Designing a Model for Credit Risk Assessment of Customers for Guarantees Issued by the Export Guarantee Fund of Iran via Artificial Neural Network Model by Farshid Ahmadi Sartakhti, Kambiz Hojabr Kiani, Seyed Shamsoddin Hoseini, Abbas Memarnejad

“…Based on available statistics and official records within the Iranian entity, it can be observed that between the Iranian calendar years of 1387 and 1397, this fund issued guarantees totaling $6.7 billion, with the largest claim, exceeding $317 million, originating from the credit guarantees provided for the benefit of creditors. …”
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Association of different insulin resistance surrogates with all-cause and cardiovascular mortality among the population with cardiometabolic multimorbidity by Hongqiang Zhang, Zhixin Tu, Sihua Liu, Jumei Wang, Jie Shi, Xingyu Li, Rongdongqing Shi, Minghui Chen, Tong Yue, Sihui Luo, Yu Ding, Xueying Zheng

“…On the other hand, when the TyG index surpassed the inflection point, it demonstrated a positive correlation with cardiovascular mortality (HR 1.413; 95% CI = 1.075–1.857) and all-cause mortality (HR 1.279; 95% CI = 1.070–1.529). …”
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An interactive course program on nutrition for medical students: interdisciplinary development and mixed-methods evaluation by Gonza B. Ngoumou, Daniela A. Koppold, Laetitia Wenzel, Anne Schirmaier, Carolin Breinlinger, Lisa M. Pörtner, Stefan Jordan, Julia K. Schiele, Etienne Hanslian, Annika Koppold, Beate Stock-Schröer, Dimitra M. Varvarezou, Michael Jeitler, Miriam Ortiz, Andreas Michalsen, Wiebke Stritter, Georg Seifert, Christian S. Kessler

“…Various interactive didactic methodologies were used. 77.8% (n = 27) of the participants rated the course as very good or good. …”
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Three Weeks on a Ketogenic Diet Reduces Free Testosterone and Free Estradiol in Middle-Aged Obese Men and Women by Mads Svart, Nikolaj Rittig, Thien Vinh Luong, Nigopan Gopalasingam, Esben Thyssen Vestergaard, Lars Gormsen, Esben Søndergaard, Henrik Holm Thomsen, Claus H. Gravholt

“…Total testosterone was unaffected after the KD compared to the SDD in men (20.2 ± 1.23 nmol/l vs. 18.2 ± 1.23 nmol/l (p = 0.1)) and was lower after KD in women (0.87 ± 0.06 vs. 1.1 ± 0.06 nmol/l (p < 0.0001)). …”
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The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications by Ali Hendi Alghamdi, Aimun A.E. Ahmed, Mahadi bashir, Haidar abdalgadir, Asaad khalid, Ashraf N. Abdalla, Mohamed E. elzubier, Riyad almaimani, Bassem refaat, Khalid alzahrani, Saleh MS. alghamdi, Sheraz gul

“…Results: The six extracts showed variable IC50 values ranging from 1.77 to - 40.97 μg/mL. The most active extracts were C. rotundifolia coded as (stem; BEP-03A and leaves; BEP-03B) on HepG2 cells and showed ∼ 4 and 8 fold selectivity compared to normal MRC5 cells. …”
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Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research by Benjamin Punz, Maja Brajnik, Joh Dokler, Jaleesia D. Amos, Litty Johnson, Katie Reilly, Anastasios G. Papadiamantis, Amaia Green Etxabe, Lee Walker, Diego S. T. Martinez, Steffi Friedrichs, Klaus M. Weltring, Nazende Günday-Türeli, Claus Svendsen, Christine Ogilvie Hendren, Mark R. Wiesner, Martin Himly, Iseult Lynch, Thomas E. Exner

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Belimumab versus telitacicept in sequential treatment after rituximab for refractory lupus nephritis: a real-world multicentre study by Fei Han, Hong Pan, Yi Yang, Jianghua Chen, Jing Xue, Lan Lan, Yiting Chen, Pingping Ren, Yaomin Wang, Xin Lei, Jianhang Xu, Xiaochan Chen, Qiankun Zhang, Junni Wang, Nan Shi, Liangliang Chen, Lie Jin

“…After a follow-up duration of 26±12 months, renal objective remission rate was 80.0% (28 patients) in belimumab group and 85.7% (12 patients) in telitacicept group (difference, 5.7 percentage points, 95% CI, −25.8 to 26.8, p=1.000). …”
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Current Enzooticity of <i>Dirofilaria immitis</i> and <i>Angiostrongylus vasorum</i> in Central and Southern Italy by Donato Traversa, Simone Morelli, Angela Di Cesare, Chiara Astuti, Alessandra Barlaam, Mariasole Colombo, Fabrizia Veronesi, Barbara Paoletti, Raffaella Iorio, Raffaella Maggi, Alessandra Passarelli, Alessia Pede, Linda Rossi, Manuela Diaferia

“…Binomial logistic regression was performed to evaluate statistically significant associations between positivity for <i>D. immitis</i> and/or <i>A. vasorum</i> and potential risk factors. Overall, 35 (1.7%) and 62 (3.1%) dogs were positive for microfilariae of <i>D. immitis</i> and first stage larvae (L1) of <i>A. vasorum</i>, respectively, while 3 (0.1%) were co-infected by both nematodes. …”
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Biogeochemical cycling of sedimentary organic carbon and benthic nutrient fluxes in the semi-enclosed Jinhae Bay, Korea: insights into benthic-pelagic coupling by Sung-Uk An, Sung-Uk An, Kyung-Tae Kim, Sung-Han Kim, Sung-Han Kim, Ju-Wook Baek, Ju-Wook Baek, Hyun-Jeong Jeong, Hyun-Jeong Jeong, Chul-In Sun, Jin Young Choi, Jin Young Choi, Sokjin Hong, Dae In Lee, Jae Seong Lee, Jae Seong Lee

“…The burial flux into the sediment ranged from 3.96 ± 1.00 to 7.17 ± 1.64 mmol C m–2 d–1, and burial efficiencies were 4.25 to 15.8%, which indicated that deposited organic carbon was either mineralized in surface sediment before burial or laterally transferred by resuspension. …”
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Antioxidant, Physiochemical, and Sensory Properties of Functional Marshmallow Produced from Honey, Strawberry Concentrates, and Hibiscus Extract by Maher M. Al-Dabbas, Etaf G. Abu Samaan, Sehar Iqbal, Hani J. Hamad, Rawan Al-Jaloudi, Mohammad Shahein, Bha’a Aldin Al-Nawasrah, Abdalrahman Al-Zabt, Doa`a Al-Refaie, Nisreen Shehadeh, Mahmoud Abughoush

“…Among the formulations, F5 exhibited the highest phenolic and flavonoids contents (89.8 mg GAE/100 g and 1.62 mg RE/100 g, respectively) and reducing power activity (197.8% equivalent to 30 µg vitamin C). Additionally, F3 and F4 showed the strongest DPPH scavenging activity, with IC₅₀ values of 8.0 and 5.1 mg/mL, respectively. …”
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Value of triglyceride glucose-body mass index in predicting nonalcoholic fatty liver disease in individuals with type 2 diabetes mellitus by Xiaoyi Qian, Wenwen Wu, Boyang Chen, Simin Zhang, Chunmei Xiao, Long Chen, Jun Chen, Jun Chen, Lingli Ke, Meian He, Xiulou Li, Xiulou Li, Xiulou Li

“…The ROC curve was used to assess the predictive efficacy of the TyG-BMI index for NAFLD in T2DM patients.ResultsBMI predicted the development of NAFLD in T2DM patients with an area under the receiver operating characteristic (ROC) curve of 0.792 (95% CI 0.757-0.828), and the optimal cutoff value was 25.22, with 72.2% sensitivity and 71.6% specificity; The area under the receiver operating characteristic (ROC) curve of the TyG index to predict the development of NAFLD in patients with T2DM was 0.755 (95% CI 0.716-0.794), and the optimal cutoff value was 8. 945, with a sensitivity of 80.1% and a specificity of 59.2%; The area under the receiver operating characteristic (ROC) curve of TyG-BMI index to predict the development of NAFLD in T2DM patients was 0.852, (95% CI 0.822-0.882), and the optimal cutoff value was 227.385, with a sensitivity and specificity of 80.1% and 59.2%, respectively.ConclusionsThe TyG-BMI index is a significant predictor of comorbid NAFLD in T2DM patients and provides better screening performance than BMI alone. …”
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Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel-group, open-label study by David Cosgrave, Bairbre McNicholas, Ciara Hanley, John Robert Sheehan, Padraig Calpin, Maeve Kernan, Darragh Murphy, Alberto Alvarez‑Iglesias, John Ferguson, Camilla Giacomini, Christine Greene, Catriona Cody, Shane McGeary, Marion Murphy, Marianne Fitzgerald, Gerard Curley, Barry Dixon, Roger J. Smith, Claire Masterson, Daniel O’Toole, Frank van Haren, John G. Laffey

“…Abstract Background Nebulised unfractionated heparin may attenuate COVID-19 ARDS by reducing pulmonary microvascular thrombosis, blocking SARS-CoV-2 entry into cells, and decreasing lung inflammation. …”
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Universal capillary screening for chronic autoimmune, metabolic and cardiovascular diseases: feasibility and acceptability of the UNISCREEN study by Sara Angiulli, Aurora Merolla, Elisa Borgonovo, Rebecca De Lorenzo, Serena Spadoni, Barbara Fontana, Giuseppina Manganaro, Elena Rela, Alberto Bongiovanni, Rita Peracino, Chiara Bellino, Giulia Pata, Eleonora Bianconi, Sabina Martinenghi, Francesca Ulivi, Cristina Renzi, Cristina Renzi, Emanuele Bosi, Emanuele Bosi, UNISCREEN Study Group, Sara Angiulli, Aurora Merolla, Alberto Bongiovanni, Rebecca De Lorenzo, Elena Rela, Rita Peracino, Chiara Bellino, Giuseppina Manganaro, Elisa Borgonovo, Sara Critelli, Aldo Fici, Martina Mallus, Giulia Morocutti, Giulia Pata, Clara Soggetti, Chiara Calabrese, Alberico Di Resta, Maria Pia Ruggiero, Antonella Spano’, Francesca Biasco, Manuel Stocchi, Pietro Melodia, Giuseppe Ancona, Andrea Laurenzi

“…Before screening, 24.0% adults and 31.7% children’s parents were worried about the possibility of being diagnosed or identified as being at risk; worries decreased to 21.3 and 23.4%, respectively, after medical consultation. …”
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The Effect of Wheat Residues and Vermicompost on the Quality Characteristics of Corn (Zea mays L.) Forage and Soil Fertility by Hasanali Pooresmaeil, Mehdi Dahmradeh, Ahmad Ghanbari

“…The highest amount of organic carbon (0.212 %) and phosphorus (5.07 mg.lit-1) were achieved in the integrated system of 10% vermicompost + 90% wheat. …”
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Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort by Giehae Choi, Xiaoshuang Xun, Deborah H. Bennett, John D. Meeker, Rachel Morello-Frosch, Sheela Sathyanarayana, Susan L Schantz, Leonardo Trasande, Deborah Watkins, Edo D. Pellizzari, Wenlong Li, Kurunthachalam Kannan, Tracey J. Woodruff, Jessie P. Buckley

“…Higher melamine concentration was associated with longer gestational age (β^ per IQR increase of log2-transformed: 0.082 [95 % CI: −0.012, 0.177]; 2nd vs 1st tertile: 0.173 [-0.048, 0.394]; 3rd vs 1st tertile: 0.186 [-0.035, 0.407]). …”
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Development and external validation of a nomogram for the early prediction of acute kidney injury in septic patients: a multicenter retrospective clinical study by Qin-Yue Su, Wen-Jie Chen, Yan-Jun Zheng, Wen Shi, Fang-Chen Gong, Shun-Wei Huang, Zhi-tao Yang, Hong-Ping Qu, En-Qiang Mao, Rui-Lan Wang, Du-Ming Zhu, Gang Zhao, Wei Chen, Sheng Wang, Qian Wang, Chang-Qing Zhu, Gao Yuan, Er-Zhen Chen, Ying Chen

“…The AUC of the model in the development and validation cohorts was 0.914 (95% CI, 0.894–0.934) and 0.923 (95% CI, 0.895–0.952), respectively. …”
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Occurrence of Fungi on Duck Egg Shells and Drug Resistance Analysis of <i>Aspergillus</i> spp. Isolates by Andrzej Gaweł, Magdalena Siedlecka, Magdalena Karwańska, Milena Skrok, Iwona Przychodniak, Piotr Knap, Aleksandra Chmielina, Violetta Truszko, Maciej Kuczkowski, Karolina Bierowiec, Anna Woźniak-Biel, Barbara Szczepankiewicz, Kamila Bobrek

“…A total of 73.7% of the isolates were resistant to posaconazole and 68.4% to itraconazole. …”
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Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit by Maitee Rosende-Roca, Fernando García-Gutiérrez, Yahveth Cantero-Fortiz, Montserrat Alegret, Vanesa Pytel, Pilar Cañabate, Antonio González-Pérez, Itziar de Rojas, Liliana Vargas, Juan Pablo Tartari, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Mariola Moreno, Sílvia Preckler, Susanna Seguer, Miren Jone Gurruchaga, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Mercè Boada, Marta Marquié

“…However, we observed that women diagnosed with mild AD dementia progressed more rapidly based on their CDR score (HR = 2.57, 95%CI:2.33–2.84) than men (HR = 2.03, 95%CI: 1.71–2.41) (p-interaction = 0.01). …”
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Nonlinear water stress response functions can improve the performance of the DSSAT-CERES-Wheat model under water deficit conditions by Ning Yao, Yingnan Wei, Kunhao Jiang, Jian Liu, Yi Li, Hui Ran, Tehseen Javed, Hao Feng, Qiang Yu, Jianqiang He

“…Validation results using DSSAT v4.7 databases confirmed the enhanced performance of the modified model under water stress conditions. …”
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

“…Such ligands are broadly expressed by cancer cells of various origins and serve as targets for adoptive immunotherapy with effector cells endogenously expressing NKG2D or carrying an NKG2D-based chimeric antigen receptor (CAR). However, shedding or downregulation of NKG2D ligands (NKG2DL) can prevent NKG2D activation, resulting in escape of cancer cells from NKG2D-dependent immune surveillance.Methods To enable tumor-specific targeting of NKG2D-expressing effector cells independent of membrane-anchored NKG2DLs, we generated a homodimeric recombinant antibody which harbors an N-terminal single-chain fragment variable (scFv) antibody domain for binding to NKG2D, linked via a human IgG4 Fc region to a second C-terminal scFv antibody domain for recognition of the tumor-associated antigen ErbB2 (HER2). …”
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