RNA结合蛋白PTBP1与磷酸化-AXL共表达在骨肉瘤中的临床意义 by 李湘湘, 徐雯莉, 卢正宇, 何安芳, 王震, 刘妮, 乐雨婷, 彭挺生

“…免疫组化结果显示PTBP1和p-AXL蛋白的表达在骨肉瘤组织中显著高于非恶性骨组织；p-AXL阳性表达率与肺转移相关（<italic>P</italic>=0.025）；Kaplan-Meier分析发现肺转移、复发、PTBP1表达及PTBP1/p-AXL共表达等因素与骨肉瘤患者不良总生存期相关；且多变量Cox回归分析显示肺转移（<italic>P</italic>&lt;0.000 1）、PTBP1表达阳性（<italic>P</italic>=0.041）是骨肉瘤患者总生存期（OS）独立危险因素；PTBP1/p-AXL共表达患者的OS（<italic>P</italic>=0.017）和PFS（<italic>P</italic>=0.043）均低于非PTBP1/p-AXL共表达患者。…”
Get full text

Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022 by Rebecca F. Wilson, Xin Yue, Karen E. Thomas, Krishna Kiran Kota, Carter J. Betz

“…A larger proportion of fatal CAN among API victims (14.2%; p < 0.05) was precipitated by a crisis than did fatal CAN of Black (3.3%), multiracial (4.7%), and White (4.5%) victims.During 2003–2022, more than one in three (35.9%) fatal CAN victims resided in communities classified as the most impoverished; 52.7% of AI/AN victims resided in these communities, followed by Black (46.7%), Hispanic (31.3%), multiracial (30.9%), White (28.7%), and API (12.4%) victims. …”
Get full text

Experimental Investigation of the Dependence of Accessible Porosity and Methane Sorption Capacity of Carbonaceous Shales on Particle Size by Garri Gaus, Anton Kalmykov, Bernhard M. Krooss, Reinhard Fink

“…Similarly, for the Kimmeridge Clay and Alum Shale, a slight increase of the apparent grain density from 1.546 g/cm3 to 1.552 g/cm3 and from 2.362 g/cm3 to 2.385 g/cm3, respectively, was accompanied by increases in sorption capacity from 0.37 mmol/g to 0.45 mmol/g and from 0.14 mmol/g to 0.185 mmol/g, respectively. …”
Get full text

Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa by Natalie Lissenden, John Bradley, Benjamin Menze, Charles Wondji, Constant Edi, Benjamin Koudou, Raphael N’Guessan, Koama Bayili, Abdoulaye Diabaté, Njelembo Mbewe, Basiliana Emidi, Jacklin Mosha, Alphaxard Manjurano, Graham Small, Welbeck Oumbouke, Sarah Jane Moore, Derric Nimmo, Janneke Snetselaar

“…If the restricted placement of the AIs can exploit mosquito behaviour, particularly where they interact with the bed net interface, and not impact the net’s effectiveness, then the reduction in AI could result in cost reductions. …”
Get full text

屈光性弱视颜色视觉诱发电位的初步研究

“…【目的】 评价弱视的色觉损害以及颜色视觉诱发电位对弱视早期诊断和评价弱视儿童视功能的临床价值,探讨正常儿童屈光不正性弱视儿童屈光参差性弱视儿童的颜色视觉诱发电位的表现和差异【方法】 应用同亮度不同颜色棋盘格的刺激,比较正常儿童屈光不正性弱视儿童屈光参差性弱视儿童的颜色视觉诱发电位【结果】 受试者分为3组,分别为正常儿童组屈光不正性弱视儿童组屈光参差性弱视儿童组①三组儿童组内比较发现:除绿/灰刺激后产生的P1波潜伏期比其它颜色刺激延长之外;其它颜色刺激产生的P1潜伏期两两间的差别无统计学意义各种颜色刺激产生的P1-N2振幅在各组内的差异无统计学意义②正常组和屈光不正组儿童在蓝/灰(P = 0.004)和蓝/黄刺激(P = 0.01)后的P1潜伏期的差别有统计学意义,而其它颜色刺激后的P1潜伏期没有显著差别;在红/灰刺激(P = 0.007)后的P1-N2振幅有显著差别,而其它颜色刺激后的P1-N2振幅没有显著差别③正常组和屈光参差组儿童在蓝/灰(P = 0.02)和蓝/黄刺激(P = 0.01)后的P1潜伏期有显著差别,而其它颜色刺激后的P1潜伏期没有显著差别;正常组和屈光参差组儿童在红/灰(P = 0.005)和黑/白刺激(P = 0.009)后的P1-N2振幅有显著差别,而其它颜色刺激后的P1-N2振幅没有显著差别④屈光不正组和屈光参差组儿童在各种不同颜色刺激后,两组之间的P1潜伏期及P1-N2没有显著差异 (P值均大于0.05)【结论】 正常眼和弱视眼的颜色视觉诱发电位存在差异,而屈光不正性弱视和屈光参差性弱视之间则不存在差异颜色视觉诱发电位可能有助于弱视的早期诊断和视功能评价…”
Get full text

The Prevalence of Depression Among Parkinson&rsquo;s Disease Patients in Saudi Arabia: A Cross-Sectional Study by Al-Qahtani Z, Alqahtani ASM, Alzuhairi AMS, Qarah M, Alqarni AA, Alqahtani AOM, AlShehri FAA, Alqathanin MAA, Alshahrani OMO, Alqahtani MAF, Mahmood SE

“…PD patients lacking social support were 8 times more likely to develop major depression [OR = 8.27, 95% CI (1.47– 46.31), p = 0.016] and 5 times more likely to experience anxiety symptoms [OR = 5.36, 95% CI (1.14– 25.26), p = 0.034]. …”
Get full text

Evaluation of Lyso-Gb1 as a biomarker for Gaucher disease treatment outcomes using data from the Gaucher Outcome Survey by Ari Zimran, Shoshana Revel-Vilk, Tama Dinur, Majdolen Istaiti, Jaco Botha, Elena Lukina, Pilar Giraldo, Patrick Deegan, Stephan vom Dahl

“…Results Of 2007 patients enrolled in the Gaucher Outcome Survey as of February 25, 2022, 435 met the inclusion criteria and were included in the study: 318 treated (‘all treated’; 277 receiving treatment at baseline, 41 treatment naive at baseline), 38 receiving treatment at baseline who stopped treatment before the last lyso-Gb1 assessment, and 79 untreated. …”
Get full text

Heat Re-process approach and thermally integrated renewable energy system for power, compressed hydrogen, and freshwater production; ANN boosted optimization and techno-enviro-econ... by Zhaoyang Zuo, Junhua Wang, Mohammed A. Alghassab, Nashwan Adnan Othman, Ahmad Almadhor, Fahad M. Alhomayani, Hind Albalawi, Samah G. Babiker, Barno Abdullaeva, Aboulbaba Eladeb

Subjects: Get full text

Analysis of the safety and efficacy of flow diverter device in the treatment of tandem aneurysms in the internal carotid artery by Jun Wan, Jun Wan, Ligang Xu, Yeqing Jiang, Lei Zhang, Zhenyu Wang, Xiaolong Zhang, Shengzhang Wang, Shengzhang Wang

“…The median value of maximum aneurysm diameter (Dmax) was 4.27 (3.57–5.41) mm. Among them, 28 aneurysms had a maximum diameter of &lt;5 mm (73.7%), 10 aneurysms had a maximum diameter of 5–15 mm (26.3%). …”
Get full text

Secondary aphakic glaucoma in children: a 15-year retrospective study by N.N. Sadovnikova, V.V. Brzheskiy, M.A. Zertsalova, A.Yu. Baranov

“…Group 1 included children operated on at the age of 90 days and younger; group 2 — aged from 91 to 365 days; group 3 — from 1 year to 4 years 11 months 29 days old; group 4 — from 5 to 10 years old. Co-existing ocular disorders were present in 247 (82,1%) eyes. …”
Get full text

Exposure the role of hydrogen with algae spirogyra biodiesel and fuel-borne additive on a diesel engine: An experimental assessment on dual fuel combustion mode by S. Aravind, Debabrata Barik, Gandhi Pullagura, Sreejesh S.R. Chandran, Elumalai PV, Prabhu Paramasivam, Dhinesh Balasubramanian, Yasser Fouad, Manzoore Elahi M. Soudagar, Md Abul Kalam, Chan Choon Kit

“…For SBD30 + 1.5%DTBP+2%ARCNP+15H2 a shorter ID and CD were observed at 7.2°CA and 34.5 °CA than diesel respectively at full load. …”
Get full text

Exploring the pivotal variables of tongue diagnosis between patients with chronic kidney disease and health participants by Po-Chi Hsu, Po-Chi Hsu, Jia-Ming Chen, Jia-Ming Chen, Chia-Chu Chang, Yu-Jun Chang, Ping-Fang Chiu, John Y. Chiang, John Y. Chiang, Lun-Chien Lo, Lun-Chien Lo

Subjects: “…chronic kidney disease (CKD)…”
Get full text

Right ventricular–pulmonary artery coupling in cardiac resynchronization therapy: evolution and prognosis by Jan Stassen, Xavier Galloo, Kensuke Hirasawa, Surenjav Chimed, Nina Ajmone Marsan, Victoria Delgado, Pieter van derBijl, Jeroen J. Bax

“…On multivariable analysis, TAPSE/PASP ratio <0.45 mm/mmHg (hazard ratio 1.437; 95% confidence interval: 1.145–1.805; P = 0.002) was independently associated with all‐cause mortality, whereas TAPSE <17 mm (hazard ratio 1.237; 95% confidence interval: 0.990–1.546; P = 0.061) was not. …”
Get full text

Delayed Graft Function in Kidney Transplants: Time Evolution, Role of Acute Rejection, Risk Factors, and Impact on Patient and Graft Outcome by Martin Chaumont, Judith Racapé, Nilufer Broeders, Fadoua El Mountahi, Annick Massart, Thomas Baudoux, Jean-Michel Hougardy, Dimitri Mikhalsky, Anwar Hamade, Alain Le Moine, Daniel Abramowicz, Pierre Vereerstraeten

“…Area under the curve of the ROC curve (0.77 [0.74–0.81]) shows an excellent discriminant power of our model, irrespective of rejection. …”
Get full text

SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

Get full text

Influence of colostrum supply on Salmonella spp. seroprevalence in piglet rearing and possibilities to increase colostrum production by optimised feeding by A. Schulte zu Sundern, C. Holling, K. Rohn, J. Schulte-Wülwer, A. Deermann, C. Visscher

“…It could be shown that the colostrum supply can be optimised by providing sows with extra feed. …”
Get full text

CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy by Ashley J. Schlafstein, Allison E. Withers, Soumon Rudra, Diana Danelia, Jeffrey M. Switchenko, Donna Mister, Saul Harari, Hui Zhang, Waaqo Daddacha, Shahrzad Ehdaivand, Xiaoxian Li, Mylin A. Torres, David S. Yu

“…In a Cox proportional hazards model, using a time-dependent covariate to evaluate the risk of death between groups beyond 3 years, high CDK9 expression was significantly associated with an increase in OS (HR: 0.26, 95% CI: 0.07-0.98, p=0.046). …”
Get full text

Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

“…Then, genes in the highest co-expressed module were intersected with the up-regulated DEGs to construct a Protein-Protein Interaction network, resulting in 237 overlapping genes. …”
Get full text

Evaluation and refinement of thresholds for early migration of total knee replacements as an estimator of late aseptic loosening: an updated systematic review of RSA and survival s... by Raymond Puijk, Jiwanjot Singh, Rowan H Puijk, Elise K Laende, José W M Plevier, Peter A Nolte, Bart G C W Pijls

“…Results: After matching studies on PFI, a total of 157 survival and 82 RSA studies were included, comprising 504 study group combinations, 51 different PFIs, and 186,974 TKRs. …”
Get full text

18F-FDG PET/CT在初诊多发性骨髓瘤患者分期的临床应用 by 林志畑

Subjects: Get full text