Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation by Bo Ye, Tianzhu Tao, Andong Zhao, Liyuan Wen, Xiaofei He, Yi Liu, Qiang Fu, Weidong Mi, Jingsheng Lou

“…Cytokine expression and microglia activation in brain tissue were determined at 6 h, 12 h, 24 h, 48 h, and day 7 post surgery. Further, septic mice were intracerebral ventricle- (i.c.v.-) injected with recombinant IL-17A, anti-IL-17A ab, anti-IL-17R ab, or isotype controls to evaluate the potential effects of IL-17A/IL-17R blockade in the prevention of SAE. …”
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HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction by Raissa de Miranda Teixeira, Nicole Cruz de Sá, Ana Paula Caires dos Santos, Vanessa Rocha Anjos e Silva, Elaine Christine de Magalhães Cabral Albuquerque, Luiz Claudio Lemos Correia, Ricardo David Couto

“…The HDL particle size, free cholesterol, and hs-CRP analysis showed significant differences when compared between REAMI and CP groups (p<0.0001, p=0.007, and p<0.0001; two-tailed unpaired t-test, respectively). …”
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Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States by Qu Zhang, Yemei Wu, Bo Luo

“…Increased OBS was linked to decreases in waist circumference (WC) (OR 0.41; 95% CI: 0.30–0.51; p &lt; 0.0001), triglycerides (TG) (OR 0.71; 95% CI: 0.53–0.92; p = 0.0139), blood pressure (BP) (OR 0.53; 95% CI: 0.40–0.69; p &lt; 0.0001), and fasting glucose (FG) (OR 0.61; 95% CI: 0.45–0.81; p &lt; 0.0001), while HDL-C increased (OR 0.68; 95% CI: 0.51–0.90; p = 0.0065). …”
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Omega-3 Fatty Acids: Key Players in Cognitive Function and Brain Health by Wiktoria Wesołowska, Emilia Bachoń, Michalina Doligalska, Aleksandra Stremel, Agnieszka Leszyńska, Julia Linke, Zuzanna Bałoniak, Dominika Kozłowska, Julia Bałoniak, Weronika Tuszyńska

“…In mental health, omega-3s can help reduce symptoms of depression and schizophrenia, although effectiveness depends on dosage and the EPA to DHA ratio. …”
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Disparities in stage at diagnosis of head and neck tumours in Brazil: a comprehensive analysis of hospital-based cancer registriesResearch in context by Flávia Nascimento de Carvalho, Marianna de Camargo Cancela, Luciano Mesentier da Costa, Luís Felipe Leite Martins, Fernando Luiz Dias, Dyego Leandro Bezerra de Souza, Luis Felipe Ribeiro Pinto

“…Findings: Among 145,365 HNSCC cases, 78.2% (90,267/115,371) were diagnosed at stages III or IV. …”
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Following Up Patients With Chronic Pain Using a Mobile App With a Support Center: Unicenter Prospective Study by Marta Antonia Gómez-González, Nicolas Cordero Tous, Javier De la Cruz Sabido, Carlos Sánchez Corral, Beatriz Lechuga Carrasco, Marta López-Vicente, Gonzalo Olivares Granados

“…By the end of the study, 19 (29.7%) patients remained in the pretreatment phase, 8 (12.5%) patients had completed the trial phase, and 37 (57.8%) reached the implantation phase. …”
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Construction and evaluation of a triage assessment model for patients with acute non-traumatic chest pain: mixed retrospective and prospective observational study by Xuan Zhou, Gangren Jian, Yuefang He, Yating Huang, Jie Zhang, Shengfang Wang, Yunxian Wang, Ruofei Zheng

“…Clinical trial registration number: ChiCTR2200061918.…”
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Lerociclib plus fulvestrant in patients with HR+/HER2− locally advanced or metastatic breast cancer who have progressed on prior endocrine therapy: LEONARDA-1 a phase III randomize... by Binghe Xu, Qingyuan Zhang, Yang Luo, Zhongsheng Tong, Tao Sun, Changping Shan, Xinlan Liu, Yumin Yao, Bing Zhao, Shusen Wang, Xiaohua Zeng, Changlu Hu, Xi Yan, Xiaojia Wang, Hongyan Jia, Zhendong Chen, Fuming Qiu, Xinhong Wu, Deyong Zhang, Tong Li

“…Progression-free survival (PFS) assessed by investigators was significantly improved in lerociclib arm versus placebo arm (11.07 vs 5.49 months; hazard ratio, 0.451, 95% CI: 0.311-0.656, P = 0.000016), meeting the pre-specified primary endpoint. …”
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High-Fiber Crackers Supplemented with Asparagus Hard-Stem: Impacts of Supplementation Ratios and Water Amounts in Cracker Recipe on the Product Quality by Thi Thu Tra Tran, Le Hong Ngoc Ngo, Nu Minh Nguyet Ton, Thi Hong Nhung Le, Thi Thuy Le, Van Viet Man Le

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The change rule of smoke dispersion and temperature evolution in fires within lithium iron phosphate energy storage prefabricated cabin by ZHANG Yin, QIN Chaoqun, TIAN Shuangshuang, GE Zhichao, DONG Jun, ZHANG Xiaoxing

“…The research results in the article can provide theoretical guidance for the distributed deployment strategy in energy storage prefabricated cabin and fire safety design of monitoring and warning devices.…”
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Comparative Evaluation of the Effectiveness of Manual and Electric Toothbrushes in Blind Children: A Randomised Controlled Trial by PS Thanalakshme, R Ramesh

“…Furthermore, compared to Group 2 (32.7±5.3 to 11.7±3.7), dental anxiety decreased more in Group 1 (32.8±5.3 to 7.9±3.2). …”
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A multi-layer neural network-based evaluation of MHD radiative heat transfer in Eyring–Powell fluid model by Muflih Alhazmi, Zahoor Shah, Muhammad Asif Zahoor Raja, Nafisa A. Albasheir, Maryam Jawaid

“…The obtained outcomes indicate that the model built and implemented utilizing a neural network offers precise performance ranging from 3.25E-13 to 5.41E-13 with a mean error of around 3.25E-13, 1.56E-11, 5.41E-13, 2.97E-12, 1.03E-11, 2.05E-12, 1.49E-12, and 5.01E-12, across eight different circumstances, suggesting improved capability and reliability of the developed predictive model. …”
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Asociación entre depresión y deterioro cognitivo en adultos mayores de un centro de atención integral de Lima by Juliet Guillén, Carlos David Neyra Rivera, Fernando Runzer Colmenares, Ericson Gutiérrez

“…<br /><strong>Resultados: </strong>El promedio de edad fue de 67,4± 7,4 años. El 20,7% presentó depresión y el 31,0% deterioro cognitivo. …”
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Induced Inflammatory and Oxidative Markers in Cerebral Microvasculature by Mentally Depressive Stress by Yuequan Zhu, Yazeed Haddad, Ho Jun Yun, Xiaokun Geng, Yuchuan Ding

“…A total of forty 6-week-old male C57BL/6J mice were randomly divided into the CRS and control groups. …”
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Establishment of a Breeding Approach Combined with Gamma Ray Irradiation and Tissue Regeneration for Highbush Blueberry by Xuan Yu, Haidi Yuan, Yihong Jin, Chuizheng Xia, Jiani Zhu, Jiali Che, Jiao Yang, Xiaofei Wang, Bingsong Zheng, Shufang Yang, Cristian Silvestri, Fuqiang Cui, Jianfang Zuo

“…We established a high-efficiency regeneration protocol, which was applied to leaves and stems exposed to gamma irradiation using ⁶⁰Co-γ rays at doses of 10, 20, 40, 80, and 120 gray (Gy), to increase the efficiency of mutated cells to develop into adventitious shoots. …”
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Anemia in pregnancy: a systematic review and meta-analysis of prevalence, determinants, and health impacts in Egypt by Ahmed Azzam, Heba Khaled, Alrefaey K. Alrefaey, Amar Basil, Sarah Ibrahim, Mohamed S. Elsayed, Muhammad Khattab, Nashwa Nabil, Esraa Abdalwanees, Hala Waheed Abdel Halim

“…The sensitivity analysis demonstrated the absence of influential outliers and Egger’s test indicated no evidence of publication bias (P = 0.17). Anemia prevalence was significantly higher in the third trimester (65%) compared to the second trimester (47%) (P = 0.03). …”
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Anemia, Thrombocytopenia, and Changes in Biochemical Parameters Occurring in Patients with Uncomplicated Plasmodium falciparum Malaria: Data Analysis from Antimalarial Efficacy-Ran... by Khadime Sylla, Roger Tine, Doudou Sow, Souleye Lelo, Annie Abiola, Jean Louis NDiaye, Magatte NDiaye, Kuaku Folly, Léon Amath NDiaye, Oumar Gaye, Babacar Faye

“…Male subjects represented 58.47% (sex ratio was 1.4 for males). The mean hemoglobin level at inclusion (D0) was 9.79 g/dl and anemia (Hb<11 g/dl) was 71.43% (aOR=1.16 0.68−1.98p=0.57). …”
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A complete structural analysis of the FⅠ17 strike-slip fault and its hydrocarbon enrichment factors, Tarim basin, NW China by Shi Chen, Shi Chen, Xinxin Liang, Xinxin Liang, Xingguo Song, Xingguo Song, Yintao Zhang, Zhou Xie, Yuan Neng, Yuan Neng, Pengfei Kang, Jianxun Zhou, Jianxun Zhou

“…The FⅠ17 fault is a prominent strike-slip fault in the central Tarim basin, notable for its hydrocarbon abundance and intricate tectonic attributes, characterized by several deflections in its planar trajectory. …”
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Rationale and design for the thoracic Paravertebral Adjunctive Dexamethasone Palmitate Reducing chronic pain After cardiac surgery (PANDORA) trial: a parallel-group, double-blinded... by Jing Zhao, Hui Zhang, Ziyu Zheng, Baobao Gao, Lini Wang, Chong Lei, Hailong Dong, Taoyuan Zhang, Jiao Gao, Lihong Hou

“…The nature and intensity of pain will be evaluated with a Brief Pain Inventory Short Form (BPI-SF) questionnaire.Ethics and dissemination The trial was approved by the Ethics Committee of Xijing Hospital, the First Affiliated Hospital of Air Force Military Medical University (KY20232194-C-1). Results will be submitted for publication in peer-reviewed journals and presented at academic meetings.Trial registration number ClinicalTrials.gov, NCT05920967.…”
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Trends and Variability of PM2.5 at Different Time Scales over Delhi: Long-term Analysis 2007–2021 by Chetna, Surendra K. Dhaka, Gagandeep Longiany, Vivek Panwar, Vinay Kumar, Shristy Malik, A. S. Rao, Narendra Singh, A. P. Dimri, Yutaka Matsumi, Tomoki Nakayama, Sachiko Hayashida

“…The long-term PM2.5 concentration showed an overall small but statistically significant decreasing trend with an average decrease of −1.35 (95% CI: −2.3, −0.47) µg m−3 year−1. Seasonal trends revealed a significant decreasing value of −3.05 µg m−3 year−1 (p < 0.1) for summer, an insignificant declining trend of −1.95 µg m−3 year-1 for monsoon. …”
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