A Peculiar ICME Event in August 2018 Observed With the Global Muon Detector Network by W. Kihara, K. Munakata, C. Kato, R. Kataoka, A. Kadokura, S. Miyake, M. Kozai, T. Kuwabara, M. Tokumaru, R. R. S. Mendonça, E. Echer, A. Dal Lago, M. Rockenbach, N. J. Schuch, J. V. Bageston, C. R. Braga, H. K. Al Jassar, M. M. Sharma, M. L. Duldig, J. E. Humble, P. Evenson, I. Sabbah, J. Kóta

“…The cosmic‐ray density increase can be interpreted in terms of the adiabatic heating of cosmic rays near the trailing edge of the flux rope, as the corotating interaction region prevents free expansion of the flux rope and results in the compression near the trailing edge. …”
Get full text

DETERMINATION OF TECHNOPARK ACTIVITY BY REGULATORY AND LEGISLATIVE ACTS by Nikolay S. Novikov, Irina V. Karpova

Get full text

Effect of rapamycin-eluting stents on in-stent restenosis and early inflammatory response in coronary artery narrowing animal models by Jianbing Zhang, Jingyi Zhu, Baiping Sui, Ying Wang, Bingxue Zhang

“…The neointimal area in the S2 and S3 groups was significantly smaller than that in the S1 and D0 groups (S1 group: 3.44 ± 0.84, S2 group: 1.78 ± 0.25, S3 group: 2.07 ± 0.41, D0 group: 3.43 ± 0.72, P < 0.05). The degree of lumen narrowing in the S2 and S3 groups was significantly lower than that in the S1 and D0 groups (S1 group: 44.25 ± 3.66%, S2 group: 14.19 ± 2.01%, S3 group: 15.29 ± 2.45%, D0 group: 21.79 ± 3.51%, P < 0.05). …”
Get full text

Arthralgia and Extraintestinal Manifestations in Crohn’s Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis by Ivan Giovannini, Nicola Cabas, Marco Marino, Annarita Tullio, Ilaria Tinazzi, Angela Variola, Carmelo Cicciò, Fabro Cinzia, Berretti Debora, Chiara Zuiani, Rossano Girometti, Luca Quartuccio, Alen Zabotti, Lorenzo Cereser

“…Sacroiliitis detected on MRE was not associated with an increased risk of IBD-related arthritis (odds ratio [OR] = 2.12 [95% confidence interval (CI) 0.36, 12.53, p = 0.408]). In contrast, the presence of arthralgia and EIMs were found to be a predictor for IBD-related arthritis development (OR = 84.0 [95% CI 8.18, 862.39, p < 0.0001] and OR = 7.37 [95% CI 1.25, 43.32, p = 0.027], respectively). …”
Get full text

Effects of <i>Lactiplantibacillus plantarum</i> on Metabolites and Flavors in Synthetic Microbiota During Baijiu Fermentation by Chunyue Yan, Xurui Chen, Quan Liu, Tengyu Xu, Qian Zhang, Xueli Jin, Bei Liao, Xiong Chen, Xin Li

“…Notably, among the three different chassis microbial fermentation protocols involving <i>L. plantarum</i>, the protocol with the highest microbial diversity exhibited a greater capacity to produce lactic acid (1.56 ± 0.19 mg/g), ethanol (5.74 ± 0.47 mg/g), and reducing sugars (6.39 ± 0.31 mg/g). …”
Get full text

经尿道钬激光开窗治疗儿童重复肾合并输尿管囊肿 by 张殷, 潮敏, 沈剑, 蒋加斌, 张晔, 方向, 张开平, 张贤生

“…其中1例因再植术后输尿管末端梗阻经历了再次的输尿管再植手术，另3例为上半肾切除术后输尿管残端综合征进行了输尿管膀胱再植手术。A、B两组相比，平均手术时间（31.77±13.43）min <italic>vs. </italic>（174.46±37.79） min，<italic>t</italic>=-13.131，<italic>P</italic>=0.000，和术后住院天数（2.27±1.93）d <italic>vs. …”
Get full text

Future climate or land use? Attribution of changes in surface runoff in a typical Sahelian landscape by Yonaba, Roland, Mounirou, Lawani Adjadi, Tazen, Fowé, Koïta, Mahamadou, Biaou, Angelbert Chabi, Zouré, Cheick Oumar, Queloz, Pierre, Karambiri, Harouna, Yacouba, Hamma

“…An increase in rainfall (13.7% to 18.8%) is projected, which is the major contributor to the increase in surface runoff (24.2% to 34.3%). …”
Get full text

Targeting the NOTCH2/ADAM10/TCF7L2 Axis‐Mediated Transcriptional Regulation of Wnt Pathway Suppresses Tumor Growth and Enhances Chemosensitivity in Colorectal Cancer by Zhen Xiang, Yiwei Wang, Xiao Ma, Shuzheng Song, Yuanqiao He, Jiamin Zhou, Longhai Feng, Su Yang, Yibin Wu, Bingran Yu, Guangkai Xia, Weiqi Xu, Yiming Zhao, Lu Wang

Subjects: Get full text

长链非编码RNA HULC对胶质母细胞瘤原位移植瘤模型肿瘤生长的促进作用 by 胡宇辰, 尹恬恬, 李倩, 叶珊, 吴景

“…细胞凋亡实验显示VEC组和HULC-over组早期凋亡率分别为（3.55±0.56）%和（0.09±0.01）%；NC组和HULC-siRNA组早期凋亡率分别为（2.89±0.67）%和（7.13±0.14）%，过表达HULC细胞早期凋亡率降低，沉默表达HULC细胞早期凋亡率升高（P＜0.01）。…”
Get full text

Reticulocyte hemoglobin content: a new frontier in iron deficiency diagnostics for major surgical patients by Suma Choorapoikayil, Mischa J. Kotlyar, Lisa Kawohl, Paul P. Pratz, Denana Mehic, Peter Kranke, Florian Rumpf, Lea V. Blum, Jan A. Kloka, Kai Zacharowski, Vanessa Neef, Patrick Meybohm

“…The ROC curve analysis revealed an AUC of 0.842 (95% CI (0.82–0.87)) at Ret-He cutoff 33.5 pg, by which IDA was discriminated with 69.7% (95% CI (65.3–74.0%)) sensitivity and 85.7% (95% CI (82.3-86.1%)) specificity. …”
Get full text

Роль ендокринних факторів та маркерів клітинного стресу у прогнозуванні ефективності лікування клімактеричного синдрому в період перименопаузи... by I.V. Sokol, D.O. Govsieiev

“…При стандартизації за ІМТ інтегральним показником психопатологічних проявів з урахуванням методу лікування та рівнем антимюлерового гормона виявлено зниження (р=0,039) ризику недосягнення високого ефекту лікування для основної групи, ВШ=0,16 (95% ДІ: 0,07-0,39) порівняно з контрольною групою. Висновки. …”
Get full text

Prognostic role of the pathological status following neoadjuvant chemoradiotherapy and surgery in esophageal squamous cell carcinoma by Xiaofeng Duan, Jie Yue, Shangren Wang, Fangdong Zhao, Wencheng Zhang, Shuo Qie, Hongjing Jiang

“…There were 39 (28.7%) patients with ypT0N0 disease, 49 (36.0%) ypT + N0, 11 (8.1%) ypT0N+, and 37 (27.2%) ypT + N+. …”
Get full text

Cerebrospinal fluid β2-microglobulin promotes the tau pathology through microglia–astrocyte communication in Alzheimer's disease by Zehu Sheng, Lanyang Wang, Ming Chen, Fuxin Zhong, Shijing Wu, Shuyu Liang, Jiaqi Song, Lihua Chen, Yingxi Chen, Shiyu Chen, Weihua Yu, Yang Lü

“…The correlation of CSF β2M with P-tau (proportion = 25.4%, P < 0.001) and T-tau (proportion = 26.7%, P < 0.001) was partially mediated by GFAP in total participants, reproduced in late-life individuals. …”
Get full text

TP53 Mutation Predicts Worse Survival and Earlier Local Progression in Patients with Hepatocellular Carcinoma Treated with Transarterial Embolization by Ken Zhao, Anita Karimi, Luke Kelly, Elena Petre, Brett Marinelli, Erica S. Alexander, Vlasios S. Sotirchos, Joseph P. Erinjeri, Anne Covey, Constantinos T. Sofocleous, James J. Harding, William Jarnagin, Carlie Sigel, Efsevia Vakiani, Etay Ziv, Hooman Yarmohammadi

“…In total, 75 patients (63 men) with a median age of 70.0 (IQR 62.0–76.3) years were included. Of these, 26/75 (34.7%) patients had TP53-mutant HCC. Patients with TP53-mutant HCC had a significantly worse median OS of 15.2 (95% CI, 9.5–29.3) months, versus 31.2 (95% CI, 21.2–52.4) months as the median OS (<i>p</i> = 0.023) for TP53 wild-type HCC. …”
Get full text

Accelerating CO₂ Outgassing in the Equatorial Pacific from Satellite Remote Sensing by Yiwu Shang, Jingyuan Xi, Yi Yu, Wentao Ma, Shuangling Chen

Subjects: “…surface seawater <i>p</i>CO₂…”
Get full text

Diagnosis of tuberculosis in buffaloes in Argentina: intradermoreaction, compatible lesions and bacteriological culture by Emilia Irina Martínez, Fabiana Cipolini Galarza, Nolly María Monzón, Ana Gabriela Espasandin, José Luis Konrad, Elvira Falzoni, Soledad Barandiaran, Jimena Marfil, Marcela Martínez Vivot, Diana Elina Martínez

“…According to these results, the values of sensitivity, specificity, positive and negative predictive values were 0.89; 0.67; 0.8 and 0.8, respectively. In the scenario of a previous unknown situation, this diagnostic method was used as a screening test to avoid transmission, so a highly sensitive test is needed. …”
Get full text

Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…The mean IOP of 16.3±2.1 mm Hg before SLT decreased by 17.1%±9.5% to 13.4±1.9 mm Hg at 12 months after SLT in the first-line group (p&lt;0.001), and the mean IOP of 15.4±1.5 mm Hg before SLT decreased by 12.7%±9.7% to 13.2±2.0 mm Hg at 12 months after SLT (p=0.005) in the second-line group. …”
Get full text

CHARACTERISTICS OF CYTOPROTECTIVE EFFECT ON THE GASTRIC MUCOSA OF CRYOPRESERVED PLACENTA EXTRACT UNDER WATER-IMMOBILIZATION STRESS by Illia Koshurba, Fedir Hladkykh, Mykola Chyzh

“…According to the degree of modulation of the activity of both total NOS and its individual isoforms, the study showed that preventive five-day administration of esomeprazole is inferior to the effectiveness of CEP. Thus, the activity of total NOS in rats administered esomeprazole was statistically significantly (p<0.001) decreased by only 17.1%, while the activity of this enzyme decreased (p<0.001) by 35.8% due to the use of CEP. …”
Get full text

Tibial stem extension versus standard configuration in primary cemented total knee arthroplasty: systematic review and meta-analysis by Arash Heidari, Mohammad H. Ebrahimzadeh, Mahla Daliri, Ali Moradi, Mahdieh Sahebi, Masoumeh Sadeghi

“…The risk of tibial aseptic loosening is 54% lower on average in SE group in comparison with SC group (RR: 0.46; 95% CI: 0.29 to 0.74), which is more notable among obese class I patients (RR: 0.47; 95% CI: 0.28 to 0.78), but not significantly different among obese class II patients (RR: 0.58; 95% CI: 0.19 to 1.78). …”
Get full text

Antimicrobial Residues in Poultry Litter: Assessing the Association of Antimicrobial Persistence with Resistant <i>Escherichia coli</i> Strains by Paula Cortés, Ekaterina Pokrant, Karina Yévenes, Aldo Maddaleno, Andrés Flores, María Belén Vargas, Lina Trincado, Matías Maturana, Lisette Lapierre, Javiera Cornejo

“…A very strong association was observed between the presence of antimicrobial residues and the antimicrobial resistance of <i>E. coli</i> (<i>p</i>-value < 0.0001, and Cramer’s coefficient of 0.47), and an independence between the level of residue concentration and susceptibility (<i>p</i>-value 0.5262). …”
Get full text