Parastomal hernia repair: A 10-year retrospective study at District General Hospital—Recurrence and complications by Ali Javaid, Karim Muhammad, Nafees Qureshi

“…There were 29 male and 18 female patients, with a male:female ratio of 67.75%:38.3%. There were 29 cases with colostomy (61.7%) and 18 cases with a history of ileostomy formation (38.3%). …”
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Gut microbiota and kidney function in autosomal dominant polycystic kidney disease participants in Cameroon: a cross-sectional study by Inès Obolo Nwaga, Victorine Bandolo Nzana, Rhoda Nsen Bughe, Isaac Dah, Cheboh Cho-Fon, Maimouna Mahamat, Emmanuelle Ndjong, Aristide Nono, Jean Claude Mballa, Fon Abongwa Acho, Vicky Ama Moor, Wilfred Fon Mbacham, François Folefack Kaze

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Assessing cross-country inequalities in global burden of gastrointestinal cancers: slope and concentration index approach by Haoyun Zhou, Yongbo Wang, Fang Wang, Runtang Meng, Yong Yu, Su Han, Yu Zhang, Yu Wu, Xiaoxue Liu

“…Moreover, the slope index changed from 358.42 (95% confidence interval 343.28 to 370.49) to 245.13 (217.47 to 271.24) for CRC, from − 63.88 (− 87.48 to − 48.28) to − 1.36 (− 32.44 to 25.87) for EC, and from 126.37 (101.97 to 146.47) to 58.04 (20.54 to 96.12) for GC. …”
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Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG1 antibodies by Wen-Ting K. Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J. Carter

“…A panel of related monospecific and bispecific IgG1 antibodies was constructed and assessed for immunogenicity risk by comparison with benchmark antibodies with known low (Avastin and Herceptin) or high (bococizumab and ATR-107) clinical incidence of anti-drug antibodies. …”
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广东省2009-2012年呼吸道合胞病毒的流行病学特征

“…【目的】 对急性呼吸道感染症状病人中呼吸道合胞病毒(RSV)流行情况进行监测,分析RSV在广东地区的流行特征,为今后广东地区RSV的监控和防治提供参考资料?【方法】 2009年7月至2012年6月期间在广东省25家哨点医院采集急性呼吸道感染病例咽拭子标本,提取标本RNA,反转录成cDNA,利用巢式PCR进行RSV检测;对RSV阳性标本进行其他6种呼吸道病毒的检测,了解混合感染情况?…”
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Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy by Lingling Xu, Weihong Yu, Meng Niu, Caixia Zheng, Bin Qu, Yan Li, Jing Wang, Ping Huang, O. Wang, Fengying Gong

“…The probability of the eGFR<90 mL/min/1.73 m2 in patients with the high ZAG levels was 94% higher than those with the low serum ZAG levels after adjusting for age, gender, and education [OR = 1.94, 95% CI (1.17–3.23), P=0.0094]. This phenomenon was more likely to be observed in the condition of uACR ≥ 2.7 mg/mmol, WC ≥ 90 cm for men, or WC ≥ 85 cm for women. …”
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Experimental and Theoretical Study on the False Positive of Monomethyltin Determination in Toys Based on Gastric Juice Migration by Lina Huang, Hanke Li, Yuhang Li, Peng Ren, Lezhou Yi, Yang Chen, Tongmei Ma

“…With metal tin powder as a representative of inorganic tin which existed in real samples, it was treated with artificial gastric juice (0.07 mol/L·HCl), followed by ethyl derivatization using sodium tetraethylborate [NaB(Et)4] and then analyzed by gas chromatography-mass spectrometry (GC-MS) according to the procedure specified in the standard of EN 71-3:2013+A3:2018 issued by the European Committee for Standardization (CEN). …”
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Efficacy of laparoscopic cardiectomy combined with side overlap anastomosis for the treatment of terminal achalasia by Jing-Tao Wang, Yu-Xiang Sun, Rui-Xin Li, Yun-Fei Zhang, Heng-Xuan Ding, Guo-Jun Wang, Bu-Lang Gao

“…The effective rates at 1 month, 6 and 12 months after surgery were 100% (95% CI: 100% -100%), 96% (95% CI: 87.7 -100%), and 92% (95% CI: 80.6 -100%). …”
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App-Based Ecological Momentary Assessment of Problematic Smartphone Use During Examination Weeks in University Students: 6-Week Observational Study by Ji Seon Ahn, InJi Jeong, Sehwan Park, Jooho Lee, Minjeong Jeon, Sangil Lee, Gangho Do, Dooyoung Jung, Jin Young Park

“…The regression analysis revealed significant positive associations between PSU and several factors, including depression (Patient Health Questionnaire-9; odds ratio [OR] 8.48, 95% CI 1.95-36.87; P=.004), social interaction anxiety (Social Interaction Anxiety Scale; OR 4.40, 95% CI 1.59-12.15; P=.004), sleep disturbances (General Sleep Disturbance Scale; OR 3.44, 95% CI 1.15-10.30; P=.03), and longer sleep duration (OR 3.11, 95% CI 1.14-8.48; P=.03). …”
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Predicting positive Clostridioides difficile test results using large-scale longitudinal data of demographics and medication history by Anh Pham, Robert El-Kareh, Frank Myers, Lucila Ohno-Machado, Tsung-Ting Kuo

“…These human-interpretable models can help distinguish significant predictors that affect a patient's chance of testing positive, which may influence their Clostridioides difficile risk.…”
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The Association between ER, PR, HER2, and ER−/PR+ Expression and Lung Cancer Subsequent in Breast Cancer Patients: A Retrospective Cohort Study Based on SEER Database by Hong Yu Shao, Bao Tan Hao, Feng Xiao Gao

“…ER+ and ER−/PR+ were detected no significant relationship with BC-LuC (ORs = 1.03, 95% CI: 0.87–1.22, p = 0.718 and ORs = 1.02, 95% CI: 0.61–1.72, p = 0.936, respectively). …”
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Exploration of pulse wave analysis under reactive hyperemia and close to an arteriovenous fistula: a comparative analysis by Veit Busch, Sandra Müller, Joachim Streis, Timm H. Westhoff, Thomas Felderhoff, Felix S. Seibert, Stefan Reuter, Niklas Mueller

“…Methods Subjects underwent local peripheral tonometric pulse wave analysis with the SphygmoCor® device and duplex sonography to assess flow velocity (peak Vmax and diastolic Vdiast) under physiological conditions. …”
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Instituto de Investigaciones en Procesos Tecnológicos Avanzados, Universidad Nacional del Chaco Austral. Presidencia Roque Sáenz Peña, Chaco, Argentina by Sebastiana Failla, Michela Contò, Antonio Borghese, Vittoria Lucia Barile

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Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

“…Rest and exercise-stress echocardiography, CMR and right heart catheterisation were performed at baseline. …”
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The influence of neurovegetative and psychological characteristics of infertile patients with long-term COVID-19 on the effectiveness of assisted reproductive technologies by O.G. Boichuk, I.S. Golovchak, T.V. Kolomiichenko

“…Symptoms that are typical for "long-COVID-19" are most often noted: reduced work capacity/fatigue (82.5%), attack-like headaches (72.5%), difficulty breathing (47.5%), sleep disturbances (47 .5%). Unfavorable medico-social and psychological risk factors for the failure of ART programs in patients with "long-COVID-19" can be a point assessment of the autonomic dysfunction syndrome above 25 (OR=5.80, CI 1.22-27.64), anxiety (OR=5.80, CI 1.56-21.62), presence of depression (OR=4.20, CI 1.27-13.89), chronic somatic disease (OR=4.20, CI 1.30-13.62), conflict situations (OR=3.86, CI 1.24-12.04). …”
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High-Grade Cervical Intraepithelial Neoplasia: Impact of Colposcopic Lesion Area on Systemic Immune Responses by Mantoani PTS, Micheli DC, Jammal MP, Vieira JH, Michelin MA, Ferreira CGX, Silva HN, Murta EFC, Nomelini RS

“…In the multivariable analysis, the independent variables associated with colposcopic lesion area greater than 1cm2 were IL-1> 13.3 pg/mL and IL-12 ≤ 349.6 pg/mL [OR (95% CI) = 10.10 (1.50– 67.96); OR (95% CI)=10.70 (1.17– 97.45), respectively].Conclusion: Although CIN 2/3 is a local uterine cervix lesion, there is a systemic immunological response. …”
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Multiple time points for detecting circulating tumor DNA to monitor the response to neoadjuvant therapy in breast cancer: a meta-analysis by Shuyi Niu, Tie Sun, Mozhi Wang, Litong Yao, Tianyi He, Yusong Wang, Hengjun Zhang, Xiang Li, Yingying Xu

“…The results demonstrated that ctDNA negativity was associated with pCR at T1 (OR = 0.34; 95% CI: 0.21–0.57), MT (OR = 0.35; 95% CI: 0.20–0.60), and EOT (OR = 0.38; 95% CI: 0.22–0.66). …”
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Chronic Deep Brain Stimulation of the Hypothalamic Nucleus in Wistar Rats Alters Circulatory Levels of Corticosterone and Proinflammatory Cytokines by Juan Manuel Calleja-Castillo, Dora Luz De La Cruz-Aguilera, Joaquín Manjarrez, Marco Antonio Velasco-Velázquez, Gabriel Morales-Espinoza, Julia Moreno-Aguilar, Maria Eugenia Hernández, Lucinda Aguirre-Cruz, Lenin Pavón

“…We included the respective control (C) and sham (S) groups (n=6 rats per group). DBS treated rats had higher levels of TNF-α (120%; P<0.01) and IFN-γ (305%; P<0.001) but lower corticosterone concentration (48%; P<0.001) than C and S. …”
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48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse by Wen-xiong Xu, Qian Zhang, Xiang Zhu, Chao-shuang Lin, You-ming Chen, Hong Deng, Yong-yu Mei, Zhi-xin Zhao, Dong-ying Xie, Zhi-liang Gao, Chan Xie, Liang Peng

“…Age (OR = 1.06, 95% CI = 1.02–1.10; p=0.003), the HBsAg level (OR = 2.21, 95% CI = 1.47–3.32; p<0.001), and positive origin HBeAg status (OR = 0.32, 95% CI = 0.14–0.74; p=0.008) were predictive factors to virologic relapse. …”
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Mineralized Granitic Porphyry of the Yangla Copper Deposit, Western Yunnan, China: Geochemistry of Fluid Inclusions and H-O, S, and Pb Isotopes by Xinfu Wang, Bo Li, ShenJin Guan, Olivier Nadeau, Guo Tang

“…Quartz-hosted fluid inclusions from the recently discovered granitic porphyry have homogenization temperature averaging around 180±20°C and 300±20°C with salinities ranging from 4 to 22 wt.% NaCleq, pointing toward the contribution of medium temperature-medium salinity and low temperature-low salinity fluids during the metallogenesis. …”
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