New Option for Antibiotic Susceptibility Testing in Clinical Practice: Performance Evaluation of AutoMic-i600 Automatic System Based on Broth Microdilution Method by Lin C, Zhang H, Wu Q, Qiu X, Li Q, Wu G

“…Importantly, for drug-resistant bacteria, AutoMic-i600 demonstrated a higher overall agreement than Vitek 2 (EA: 98.1% vs 94.8%, CA: 97.5% vs 92.0%), especially in Gram-negative bacteria (EA: 97.7% vs 93.5%, CA: 97.7% vs 89.3%). …”
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Multimodal Imaging of Patients With Gliomas Confirms C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy by Kai R. Laukamp MD, Florian Lindemann PhD, Matthias Weckesser MD, Volker Hesselmann MD, Sandra Ligges PhD, Johannes Wölfer MD, Astrid Jeibmann MD, Bastian Zinnhardt PhD, Thomas Viel PhD, Michael Schäfers MD, Werner Paulus MD, Walter Stummer MD, Otmar Schober PhD, MD, Andreas H. Jacobs MD

“…FLAIR/T2-MRI visualized greatest tumor extent with differences to MET-PET being greater in posttherapy (64.6 ± 62.7 cm 3 ) than in newly diagnosed patients (20.5 ± 52.6 cm 3 ). …”
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Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting by Abel Tenaw Tasamma, Tsegab Alemayehu Bukate, Abdulrahim Mehadi, Bereket Tagesse Handiso, Beniam Yohannes Kassa, Eman Omer Hassen, Zekarias Seifu Ayalew, Dawit Habtie Tegegne, Gebeyehu Tessema Azibte, Tigest Abebaw Zewdie, Tinsaye Zergaw Shihur, Yonas Degelo Geremamo, Yeabsira Dessalegne Mesfin, Rediet M. Alemayehu, Amanuel Kassu Asefa, Fozia Abdela, Addisu Melkie

“…The most common type of thrombosis was deep vein thrombosis (DVT) (77.1%). The primary composite outcome of VTE recurrence, major bleeding event, and all‐cause mortality occurred in 25 (24.3%) patients in the warfarin group and 11 (11.2%) in the rivaroxaban group (hazard ratio (HR), 0.48; 95% confidence interval (CI), 0.24–0.97; p = 0.041). …”
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Distinct Neutralising and Complement-Fixing Antibody Responses Can Be Induced to the Same Antigen in Haemodialysis Patients After Immunisation with Different Vaccine Platforms by Nadezhda Wall, Rachel Lamerton, Fiona Ashford, Marisol Perez-Toledo, Aleksandra Jasiulewicz, Gemma D. Banham, Maddy L. Newby, Sian E. Faustini, Alex G. Richter, Haresh Selvaskandan, Roseanne E. Billany, Sherna F. Adenwalla, Ian R. Henderson, Max Crispin, Matthew Graham-Brown, Lorraine Harper, Adam F. Cunningham

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Preparation, Reliability, and Validity of a Japanese Version of the “Satisfaction of Treatment among Caregivers of Dependent Type 2 Diabetic Patients” Questionnaire by Satoshi Ida, Ryutaro Kaneko, Kanako Imataka, Kaoru Okubo, Yoshitaka Shirakura, Kentaro Azuma, Ryoko Fujiwara, Hiroka Takahashi, Kazuya Murata

“…Factor analyses showed a single-factor structure both with and without rotation. The STCD2-J scores were significantly inversely correlated with HbA1c (r=−0.27, P<0.001). …”
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纯氧与空气复苏对缺氧新生大鼠肝细胞凋亡 及Bcl-2和Bax 蛋白表达的影响

“…【目的】 为了比较纯氧与空气复苏对缺氧新生大鼠的复苏效果,探讨新生大鼠肝细胞凋亡及Bcl-265380;Bax蛋白表达在缺氧复苏中的作用65377; 【方法】 采用SD新生大鼠建立缺氧模型,并分组进行纯氧与空气复苏65377;实验分为正常对照组(无预缺氧和复氧实验)65380;纯氧复苏组(PO组) 和空气复苏组(RA组) 65377;取肝组织,HE 染色光镜观察肝组织病理变化,TUNEL法测定肝细胞凋亡指数,免疫组化检测肝组织Bcl-265380;Bax蛋白的表达情况65377;【结果】 与正常对照组相比,PO组可见肝细胞肿胀,肝细胞有部分细胞器缺失,肝细胞呈明显的片状坏死,有炎性细胞浸润,肝细胞索排列紊乱65377;RA组肝细胞索排列基本正常, 肝细胞损伤程度,炎细胞浸润及肝细胞肿胀都较PO组轻65377;PO 24 h及72 h亚组的细胞凋亡指数分别为(11.2 ± 3.2)%和(9.2 ± 1.0)%,RA 24 h及72 h亚组的细胞凋亡指数分别为(9.0 ± 2.9)%和(7.4 ± 1.9)%,均低于相应的PO各亚组(P < 0.01)65377;PO 24 h及72 h亚组Bcl-2蛋白表达(11.55 ± 1.06)%和(10.49 ± 1.03)%, 均低于对应的RA各亚组,RA 24 h及72 h亚组Bcl-2蛋白表达分别为(13.06 ± 2.35)%和(11.71 ± 1.69)%65377;PO 24 h及72 h亚组Bax蛋白表达分别为(4.81 ± 1.13)%和(4.62 ± 0.79)%,均高于对应的RA各亚组,RA 24 h及72 h亚组Bax蛋白表达分别为(4.08 ± 0.31)%和(3.88 ± 0.48)%65377;PO组与RA组的细胞凋亡指数65380;Bcl-2及Bax蛋白表达及Bcl-2/Bax比值差异具有统计学意义(P < 0.01), 各组内亚组之间差异无统计学意义(P > 0.05)65377; 【结论】 纯氧复苏较空气复苏后新生大鼠肝细胞的凋亡更严重65377;纯氧复苏促进Bax基因的表达上调,空气复苏可使凋亡抑制基因Bcl-2表达上调,暗示纯氧复苏对新生大鼠肝的损伤要重于空气复苏65377;…”
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Corticostriatal glutamate‐mediated dynamic therapeutic efficacy of electroacupuncture in a parkinsonian rat model by Xinxin Jiang, Min Sun, Yitong Yan, Yanhua Wang, Xinyu Fan, Jing Wei, Ke Wang, Peirong Liang, Zirui Wang, Jihan Wang, Xiaomin Wang, Jun Jia

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Association of Serum Alpha-Tocopherol and Retinol with the Extent of Coronary Lesions in Coronary Artery Disease by Carolinne Thaísa de Oliveira Fernandes Miranda, Victor Hugo Rezende Duarte, Marina Sampaio de Menezes Cruz, Mychelle Kytchia Rodrigues Nunes Duarte, Jéssica Nayara Góes de Araújo, Ayda Maria Quirino Silva dos Santos, Juliana Marinho de Oliveira, Maria Sanali Moura Oliveira Paiva, Adriana Augusto Rezende, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, Karla Danielly da Silva Ribeiro, André Ducati Luchessi, Vivian Nogueira Silbiger

“…Patients with coronary artery disease (n=177) aged 30–74 years, who underwent their first coronary angiography, were enrolled. …”
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Evaluation of pulmonary tuberculosis disease burden in Shenyang, China, 2023 by Huijie Chen, Haiyan Bi, Peng Li, Zhixing Yang, Lihai Wen, Baijun Sun, Wei Sun

“…The highest incidence was 107.00/105 in the group of the population aged 80 and above (X 2 = 1171.75, p<0.001). …”
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Effectiveness of a Web-Based Medication Education Course on Pregnant Women’s Medication Information Literacy and Decision Self-Efficacy: Randomized Controlled Trial by Suya Li, Hui-Jun Chen, Jie Zhou, Yi-Bei Zhouchen, Rong Wang, Jinyi Guo, Sharon R Redding, Yan-Qiong Ouyang

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR2100041817; https://www.chictr.org.cn/showproj.html?…”
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<i>Ehrlichia</i> Species in Dromedary Camels (<i>Camelus dromedarius</i>) and Ruminants from Somalia by Aamir M. Osman, Ahmed A. Hassan-Kadle, Marcos R. André, Flávia C. M. Collere, Amir Salvador Alabí Córdova, Fabiano Montiani-Ferreira, Thállitha S. W. J. Vieira, Abdalla M. Ibrahim, Abdulkarim A. Yusuf, Rosangela Z. Machado, Rafael F. C. Vieira

“…<i>E. ruminantium</i> was detected in 13.7% (18/131) of cattle by <i>pCS20</i>-PCR, but none were positive for the <i>map1</i> gene. …”
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The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review by Perez, Grégoire, Bournez, Laure, Boulanger, Nathalie, Fite, Johanna, Livoreil, Barbara, McCoy, Karen D., Quillery, Elsa, René-Martellet, Magalie, Bonnet, Sarah I.

“…Prevalence data of detected pathogens are summarised in different maps. Results from 187 identified references show that the species is present in most departments, but scarce under Mediterranean climates and in coastal habitats. …”
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Magnetic hybrid chitin-horse manure humic acid for optimized Cd(II) and Pb(II) adsorption from aquatic environment by Rahmat Basuki, Yusuf Bramastya Apriliyanto, Elva Stiawan, Adya Rizky Pradipta, Bambang Rusdiarso, Budi Riza Putra

“…Hybrid magnetic-humic acid-chitin (HMHA-Ch-Fe3O4) was successfully prepared from horse manure and crab shell waste as economical and green adsorbent for Cd(II) and Pb(II). …”
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Construction of a diagnostic model for chronic mountain sickness among young male migrants to high-altitude areas by ZHANG Quan, CHEN Jian, LIU Bao

“…Further analysis revealed that creatine kinase-MB/creatine kinase （CK-MB/CK， OR=2.17， 95%CI： 1.43~3.28）， high-altitude residence time （OR=2.44， 95%CI： 1.08~5.54）， and body mass index （BMI， OR=1.62， 95%CI： 1.05~2.50） were 3 major independent risk factors for CMS. …”
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Survey Report Analysis on Parasitic and Microbial Quality of Laboratory Animals in Sichuan Province, 2017-2023 by LIU Lida, CHEN Bing, XIE Na, LIU Li, ZHUANG Siqi, ZOU Yixing

“…In 2019, Staphylococcus aureus and Klebsiella pneumoniae were detected, with a pass rate of 86.7%. In 2021, Sendai virus antibodies were detected, yielding a pass rate of 85.7%.The pass rate in 2020, 2022, and 2023 was 100%. …”
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Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D by Hugo Fabre, Maxime Ducret, Olivier Degoul, Jonathan Rodriguez, Emeline Perrier-Groult, Elisabeth Aubert-Foucher, Marielle Pasdeloup, Céline Auxenfans, Colin McGuckin, Nico Forraz, Frédéric Mallein-Gerin

“…BM-, WJ-, DP-, and AT-MSCs did not differ in terms of viability, clonogenicity, and proliferation. …”
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Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden. by Qingyun Yao, Jiangrong Wang, K Miriam Elfström, Björn Strander, Joakim Dillner, Karin Sundström

“…Moreover, primary HPV testing had a higher sensitivity for detecting CIN2+ within a 7-year interval than primary cytology testing within a 5-year interval (89.6% versus 50.9%, p < 0.0001). …”
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Efficacy and Safety of a Novel Tapered-Tip Sheath System for Biliary-Lesion Tissue Sampling: A Randomized Controlled Trial by Hirokazu Okada, Norimitsu Uza, Tomoaki Matsumori, Hajime Yamazaki, Muneji Yasuda, Takeshi Kuwada, Yoshihiro Nishikawa, Takahisa Maruno, Masahiro Shiokawa, Atsushi Takai, Ken Takahashi, Akihisa Fukuda, Etsuro Hatano, Sachiko Minamiguchi, Hiroshi Seno

“…Adverse events occurred in 4.0% (1/25) and 36.0% (9/25) of patients in the new and conventional method groups, respectively (risk ratio, 0.11; 95% CI, 0.02 to 0.81; risk difference, -32.0%; 95% CI, -52.3% to -11.7%; p=0.005). …”
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Circulation of <i>Mycobacterium tuberculosis</i> strains of the Beijing Central Asian Outbreak genotype in the Kemerovo region — Kuzbass in 2018–2022 by Svetlana N. Zhdanova, Anna A. Vyazovaya, Irina B. Lebedeva, Vyacheslav V. Sinkov, Ilya G. Kondratov, Yakov Sh. Schwartz, Lyubov V. Rychkova, Elena B. Brusina, Igor V. Mokrousov, Oleg B. Ogarkov

“…A high level of MDR and pre-XDR was detected in Beijing genotype strains in the M. tuberculosis population of the Kemerovo region — Kuzbass, especially the B0/W148 (97.2%) and CAO (87.5%) subtypes. Beijing CAO strains, detected mainly in newly diagnosed HIV/TB patients, require further monitoring and control of their spreading.…”
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Combined application of chemical and organic fertilizers enhances soil organic carbon sequestration and crop productivity by improving carbon stability and management index in a ri... by Hu Xu, Adnan Mustafa, Qudsia Saeed, Guiying Jiang, Nan Sun, Kailou Liu, Jiri Kucerik, Xueyun Yang, Minggang Xu

“…Conversely, it showed the lowest OC values in the labile fraction and active pool compared to CK, NPK, and 2NPK treatments. Additionally, NPKM significantly (P < 0.05) increased CMI (by 47 and 33%) over CK and NPK treatments, which suggests that soil receiving NPKM was better managed. …”
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