Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis by Gong C, Chen J, Zou P, Fang Z, Quan L, Wang J, Yin J, Lin B, Lang J, Chen M

“…CuiCui Gong,1– 3 Junyang Chen,2 Pingjin Zou,2 Zengyi Fang,2 Li Quan,1– 3 Jing Wang,2,4 Jie Yin,2,5 Bing Lin,1 Jinyi Lang,1– 5 Meihua Chen2,3 1School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 610032, People’s Republic of China; 2Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610041, People’s Republic of China; 3Institute of Integrated Traditional Chinese and Western Medicine Cancer Research, Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, People’s Republic of China; 4Department of Oncology, School of Clinical Medicine, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 5School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, 611731, People’s Republic of ChinaCorrespondence: Jinyi Lang, School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, People’s Republic of China, Email langjy610@163.com Meihua Chen, Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, 610041, People’s Republic of China, Email chenmeihua@scszlyy.org.cnPurpose: Radiation-induced pulmonary fibrosis (RIPF) is a serious complication of radiotherapy that lacks effective treatment options. …”
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Do Unresectable Giant Cell Tumors of Bone Treated With Denosumab Progress After Discontinuation of Treatment? by DENO Research Group, Carolina de laCalva, Manuel Angulo, Paula González‐Rojo, Ana Peiró, Pau Machado, Juan Luis Cebrián, Roberto García‐Maroto, Antonio Valcárcel, Pablo Puertas, Gregorio Valero‐Cifuentes, Óscar Pablos, Miriam Maireles, María Luisa Fontalva, Iván Chaves, Aida Orce, Luis Coll‐Mesa, Israel Pérez, Fausto González, María delCarmen Sanz, Isidro Gracia

“…The disease remained stable in 69% of patients (n = 11), with a median recurrence‐free survival time of 46 months (20–157 months) after being treated for a median period of 19 months (5–83 months). …”
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Geochronology and geochemistry of the Neoproterozoic–Mesozoic intrusive rocks in the Xinlin area, northeastern China: new constraints on the tectonic evolution of the Erguna block... by Sheng Lu, Sheng Lu, Sheng Lu, Sheng Lu, Chenglu Li, Masroor Alam, Zhichao Song, Xiannan Zhu, Anzong Fu, Wenpeng Yang

“…Zircon U–Pb and muscovite 40Ar/39Ar geochronology reveal that magmatism occurred during the Neoproterozoic (ca. 864.98 Ma), Early Ordovician (ca. 470.0 Ma), Late Carboniferous (ca. 306.9 Ma), Early Permian (ca. 296.9 Ma), and Early Cretaceous (ca. 117.8 Ma) periods. …”
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

“…Initial experiences with CD19 CAR T cell immunotherapy for patients with B-cell malignancies highlighted the critical impact of intracellular costimulatory domain selection (CD28 vs 4-1BB (CD137)) on CAR T cell expansion and in vivo persistence that may impact clinical outcomes. …”
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Comparison of Suture Anchor Repair and Suture Tape Augmentation for Reconstruction of the Anterior Talofibular Ligament: A Biomechanical Study by Qingfeng Shao, Dahai Hu, Xinru Chen, Huajun Wang, Lei Xiao, Qiang Teng, Jinsong Hong, Huige Hou, Xiaofei Zheng

“…Results The mean load to failure of the STA group (311.20 ± 52.56 N) was significantly higher than that of the intact ATFL group (157.37 ± 63.87 N; p = 0.0016) and the SAR group (165.27 ± 66.81 N; p = 0.0025). …”
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Towards water-conscious green hydrogen and methanol production: A techno-economic review by Henrik Wenzel, Gian Müller, Freia Harzendorf, Thomas Schöb, Felix Kullmann, Jann Michael Weinand, Detlef Stolten

“…Based on the conducted literature review, we find that the long-term median specific energy demand of adsorption-based direct air capture is expected to decrease to 204 kWhel/tCO2 and 1,257 kWhth/tCO2, while the capture cost is expected to decrease to 162 €2024/tCO2, with relative high uncertainty. …”
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Correlations between Traditional and Nontraditional Indicators of Adiposity, Inflammation, and Monocyte Subtypes in Patients with Stable Coronary Artery Disease by Silvia Bueno Garofallo, Vera Lucia Portal, Melissa Medeiros Markoski, Lucinara Dadda Dias, Alexandre Schaan de Quadrosa, Aline Marcadenti

“…Thus, the aim of this study was to evaluate the correlation among indicators of adiposity, monocyte subtypes, and inflammatory markers in patients with stable coronary artery disease (CAD). Methods. This was a cross-sectional study including 97 patients with stable CAD aged >40 years. …”
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How physical activity opportunities seized by adolescents differ between Europe and the Pacific Islands: the example of France and New Caledonia [version 1; peer review: 2 approved... by Olivier Galy, Guillaume Wattelez, Francois Potdevin, Marie-Jeanne Urvoy, Thibaut Derigny, Paul Zongo, Pierre-Yves Leroux, Christophe Schnitzler

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Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective Observational Study by Elizabeth Pando, Piero Alberti, Rodrigo Mata, María José Gomez, Laura Vidal, Arturo Cirera, Cristina Dopazo, Laia Blanco, Concepción Gomez, Mireia Caralt, Joaquim Balsells, Ramón Charco

“…Rise in BUN was the only score related to mortality on the multivariate analysis (p=0.000, OR: 12.7; CI 95%: 4.2−16.6). On the comparative analysis of AUC, the rise in BUN was an accurate test in predicting mortality (AUC: 0.842) and persisting multiorgan failure (AUC: 0.828), similar to the BISAP score (AUC: 0.836 and 0.850) and APACHE-II (AUC: 0.756 and 0.741). …”
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Groundwater vulnerability and, risk assessment of seawater intrusion for the development of a strategy plan towards sustainability: Case of the Souss-Massa coastal area, Morocco by Yassine Ez-zaouy, Lhoussaine Bouchaou, Mohammed Hssaisoune, Abdelhaq Aangri, Gianluigi Busico, Saadou Oumarou Danni, Oumaima Attar, Mohamed Nehmadou, Aicha Saad, Yassine Ait Brahim

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Topical chlorhexidine 0.2% versus topical natamycin 5% for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial by Victor Hu, David Macleod, Helen Anne Weiss, Matthew J Burton, Simon Arunga, Astrid Leck, Sanjay Kumar Singh, Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, Pankaj Chaudhary, Abhishek Roshan, Einoti Matayan

“…Patients are reviewed at day 2, day 7 (with reculture), day 14, day 21, month 2 and month 3. …”
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Evaluation on role of the chest pain nurse in emergency management of patients with ST-elevation myocardial infarction (专职胸痛护士在ST段抬高型急性心肌梗死患者急救中的应用研究)... by QIAN Hongmei (钱宏梅), WEI Yingying (韦莹莹), WANG Yan (王艳)

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Incidence and temporal patterns of true recurrences and second primaries in women with breast cancer: A 10-year competing risk-adjusted analysis by Silvia Mancini, Lauro Bucchi, Annibale Biggeri, Orietta Giuliani, Flavia Baldacchini, Alessandra Ravaioli, Federica Zamagni, Fabio Falcini, Rosa Vattiato

“…Results: The cumulative incidence was 13.7 % (95 % confidence interval (CI), 12.2–15.3 %) for TRs and 4.6 % (95 % CI, 3.7–5.7 %) for SBCs. …”
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Power Transmission for Millimeter-Wave Indoor/Outdoor Wearable IoT Devices Using Grounded Coplanar Waveguide-Fed On-Body Antenna by Fuad Erman, Slawomir Koziel, Alhareth Zyoud, Leifur Leifsson, Ubaid Ullah, Shaker Alkaraki

“…The size of the proposed structure is small and can collect power with high efficiency due to the short wavelength of millimeter wave (mm-wave) in contrast to UHF antennas.…”
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Consumo alimentar e estado nutricional de crianças menores de seis meses acompanhadas na Atenção Primária à Saúde: uma análise temporal de 2016 a 2021 by Caroline Albach, Emilaine Ferreira dos Santos, Nadianne Thais Gabardo Xavier Negrão, Angelica Rocha de Freitas Melhem, Paula Chuproski Saldan

“…Método: Estudo ecológico com base em dados do SISVAN Web, de consumo alimentar (AME) e índices antropométricos (peso/idade, peso/altura, altura/idade e IMC/idade). …”
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Fatal poisonings in Nordic countries in 2022 among people who use drugs by Pirkko Kriikku, Hilde Marie E. Edvardsen, Gunilla Thelander, Svava Thordardottir, Charlotte Uggerhøj Andersen, Ilkka Ojanperä, Anna K. Jönsson, Joachim Frost, Simon Kjær Hermansen, Gerd J.M. Delaveris, Kirsten Wiese Simonsen

“…The death rate (number of deaths per 100,000 inhabitants) among PWUD in 2022 was highest in Norway (8.03), followed by Iceland (7.20) and Finland (5.95), and lowest in Denmark (5.09). …”
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Determination of arsenic and cadmium uptake by rice from topsoil by Desheng Yang, Zhechuan Liu, Wenqi Zhao, Ting Du, Shengyang Fan, Zhuang Xiong, Shaobing Peng, Xiaoxiao Li, Fei Wang

“…TR also decreased shoot As and Cd accumulation by 30.7% and 67.8% at maturity, with topsoil at 12–15 cm depth contributing an average of 2372 μg As m−2 (30.1%) and 138 μg Cd m−2 (66.1%) to total uptake of As and Cd, respectively. …”
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Unraveling Online Mental Health Through the Lens of Early Maladaptive Schemas: AI-Enabled Content Analysis of Online Mental Health Communities by Beng Heng Ang, Sujatha Das Gollapalli, Mingzhe Du, See-Kiong Ng

“…In addition, the EMS features extracted from our dataset averaged 13.27 (SD 3.05) negative features per schema, with 2.65 (SD 1.07) features per dimension, as supported by existing literature. …”
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Evaluación de dietas basadas en grano entero, sin fibra larga, para engorde de bovinos a corral by A. J. Pordomingo, O. Jonas, M. Adra, Juan N. A., M. P. Azcárate

“…Se utilizaron 48 novillitos y 48 novillos Angus, (155 ± 9,7 y 269 ± 10,8 kg de peso vivo) bloqueados por categoría, estratificados por peso en 4 estratos homogéneos, y asignados de a 4 por corral. …”
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Impact of White Blood Cell Count After Percutaneous Coronary Intervention on Long-Term Prognosis in Patients with Unstable Angina Pectoris: A Single-Center Retrospective Observatio... by Zhang Z, Wang H, Wang R, She Z, Liang X, Liu H, Kou X, Wang S

“…Zhiyuan Zhang,1– 3,* Heyan Wang,4,* Ruiyu Wang,5 Zeyu She,6 Xingyue Liang,6 Huiyi Liu,7 Xuemeng Kou,1 Shipeng Wang1– 3 1Department of Cardiology, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 2Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 3State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 4Department of Cardiology, Central Hospital of Dalian University of Technology, Dalian, Liaoning Province, People’s Republic of China; 5Department of Cardiology, the First Affiliated Hospital of Medical School, Xi’an Jiaotong University, Xi’an, Shaanxi Province, People’s Republic of China; 6School of Basic Medicine, Harbin Medical university, Harbin, Heilongjiang Province, People’s Republic of China; 7Department of Cardiology, the First Affiliated Hospital of Peking University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shipeng Wang, Department of Cardiology, 2nd Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, 150086, People’s Republic of China, Tel +86 13654504286, Fax +86 86296225, Email guoyunqaz@126.comObjective: An association between white blood cell count (WBC-C) before percutaneous coronary intervention (PCI) and prognosis has been established in patients undergoing PCI. …”
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