Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer by Marjory Alana Marcello, Antonio Ramos Calixto, Jacqueline Fatima Martins de Almeida, Mariana Bonjiorno Martins, Lucas Leite Cunha, Camila Ayume Amano Cavalari, Elba C. S. Etchebehere, Ligia Vera Montalli da Assumpção, Bruno Geloneze, Andre Lopes Carvalho, Laura Sterian Ward

“…A multivariate logistic regression adjusted for gender, age, and BMI showed that the AG genotype of rs7799039 was an independent risk for DTC (OR, 11.689; P=0.0183; 95% CI, 1.516–90.119). Similarly, AG and GG genotypes of rs1137101 increased the susceptibility to DTC (OR, 3.747; P=0.027; 95% CI, 1.161–12.092 and OR, 5.437; P=0.013; 95% CI, 1.426–20.729). …”
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Call to Action: Lead Pharmacy into the Next Decade by Gregory Zumach, Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Anthony Olson, Andrew Bartlett, Nilushi Karunaratne, Betty Exintaris

“…Academic Medicine 84(6):p 814, June 2009. • Peeters MJ, Harpe SE. “Last Matter: Introducing infographics to Methodology Matters.” …”
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Emerging malaria in Indonesia: An overview of Plasmodium knowlesi infections by Nisa Fauziah, Karomahul Malaya Jati, Fedri Ruluwedrata Rinawan, Naufal Fakhri Nugraha, Bachti Alisjahbana, Jontari Hutagalung

“…Individuals working outdoors were not significantly more protected compared to those working indoors (p-value of 0.116, OR = 0.15, 95 % CI: 0.02–1.49). The origin of the sample was found to be the most significant factor (p-value <0.001), with individuals from Kalimantan having the highest risk for malaria caused by P. knowlesi (OR = 3.97, 95 % CI: 2.10–7.49). …”
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The Use of L-Menthol in Endoscopic Transpapillary Interventions. Prospective Randomized Dual-Center Study by M. A. Anishchenko, M. A. Nazmeev, S. G. Shapovalyants, S. A. Budzinsky, A. V. Rogov, R. R. Zaynutdinov, A. S. Melnikova, E. D. Fedorov, E. N. Platonova

“…The study included 126 patients, 69 (54.8 %) men and 57 (45.2 %) women, mean age — 62.1 ± 1.8 years. …”
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环孢素影响化疗药物对视网膜母细胞瘤细胞的抑制作用 by 毛羽翔

“…足叶乙甙+1.0 mg/L CSA组(G6),每组各加样5孔?G7组为不同浓度CSA单独作用于Rb细胞?用从0.004至1.00 mg/L倍数增加的9个不同浓度含量化疗药物卡铂和足叶乙甙及加入0.5 mg/L和1.0 mg/L浓度的环孢素作用于体外培养的SO-Rb50细胞?…”
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HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique by Nalia Ismael, Cidia Hussein, Cacildo Magul, Humberto Inguane, Aleny Couto, Amancio Nhangave, Ana Muteerwa, Mahoudo Bonou, Artur Ramos, Peter Wesley Young, Sonia Chilundo, Rhoderick Machekano, Lauren Greenberg, Juliana da Silva, Nilesh Bhatt

“…After three adherence counseling sessions, participants with VF underwent genotyping for drug resistance mutations (DRMs) using the Stanford HIVdb Program. Of 717 participants (median age 39.2 years, 70.7% female), 217 (30.2%) had VF, 193 (88.9%) underwent genotyping, with 183 (94.8%) successfully genotyped. …”
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Acute effects of a dog sport on fitness parameters in young adults: a randomised controlled crossover study by Valerio Giustino, Ignazio Leale, Luca Cicero, Luca Petrigna, Monica Lo Nigro, Veronica Fontana, Elena Mignosi, Pietro Cataldo, Antonio Macaluso, Manuel Gómez-López, Giovanni Cassata, Giuseppe Battaglia

“…Moreover, the subjective level of perceived exertion during exercise was assessed using the Borg category-ratio scale (Borg CR-10). Results Results showed significant differences in the number of steps ( p = 0.011), walking time ( p = 0.006), average heart rate (HR) ( p = 0.004), maximum HR ( p = 0.003), and perceived exertion ( p = 0.007) between the two conditions at T 1 . …”
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基于TGF-β1/smads 信号通路研究电针对少弱精症大鼠的影响 by 孟纯雪, 王菲, 孙文静, 杨楠, 赵海龙, 张生富, 马惠昇, 郭斌

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Clinical Study of Repetitive Transcranial Magnetic Stimulation Combined with Social Rehabilitation Training on Children with Attention Deficit Hyperactivity Disorder by JING Xinli, ZHU Min, NIU Yujia

“…The social activity score in WFIRS-P was positively correlated with opposition and defiance score in SNAP-Ⅳ (<italic>r</italic>=0.293, <italic>P</italic>=0.023), as well as the DSRSC score (<italic>r</italic>=0.347, <italic>P</italic>=0.007).ConclusionrTMS combined with social rehabilitation training can effectively improve attention deficit hyperactivity disorder, anxiety and depression of children with ADHD, and enhance their family and social activity functions.…”
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Measurement of Corneal Biomechanical Properties using Corneal Visualisation Scheimpflug Technology and Ocular Response Analyser in Healthy Saudi Female Adults: A Cross-sectional St... by Farah Maqsood, Noura Aldossari, Menwah Al Matrafi, Musarat Amina, Maram M Bawazir

“…Results: The mean age of the participants was 20.74±1.89 years, mean Spherical Equivalent (SE) refraction was -1.41±1.97 Diopters (D), the mean IOP was 16.82±1.96 mmHg, and the mean CCT was 569.43±27.22 μm for the right eyes. …”
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Factors influencing changes in the quality of life of the Hainan migratory population with hypertension: a survey of the Chengmai mangrove bay community by Qiaochun Chen, Jing Zhou, Na Li, Luming Liu, Yixuan Li, Wenfang Long, Ziyue Luo, Yunru Liu, Sha Xiao

“…The factors that influenced the improvement in the subjects’ QoL in Hainan included hypertension classification (OR = 2.336, 95% CI: 1.125 ∼ 4.853, P = 0.023) and BMI (OR = 6.402, 95% CI: 1.009 ∼ 40.624, P = 0.049). …”
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Early changes of peripheral circulating immune subsets induced by PD-1 inhibitors in patients with advanced malignant melanoma and non-small cell lung cancer by Simona Borilova, Peter Grell, Iveta Selingerova, Lenka Gescheidtova, Marie Mlnarikova, Ondrej Bilek, Radek Lakomy, Alexandr Poprach, Jan Podhorec, Igor Kiss, Rostislav Vyzula, Barbora Vavrusakova, Jiri Nevrlka, Lenka Zdrazilova-Dubska

“…Furthermore, we also evaluated the predictive value of CD28 and ICOS/CD278 co-expression on T cells. Results Patients who achieved disease control on ICIs had a significantly lower baseline proportion of CD4 + TEM (p = 0.013) and tended to have a higher baseline proportion of CD4 + TCM (p = 0.059). …”
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Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling by Xinghua Yu, Rui Yao, Ge Meng, Lingan Zeng, Leyi Zhou, Yingkang Shen, Amali Upekshika Wijayaraja, Reshmi Hareendra Kariyapperuma, Wentao Xu, Yuxiang Mei, Xinyan Gu, Wen-Long Lei, Pengfei Zhang, Fei Sun

Subjects: “…Plastic cups…”
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Nomogram to predict 3 month prognosis of acute ischemic stroke among young adults by Qian He, Qian He, Miaoran Wang, Haoyue Zhu, Ying Xiao, Rui Wen, Xiaoqing Liu, Yangdi Shi, Linzhi Zhang, Bing Xu

“…Gender (male vs. female; Odds ratio[OR], 0.5562[95% Confidence Interval (CI), 0.3104–1.0478]; p = 0.053), family history of stroke (OR, 3.5698[95%CI 1.5632–8.0329], p &lt; 0.001), prior stroke (OR, 2.1509[95%CI 1.2610–3.6577], p &lt; 0.001), previous heart disease (OR, 3.4047[95%CI, 1.7838–6.6976], p &lt; 0.01) toast type (cardio-embolism stroke vs. large-artery atherosclerosis (LAA), OR, 0.0847[0.0043–0.5284], p &lt; 0.01), toast type (stroke of undetermined etiology vs. …”
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Incidence, long-term predictors and progression of chronic kidney disease among African migrants and non-migrants: the transcontinental population-based prospective RODAM cohort st... by Charles Agyemang, Ellis Owusu-Dabo, Erik Beune, Karlijn Meeks, Bert-Jan H van den Born, Liffert Vogt, Felix P Chilunga, Charles F Hayfron-Benjamin, Sampson Twumasi-Ankrah, Muhulo Muhau Mungamba, Eva L van der Linden, Engwa A Godwill, Samuel N Darko, Benedicta N Chungag

“…Overall age- and sex standardised CKD incidence was 11.0% (95% CI 9.3% to 12.3%) in the population, with Ghanaians residing in Amsterdam at (7.6%; 5.7% to 9.5%) and Ghanaians residing in Ghana at (12.9%; 10.9% to 14.9%). …”
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Influencing factors of the participation of patients with severe mental disorders in community health service management by Shiming Li, Yingying Ji, Queping Yang, Ying Jiang, Qitao Yin, Haohao Zhu

“…Multivariate logistic regression analysis revealed the following negative factors influencing participation in community health service management: Age group 31–40 years (OR = 0.532, 95% CI: 0.434–0.653), Age group 41–50 years (OR = 0.557, 95% CI: 0.468–0.663), Age group 51–60 years (OR = 0.746, 95% CI: 0.635–0.877), Age group &gt;60 years (OR = 0.840, 95% CI: 0.719–0.969), Duration of illness 6–10 years (OR = 0.376, 95% CI: 0.307–0.461), Duration of illness 11–15 years (OR = 0.312, 95% CI: 0.249–0.390), Duration of illness 16–20 years (OR = 0.702, 95% CI: 0.529–0.932), Duration of illness &gt;20 years (OR = 0.701, 95% CI: 0.514–0.957), Education level of college or above (OR = 0.719, 95% CI: 0.560–0.923), Current student status (OR = 0.565, 95% CI: 0.419–0.760), Absence of social welfare benefits (OR = 0.643, 95% CI: 0.572–0.723), History of violent or harmful behavior (OR = 0.553, 95% CI: 0.442–0.692), Non-participation in community rehabilitation activities (OR = 0.170, 95% CI: 0.101–0.284). …”
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Risk Factors for Intrauterine Device Malposition by Ann C. Frisse, Jay B. Louik, Isha A. Kachwala, Haotian Wu, Nicole Felix, Thammatat Vorawandthanachai, Karina Avila, Nerys C. Benfield

“…Radiologists, compared to gynecologists, were more likely to describe an IUD as malpositioned (RR = 1.53, 95% CI: 1.21, 1.99). Abnormal uterine bleeding (AUB) as an indication for the ultrasound and fibroids visualized on ultrasound were more common in the malposition group compared to the non-malpositioned group (19.7% compared to 14.9%, p = 0.02 and 21.6% compared to 15.9%, p < 0.01 respectively). …”
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Value of routine blood count surveillance in detecting relapse in acute lymphoblastic leukemia by Sarah AlHarbi, Sarah AlHarbi, Areej Taha, Areej Taha, Ahmed Ashi, Ahmed Ashi, Naglla Elimam, Naglla Elimam, Sami Althubaiti, Sami Althubaiti, Sami Althubaiti

“…The sensitivity and specificity of neutropenia, leukopenia, thrombocytopenia, anemia, and pancytopenia were 11.11% and 47.9%, 0% and 50%, 33.3% and 98.31%, 0% and 99.4%, and 33.3% and 96.07%, respectively. …”
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Addressing inhaler technique challenges in cognitively impaired chronic obstructive pulmonary disease patients: the impact of customized training programs by Vaishnavi V Gaonkar, Vinay V Shanbhag, Shreya S Kajave, Mahek R Mattikop, Mandati Santhosh Reddy

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Evolution paths of urban forms influenced by landforms: Asynchrony but convergence by Chao Yang, Qiyan Huang, Qiong Xian, Meng Yuan, Xiaoming Cong, Lisha Xun, Jianxiong Cheng, Hongyi Pan

“…Over the past 30 years, Sichuan’s overall similarity index rose from 0.07 to 0.18, revealing a trend towards convergent urban form evolution. …”
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