Application of N-Acetyl-Glucosaminil-N-Acetyl-Muramyl Dipeptide during Triple Component Anti-Helicobacter Pylori Therapy in the Period of Coronavirus Infection COVID-19 by M. R. Konorev, E. N. Tyshevich, R. A. Pavlyukov

“…The frequency of adverse reactions depending on ITT and PP: OCA — 24 % (95 % CI: 16-33) and 26 % (95 % CI: 17-35); OCAL1 — 2 % (95 % CI: 0.01-8) and 2 % (95 % CI: 0.01-8); OCAL10 — 2 % (95 % CI: 0.01-7) and 2 % (95 % CI: 0.01-7). …”
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Psychological Status and Related Factors in Medical Isolated Persons during Outbreak of COVID-19 by Qin WANG, LI Li, Xia ZHOU, Zhimei LIU, Bingshan GUO, Renqi DONG

“…The General Anxiety Disorder Scale-7 (GAD-7) was used to evaluate anxiety state, and the Patient Health Questionnaire-9 (PHQ-9) depression screening scale was used to evaluate depression state.Results:1) Among the 124 medical isolation residents,106 (85.48%) had anxiety-related mood changes (GAD-7&gt;4) and 96 (77.42%) had depression-related mood changes (PHQ-9&gt;4).2) Univariate analysis showed that the educational level, the scores of GAD-7 were statistically significant with different educational levels, the amount of negative information received about the COVID-19 and occupational classification (<italic>P</italic>=0.03, <italic>P</italic>=0.002, <italic>P</italic>=0.04), while the scores of PHQ-9 were statistically significant with different marital status, educational levels, occupational classification (<italic>P</italic>=0.04, <italic>P</italic>=0.002, <italic>P</italic>=0.02).3) Multiple <italic>Logistic</italic> regression analysis showed that the amount of negative information received about the COVID-19 (<italic>OR</italic>=2.855, <italic>P</italic>&lt;0.001) was a risk factor for anxiety among medical isolated persons during the epidemic, while there was a protective factor in educational level (<italic>OR</italic>=0.656, <italic>P</italic>=0.175). …”
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Wildfire indicators modeling for reserved forest of Vellore district (Tamil Nadu, India) by Yara EzAl Deen Sultan, Kanni Raj Arumugam Pillai, Archana Sharma

“…The Vellore district, covering 6,077 square kilometers, has a significant 27% forest cover, covering 162,286 ha. …”
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The evolutionary history of Plasmodium falciparum from mitochondrial and apicoplast genomes of China-Myanmar border isolates by Yini Tian, Run Ye, Dongmei Zhang, Yilong Zhang

“…Methods We have sequenced the whole mt/apico genome of 34 CMB field isolates and utilized a published data set of 147 mt/apico genome sequences to present global genetic diversity and to revisit the evolutionary history of the CMB P. falciparum. …”
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Development and validation of a UV/visible spectrophotometric method for simultaneous assay of paracetamol and ibuprofen by Timothée Mavanga Mabaya, Jocelyn Mankulu Kakumba, Mannix Mayangi Makola, Adelard Mbenza Puati, Didi Mana Kialengila, Jean Mavar Tayey Mbay, Jérémie Mbinze Kindenge

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Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015) by Won Kyoung Cho, Hyo-Kyoung Nam, Jae Hyun Kim, Young-Jun Rhie, Sochung Chung, Kee-Hyoung Lee, Byung-Kyu Suh

“…Study participants were classified into normal weight [body mass index (BMI) below 85th percentile, 80.7%], overweight (85th ≤ BMI< 95th percentile, 8.7%), and obesity (BMI ≥ 95th percentile, 10.6%). …”
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Occupational outcomes of people with multiple sclerosis: a scoping review by Guglielmo Dini, Alfredo Montecucco, Nicoletta Debarbieri, Paolo Durando, Giuliana Buresti, Benedetta Persechino, Matilde Inglese, Bruno Kusznir Vitturi, Alborz Rahmani, Elvira Sbragia, Paolo Bandiera, Michela Ponzio, Mario Alberto Battaglia, Tommaso Manacorda

“…Concerning the occupational outcomes, studies mostly addressed unemployment (311, 77.2%), early retirement (120, 29.8%), disability pension (117, 29.0%), sick leave (77, 19.1%), the indirect cost of MS (74, 18.4%) and work characteristics (57, 14.1%). …”
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Non-communicable diseases and their associations with outpatient services utilisation: insight from a population-based survey in Malaysia by Jabrullah Ab Hamid, Awatef Amer Nordin, Suhana Jawahir, Adilius Manual, Iqbal Ab Rahim, Sarah Nurain Mohd Noh, Nur Elina Ab Mutalib, Nurul Salwana Abu Bakar

“…Adults with multimorbidity were high users of outpatient services (20.4%, 95% CI=17.5–23.7), approximately threefold of adults with no non-communicable diseases. …”
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Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos by Yuxin Chen, Ziwen Yang, Zhiqiang Guo, Lemei Zhan, Kenneth B. Storey, Danna Yu, Jiayong Zhang

“…The present study quantified the transcript levels of mitochondria protein-coding genes (mtPCGs) using quantitative real-time polymerase chain reaction (<i>RT-qPCR</i>) in samples of larvae of three dragonfly species (<i>A. parthenope</i>, <i>E. elegans</i>, and <i>G. confluens</i>) under different levels of CPF stress. By exposing larvae from uncontaminated populations to 0.05 μg/L CPF for 24 h, the transcript levels of seven mtPCGs in <i>A. parthenope</i> were significantly increased (<i>p</i> < 0.05) by 1.89 ± 0.42-fold for <i>COI</i>, 4.30 ± 0.24-fold for <i>COIII</i>, 5.94 ± 0.17-fold for <i>ND1</i>, 4.69 ± 0.56-fold for <i>ND2</i>, 3.44 ± 0.48-fold for <i>ND4</i>, 2.19 ± 0.53-fold for <i>ND4L</i>, and 5.05 ± 0.36-fold for <i>Cytb</i>, respectively. …”
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Ensiling and thermic treatment effects on ruminal carbohydrate fermentation and post-ruminal crude protein concentration in partial-crop peas and faba beans by M. Bachmann, P. Okon, F. Pilger, C. Kuhnitzsch, S.D. Martens, O. Steinhöfel, A. Zeyner

“…Toasting was simulated in a drying oven at 160 °C for 60 min. Post-incubation pH and gas accumulation profiles were little affected by treatment. …”
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Clinical efficacy and hemodynamic effects of levosimendan in cardiac surgery patients after surgery by Meiling Zhao, Yunfeng Hou, Meng Yuan, Shuang Ma, Yifeng Yue

“…Post-treatment, the research group demonstrated a significant reduction in CVP (9.25 ± 2.11 cmH2O vs. 11.36 ± 3.08 cmH2O, P < 0.001), heart rate (100.30 ± 8.69 bpm vs. 105.74 ± 7.69 bpm, P < 0.001), and lactic acid levels (1.68 ± 0.59 mmol/L vs. 2.69 ± 0.55 mmol/L, P < 0.001). …”
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Association between childhood immunisation coverage and proximity to health facilities in rural settings: a cross-sectional analysis of Service Provision Assessment 2013–2014 facil... by Ahmad Reza Hosseinpoor, Nicole E Johns, Mike Chisema, M Carolina Danovaro-Holliday, Katherine Kirkby, Anne Schlotheuber, Messeret Shibeshi, Samir V Sodha, Boston Zimba

“…In adjusted comparisons, how close a child was to a health facility remained meaningfully associated with how likely they were to have received rotavirus vaccine (adjusted OR (AOR) 1.63, 95% CI 1.13 to 2.33) and measles vaccine (AOR 1.62, 95% CI 1.11 to 2.37).Conclusion Proximity to health facilities was significantly associated with likelihood of receipt for some, but not all, vaccines. …”
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Predicting abatacept retention using machine learning by Rieke Alten, Claire Behar, Pierre Merckaert, Ebenezer Afari, Virginie Vannier-Moreau, Anael Ohayon, Sean E. Connolly, Aurélie Najm, Pierre-Antoine Juge, Gengyuan Liu, Angshu Rai, Yedid Elbez, Karissa Lozenski

“…Results The pooled ACTION and ASCORE dataset included 5320 patients with RA (mean [standard deviation] age 57.7 [12.7] years; 79% female). The 12-month abatacept retention rate was 61% (n = 3236) with a discontinuation rate of 39% (n = 2037). …”
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Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency by Boonchai Boonyawat, Tim Phetthong, Nithipun Suksumek, Chanchai Traivaree

“…All affected males were hemizygous for G6PD mutations and had an average G6PD level of 16.7 ± 11.5 (3–76) IU/ml.RBC. Majority of female patients (27 in 29, 93.1%) were heterozygous for G6PD mutations and had an average G6PD level of 133.6 ± 43.4 (9–195) IU/ml.RBC. …”
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Eliciting Preferences for the Uptake of Smoking Cessation Apps: Discrete Choice Experiment by Dorothy Szinay, Rory A Cameron, Andy Jones, Jennifer A Whitty, Tim Chadborn, Jamie Brown, Felix Naughton

“…Relative to other attributes, a 4.8-star user rating, representing social proof, was the strongest driver of app selection (mean preference parameter 2.27, SD 1.55; 95% CI 1.95-2.59). Participants preferred an app developed by health care–orientated trusted organization (credible source) over a hypothetical company (mean preference parameter 0.93, SD 1.23; 95% CI 0.72-1.15), with a logo and screenshots over logo only (mean preference parameter 0.39, SD 0.96; 95% CI 0.19-0.59), and with a lower monthly cost (mean preference parameter –0.38, SD 0.33; 95% CI –0.44 to –0.32). …”
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Artificial intelligence-assisted platform performs high detection ability of hepatocellular carcinoma in CT images: an external clinical validation study by Rongxue Shan, Chenhao Pei, Qianrui Fan, Junchuan Liu, Dawei Wang, Shifeng Yang, Ximing Wang

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Understanding “Alert Fatigue” in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders by Illin Gani, Ian Litchfield, David Shukla, Gayathri Delanerolle, Neil Cockburn, Anna Pathmanathan

“…ConclusionsWhile GPs acknowledged that CRs, when used optimally, can enhance patient safety and quality of care, several concerns emerged regarding their design, content accuracy, and lack of contextual nuance. …”
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Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis by Karen M. Gilbert, PhD, Robert F. LeCates, MA, Alison A. Galbraith, MD, MPH, Paul J. Maglione, MD, PhD, Stephanie Argetsinger, MPH, Nicholas L. Rider, DO, Jocelyn R. Farmer, MD, PhD, Mei-Sing Ong, PhD

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A multicenter micro-costing analysis of flexible cystoscopic procedures in Korea by Uiemo Je, Woong Kyu Han, Hee-Kyo Jeong, Hankil Lee, Kwang Suk Lee, Sung Ku Kang, Byeong-Ju Kwon, Sung-Uk Kuh

“…Cystoscopy costs at GSH were driven by reprocessing ($45.8, 45.4%) and equipment ($33.1, 32.9%), while NHIMC’s were $52.5 (44.0%) for equipment and $48.7 (40.8%) for reprocessing. Both hospitals incurred financial losses, with NHIS (National Health Insurance Service) covering only about 71.7% and 60.6% of costs for cystoscopy, and 71.0% and 62.7% for JJ stent removal. …”
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Impact of Antimicrobial Stewardship and Infection Prevention and Control Programmes on Antibiotic Usage and A. baumannii resistance: A 2016&ndash;2023 Multicentre Prospective Study by Liu L, Liu B, Li L, Li Y, Zhou X, Li Q

“…The major categories of the AB clinical strains collected were extracted primarily from patients’ respiratory tract specimens, the ICU wards and patients over 65 years old, accounting for 76.98%, 67.98% and 63.72%, respectively. The incidence of CR-AB, MDR-AB and XDR-AB based on AMS and IPCP measures ranged from 70.04% to 58.42% (P< 0.0001), 64.26% to 52.16% (P< 0.0001) and 2.27% to 0.60% (P=0.0167), respectively. …”
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