Expression of Sclerostin in Osteoporotic Fracture Patients Is Associated with DNA Methylation in the CpG Island of the SOST Gene by Yanming Cao, Bin Wang, Ding Wang, Dongxiang Zhan, Caiyuan Mai, Peng Wang, Qiushi Wei, Yamei Liu, Haibin Wang, Wei He, Liangliang Xu

“…The aim of this study is to investigate the involvement of CpG methylation in regulation of SOST expression in patients with primary osteoporosis. …”
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Comparison between Endoscopic Ultrasound-Guided Antegrade and Transluminal Stent Implantation in Distal Malignant Biliary Obstruction after Failed ERCP by Yonghua Shen, Ying Lv, Xiaojiao Zheng, Wei Zhan, Senlin Hou, Lin Zhou, Jun Cao, Bin Zhang, Lei Wang, Hao Zhu, Lichao Zhang

“…Distal malignant biliary obstruction (DMBO) can result in obstructive jaundice. Endoscopic ultrasound- (EUS-) guided biliary drainage (EUS-BD) has been an alternative for DMBO after failed ERCP. …”
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Prospective Study on Retinal Nerve Fibre Layer Thickness Changes in Isolated Unilateral Retrobulbar Optic Neuritis by Gordon S. K. Yau, Jacky W. Y. Lee, Patrick P. K. Lau, Victor T. Y. Tam, Winnie W. Y. Wong, Can Y. F. Yuen

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Exploring Acute Kidney Injury Incidence in Hip Periprosthetic Joint Infection Treatment With Combined Intravenous and Intra-articular Antibiotic Infusion by Wenbo Mu, MD, PhD, Boyong Xu, MD, Fei Wang, MD, Wentao Guo, MD, PhD, Xiaogang Zhang, MD, Li Cao, MD

“…Results: Among 151 patients, 17 (11.26%) developed AKI, with 13 cases resolving transiently before discharge. …”
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CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding by Qihong Yang, Liangyu Cai, Mila Wang, Guiyun Gan, Weiliu Li, Wenjia Li, Yaqin Jiang, Qi Yuan, Chunchun Qin, Chuying Yu, Yikui Wang

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Association between poor oral health and deterioration of appetite in older age: results from longitudinal analyses of two prospective cohorts from the UK and USA by Sheena E Ramsay, Olia Papacosta, S Goya Wannamethee, John C Mathers, Peter H Whincup, Lucy Lennon, Ziyi Cai, Suruchi G Ganbavale, Robert Weyant

“…In the HABC Study, self-rated oral health ((OR=1.13 (95% CI=1.01 to 1.27)), tooth loss (OR=1.78 (95% CI=1.15 to 2.76)), dry mouth (OR=1.76 (95% CI=1.02 to 3.03)), eating or chewing difficulty (OR=1.88 (95% CI=1.41 to 2.50)) and cumulative oral health problems (OR=1.89 (95% CI=1.33 to 2.70)) at baseline were associated with sustained poor/deterioration in appetite during follow-up. …”
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Trio-based whole-exome sequencing reveals mutations in early-onset high myopia by Ding Chen, Xiu-Feng Huang, Juan Huang, Yi-Ming Guo, Junhan Wei, Lu Ye, Yi-Xin Cai, Jiejing Bi, Fen-Fen Li

“…Subsequently, computational methodologies were employed for functional annotations and pathogenicity assessments.Results Our investigation identified 7 genes and 10 variants associated with HM across 7 families, including a novel mutation in the ARR3 gene (c.139C>T, p.Arg47*) and two mutations in the P3H2 gene (c.1865T>C, p.Phe622Ser and c.212T>C, p.Leu71Pro). …”
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Single‐cell dissection reveals immunosuppressive F13A1+ macrophage as a hallmark for multiple primary lung cancers by Chenglin Yang, Jiahao Qu, Jingting Wu, Songhua Cai, Wenyi Liu, Youjun Deng, Yiran Meng, Liuqing Zheng, Lishen Zhang, Li Wang, Xiaotong Guo

“…This subtype overexpresses M2 macrophagemarkers and exhibits up‐regulation of SPP1‐CD44/CCL13‐ACKR1 interactions, indicatingits role in shaping the immunosuppressive tumour microenvironment and promotingtumour growth in MPLCs. …”
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Toxicological complexity of microplastics in terrestrial ecosystems by Fazal Ullah, Peng-Yang Wang, Saddam Saqib, Ling Zhao, Muhammad Ashraf, Aziz Khan, Wasim Khan, Adnan Khan, Yinglong Chen, You-Cai Xiong

“…Additionally, the review highlights how MPs can serve as vectors for toxins to damage soil health and species survival. …”
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The Genetic Diversity, Population Structure, and Historical Dynamics of Wild <i>Pyrus</i> Species on the Yunnan–Kweichow Plateau by Xiang Yang, Xingguang Dong, Kunming Li, Ying Zhang, Chenxi Xu, Hongliang Huo, Luming Tian, Jiayu Xu, Chao Liu, Dan Qi, Yufen Cao

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A UV to X-Ray View of Soft Excess in Type 1 Active Galactic Nuclei. I. Sample Selection and Spectral Profile by Shi-Jiang Chen, Jun-Xian Wang, Jia-Lai Kang, Wen-Yong Kang, Hao Sou, Teng Liu, Zhen-Yi Cai, Zhen-Bo Su

“…Of the sources, ≈71% (42/59) exhibit power-law-like (po-like) soft excess, while ≈29% (17/59) exhibit blackbody-like (bb-like) soft excess. …”
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Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing by Lei Jin, Liang Zhou, Jian-Biao Wang, Li Tao, Xiao-Xiao Lu, Na Yan, Qian-Ming Chen, Li-Ping Cao, Lei Xie

“…However, when we looked at tumor size, we found that if the tumor was at least 5 millimeters in size, there was a higher chance of it being at high risk for PTM (P<0.001, odds ratio (OR) = 2.55, 95% confidence interval (CI): 1.57–4.14). Identification of BRAFV600E mutation was not demonstrated to be significantly correlated with advanced clinicopathological characteristics, although it was strongly associated with a bigger tumor diameter (OR = 4.92, 95% CI: 2.40–10.07, P<0.001). …”
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The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma by Le-Bin Song, Jiao-Chen Luan, Qi-Jie Zhang, Lin Chen, Hao-Yang Wang, Xue-Chen Cao, Ning-Hong Song, Yan Lu

“…In the multivariate Cox model, the gene signature was testified as a remarkable prognostic factor (HR=45.423, P<0.001). …”
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RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6 by Lizhe Wang, Yu Wang, Yueyang Li, Li Zhou, Sihan Liu, Yongyi Cao, Yuzhi Li, Shenting Liu, Jiahui Du, Jin Wang, Ting Zhu

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Subtle genomic differences in Klebsiella pneumoniae sensu stricto isolates indicate host adaptation by Bridget O'Brien, Alla Yushchenko, Jinha Suh, Dongyun Jung, Zhangbin Cai, Ngoc Sang Nguyen, Makeda Semret, Simon Dufour, Séamus Fanning, Jennifer Ronholm

“…Klebsiella pneumoniae sensu stricto (KpI) is an opportunistic pathogen capable of residing as a commensal in both human and bovine intestinal tracts and can cause serious systemic infections in humans and severe clinical mastitis in dairy cattle. …”
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Machine learning identification of a novel vasculogenic mimicry-related signature and FOXM1’s role in promoting vasculogenic mimicry in clear cell renal cell carcinoma by Chao Xu, Sujing Zhang, Jingwei Lv, Yilong Cao, Yao Chen, Hao Sun, Shengtao Dai, Bowei Zhang, Meng Zhu, Yuepeng Liu, Junfei Gu

“…Background: Clear Cell Renal Cell Carcinoma (ccRCC), the predominant subtype of renal cell carcinoma (RCC), ranks among the most common malignancies worldwide. …”
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A clinical study exploring the prediction of microvascular invasion in hepatocellular carcinoma through the use of combined enhanced CT and MRI radiomics. by Jiangfa Li, Wenxiang Song, Jixue Li, Lv Cai, Zhao Jiang, Mengxiao Wei, Boming Nong, Meiyu Lai, Yiyi Jiang, Erbo Zhao, Liping Lei

“…The 93 patients were randomly divided into training and validation groups in 7:3 ratio. The imaging data of patients, including CT and MRI, were collected and processed using 3D Slicer to delineate the region of interest (ROI) for each tumor. …”
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A Pervasive Approach to EEG-Based Depression Detection by Hanshu Cai, Jiashuo Han, Yunfei Chen, Xiaocong Sha, Ziyang Wang, Bin Hu, Jing Yang, Lei Feng, Zhijie Ding, Yiqiang Chen, Jürg Gutknecht

“…The results showed that K-Nearest Neighbor (KNN) had the highest accuracy of 79.27%. The result also suggested that the absolute power of the theta wave might be a valid characteristic for discriminating depression. …”
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Several Geological Issues of Schrödinger Basin Exposed by CE-2 CELMS Data by Z. G. Meng, H. H. Wang, Y. C. Zheng, Y. Z. Wang, H. Miyamoto, Z. C. Cai, J. S. Ping, Y. Z. Zhu

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A multi-modal dental dataset for semi-supervised deep learning image segmentation by Yaqi Wang, Fan Ye, Yifei Chen, Chengkai Wang, Chengyu Wu, Feng Xu, Zhean Ma, Yi Liu, Yifan Zhang, Mingguo Cao, Xiaodiao Chen

“…Additionally, deep learning for tooth segmentation can focus on relevant treatment information and localize lesions. …”
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