Vaccines in the fight against antimicrobial resistance – perspectives from South Africa by A Brink, A Kgasi, A Musyoki, B Kagina, C Feldman, D Reddy, E du Toit, E Kalanxhi, J Meyer, I Impalli, M Schönfeldt, M Sibanda, N Schellack, P Skosana, S Essack, S Dlamini, Y Ramsamy

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冠心病临界病变患者残余胆固醇/高密度脂蛋白胆固醇比值水平与冠脉CT血流储备分数的相关性 by 吴祯, 税星, 吴震, 陈泽锋, 陈璘

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Impact of early arterial-phase multidetector CT in blunt spleen injury: a clinical outcomes-oriented study by Yu-Hao Wang, Yu-Tung Wu, Huan-Wu Chen, Yu-San Tee, Chih-Yuan Fu, Chien-Hung Liao, Chi-Tung Cheng, Chi-Hsun Hsieh

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Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis of randomized... by Yining Lu, Julien S. Baker, Shanshan Ying, Yichen Lu

“…The inclusion criteria required glucose and insulin resistance markers to be evaluated pre- and post-intervention among adults who were not trained athletes.ResultsAs a result, twenty studies were included, and meta-analyses were conducted using sixteen studies employing HIIT protocols. Compared with CON, LV-HIIT with reduced intensity and extended interval duration significantly improved fasting glucose (FPG) (mean difference (MD) in mg/dL=-16.63; 95% confidence interval (CI): -25.30 to -7.96; p<0.001) and HbA1c (MD=-0.70; 95% CI: -1.10 to -0.29; p<0.001). …”
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Electromagnetic navigation system for computed tomography-guided synchronous percutaneous lung biopsy and microwave ablation of pulmonary nodules: a prospective, single-center, sin... by Shengwei Li, Zhixin Bie, Yuanming Li, Jie Sun, Jiangxu Zhang, Xiangyu Zi, Runqi Guo, Xiao-Guang Li

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Designing community-based strategies to reach non-household contacts of people with tuberculosis in Lusaka, Zambia: a rapid qualitative study among key stakeholders by Andrew D. Kerkhoff, Marksman Foloko, Evelyn Kundu-Ng’andu, Herbert Nyirenda, Zainab Jabbie, Mainza Syulikwa, Chanda Mwamba, Mary Kagujje, Monde Muyoyeta, Anjali Sharma

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URSA 患者外周血免疫细胞特征及其意义的临床研究

“…【目的】 探讨不明原因复发性流产(URSA)患者处于难免流产和流产后非孕状态等不同临床情况时外周血免疫细胞特征及其临床意义65377; 【方法】 回顾性分析2008-2010年于我院诊疗的自然流产患者184例,就诊时为早期妊娠难免流产的URSA患者55例(URSA难免流产组),同期早期妊娠难免流产的偶发流产患者(sporadic abortion, SA) 23例,作为对照(SA难免流产组)65377;此外,就诊时为未孕状态,距最后一次流产3个月以上URSA患者62例(URSA非孕组),同期未孕状态,距流产3个月以上SA患者44例作为对照(SA非孕组)65377;记录患者一般情况,包括年龄65380;月经周期65377;使用流式细胞术检测外周血免疫细胞,包括T淋巴细胞亚群:T细胞比例65380;Th细胞比例65380;Ts细胞比例65380;Th/Ts;其他免疫细胞:白细胞数量65380;淋巴细胞总数量(LYM细胞)65380;B细胞比例65380;自然杀伤细胞(NK细胞)比例65377;【结果】 难免流产状态:URSA患者与SA患者Th/Ts均异常升高,前者为2.77 ± 5.16,后者为3.67 ± 6.12,URSA患者与SA患者比较,前者NK细胞比例明显升高,为(15.57 ± 6.45)%,后者仅为(11.38 ± 3.66)%,差异有统计学意义(P < 0.05)65377;非孕状态:URSA患者与SA患者比较,URSA患者WBC数量及NK细胞比例高于SA组,前者为(6.27 ± 1.09) × 10965380;(18.26 ± 7.88)%,后者为(5.59 ± 1.16) × 10965380;(11.0 ± 6.8)%,差异有统计学意义(P < 0.05)65377; 【结论】 在发生早期妊娠难免流产时,URSA患者与SA患者均存在一定的免疫紊乱,共同的表现是特异性免疫方面均有Th/Ts异常升高,不同的表现是,URSA患者在非特异性免疫方面存在NK细胞比例增高65377;在非孕状态,SA患者免疫紊乱得到调整回复正常,URSA患者仍然存在一定的免疫紊乱,主要表现在非特异性免疫方面,以WBC数量和NK细胞比例增高为主65377;临床工作中应注意监测URSA患者的免疫状态65377;…”
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升主动脉扩张患者瓣膜置换术后升主动脉的变化 by 黄焕雷, 肖学钧, 卢聪, 范瑞新, 刘菁, 吴若彬

“…升主动脉直径的测量采用心脏超声检查法，测定平面为主动脉根部窦管交界处上方 2 cm 处。以术前升主动脉直径为基础值，按基础值的大小分为直径< 40 mm 组和直径≥ 40 mm 组，并按主动脉瓣形态分为二叶主动脉瓣组和三叶主动脉瓣组。…”
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Effect of Chromium Picolinate and Chromium Nanoparticles Added to Low- or High-Fat Diets on Chromium Biodistribution and the Blood Level of Selected Minerals in Rats by Anna Stępniowska, Jerzy Juśkiewicz, Krzysztof Tutaj, Joanna Fotschki, Bartosz Fotschki, Katarzyna Ognik

“…The metabolism of chromium (Cr), calcium (Ca), phosphorus (P), iron (Fe), copper (Cu), and zinc (Zn) is interconnected, and their deficiency or excessive accumulation may lead to various disturbances, including anemia and diabetes. …”
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NH3 release during the snow evaporation process in typical cities in Northeast China by Xiaoteng Liu, Hongsheng Jia, Yunze Zhao, Yachao Zhang, Haodong Hou, Yingying Xu

“…Significant variations in R were observed across multiple functional areas, which were ranked in descending order as follows: commercial areas (R = 26.16%), residential areas (R = 22.01%), cultural and educational areas (R = 20.7%), and industrial areas (R = 18.01%). The influence of a snow-melting agent (NaCl) on the conversion rate of NH3 initially increased but then subsequently decreased as the dose increased. …”
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Hypothermia during Surgical Treatment of Type A Aortic Dissection: A 16 Years’ Experience by Francesco Macrina, Maria Cristina Acconcia, Luigi Tritapepe, Mizar D’abramo, Wael Saade, Alessandra Capelli, Fabio Miraldi

“…We found a similar trend in other fields of investigations, so we can conclude that circulatory arrest performed at temperature ≥24°C nasopharyngeal temperature associated with ACP is a safe strategy for aortic surgery for AAD.…”
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Development and validation of a diagnostic model for migraine without aura in inpatients by Zhu-Hong Chen, Zhu-Hong Chen, Guan Yang, Chi Zhang, Chi Zhang, Dan Su, Dan Su, Yu-Ting Li, Yu-Xuan Shang, Wei Zhang, Wen Wang

“…Common symptoms like nausea (OR = 0.79, p = 0.43) and vomiting (OR = 0.64, p = 0.17) were not statistically significant predictors for MWoA. …”
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Резолюция Экспертного совета «Диагностика и лечение больных со сладжем в желчном пузыре» by V. T. Ivashkin, Alexey V. Okhlobystin, Dmitry S. Bordin, M. F. Osipenko, E. Ya. Seleznyova, Yu. O. Shulpekova, S. R. Abdulkhakov, O. P. Alexseyeva, I. G. Bakulin, L. G. Vologjhanina, V. B. Grinevich, N. V. Bakulina, T. A. Kolesova, N. V. Korochanskaya, I. V. Putintseva, A. S. Sarsenbayeva, N. S. Yazenok

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Longitudinal changes in the 6-minute walk test and the Glittre-activities of daily living test in adults with cystic fibrosis by Vera Lucia Barros Abelenda, Cláudia Henrique da Costa, Mônica de Cássia Firmida, Raphael Freitas Jaber de Oliveira, Rogério Rufino, Agnaldo José Lopes

“…In relation to the group that did not undergo CP, individuals undergoing CP showed an increase in the 'treatment burden'–CFQ-R between T1 and T2 [16.1 (-3-18) vs. -11.2 (-28-1) points, p=0.049]. …”
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Comparative study of pulpal response following direct pulp capping using synthesized fluorapatite and hydroxyapatite nanoparticles by Eman M. Salem, Omnia M. Abdelfatah, Rania A. Hanafy, Rehab M. El-Sharkawy, Ghadir Elnawawy, Wafaa Yahia Alghonemy

Subjects: “…Direct Pulp Capping…”
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Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia by Selamawit Wondale Begizew, Bethelhem Birhanu Muluneh, Taye Mezgebu Ashine, Asnakech Zekiwos Heliso, Getachew Ossabo Babore, Elias Ezo Ereta, Sentayehu Admasu Saliya, Awoke Girma Hailu, Elias Nigusu Abdisa

“…In multivariate analysis, epileptic patients who had generalized tonic–clonic seizures (adjusted hazard ratio 1.4, 95% CI 1.07–1.84), comorbidities (adjusted hazard ratio 1.3, 95% CI 1.11–1.71), were on polytherapy drug regimens (adjusted hazard ratio 1.80, 95% CI 0.30–2.49), and consumed alcoholic drinks (adjusted hazard ratio 1.5, 95% CI 1.21–1.89) were identified as independent predictors of seizure-related injuries. …”
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Anti-influenza effects of Aloe vera gel on MDCK cells: protective efficacy against ultraviolet-C exposure and analysis of biochemical characteristics and microbial activities by Rasha A. Al-Eisa, Rokayya Sami, Ruqaiah I. Bedaiwi, Roqayah H. Kadi, Suzan A. Abushal, Doaa Mahmoud Johari, Afnan M. Alnajeebi, Reham M. Algheshairy, Abeer A. Abu-Zaid, Sami A. Al-Dhumri

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Prospective clinical performance of CoVarScan in identifying SARS-CoV-2 Omicron subvariants by Kenneth Zhu, Manoj Sah, Lenin Mahimainathan, Yan Liu, Chao Xing, Karen Roush, Andrew Clark, Jeffrey SoRelle

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Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project by Teresa Martín, Catarina Guimarães, Cristina Esquinas, Maria Torres-Duran, Alice M. Turner, Hanan Tanash, Carlota Rodríguez-García, Angelo Corsico, José Luis López-Campos, Eva Bartošovská, Jens-Ulrik Stæhr Jensen, José María Hernández-Pérez, Maria Sucena, Marc Miravitlles

“…Results The study included 1007 individuals, with PI*SS (n = 56; 5.6%), PI*ZZ (n = 578; 57.4%) and PI*SZ (n = 373; 37.0%). The PI*SS population consisted of 58.9% men, with a mean age of 59.2 years and a mean FEV1(% predicted) of 83.4%. …”
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CD28 Genetic Variants Increase Susceptibility to Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Case Control Study by Yangyang Li, Li Jin, Jing Yan, Hong Zhang, Rong Zhang, Cheng Hu

“…Then, we performed a candidate gene association study to identify single-nucleotide polymorphisms (SNPs) associated with DKD susceptibility and further used those SNPs to perform Mendelian randomization analyses of serum sCD28 level and DKD susceptibility. Under additive genetic models, CD28-rs3116494 (OR=1.29 [95% CI 1.11, 1.51], P=0.0011) and CD80-rs3850890 (OR=1.16 [95% CI 1.02, 1.31], P=0.0283) were associated with DKD susceptibility adjusted for age, gender, body mass index (BMI), duration of diabetes, and HbA1c. …”
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