Effect of KRAS mutation status on clinicopathological characteristics and overall survival in patients with rectal cancer by Shengbin Zheng, Zhijie You, Guodon Guo, Zhijing Lin, Siming Wang, Guohua Yang

“…Retrospectively registered K2024-07-037.2024,7.…”
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Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II) by Jaeseong Jo, Chung Mo Nam, Jae Woong Sull, Ji Eun Yun, Sang Yeun Kim, Sun Ju Lee, Yoon Nam Kim, Eun Jung Park, Heejin Kimm, Sun Ha Jee

“…Furthermore, the risk of CRC significantly increased for individuals with a family history of CRC in the highest quartile of GRS when compared to subjects without a family history of CRC in the lowest quartile of GRS (counted GRS odds ratio [OR], 47.9; 95% confidence interval [CI], 4.9 to 471.8 for men; OR, 22.3; 95% CI, 1.4 to 344.2 for women) (weighted GRS OR, 35.9; 95% CI, 5.9 to 218.2 for men; OR, 18.1, 95% CI, 3.7 to 88.1 for women). …”
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Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05 by Yao Dong, Mei Han, Yongmei Qi, Ying Wu, Zhipeng Zhou, Dacheng Jiang, Zhonghui Gai

“…ObjectiveThis study aimed to assess the impact of Lactiplantibacillus plantarum Lp05 (Lp05) on the gastrointestinal microbiome and pathophysiological status of mice infected with Helicobacter pylori (H. pylori), exploring its potential as a probiotic treatment for H. pylori infections.MethodsIn vitro, the interaction between Lp05 and H. pylori was analyzed using laser confocal and scanning electron microscopy. In vivo, C57BL/6 mice infected with H. pylori were treated with Lp05 and divided into six groups: control, model, quadruple therapy, and three dosage levels of Lp05 (2×107, 2×108, 2×109 CFU/mouse/day). …”
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Postural imbalance without visual input is associated with specific neuropsychological deficits in older adults – results from the LIFE-adult study by Eva Grill, Andreas Zwergal, Andreas Zwergal, Dorothee Saur, Julian Klingbeil, Christopher Fricke, Florian Schöberl, Karim Felfela, Karim Felfela, Andrea Zülke, Steffi Riedel-Heller, Joseph Classen

“…All models were adjusted for sex, age, ApoE status, socioeconomic status, anamnestic stroke, and diabetes.ResultsIn total, we analyzed 460 participants with a mean age of 68.6 years, range 60 to 80, 47.6% female. A higher Romberg’s ratio for sway area was a significant indicator for impaired visuospatial abilities as measured by the dichotomized JLO (Odds Ratio = 1.42, 95% confidence interval 1.07 to 1.88). …”
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Methodological Guidelines of the Scientific Community for Human Microbiome Research (CHMR) and the Russian Gastroenterology Association (RGA) on the Use of Probiotics, Prebiotics,... by V. T. Ivashkin, A. V. Gorelov, D. I. Abdulganieva, O. P. Alekseeva, S. A. Alekseenko, A. Yu. Baranovsky, I. N. Zakharova, O. Yu. Zolnikova, K. V. Ivashkin, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammaev, S. V. Nikolaeva, E. A. Poluektova, A. S. Trukhmanov, D. V. Usenko, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, I. V. Berezhnaya, T. L. Lapina, R. V. Maslennikov, N. G. Sugian, A. I. Ulyanin

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Optimizing lipopeptide bioactivity: The impact of non-ionic surfactant dressing by Ágnes Ábrahám, Gergő Gyulai, Judith Mihály, Andrea Horváth, Orsolya Dobay, Zoltán Varga, Éva Kiss, Kata Horváti

“…In our study, we experimented with different types and systematically investigated the variation of the critical micelle concentration (CMC) of poloxamers at 25 and 37 °C in different media. …”
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Exposure to indoor and outdoor air pollution among children under five years old in urban area by A.K.R. Kouao, E.T. N’datchoh, V. Yoboue, S. Silue, H. Attoh, M. Coulibaly, T. Robins

“…Indoor air pollution associated with cooking and heating biomass fuel burning is estimated to be responsible for 7 million deaths in 2016 and most of these deaths occur in low and middle income countries. …”
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Radiolabeled Anti-Adenosine Triphosphate Synthase Monoclonal Antibody as a Theragnostic Agent Targeting Angiogenesis by Bok-Nam Park PhD, Su Jin Lee MD, PhD, Jung Hyun Roh MS, Kyung-Han Lee MD, PhD, Young-Sil An MD, PhD, Joon-Kee Yoon MD, PhD

“…The highest tumor uptake of 125 I-ATPS mAb in MKN-45 tumor-bearing mice was achieved 24 hours after injection (6.26% ± 0.47% injected dose [ID]/g), whereas tumor to muscle and tumor to blood ratios peaked at 48 hours. …”
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Buffalo whey proteins performance at the oil/water interface: rheology characterization of the interfacial films by Leandro F. Bustos, Víctor M. Pizones Ruiz-Henestrosa, Cecilio Carrera Sánchez, Franco E. Vasile, Oscar E. Pérez

“…Plate tensiometry showed that πeq of BWPC and WPC solutions increased from 9.9 to 16.7 mN/m and 11.5 to 15.0 mN/m, respectively, and conform protein concentration increased. …”
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Sequential Docetaxel in ≥7 Cycles Followed by Cabazitaxel Improves Oncological Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer by Seiichi Kato, Manabu Takai, Koji Iinuma, Shota Fujimoto, Masahiro Nakano, Takashi Ishida, Masahiro Uno, Masayoshi Tamaki, Mitsuhiro Taniguchi, Hisao Komeda, Yoshito Takahashi, Takuya Koie

“…Conclusions. Administration of ≥7 cycles of DOC followed by CBZ may improve oncological outcomes in patients with mCRPC.…”
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Diagnostic accuracy in coronary CT angiography analysis: artificial intelligence versus human assessment by James K Min, Paul Knaapen, Nick S Nurmohamed, Erik S G Stroes, Andrew D Choi, Ibrahim Danad, James Earls, Michiel J Bom, Ruben W de Winter, Rachel Bernardo, Ruurt Jukema, Ralf Sprengers

“…This study evaluated a novel algorithm for coronary stenosis quantification (atherosclerosis imaging quantitative CT, AI-QCT).Methods The study included 208 patients with suspected coronary artery disease (CAD) undergoing CCTA in Perfusion Imaging and CT Coronary Angiography With Invasive Coronary Angiography-1. …”
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Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment by Sunisa Khongthong, Pipat Piewngam, Natthrit Roekngam, Prapot Maliwan, Sonsawan Kongpuckdee, Juthatip Jeenkeawpleam, Prawit Rodjan

“…The results indicated that dietary supplementation with B. subtilis spores at concentrations of 1 × 106 CFU/g of feed (BS6 group) and 1 × 107 CFU/g of feed (BS7 group) improved body weight and body weight gain during d 0–42 (P < 0.05), while the feed intake of the BS7 group was highest (P < 0.05). …”
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Improving apgar scores and reducing perineal injuries through midwife-led quality improvements: an observational study in Uganda by Johanna Blomgren, Michael B. Wells, Dinah Amongin, Kerstin Erlandsson, John Wanyama, Diana A. Afrifa, Helena Lindgren

“…Newborns with an Apgar score below seven at five minutes were significantly associated with intrapartum support [AOR; 0.8 (95% CI 0.7 – 1.0)] and perineal protection [AOR; 0.3 (95% CI 0.1 – 0.8)]. …”
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Dengue dynamics, predictions, and future increase under changing monsoon climate in India by Yacob Sophia, Mathew Koll Roxy, Raghu Murtugudde, Anand Karipot, Amir Sapkota, Panini Dasgupta, Kalpana Baliwant, Sujata Saunik, Abhiyant Tiwari, Rajib Chattopadhyay, Revati K. Phalkey

“…Additionally, warm temperatures above 27°C and humidity levels between 60% and 78% elevate the risk of dengue. …”
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Expresión de HIF-1α en el frente invasivo del carcinoma de células escamosas orales y  su relación con la transición epitetelio-mesénquima by Felipe Martins Silveira, Lauren Frenzel Schuch, Vanesa Pereira Prado, Estefanía Sicco, Ronell Bologna-Molina

“…En cuanto a las áreas de frente de invasión, se encontró una correlación estadísticamente significativa entre una expresión alta de HIF-1α citoplasmático y nuclear, asociada con una alta expresión de Vimentina y E-cadherina (p=0.007). …”
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Maximizing the performance of heat stressed broilers by optimizing starch-to-lipid ratios, digestible amino acid, and metabolizable energy during the finisher phase by Dilshaan Duhra, Denise Beaulieu, Tory Shynkaruk, Juliano C. de Paula Dorigam, Rose Whelan, Karen Schwean-Lardner

“…Three basal finisher diets were formulated to have the highest S:L ratio (Basal A; 20:1), DigLys (Basal B; 1.30 %), or AME (Basal C; 3300 kcal/kg). These diets were blended at levels of 0.00, 0.33, 0.67, or 1.00 to produce 10 finisher diets. …”
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Influence of elevated temperature exposure on the residual compressive strength and radiation shielding efficiency of ordinary concrete incorporating granodiorite and ceramic powde... by Alaa A. Mahmoud, Alaa A. El-Sayed, Ayman M. Aboraya, Islam N. Fathy, Mohamed A. Abouelnour, Maged E. Elfakharany, Mohy S. Fattouh, Abdelmoniem E. Alahmer, Islam M. Nabil

“…Results revealed a substantial improvement in the investigated properties of the concrete. Remarkably, a 7% substitution with waste granodiorite powder (WGDP) yielded the optimal mix for compressive strength, exhibiting increases of 24.7%, 26.1%, 22%, and 28% at room temperature, 400 °C, 600 °C, and 800 °C, respectively. …”
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Apallic syndrome of toxic origin: the diagnostic criteria by N.V. Kurdil, A.O. Volosovets, O.V. Ivashchenko, V.S. Lisovska, H.M. Balan, O.M. Rozhkova, V.V. Andriushchenko

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A phase I, randomized, placebo‐controlled trial to evaluate the pharmacokinetics, safety, and tolerability of nirsevimab in healthy Chinese adults by Xiaomeng Mao, Xiaohan Hua, Chengyi Wu, Xiaoyun Ge, Jie Zhang, Xiaojie Wu, Robert J. Kubiak, Ulrika Wählby Hamrén, Tonya Villafana, Georgios Christou, Jannine Green, Therese Takas, Yuwen Jin

“…Nirsevimab geometric mean (coefficient of variation [%CV]) Cmax was 46.9 (21.7) μg/mL, median (range) tmax was 7.0 (4.9, 29.9) days, and geometric mean (%CV) AUC0–150 was 4210.6 (13.6) μg·day/mL. …”
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Process Optimization and Antioxidant Activity Analysis of White Kidney Bean Polypeptides Prepared by Composite Strain Fermentation by Sinan LI, Meng WANG, Yu AN, Qing WANG, Kaiyuan XU, Jia WANG, Zhihui ZHANG, Xi WANG, Ying WANG, Lu ZHANG

“…Shipin gongye ke-ji…”
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