroprevalence in routine surveillance patients, healthcare workers and general population in Kita region, Mali: an observational study 2020–2021 by Ulla Ashorn, Per Ashorn, Nigel Klein, Samba O Sow, Camilla Ducker, Elaine Cloutman-Green, Dagmar Alber, Fadima Cheick Haidara, Juho Luoma, Laura Adubra, Henry Badji, Fatoumata Diallo, Rikhard Ihamuotila, Owen Martell, Uma U Onwuchekwa, Oumar Samaké, Awa Traore, Kevin Wilson, Yue-Mei Fan

“…For community serosurvey in December 2020, overall seroprevalence of SARS-CoV-2 antibodies was 27.7%. The highest age-stratified seroprevalence was observed in participants aged 60–69 years (45.5%, 95% CI: 32.3% to 58.6%). …”
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The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial by Sewar Khatib, Yuval Palgi, Yoni K Ashar, Natalya Polyvyannaya, Pavel Goldstein

“…Moreover, combined SS+TS resulted in an improvement in life satisfaction (B=–4.29, P<.0001) compared with SS (B=–2.38, P=.0042) and TS alone (B=–1.20, P=.13) groups (F2,39=3.47; P=.04). Finally, SS+TS demonstrated greater improvement in symptoms of general anxiety disorder (B=10.64, P<.0001) compared with SS (B=3.30 P=.01) and TS alone (B=1.13, P=.37) (F2,38=13.5; P<.001) groups. …”
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Combined induction by Cu(II) and veratrole enhances the degradation of high molecular weight polyaromatic hydrocarbons by Fusarium dlaminii ZH-H2 by Jiayuan Gao, Mingyue Qi, Xiaomin Wang, Xuan Feng, Jiahui Li, Guangwei Zhang, Shengdong Feng, Zhixin Yang, Guohui Ning

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Analytical methods for nanomaterials investigation in food and food-related materials by Daniele Passeri, Pierfrancesco Atanasio, Anacleto Proietti, Chiara Mancini, Flavio Cognigni, Giancarlo La Penna, Luca Buccini, Marco Rossi, Anna Chiara Turco, Marilena D'Amato, Angela Sorbo, Simone Dinarelli, Giulia D'Ettorre, Federica Aureli

“…Some important results are reported and their applications are discussed not only in the characterization of nanosized objects deliberately added to the food and food packaging to improve their properties, but also in the characterization of unwanted nano-sized and micro-sized objects that originate from possible environmental contamination that can happen at every step of the food chain starting from water. …”
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Tumor Deposits as an Adverse Prognostic Indicator in Stage III Colon Cancer: A Multicenter Database Study by Jeeyou Kim, MD, Dong Woon Lee, MD, Ji Won Park, MD, PhD, Seung-Bum Ryoo, MD, PhD, Heung-Kwon Oh, MD, PhD, Rumi Shin, MD, PhD, Jin Sun Choi, MD, Min Jung Kim, MD, Sung-Chan Park, MD, Duck-Woo Kim, MD, PhD, Seung Chul Heo, MD, PhD, Sung-Bum Kang, MD, PhD, Seung-Yong Jeong, MD, PhD, Kyu Joo Park, MD, PhD, Jae Hwan Oh, MD, PhD, On Behalf of the Seoul Colorectal Research Group (SECOG)

“…The survival outcomes of TD-positive patients without LNM were inferior to those of TD-negative patients with LN1–3 (5-year OS: 78.9 vs 87.8%, P = 0.04). The survival outcomes of TD-positive patients with LN1–3 were similar to those of TD-negative patients with LN ≥4 (5-year OS: 87.0 vs 77.1%, P = 0.11). …”
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Persistent organochlorine pesticides and cardiometabolic outcomes among middle-aged Latina women in a California agricultural community: The CHAMACOS Maternal Cognition Study by Marcella Warner, Stephen Rauch, Brenda Eskenazi, Lucia Calderon, Robert B. Gunier, Katherine Kogut, Nina Holland, Weihong Guo, Julianna Deardorff, Jacqueline M. Torres

“…In BHM models, a 10-fold increase in p,p′-dichlorodiphenyltrichloroethane (DDT) and β-hexacyclohexane (β-HCH) was positively associated with BMI (DDT: adj-β = 1.26, 95 % Credible Interval (CrI): 0.33, 2.20; β-HCH: adj-β = 1.56, 95 %CrI: 0.45, 2.67) and waist circumference (DDT: adj-β = 2.75, 95 %CrI: 0.65, 4.85; β-HCH: adj-β = 3.74, 95 %CrI: 1.24, 6.23). …”
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gp91phox, a Novel Biomarker Evaluating Oxidative Stress, Is Elevated in Subclinical Hypothyroidism by Xiaochun Ma, Furong Wang, Xiaowen Zhen, Lifang Zhao, Li Fang, Zhenfang Dong, Wenbin Chen, Xiaoming Zhou

“…The levels of serum soluble gp91phox evidently increased in the patients with SH with a high level of LDL-C (81.52 ± 37.00 ug/mL) as compared to the healthy controls (54.98 ± 1.83ug/mL, p<0.001), controls with high level of LDL-C (61.21 ± 4.48 ug/mL, p=0.038) and SH with a normal level of LDL-C (62.82 ± 11.67ug/mL, p=0.027). …”
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Independent and joint associations of neighbourhood greenness and walkability with transportational and recreational physical activity among youth and adults in Canada by Natalie Doan, Sebastian A. Srugo, Stephanie A. Prince, Rachel C. Colley, Daniel G. Rainham, Taru Manyanga, Gregory P. Butler, Richard Larouche, Sarah E. Turner, Justin J. Lang

“…Results: Among adults, but not youth, higher NDVI was independently associated with higher PATRA (β = 0.2, 95 % CI 0.02, 0.36) and PAREC (β = 0.3, 95 % CI 0.14, 0.47). …”
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